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    • 1. 发明公开
    • BACK-ILLUMINATED IMAGER USING ULTRA-THIN SILICON ON INSULATOR SUBSTRATES
    • 使用超薄硅在绝缘基板上的背照明成像器
    • EP2281307A1
    • 2011-02-09
    • EP09767294.3
    • 2009-05-27
    • Sarnoff Corporation
    • ZHU, RuiLEVINE, Peter, AlanSWAIN, Pradyumna, KumarBHASKARAN, Mahalingam
    • H01L27/12
    • H01L21/76254H01L27/1464H01L27/14689
    • A method for fabricating a back-illuminated semiconductor imaging device on an ultra-thin semiconductor-on-insulator substrate (UTSOl) is disclosed. The UTSOI substrate is formed by providing a handle wafer comprising a mechanical substrate and an insulator layer substantially overlying the mechanical substrate. A donor wafer is provided. Hydrogen is implanted in the donor wafer to form a bubble layer. The donor wafer is doped with at least one dopant to form a doped layer proximal to the bubble layer. The handle wafer and the donor wafer are bonded between the insulator layer of the handle wafer and a surface of the donor wafer proximal to the doped layer to form a combined wafer having a portion substantially underlying the bubble layer. The portion, of the combined wafer substantially underlying the bubble layer is removed so as to expose a seed layer. An epitaxial layer is grown substantially overlying the seed layer, wherein at least one dopant diffuse into the epitaxial layer. At the completion of the growing of the epitaxial layer, there exists a net dopant concentration in the seed layer and the epitaxial layer which has maximum value at or near an interface between the seed layer and the insulator layer.
    • 公开了一种用于在超薄绝缘体上半导体衬底(UTSO1)上制造背照式半导体成像器件的方法。 UTSOI衬底通过提供包括机械衬底和基本上覆盖机械衬底的绝缘层的处理晶片而形成。 提供施主晶圆。 将氢注入施主晶片以形成气泡层。 供体晶片掺杂有至少一种掺杂剂以形成靠近泡层的掺杂层。 处理晶片和施主晶片结合在处理晶片的绝缘层和施主晶片的靠近掺杂层的表面之间,以形成具有基本位于气泡层下方的部分的组合晶片。 基本上位于气泡层下面的组合晶片的部分被去除,以暴露种子层。 生长基本上覆盖种子层的外延层,其中至少一种掺杂剂扩散到外延层中。 在生长外延层完成时,晶种层和外延层中存在净掺杂物浓度,其在晶种层和绝缘体层之间的界面处或附近具有最大值。
    • 3. 发明公开
    • Computational protein probing to identify binding sites
    • 计算蛋白质探测结合位点的鉴定
    • EP1912145A3
    • 2009-10-21
    • EP07075671.3
    • 2003-03-11
    • Sarnoff Corporation
    • Guarnieri, Frank
    • G06F19/00
    • G06F19/16
    • Provided is a computer implemented method of analyzing a macromolecule for potential binding sites, comprising: positioning an instance of a computer representation of an organic fragment at a plurality of potential binding sites of the macromolecule; selecting a value of B , wherein B = µ' / k T + In , where µ' is the excess chemical potential, k is Boltzmann's constant, T is the absolute temperature, and N > is the mean number of molecules of the organic fragment; repositioning the instances of the organic fragment until a minimized energy state is obtained; assessing, for each instance of the repositioned organic fragment, whether the repositioned organic fragment binds to the macromolecule at the associated potential binding site at the selected value of B ; deleting instances of the organic fragment that do not bind at the associated potential binding site at the selected value of B ; repeating these steps at a lesser value of B ; and outputting a list of undeleted instances of the organic fragment; provided that the organic fragment is not water.
    • 6. 发明公开
    • Computational protein probing to identify binding sites
    • Rechnerische蛋白 - Sondierung zum Identifizieren von Bindungsstellen
    • EP1912145A2
    • 2008-04-16
    • EP07075671.3
    • 2003-03-11
    • Sarnoff Corporation
    • Guarnieri, Frank
    • G06F19/00
    • G06F19/16
    • Provided is a computer implemented method of analyzing a macromolecule for potential binding sites, comprising: positioning an instance of a computer representation of an organic fragment at a plurality of potential binding sites of the macromolecule; selecting a value of B , wherein B = µ' / k T + In , where µ' is the excess chemical potential, k is Boltzmann's constant, T is the absolute temperature, and N > is the mean number of molecules of the organic fragment; repositioning the instances of the organic fragment until a minimized energy state is obtained; assessing, for each instance of the repositioned organic fragment, whether the repositioned organic fragment binds to the macromolecule at the associated potential binding site at the selected value of B ; deleting instances of the organic fragment that do not bind at the associated potential binding site at the selected value of B ; repeating these steps at a lesser value of B ; and outputting a list of undeleted instances of the organic fragment; provided that the organic fragment is not water.
    • 提供了一种用于分析潜在结合位点的大分子的计算机实施方法,包括:将有机片段的计算机表示的实例定位在大分子的多个潜在结合位点; 选择B的值,其中B =μ'/ k T + In ,其中μ'是过量化学势,k是玻尔兹曼常数,T是绝对温度,N是平均分子数 的有机片段; 重新定位有机片段的实例,直到获得最小的能量状态; 评估重新定位的有机片段的每个实例,重新定位的有机片段是否以选定的B值与相关联的电位结合位点处的大分子结合; 删除在所选择的B值处不结合相关联的电位结合位点的有机片段的实例; 以较小的B值重复这些步骤; 以及输出所述有机片段的未删除实例的列表; 条件是有机片段不是水。