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1. 发明授权

EP3094308B1 PROCESS FOR PRODUCING EMD OF INCREASED STABILITY 审中-公开
公开(公告)号：EP3094308B1
公开(公告)日：2018-12-26
申请号：EP15702962.0
申请日：2015-01-19
申请人： Straumann Holding AG
发明人： APICELLA, Alessandra , HEUNEMANN, Peggy
IPC分类号： A61K8/64 , A61Q11/00 , A61K8/73 , A61K38/17 , A61K6/00 , A61K6/027
CPC分类号： A61K6/0038 , A61K6/0041 , A61K6/0047 , A61K6/0067 , A61K6/027 , A61K8/36 , A61K8/44 , A61K8/64 , A61K8/733 , A61K8/735 , A61K35/32 , A61K38/17 , A61K47/183 , A61K47/61 , A61K2800/52 , A61K2800/591 , A61K2800/60 , A61K2800/805 , A61K2800/84 , A61Q11/00
摘要： The present invention relates to a process for producing a pharmaceutical, dental and/or cosmetic formulation comprising purified enamel matrix proteins and/or enamel matrix derivative (EMD) proteins, which is heat stable. In particular, the present invention is related to a process for producing stable formulations of enamel matrix proteins and/or enamel matrix derivative (EMD) proteins, wherein said proteins and/or derivatives are solved in a low pH formulation before being subjected to a heat-treatment step.

2. 发明公开

EP3185857A4 BONDABLE MICROCAPSULES AND SURFACE FUNCTIONALIZED FILLERS 审中-公开
公开(公告)号：EP3185857A4
公开(公告)日：2018-05-02
申请号：EP15843335
申请日：2015-09-24
申请人： PREMIER DENTAL PRODUCTS CO
发明人： GROSS STEPHEN M , MCHALE WILLIAM A , LATTA MARK A
IPC分类号： A61K9/50 , A61K6/083 , A61K31/13 , A61K31/435 , A61K47/02 , A61K47/30 , C01B7/20 , C01B25/26 , C01F11/00
CPC分类号： A61K6/083 , A61K6/0052 , A61K6/0067 , A61K6/0076 , A61K6/0082 , A61K6/0091 , A61K6/09 , A61K6/093 , A61K31/14 , A61K31/4425 , A61K33/18 , B01J13/16 , C01B9/08 , C08F290/067 , C08G18/3203 , C08G18/672 , C08G18/72 , C08G18/8175
摘要： A composition comprising microcapsules functionalized with polymerizable functional groups on the surface of said microcapsules wherein the functional groups form covalent bonds with monomers in the continuous phase to enhance the mechanical properties of the composition.

3. 发明公开

EP3171849A4 PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS 审中-公开
公开(公告)号：EP3171849A4
公开(公告)日：2018-04-04
申请号：EP15825425
申请日：2015-07-24
申请人： THE UNIV OF MARYLAND BALTIMORE
发明人： XU HUAKUN , ZHANG NING
IPC分类号： A61K6/02 , A61K6/00 , A61K6/027 , A61K6/08 , A61K31/685
CPC分类号： A61K6/0067 , A61K6/0017 , A61K6/0029 , A61K6/007 , A61K31/685 , A61K6/0023 , C08L33/08 , A61K6/0026
摘要： The present invention provides protein-repellent dental materials that can be widely applied in a variety of dental applications. The protein-repellent dental materials of the invention include dental primers, dental adhesives, dental resins, dental composites, dental bonding systems and the like, as well as dental cements, dental sealants, dental bases and dental liners, each of which is protein-repellent and each of which comprises a protein-repellent agent. In certain aspects, the protein-repellent agent is 2-methacryloyloxyethyl phosphorylcholine (MPC).

4. 发明公开

EP3137011A4 ENDODONTIC TREATMENT WITH LONG TERM DRUG DELIVERY SYSTEM 审中-公开
公开(公告)号：EP3137011A4
公开(公告)日：2018-01-03
申请号：EP15785553
申请日：2015-04-29
申请人： DENTSPLY INT INC
发明人： AMMON DAN , WILKINSON KEVIN , GUTMANN JAMES L
IPC分类号： A61C5/48 , A61K6/00
CPC分类号： A61K6/0067 , A61C5/40 , A61K6/0038
摘要： Disclosed is an endodontic treatment of an infected root canal with a drug delivery system in order to prevent the need for a root canal treatment of a patient.

