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1. 发明公开

EP1539273A4 DEVICE AND METHOD FOR DRUG DELIVERY TO ANIMALS 有权
标题翻译： VORRICHTUNG UND VERFAHRENFÜRDIE ARZNEIMITTELABGABE贝蒂伦
公开(公告)号：EP1539273A4
公开(公告)日：2006-09-06
申请号：EP03763376
申请日：2003-07-03
申请人： BIOANALYTICAL SYSTEMS INC
发明人： KISSINGER CANDICE B , HAMPSCH JAMES M , BOUGHER JOSEPH A
IPC分类号： A61D7/00 , A61M20060101 , A61M5/00 , A61M5/14 , A61M5/145 , A61M5/168 , A61M31/00
CPC分类号： A61B5/1427 , A61B5/14 , A61B5/15003 , A61B5/150221 , A61B5/150236 , A61B5/150244 , A61B5/150854 , A61B5/150862 , A61B5/15087 , A61B5/150992 , A61B5/153 , A61B5/155 , A61M5/1408 , A61M5/1456 , A61M5/16827 , A61M2205/11 , A61M2250/00 , Y02A90/26
摘要： A method for delivering a fluid to an animal with a drug delivery device without causing contamination to the drug delivery device. The drug delivery device used by the method may comprise a fluid subsystem with a switching device, disposable syringes, fluid reservoirs, disposable tubing, and a catheter. In one embodiment, the method allows a user to deliver multiple drugs to an animal without contaminating the valves that control the flow of fluid.
摘要翻译：一种药物输送装置，其利用具有开关装置的流体子系统（26）将多种药物输送到动物而不会造成污染。流体子系统还可以包括一次性注射器，（12,14,16）流体储存器（34,36,38），一次性管（40,44,48）和导管。在利用多个一次性注射器（12,14,16）的实施例中，药物输送装置允许使用者通过导管将多种药物递送至动物，而不会污染控制该多个药物的开关装置（18,20,22,24）流体流动。药物输送装置可以进一步利用控制器来控制开关装置以及控制器和注射泵以控制注射器的操作。

2. 发明公开

EP3156794A4 METHOD FOR DILUTE PLASMA SEPARATION USING CONTAINER FOR BLOOD DILUTION AND STORAGE CONTAINING GELLING AGENT FOR PLASMA SEPARATION 审中-公开
公开(公告)号：EP3156794A4
公开(公告)日：2018-01-24
申请号：EP14894697
申请日：2014-06-12
申请人： LEISURE INC
发明人： SUGIMOTO SHINYA , YONEKUBO ISAO , KAWAGUCHI MASATO , OSAWA SUSUMU
IPC分类号： G01N33/49 , A61B10/00
CPC分类号： G01N1/38 , A61B5/14 , A61B10/0096 , B01D21/26 , B01L3/50215 , G01N1/20 , G01N33/48 , G01N33/491 , G01N2001/381
摘要： A method for separating plasma in a minute amount of a blood sample diluted with a blood dilution buffer is provided. When a blood dilution buffer is added to a minute amount of blood (about 20 to 100 µL) so as to assay the biological blood components in the resulting diluted plasma, it is necessary to separately store and transfer the diluted blood cell component and the diluted plasma component. The present inventors found that it is possible to separate diluted plasma from diluted blood cells using a polymer gelling agent for plasma separation by means of putting a polymer gel for plasma separation in the container with a blood dilution buffer. In such case, diluted blood cells are transferred to the lower portion of the polymer gelling agent and dilute plasma is transferred to the upper portion of the same. Assay of the biological blood components using a minute amount of blood can be utilized for early detection of health status, diseases, and presymptomatic states. The method is advantageous in that it is not limited in terms of time or location for blood collection.

3. 发明公开

EP2305446A1 Multilayer containers and process for forming multilayer containers 审中-公开
标题翻译：多层容器及其制造方法多层容器
公开(公告)号：EP2305446A1
公开(公告)日：2011-04-06
申请号：EP10185343.0
申请日：2002-06-14
申请人： Becton Dickinson and Company
发明人： Grippi, Nicholas A. , Soskey, Paul R. , Carano, Donald J. , Hutton, Norman J. , Desalvo, Danielle M. , Lusardi, Gregory L. , Ahern, Brian F.
IPC分类号： B29C45/16
CPC分类号： B29C45/1642 , A61B5/14 , A61B5/1438 , A61B5/15003 , A61B5/150274 , A61B5/150351 , A61B5/150755 , A61B5/154 , B01L3/5082 , B01L2200/12 , B01L2200/142 , B01L2300/10 , B01L2300/12 , B01L2300/16 , B29L2023/22 , B29L2031/712 , B29L2031/753 , Y10T428/1352
摘要： A co-injection process is provided for fabricating improved multi-layer containers, including but not limited to blood collection tubes, evacuated blood collection tubes, culture bottles, centrifuges tubes, and syringe barrels. The container includes a tube (10) having a bottom wall (12) and a side wall (14) with an open end (18). The container can be provided with a stopper having an upper portion (22) and a skirt with an outside portion (30), a well (34) and a cavity (36). The tube and stopper assembly can be used for medical purposes including containing a blood sample within an enclosed interior space (40).
摘要翻译：本发明提供一种共注射过程用于制造改进的多层容器，包括但不限于血液收集管，真空血液收集管，培养瓶，离心机管和注射器筒。该容器包括具有底壁（12）和一个侧壁（14）具有开口端（18）的管（10）。该容器可以设置有具有止动件上部（22）和与外侧部分（30）的裙部，阱（34）和一空腔（36）。在管和塞子组件可用于医疗目的，包括在封闭的内部空间（40）内包含的血液样品。

