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1. 发明授权

EP2562155B1 HYDROXAMIC ACID DERIVATIVE 有权
公开(公告)号：EP2562155B1
公开(公告)日：2019-06-05
申请号：EP11772045.8
申请日：2011-04-20
申请人： Taisho Pharmaceutical Co., Ltd. , FUJIFILM Toyama Chemical Co., Ltd.
发明人： TAKASHIMA, Hajime , TSURUTA, Risa , YABUUCHI, Tetsuya , OKA, Yusuke , URABE, Hiroki , SUGA, Yoichiro , TAKAHASHI, Masato , UNEUCHI, Fumito , KOTSUBO, Hironori , SHOJI, Muneo , KAWAGUCHI, Yasuko
IPC分类号： C07C259/06 , A61K31/166 , A61K31/337 , A61K31/341 , A61K31/343 , A61K31/351 , A61K31/357 , A61K31/36 , A61K31/381 , A61K31/397 , A61K31/40 , A61K31/4015 , A61K31/402 , A61K31/403 , A61K31/4035 , A61K31/404 , A61K31/4045 , A61K31/407 , A61K31/415 , A61K31/416
CPC分类号： C07C233/83 , C07C235/84 , C07C237/36 , C07C259/06 , C07C271/22 , C07C271/28 , C07C309/30 , C07C311/08 , C07C317/28 , C07C317/44 , C07C323/41 , C07C323/62 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/08 , C07D205/04 , C07D205/12 , C07D207/10 , C07D207/12 , C07D207/27 , C07D207/327 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/44 , C07D209/52 , C07D211/14 , C07D211/18 , C07D211/38 , C07D211/46 , C07D211/56 , C07D211/70 , C07D213/38 , C07D213/40 , C07D213/54 , C07D213/61 , C07D213/64 , C07D213/65 , C07D213/70 , C07D213/74 , C07D213/81 , C07D215/14 , C07D217/04 , C07D217/12 , C07D231/12 , C07D231/56 , C07D233/61 , C07D235/04 , C07D257/04 , C07D261/08 , C07D263/14 , C07D263/32 , C07D263/56 , C07D265/30 , C07D265/36 , C07D265/38 , C07D267/10 , C07D271/12 , C07D277/20 , C07D277/30 , C07D277/62 , C07D277/66 , C07D285/12 , C07D295/08 , C07D295/12 , C07D295/14 , C07D295/16 , C07D305/06 , C07D305/08 , C07D307/14 , C07D307/18 , C07D307/52 , C07D307/54 , C07D307/78 , C07D307/81 , C07D307/82 , C07D307/87 , C07D309/04 , C07D309/14 , C07D317/30 , C07D317/60 , C07D319/18 , C07D319/20 , C07D333/24 , C07D405/06 , C07D413/06 , C07D471/04 , C07D471/10 , C07D487/08 , C07D491/20 , C07D498/04 , C07D498/08 , C07F9/091
摘要： Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria. Provided is a hydroxamic acid derivative represented by the following general formula [1] or a pharmaceutically acceptable salt thereof:

2. 发明公开

EP3152189A4 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO 审中-公开
公开(公告)号：EP3152189A4
公开(公告)日：2017-12-20
申请号：EP15806420
申请日：2015-06-08
申请人： DOW AGROSCIENCES LLC
发明人： LEPLAE PAUL RENEE , HUNTER JAMES E , WATSON GERALD B , LO WILLIAM C , HERBERT JOHN
IPC分类号： C07C233/66 , A01N33/08 , A01N37/20 , A01N37/26 , A01N37/28 , A01N37/34 , A01N37/36 , A01N37/44 , A01N41/10 , A01N53/00 , C07C225/16 , C07C233/78 , C07C243/38 , C07C251/40 , C07C255/19 , C07C255/46 , C07C317/28 , C07C317/44 , C07C323/41 , C07C323/60
CPC分类号： C07C225/16 , A01N33/08 , A01N37/18 , A01N37/20 , A01N37/26 , A01N37/28 , A01N37/34 , A01N37/36 , A01N37/44 , A01N41/10 , A01N53/00 , C07B2200/07 , C07C233/78 , C07C233/83 , C07C243/38 , C07C255/19 , C07C255/46 , C07C317/28 , C07C317/44 , C07C323/41 , C07C323/60 , C07C2601/02
摘要： This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules, and processes of using such molecules against such pests. These molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses molecules having the following formula (“Formula One”).