5. 发明公开

EP3232981A1 DENTAL IMPLANT 审中-公开
标题翻译：牙种植体
公开(公告)号：EP3232981A1
公开(公告)日：2017-10-25
申请号：EP15816124.0
申请日：2015-12-14
申请人： Nobel Biocare Services AG
发明人： MEMMOLO, Marcello , JAN, Hall , DE HALLER, Emmanuel
IPC分类号： A61C8/00
CPC分类号： A61C8/0015 , A61C8/0013 , A61K6/0067 , A61K6/0235 , A61K6/04
摘要： The present invention discloses a dental implant configured to be inserted in a hole in jaw bone and to be at least partially situated in the bone tissue when implanted and comprises: a coronal region, an apical region, a longitudinal axis extending from the coronal region of the dental implant to the apical region of the dental implant; an implant surface configured to form an interface between an implant material and the oral environment/surrounding tissue and a surface layer formed on at least part of said implant surface, said surface layer comprising crystalline titanium oxide in the anatase phase and wherein the surface area roughness Sa and the pore size of the implant surface on which said surface layer is formed increase from the coronal region toward the apical region of the dental implant along the longitudinal axis.
摘要翻译：本发明公开了一种牙科植入物，其被构造成插入颚骨中的孔中并且在被植入时至少部分地位于骨组织中并且包括：冠状区域，顶点区域，从所述冠状区域牙齿植入物到牙齿植入物的顶端区域; 植入物表面，其被配置为形成植入物材料与口腔环境/周围组织之间的界面，以及在所述植入物表面的至少一部分上形成的表面层，所述表面层包含锐钛矿相中的晶体氧化钛，并且其中表面区域粗糙度 Sa以及其上形成有所述表面层的植入物表面的孔径沿着纵向轴线从牙冠植入物的冠部区域朝向尖端区域增加。

6. 发明公开

EP3216598A1 MEDICAL DEVICE, METHOD FOR PRODUCING MEDICAL DEVICE, AND MEDICAL DEVICE PRODUCING APPARATUS 审中-公开
标题翻译：医疗装置，医疗装置的制造方法以及医疗装置制造装置
公开(公告)号：EP3216598A1
公开(公告)日：2017-09-13
申请号：EP17159704.0
申请日：2017-03-07
申请人： Ricoh Company, Ltd.
发明人： WATANABE, Masaki , SAKURAI, Yoichi , SAITO, Takuya , NIIMI, Tatsuya
IPC分类号： B32B18/00 , C04B35/111 , C04B35/16 , C04B35/486 , C04B35/626 , C04B35/634 , B33Y80/00 , B33Y70/00 , B33Y10/00 , B28B1/00 , A61K6/00 , A61K6/02 , A61K6/027
CPC分类号： A61C8/0015 , A61C5/35 , A61C5/77 , A61C8/0006 , A61C8/0012 , A61C13/0013 , A61C13/0019 , A61C13/01 , A61C13/083 , A61C2008/0046 , A61K6/0008 , A61K6/0017 , A61K6/0067 , A61K6/024 , A61K6/0273 , A61L27/10 , A61L27/54 , A61L27/56 , A61L2430/12 , B28B1/001 , B29C64/165 , B29K2105/16 , B29K2509/02 , B29L2031/753 , B32B18/00 , B33Y10/00 , B33Y30/00 , B33Y70/00 , B33Y80/00 , C04B35/111 , C04B35/16 , C04B35/486 , C04B35/6264 , C04B35/6269 , C04B35/63416 , C04B35/63424 , C04B2235/3203 , C04B2235/5445 , C04B2235/5454 , C04B2235/6026 , C04B2235/775 , C04B2235/963 , A61K6/0023 , C08L33/08
摘要： Provided is a medical device including a porous portion and a dense portion, wherein an arithmetic average roughness of a surface of the porous portion is 2.0 µm or greater but 20 µm or less, and wherein an arithmetic average roughness of a surface of the dense portion is less than 2.0 µm.
摘要翻译：本发明提供一种医疗器具，其具有多孔质部和致密部，所述多孔质部的表面的算术平均粗糙度为2.0μm以上20μm以下，并且所述致密部的表面的算术平均粗糙度小于2.0μm。