4. 发明公开

EP0193279A3 A vacuum blood-collection tube 无效
标题翻译：真空血液收集管
公开(公告)号：EP0193279A3
公开(公告)日：1988-06-01
申请号：EP86300574
申请日：1986-01-28
申请人： SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA
发明人： Anraku, Hideo , Shoji, Yoshikata
IPC分类号： A61B05/14 , B01L03/14
CPC分类号： B01L3/5082 , A61L31/10 , A61B5/14
摘要： A vacuum blood-collection tube comprises a tube-shaped vessel having an opening through which air can be removed, and a plug that makes the opening air-tightto maintain low-pressure conditions inside the said vessel, the raw materials of the said vessel being polyethyleneterephthalate, a copolymer of polyethylene-terephthalate, or an acrylonitrile resin, and the inner walls of said vessel incorporating a hydrophilic substance that is either difficult or impossible to dissolve in water and that prevents blood clots from adhering to the inner walls of said tube, a water-soluble substance, and an adsorptive inorganic substance.

5. 发明授权

EP3781091B1 FLUID COLLECTION DEVICE 有权
公开(公告)号：EP3781091B1
公开(公告)日：2024-07-31
申请号：EP19789298.7
申请日：2019-04-17
IPC分类号： A61F5/453 , A61F5/44 , A61F5/451 , A61B5/15 , A61B5/145 , A61B10/00 , A61F5/443 , A61F5/445 , A61F5/455 , A61F5/449
CPC分类号： A61B10/007 , A61B10/0038 , A61B2010/00820130101 , A61B10/0045 , A61B5/150045 , A61B5/150221 , A61B5/150366 , A61B5/14 , A61B5/150992 , A61F5/4404 , A61F5/453 , A61F5/455 , A61F5/449 , A61F5/445 , A61F5/443 , A61F5/4405 , A61F5/4408 , A61F5/44

6. 发明公开

EP3156794A1 METHOD FOR DILUTE PLASMA SEPARATION USING CONTAINER FOR BLOOD DILUTION AND STORAGE CONTAINING GELLING AGENT FOR PLASMA SEPARATION 审中-公开
标题翻译：稀释血浆分离包血液稀释剂和存储与胶凝用于血浆分离方法
公开(公告)号：EP3156794A1
公开(公告)日：2017-04-19
申请号：EP14894697.3
申请日：2014-06-12
申请人： Leisure, Inc.
发明人： SUGIMOTO Shinya , YONEKUBO Isao , KAWAGUCHI Masato , OSAWA Susumu
IPC分类号： G01N33/48
CPC分类号： G01N1/38 , A61B5/14 , A61B10/0096 , B01D21/26 , B01L3/50215 , G01N1/20 , G01N33/48 , G01N33/491 , G01N2001/381
摘要： A method for separating plasma in a minute amount of a blood sample diluted with a blood dilution buffer is provided. When a blood dilution buffer is added to a minute amount of blood (about 20 to 100 µL) so as to assay the biological blood components in the resulting diluted plasma, it is necessary to separately store and transfer the diluted blood cell component and the diluted plasma component. The present inventors found that it is possible to separate diluted plasma from diluted blood cells using a polymer gelling agent for plasma separation by means of putting a polymer gel for plasma separation in the container with a blood dilution buffer. In such case, diluted blood cells are transferred to the lower portion of the polymer gelling agent and dilute plasma is transferred to the upper portion of the same. Assay of the biological blood components using a minute amount of blood can be utilized for early detection of health status, diseases, and presymptomatic states. The method is advantageous in that it is not limited in terms of time or location for blood collection.
摘要翻译：提供了一种用于在具有血液稀释缓冲液稀释的血液样品的微量分离血浆的方法。当血液稀释缓冲液被添加到的血液（大约20至100微升）以测定所得到的稀释血浆中的生物血液成分的分钟量，有必要分别存储和传输的稀释血细胞成分和稀释血浆成分。本发明人发现这样做是有可能通过意味着把用于血浆分离的聚合物凝胶在容器中与血液稀释缓冲液以分离使用用于血浆分离的聚合物胶凝剂稀释稀释血细胞的血浆。在搜索的情况下，稀释的血细胞被转移到聚合物胶凝剂的下部，并稀释血浆转移到相同的上部。使用的血液微量生物的血液成分的测定法可用于早期检测的健康状况，疾病，症状发生前和状态。在这样做是不是在采血时间或位置方面受到限制的方法是有利的。