3. 发明授权

EP3057444B1 ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES 有权
公开(公告)号：EP3057444B1
公开(公告)日：2017-12-06
申请号：EP13773224.4
申请日：2013-10-02
申请人： Givaudan SA
发明人： DE KLERK, Adri , WINKEL, Cornelis
IPC分类号： A23L27/00 , A23L27/20 , C07C237/00 , C07C207/04
CPC分类号： C07C237/16 , A23L27/202 , A23L27/2022 , A23L27/203 , A23L27/204 , A23L27/2054 , A23L27/88 , A23V2002/00 , C07C233/58 , C07C237/06 , C07C323/41 , C07C323/60 , C07D207/16

4. 发明公开

EP3207929A2 COLCHICINE DERIVATIVES 有权转让
标题翻译：醋酸衍生物
公开(公告)号：EP3207929A2
公开(公告)日：2017-08-23
申请号：EP16198280.6
申请日：2004-04-14
申请人： California Pacific Medical Center , Catholic Healthcare West, d.b.a. St. Mary's Medical Center
发明人： YANG, Li-Xi
IPC分类号： A61K31/4439 , A61K31/433 , A61K31/403 , A61K31/155 , A61K31/175 , C07C323/41 , C07C323/42 , C07C323/60 , C07H5/06 , C07D295/15
CPC分类号： C07C323/41 , C07C323/42 , C07C323/60 , C07C2603/18 , C07C2603/24 , C07C2603/34 , C07D295/15 , C07H5/06
摘要： Certain N-deacetylcolchicine and N-deacetylthiocolchine derivatives are described wherein the 7-N position on the B ring is substituted with the group - C(O)-(CHR 4 ) m -AR, wherein m is an integer of 0-10, A is S, O, N or a covalent bond; R 1 is substituted phenyl or substituted benzoyl; optionally substituted cycloalkyl of 3-7 carbons; optionally substituted naphtyl; an optionally substituted imide ring; an optionally substituted 5 or 6 member heterocycle with at least one N, S, or O in the ring; or an optionally substituted fused heterocyclic or fused carboxyclic ring system; R 2 (at the 2-position of the A ring) is methoxy, hydroxy, or methylenedioxy when taken together with R 3 ; R 3 (at the 3-position of the A ring) is methoxy, hydroxy, a monosaccharide radical, or is methylenedioxy when taken together with R 2 ; and R 4 is H or is H or methyl when m is 1. Also dimers of such compounds are disclosed. When combined with suitable pharmaceutical excipients, these compounds are useful for treating various types of cancer.
摘要翻译：描述了某些N-去乙酰基秋水仙碱和N-脱乙酰硫代秋水仙碱衍生物，其中B环上的7-N位被基团-C（O） - （CHR4）m-AR取代，其中m是0-10的整数，A 是S，O，N或共价键; R1是取代的苯基或取代的苯甲酰基; 任选取代的3-7个碳的环烷基; 任选取代的萘基; 任选取代的酰亚胺环; 在环中具有至少一个N，S或O的任选取代的5或6元杂环; 或任选取代的稠合杂环或稠合羧基环体系; R2（在A环的2-位）与R3结合时为甲氧基，羟基或亚甲二氧基; R3（在A环的3-位）是甲氧基，羟基，单糖基团，或当与R2一起时是亚甲二氧基; 当m是1时，R4是H或是H或甲基。还公开了这些化合物的二聚体。当与合适的药物赋形剂组合时，这些化合物可用于治疗各种类型的癌症。

