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    • 4. 发明公开
    • DEVICE FOR RECONSTITUTING A PHARMACEUTICAL COMPOSITION
    • VORRICHTUNG ZUR WIEDERHERSTELLUNG EINER PHARMAZEUTISCHEN ZUSAMMENSETZUNG
    • EP3099282A1
    • 2016-12-07
    • EP15702190.8
    • 2015-01-23
    • Eveon
    • WATTELIER, ArnaudPAYET-BURIN, Xavier
    • A61J1/20
    • A61J1/2093A61J1/1406A61J1/20A61J1/201A61J1/2017A61J1/2048A61J1/2068A61J1/2086A61J1/2096A61M5/142B65B31/02
    • The invention relates to a device (1) for reconstituting a pharmaceutical composition from at least a first component contained in a first container (2A) and a second component contained in a second container (2B), comprising: €¢ a fluidic unit (100) comprising: - a first connector (101) coupled to the first container (2A), - a second connector (102) coupled to the second container (2B), - a pump (103), - a fluidic circuit (104) connecting the first connector (101), the second connector (102) and the pump (103), wherein the first connector (101) comprises a crankpin (1011) in rotating engagement within a body (1010), said crankpin comprising a unique axial port (1011A) intended to fluidically couple to the first container, a radial port (1011 B) fluidically connected to said axial port (1011A), and at least one channel (1011C) arranged therein so as to cooperate with the radial ports of the body (1010) to selectively connect the axial port (1011A) of the first connector with at least one channel portion of the fluidic circuit (104) depending on the angular position of the crankpin (1011) with respect to the body (1010), €¢ a power unit (200) releasably coupled to the fluidic unit (100), comprising: - a power mechanism (203) for actuating the pump, - transmission means connected between an actuator and the crankpin (1011) for rotating the first container (2A).
    • 本发明涉及一种用于将药物组合物从至少包含在第一容器(2A)中的第一组分和包含在第二容器(2B)中的第二组分)重建的装置(1),包括:流体单元(100 )包括: - 耦合到所述第一容器(2A)的第一连接器(101), - 联接到所述第二容器(2B)的第二连接器(102), - 泵(103), - 流体回路(104) 第一连接器(101),第二连接器(102)和泵(103),其中第一连接器(101)包括在主体(1010)内旋转接合的曲柄销(1011),所述曲柄销包括独特的轴向端口 (1011A),其旨在流体地联接到所述第一容器,流体连接到所述轴向端口(1011A)的径向端口(1011B)以及布置在其中的至少一个通道(1011C),以与所述主体的径向端口配合 (1010),以选择性地连接第一连接器的轴向端口(1011A) 根据曲柄销(1011)相对于主体(1010)的角位置,流体回路(104)的一个通道部分,可拆卸地联接到流体单元(100)的动力单元(200),包括 - 用于致动所述泵的动力机构(203), - 连接在致动器和所述曲柄销(1011)之间用于旋转所述第一容器(2A)的传动装置。
    • 10. 发明公开
    • PRESSURE-REGULATING VIAL ADAPTORS
    • 一个PHIOLE的压力控制适配器
    • EP2744469A4
    • 2015-07-22
    • EP12823375
    • 2012-08-16
    • ICU MEDICAL INC
    • FANGROW THOMAS F
    • A61J1/20
    • A61J1/2096A61J1/10A61J1/201A61J1/2048A61J1/2075A61J1/2082A61J1/2086B65B3/003Y10T29/49826
    • In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. In some embodiments, the regulator assembly includes a flexible member configured to expand and contract in accordance with changes in the volume of the medical fluid in the vial. In some embodiments, the flexible member is substantially free to expand and contract. In some embodiments, the flexible member is not partly or completely located in a rigid enclosure.
    • 在某些实施例中,小瓶适配器包括被配置成将适配器与小瓶,进入通道,调节器通道和调节器组件连接的壳体。 进入通道被配置为当适配器联接到小瓶时便于从小瓶中取出流体。 调节器通道被配置为便于来自调节器组件的调节流体的流动以补偿小瓶中的医用流体的体积变化。 在一些实施例中,调节器组件包括柔性构件,其构造成根据小瓶中的医用流体的体积变化而膨胀和收缩。 在一些实施例中,柔性构件基本上可自由地膨胀和收缩。 在一些实施例中,柔性构件不是部分地或完全地位于刚性外壳中。