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1. 发明公开

EP1929301A2 MULTI-DIRECTIONAL IMMUNOCHROMATOGRAPHIC ASSAYS 审中-公开
标题翻译：不结盟多重免疫层析测试程序
公开(公告)号：EP1929301A2
公开(公告)日：2008-06-11
申请号：EP06801770.6
申请日：2006-08-17
申请人： Response Biomedical Corporation
发明人： HARRIS, Paul, C. , RICHARDS, Brian, G.
IPC分类号： G01N33/558
CPC分类号： G01N33/558
摘要： Methods for quantitatively measuring the amount of one or more analyte(s) of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods involve providing a solid phase apparatus comprising a membrane having an application point, a sample capture zone, and a control capture zone, where the sample capture zone and the control capture zone are approximately equidistant from the application point; and providing a sample collection apparatus comprising one or more population(s) of analyte binding particles. In the assays, a fluid sample is introduced into the sample collection apparatus, and the resultant mixture is applied to the application point of the membrane. The fluid allows transport components of the assay by capillary action to and through the sample capture zone(s) and the control capture zone. The amount of each analyte of interest in the fluid sample is related (e.g., either directly or inversely) to a corrected particle amount, which can be determined, for example, as a ratio of the amount of particles in the corresponding sample capture zone and the amount of particles in the control capture zone.

2. 发明公开

EP2132571A1 COMPARATIVE MULTIPLE ANALYTE ASSAY 有权
标题翻译：具有多个分析物的比较试验
公开(公告)号：EP2132571A1
公开(公告)日：2009-12-16
申请号：EP08725656.6
申请日：2008-02-15
申请人： Response Biomedical Corporation
发明人： HARRIS, Paul, C.
IPC分类号： G01N33/558 , G01N33/543
CPC分类号： G01N33/54313 , G01N33/54366 , G01N33/558 , Y10S435/81 , Y10S435/97 , Y10S435/975 , Y10S436/808 , Y10S436/81
摘要： Methods for measuring the relative amount of two or more analytes of interest in a fluid sample, as well as kits useful in the methods, are disclosed. The methods involve assays that utilize a solid phase apparatus with a membrane having an application point and at least two sample capture zones having sample capture reagents; analyte binding particles or analyte coated particles; and assessment of a ratio of such particles arrested in capture zones, wherein the ratio is equal to, or inversely equal to, the relative amounts of the analytes of interest in the fluid sample.

3. 发明授权

EP2132571B1 COMPARATIVE MULTIPLE ANALYTE ASSAY 有权
标题翻译：具有多个分析物的比较试验
公开(公告)号：EP2132571B1
公开(公告)日：2014-09-03
申请号：EP08725656.6
申请日：2008-02-15
申请人： Response Biomedical Corporation
发明人： HARRIS, Paul, C.
IPC分类号： G01N33/558 , G01N33/543
CPC分类号： G01N33/54313 , G01N33/54366 , G01N33/558 , Y10S435/81 , Y10S435/97 , Y10S435/975 , Y10S436/808 , Y10S436/81

4. 发明公开

EP2095124A1 MULTIPLE ANALYTE IMMUNOASSAY 无效转让
标题翻译：具有多分析物免疫
公开(公告)号：EP2095124A1
公开(公告)日：2009-09-02
申请号：EP07867698.8
申请日：2007-12-11
申请人： Response Biomedical Corporation
发明人： FONG, Whalley K. , HARRIS, Paul C. , RICHARDS, Brian G.
IPC分类号： G01N33/543 , G01N33/558
CPC分类号： G01N33/558 , G01N33/54313
摘要： Methods for measuring the amount of two or more analytes of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods involve determining a ratio of a detected amount of a single analyte of interest, to the sum of a detected amount of each of the analytes of interest plus a detected amount of a control, wherein the amount of each analyte of interest is directly or inversely related to the ratio for each analyte of interest.

5. 发明授权

EP2095124B1 MULTIPLE ANALYTE IMMUNOASSAY 无效转让
标题翻译：具有多分析物免疫
公开(公告)号：EP2095124B1
公开(公告)日：2010-10-20
申请号：EP07867698.8
申请日：2007-12-11
申请人： Response Biomedical Corporation
发明人： FONG, Whalley K. , HARRIS, Paul C. , RICHARDS, Brian G.
IPC分类号： G01N33/543 , G01N33/558
CPC分类号： G01N33/558 , G01N33/54313

