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    • 2. 发明公开
    • Apparatus for the gelatin coating of medicaments
    • Vorrichtung zur Beschichtung von Medikamenten mit Gelatine
    • EP1774855A1
    • 2007-04-18
    • EP06076984.1
    • 1998-07-01
    • BAYER CORPORATION
    • Brehaut, Jeffrey D.Hoover, LinnKucharski, ThomasReiter, Thomas C.Revelle, David J.Slater, Daniel A.Torres, Luis R.Vo, Patrick
    • A23G3/00B05C3/00A61J1/00B05D1/00B65B1/00F26B15/00B65G49/00B65D85/00
    • A23G7/0025A23G3/24A61J3/005B05B16/20B05C3/10B65D1/36Y10S53/90
    • A process and apparatus for the gelatin coating of medicaments including a conveyer system (100) to advance pallets (200) through a loading station (10), dipping station (20), dryer station (34), reorientation station (50) and unloading station (70). Medicaments to be coated are loaded into a pallet (200) at the loading station (10) and advanced to a first dipping station (20) where a vacuum is applied to secure the medicaments to the pallet. The pallet is inverted and a first portion of each of the medicaments is dipped into a coating. The pallet is then returned to its upright position, the vacuum removed, and the coating dried. The medicaments are then transferred from the first pallet (200) to a second pallet (102) by a reorientation mechanism (59) so a second portion of the medicaments are coated in a second dipping station (60). The medicaments are advanced through the dryer station (34) and then ejected from the second pallet into a container (70).
    • 一种用于药物明胶涂层的方法和装置,包括输送系统(100),其通过装载站(10),浸渍站(20),干燥站(34),重新定向站(50)和卸载 车站(70)。 待涂覆的药物装载在装载站(10)的托盘(200)中,并且前进到第一浸渍站(20),在该位置施加真空以将药剂固定在托盘上。 将托盘倒置,并将每种药物的第一部分浸入涂层中。 然后将托盘返回到其直立位置,除去真空,并将涂层干燥。 然后通过重新定向机构(59)将药物从第一托盘(200)转移到第二托盘(102),使得第二部分药物涂覆在第二浸渍站(60)中。 药物通过干燥站(34)前进,然后从第二托盘排出到容器(70)中。
    • 10. 发明公开
    • Method for double dipping gelatin coated caplets
    • Verfahren zum doppelten Eintauchenfürmit GelatineüberzogeneTabletten。
    • EP0319318A2
    • 1989-06-07
    • EP88311447.2
    • 1988-12-02
    • McNEIL-PPC, INC.
    • Berta, Norbert I.
    • A61J3/06
    • A23J3/06A23G3/24A61J3/005A61J3/06A61J3/10A61K9/2072A61K9/2873
    • A novel capsule-like medicament and method for producing such medicaments are disclosed. The method provides a procedure for coating solid cores, such as caplets (16), with a first gelatinous coating (304) on one end (110), and then with a second gelatinous coating (306) on the other end (104) which is thicker than the first, to simulate the interlocking halves of a hollow capsule. The second, thicker gelatinous coating (306) can be provided with a single gelatin coating from a bath (38) having a higher viscosity than the bath used to provide the first gelatinous coating (304). Alternatively, the second gelatinous coating (306) can be provided by double dipping to provide layers of gelatinous material or gelatin.
    • 公开了一种新颖的胶囊状药物及其制备方法。 该方法提供了用于在一端(110)上涂覆第一凝胶状涂层(304),然后在另一端(104)上的第二凝胶状涂层(306)上涂覆固体芯例如盖片(16)的方法, 比第一个更厚,以模拟中空胶囊的互锁半部。 可以从具有比用于提供第一凝胶状涂层(304)的浴的粘度高的浴(38)提供第二较厚的凝胶状涂层(306)的单一明胶涂层。 或者,可以通过双重浸渍提供第二凝胶状涂层(306)以提供凝胶状材料或明胶层。