7. 发明公开

EP3171849A1 PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS 审中-公开
标题翻译：蛋白质拒斥性牙科材料及其在牙科应用中的用途
公开(公告)号：EP3171849A1
公开(公告)日：2017-05-31
申请号：EP15825425.0
申请日：2015-07-24
申请人： The University of Maryland, Baltimore
发明人： XU, Huakun , ZHANG, Ning
IPC分类号： A61K6/02 , A61K6/027 , A61K6/08
CPC分类号： A61K6/0067 , A61K6/0017 , A61K6/0029 , A61K6/007 , A61K31/685 , A61K6/0023 , C08L33/08 , A61K6/0026
摘要： The present invention provides protein-repellent dental materials that can be widely applied in a variety of dental applications. The protein-repellent dental materials of the invention include dental primers, dental adhesives, dental resins, dental composites, dental bonding systems and the like, as well as dental cements, dental sealants, dental bases and dental liners, each of which is protein-repellent and each of which comprises a protein-repellent agent. In certain aspects, the protein-repellent agent is 2-methacryloyloxyethyl phosphorylcholine (MPC).
摘要翻译：本发明提供了可以广泛应用于各种牙科应用的抗蛋白质牙科材料。本发明的蛋白质 - 驱避剂牙科材料包括牙科用底剂，牙科用粘合剂，牙科用树脂，牙科用复合材料，牙科用粘合剂等，还有牙科用粘固剂，牙科用密封剂，牙科用基剂和牙科用衬里，它们各自包含蛋白质驱避剂。在某些方面，蛋白质驱避剂是2-甲基丙烯酰氧乙基磷酸胆碱（MPC）。

8. 发明公开

EP3137011A1 ENDODONTIC TREATMENT WITH LONG TERM DRUG DELIVERY SYSTEM 审中-公开
标题翻译： ENDODONTISCHE BEHANDLUNG MIT LANGZEITARZNEIMITTELAUSGABESYSTEM
公开(公告)号：EP3137011A1
公开(公告)日：2017-03-08
申请号：EP15785553.7
申请日：2015-04-29
申请人： Dentsply International Inc.
发明人： AMMON, Dan , WILKINSON, Kevin , GUTMANN, James, L.
IPC分类号： A61C5/48 , A61K6/00
CPC分类号： A61K6/0067 , A61C5/40 , A61K6/0038
摘要： Disclosed is an endodontic treatment of an infected root canal with a drug delivery system in order to prevent the need for a root canal treatment of a patient.
摘要翻译：公开了用药物递送系统对感染根管的根管治疗，以便防止对患者的根管治疗的需要。

9. 发明公开

EP3094308A1 PROCESS FOR PRODUCING EMD OF INCREASED STABILITY 审中-公开
标题翻译：用于生产EMD稳定性增加
公开(公告)号：EP3094308A1
公开(公告)日：2016-11-23
申请号：EP15702962.0
申请日：2015-01-19
申请人： Straumann Holding AG
发明人： APICELLA, Alessandra , HEUNEMANN, Peggy
IPC分类号： A61K8/64 , A61K38/00 , A61Q11/00 , A61K8/73 , A61K6/00
CPC分类号： A61K6/0038 , A61K6/0041 , A61K6/0047 , A61K6/0067 , A61K6/027 , A61K8/36 , A61K8/44 , A61K8/64 , A61K8/733 , A61K8/735 , A61K35/32 , A61K38/17 , A61K47/183 , A61K47/61 , A61K2800/52 , A61K2800/591 , A61K2800/60 , A61K2800/805 , A61K2800/84 , A61Q11/00
摘要： The present invention relates to a process for producing a pharmaceutical, dental and/or cosmetic formulation comprising purified enamel matrix proteins and/or enamel matrix derivative (EMD) proteins, which is heat stable. In particular, the present invention is related to a process for producing stable formulations of enamel matrix proteins and/or enamel matrix derivative (EMD) proteins, wherein said proteins and/or derivatives are solved in a low pH formulation before being subjected to a heat-treatment step.

10. 发明公开

EP2839849A4 BIOMATERIAL COATED WITH HAp/Col COMPOSITE 审中-公开
标题翻译： WITH A HAP / COL复合被覆生物材料
公开(公告)号：EP2839849A4
公开(公告)日：2015-11-18
申请号：EP13778464
申请日：2013-04-19
申请人： NAT INST FOR MATERIALS SCIENCE , NAT UNIV CORP TOKYO MED & DENT
发明人： KIKUCHI MASANORI , TAKAKUDA KAZUO , MORIYAMA KEIJI , SUZUKI SHOICHI , UEZONO MASAYOSHI
IPC分类号： A61L27/46 , A61K6/00 , A61L27/04 , A61L27/06 , A61L27/28
CPC分类号： A61L27/46 , A61K6/0067 , A61K6/0085 , A61K6/033 , A61K6/04 , A61L27/04 , A61L27/06 , A61L27/12 , A61L27/24 , A61L27/28 , A61L27/32 , A61L27/34 , A61L27/54 , A61L27/58 , A61L2300/112 , A61L2300/252 , A61L2300/412 , A61L2300/45 , A61L2300/606 , A61L2400/18 , A61L2420/02 , A61L2420/04 , A61L2420/06 , A61L2430/02 , C08L89/06

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