5. 发明授权

EP1617843B1 COLCHICINE DERIVATIVES 有权
标题翻译：秋水仙碱衍生物
公开(公告)号：EP1617843B1
公开(公告)日：2016-12-21
申请号：EP04775891.7
申请日：2004-04-14
申请人： California Pacific Medical Center , Catholic Healthcare West, d.b.a. St. Mary's Medical Center
发明人： YANG, Li-Xi
IPC分类号： C07C323/42 , C07C323/41 , C07C323/60 , C07D295/15 , A61K31/4439 , A61K31/433 , A61K31/403 , C07H5/06
CPC分类号： C07C323/41 , C07C323/42 , C07C323/60 , C07C2603/18 , C07C2603/24 , C07C2603/34 , C07D295/15 , C07H5/06

7. 发明授权

EP2634135B1 SYNTHESIS OF MOLECULAR SIEVES FOR MODIFYING THE SURFACES OF NANOPARTICLES HAVING AMPHOTERIC IONS, AND APPLICATION THEREOF 有权
标题翻译：分子七为纳米颗粒的表面活性剂与两性离子及其用途改性合成
公开(公告)号：EP2634135B1
公开(公告)日：2016-04-27
申请号：EP11836648.3
申请日：2011-10-28
申请人： Postech Academy-Industry- Foundation
发明人： KIM, Sungjee , PARK, Joonhyuck , NAM, Jutaek , JIN, Ho
IPC分类号： B82B3/00 , B82B1/00 , A61K49/00 , A61K49/18 , C07C319/06 , C07C323/41
CPC分类号： C07C323/41 , B82B1/005 , C07C319/06

9. 发明授权

EP2776482B1 PROCEDE DE PREPARATION DE PARTICULES APTES A CATALYSER LA REDUCTION DE L'OXYGENE OU L'OXYDATION DE L'HYDROGENE CONDUCTRICES DE PROTONS 有权
标题翻译：制造质子导电粒子的方法来促进氧的还原或氧化氢的
公开(公告)号：EP2776482B1
公开(公告)日：2015-10-07
申请号：EP12780502.6
申请日：2012-11-05
申请人： Commissariat à l'Énergie Atomique et aux Énergies Alternatives , Centre National de la Recherche Scientifique
发明人： BUVAT, Pierrick , FERRANDEZ, Anne-Claire , BARENTON, Steve , COUTANCEAU, Christophe
IPC分类号： C08F292/00 , C07C321/24 , C08F2/38 , H01M4/92 , H01M4/90
CPC分类号： B01J31/123 , C07C323/41 , C08F2/38 , C08F292/00 , C08F2438/01 , H01M4/9008 , H01M4/926 , H01M2008/1095 , Y02E60/50 , C08F212/14

10. 发明授权

EP2370269B1 PATTERNING PROCESS 有权
标题翻译： MUSTERBILDUNGSPROZESS
公开(公告)号：EP2370269B1
公开(公告)日：2015-08-05
申请号：EP09832396.7
申请日：2009-12-02
申请人： 3M Innovative Properties Company
发明人： ZU, Lijun , FREY, Matthew H. , IYER, Suresh
IPC分类号： G03F7/00 , B44C1/22 , H01L21/64 , B82Y30/00 , B82Y40/00 , C07C323/41 , C07C323/52 , C07C323/60 , C08G65/00 , C09D171/02 , C08G65/334 , B05D1/18 , B82Y10/00
CPC分类号： C07D303/48 , B05D1/185 , B82Y10/00 , B82Y30/00 , B82Y40/00 , C07C323/41 , C07C323/52 , C07C323/60 , C08F2/38 , C08G65/007 , C08G65/334 , C09D171/02 , G03F7/0002
摘要： A patterning process comprises (a) providing at least one substrate having at least one major surface; (b) providing at least one patterning composition comprising at least one functionalizing molecule that is a perfluoropolyether organosulfur compound; (c) applying the patterning composition to the major surface of the substrate in a manner so as to form at least one functionalized region and at least one unfunctionalized region of the major surface; and (d) etching at least a portion of the unfunctionalized region.
摘要翻译：图案化工艺包括（a）提供至少一个具有至少一个主表面的基材; （b）提供至少一种图案化组合物，其包含至少一种作为全氟聚醚有机硫化合物的官能化分子; （c）以形成主表面的至少一个官能化区域和至少一个未官能化区域的方式将图案形成组合物施加到基材的主表面; 和（d）蚀刻非功能化区域的至少一部分。

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