6. 发明授权

EP1493029B1 SENSITIVE IMMUNOCHROMATOGRAPHIC ASSAY 有权转让
标题翻译：敏感性免疫印迹测定
公开(公告)号：EP1493029B1
公开(公告)日：2010-03-31
申请号：EP03711770.2
申请日：2003-04-10
申请人： Response Biomedical Corporation
发明人： FONG, Whalley, K.
IPC分类号： G01N33/543 , G01N33/558
CPC分类号： G01N33/54386 , G01N33/54313 , G01N33/558 , Y10S435/805 , Y10S435/81 , Y10S435/97

7. 发明公开

EP2130028A1 MODULAR ASSAY READER SYSTEM AND APPARATUS 审中-公开
标题翻译：模块化测试读卡系统和设备
公开(公告)号：EP2130028A1
公开(公告)日：2009-12-09
申请号：EP08726984.1
申请日：2008-03-19
申请人： Response Biomedical Corporation
发明人： HARRIS, Paul C.
IPC分类号： G01N21/64 , A61B5/00
CPC分类号： G01N35/00584 , G01N35/00871 , G01N2035/00851
摘要： A modular reader system and method provides for testing a test sample and determining characteristics of the sample. A first test module is configured to perform a first reading on a test sample and produce data regarding the reading. A second test module is configured to perform a second reading of the test sample and produce data regarding the second reading. The first and second test modules are communicatively coupled to a control module. The control module collects the data produced by the first and second test modules and processes the data to determine characteristics of the test sample.

8. 发明公开

EP2095125A2 SYSTEMS AND METHODS FOR PREPARING AND ANALYZING SAMPLES 审中-公开
标题翻译：系统和制备方法及其样本的分析
公开(公告)号：EP2095125A2
公开(公告)日：2009-09-02
申请号：EP07874303.6
申请日：2007-11-20
申请人： 3M Innovative Properties Company , Response Biomedical Corporation
发明人： MACH, Patrick A. , CLONEY, Lynn P. , GUO, Chunmei , HARRIS, Paul C. , KATZENMAIER, Kevin R. , KINNAIRD, Barbara R. , REIF-WENNER, Mara S. , ROSAUER, Michelle L. , SMITH, Jeffrey D. , WEBB, Heather M.
IPC分类号： G01N33/569 , G01N33/577 , G01N33/542 , G01N33/02
CPC分类号： G01N33/56911 , G01N1/38 , G01N33/558 , G01N33/56938
摘要： The invention relates to systems and methods for preparing and analyzing samples (e.g., mucosal samples) for a microorganism of interest. In particular, the systems and methods are useful for detecting one or more analytes characteristic of a microorganism (i.e., microbe) of interest, such as components of cell walls that are characteristic of a microbe, particularly Staphylococcus aureus.

9. 发明公开

EP1493029A2 SENSITIVE IMMUNOCHROMATOGRAPHIC ASSAY 有权转让
标题翻译：灵敏的免疫色谱分析
公开(公告)号：EP1493029A2
公开(公告)日：2005-01-05
申请号：EP03711770.2
申请日：2003-04-10
申请人： Response Biomedical Corp.
发明人： FONG, Whalley, K.
IPC分类号： G01N33/543 , G01N33/558
CPC分类号： G01N33/54386 , G01N33/54313 , G01N33/558 , Y10S435/805 , Y10S435/81 , Y10S435/97
摘要： Methods for quantitatively measuring the amount of an analyte of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods involve providing a solid phase apparatus comprising a membrane having an application point, a sample capture zone, and a control capture zone, where the sample capture region is between the contact region and the control capture zone; and providing a sample collection apparatus comprising a population of analyte binding particles or a population of analyte coated particles. In the assays, a fluid sample is introduced into the sample collection apparatus, and the resultant mixture is applied to the application point of the membrane. The fluid allows transport components of the assay by capillary action to and through the sample capture zone and subsequently to and through the control capture zone. The amount of analyte in the fluid sample is related (e.g., either directly or inversely) to a corrected particle amount, which can be determined, for example, as a ratio of the amount of particles in the sample capture zone and the amount of particles in the control capture zone.
摘要翻译：用于定量测量流体样品中感兴趣分析物的量的方法以及在所述方法中有用的试剂盒被公开。该方法包括提供包含膜的固相装置，所述膜具有施用点，样品捕获区和对照捕获区，其中样品捕获区在接触区和对照捕获区之间; 并提供包含分析物结合颗粒群或分析物涂覆颗粒群的样品收集装置。在测定中，将流体样品引入到样品收集装置中，并将所得混合物施加到膜的施加点。流体通过毛细管作用允许测定的转运组分通过和通过样品捕获区并且随后通过和通过对照捕获区。流体样品中的分析物的量与校正的颗粒量相关（例如，直接或相反），其可以例如确定为样品捕获区中颗粒的量与颗粒的量之比在控制捕获区域。

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