7. 发明授权

EP2503938B1 BANDMAGAZIN MIT RÜCKDREHSPERRE UND INTEGRIERTER BANDFREIGABE 有权
标题翻译：背部旋转锁定和集成胶带剥离带盒
公开(公告)号：EP2503938B1
公开(公告)日：2013-10-30
申请号：EP10787059.4
申请日：2010-11-23
申请人： Roche Diagnostics GmbH , F.Hoffmann-La Roche AG
发明人： KONYA, Ahmet , LIST, Hans , KUHR, Hans-Jürgen
IPC分类号： A61B5/155 , A61B5/151
CPC分类号： A61B5/1427 , A61B5/02035 , A61B5/14 , A61B5/1405 , A61B5/1411 , A61B5/150022 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150916 , A61B5/15115 , A61B5/15153 , A61B5/15169 , A61B5/15171 , A61B5/15176

8. 发明公开

EP2503938A1 BANDMAGAZIN MIT RÜCKDREHSPERRE UND INTEGRIERTER BANDFREIGABE 有权
标题翻译：背部旋转锁定和集成胶带剥离带盒
公开(公告)号：EP2503938A1
公开(公告)日：2012-10-03
申请号：EP10787059.4
申请日：2010-11-23
申请人： Roche Diagnostics GmbH , F.Hoffmann-La Roche AG
发明人： KONYA, Ahmet , LIST, Hans , KUHR, Hans-Jürgen
IPC分类号： A61B5/155 , A61B5/151
CPC分类号： A61B5/1427 , A61B5/02035 , A61B5/14 , A61B5/1405 , A61B5/1411 , A61B5/150022 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150916 , A61B5/15115 , A61B5/15153 , A61B5/15169 , A61B5/15171 , A61B5/15176
摘要： The invention relates to a magazine (110) for use in an analytical test device (112). The magazine (110) is designed as an interchangeable magazine (110). The magazine (110) comprises a plurality of analytical accessories (118) on a carrier ribbon (116). The analytical accessories (118) can be provided by means of the carrier ribbon (116) in at least one application position (128) of the magazine (110). The magazine (110) further comprises at least one good spool (120) for receiving areas of the carrier ribbon (116) having unused analytical accessories (118) and at least one bad spool (122) for receiving areas of the carrier ribbon (116) having used analytical accessories (118). The carrier ribbon (116) can be moved from the good spool (120) to the bad spool (122) in a winding direction (126). The magazine (110) comprises a backturn preventer (136) of the bad spool (122). The magazine (110) further comprises a ribbon release device (142) designed to provide a bad spool ribbon reserve for the carrier ribbon (116) on the side of the application position (128) facing the bad spool (122). The bad spool ribbon reserve preferably allows a stroke movement (134) of an analytical accessory (118) present in the application position (128).

9. 发明授权

EP0193279B1 A vacuum blood-collection tube 无效
标题翻译：真空血液收集管
公开(公告)号：EP0193279B1
公开(公告)日：1992-01-29
申请号：EP86300574.0
申请日：1986-01-28
申请人： SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA
发明人： Anraku, Hideo , Shoji, Yoshikata
IPC分类号： A61B5/14 , B01L3/14
CPC分类号： B01L3/5082 , A61L31/10 , A61B5/14

10. 发明公开

EP0193279A2 A vacuum blood-collection tube 无效
标题翻译：真空血液收集管。
公开(公告)号：EP0193279A2
公开(公告)日：1986-09-03
申请号：EP86300574.0
申请日：1986-01-28
申请人： SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA
发明人： Anraku, Hideo , Shoji, Yoshikata
IPC分类号： A61B5/14 , B01L3/14
CPC分类号： B01L3/5082 , A61L31/10 , A61B5/14
摘要： A vacuum blood-collection tube comprises a tube-shaped vessel having an opening through which air can be removed, and a plug that makes the opening air-tightto maintain low-pressure conditions inside the said vessel, the raw materials of the said vessel being polyethyleneterephthalate, a copolymer of polyethylene-terephthalate, or an acrylonitrile resin, and the inner walls of said vessel incorporating a hydrophilic substance that is either difficult or impossible to dissolve in water and that prevents blood clots from adhering to the inner walls of said tube, a water-soluble substance, and an adsorptive inorganic substance.

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