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    • 7. 发明公开
    • COMPOSITION COMPRISING HERBAL EXTRACTS OR FERMENTED PRODUCTS THEREOF HAVING LACTIC ACID BACTERIA FOR PREVENTING OR TREATING RESPIRATORY DISEASES
    • 配合中药提取物及产品组合物以及用于预防乳酸菌和呼吸系统疾病的治疗有发酵
    • EP2716295A2
    • 2014-04-09
    • EP12792329.0
    • 2012-05-30
    • Korea Institute of Oriental Medicine
    • MA, Jin YeulKIM, Dong SeonYANG, Min CheolYOON, Jong Hyun
    • A61K36/489A61K36/484A61K36/355A61P11/00
    • A61K36/725A61K35/744A61K36/185A61K36/23A61K36/232A61K36/25A61K36/28A61K36/355A61K36/484A61K36/489A61K36/634A61K36/704A61K36/78A61K2236/19A61K2300/00
    • The present invention relates to a composition for preventing or treating respiratory diseases, and more particularly, to a pharmaceutical composition, and to a health food, comprising extracts of herbal mixtures or fermented products thereof having lactic acid bacteria as effective ingredients for preventing or treating respiratory diseases, wherein the herbal mixtures comprise: Sophora flavascens, Radix glycyrrhizae, Flos Lonicerae, Angelicae Gigantis radix, Aralia continentalis, Inula helenium, Saposhnikoviae radix, Zizyphus spinosa, Houttuynia cordata, Forsythiae fructus, Arctium lappa, Herba epimedii, ginseng, Lithospermi radix, Sanguisorbae radix, Cnidii rhizoma, Scrophulariae radix, and Polygoni cuspidati radix. The herbal extracts or fermented products thereof having lactic acid bacteria exhibit the effects of significantly lowering an airway resistance value; reducing the numbers of leukocytes, neutrophilic leukocytes, lymphocytes, eosinocytes, and basophil leukocytes to levels similar to that of a normal group; and reducing the infiltration of inflammatory cells and eosinocyte cells near AHR on lung tissues. Therefore, the herbal extracts or fermented products thereof having lactic acid bacteria may be valuably used for the prevention and/or treatment of respiratory diseases such as asthma.
    • 本发明涉及一种组合物,用于预防或治疗呼吸疾病,并且更具体地,涉及一种药物组合物,以及一种健康食品,其包含混合草药或发酵产物的提取物具有乳酸菌用于预防或治疗呼吸作为有效成分 疾病,worin草药混合物包含:苦参flavascens,甘草基数金银花,当归Gigantis,长白楤木,土木香,防风基数,刺枣树,蕺,连翘,牛蒡牛蒡子,淫羊藿人参,紫草基数, 地榆,川芎根茎玄参麦冬,和虎杖基数。 所述草药提取物或发酵产物及其具有乳酸菌表现出显着降低的气道阻力值的影响; 减少白细胞,嗜中性白细胞,淋巴细胞,嗜酸性,嗜碱细胞和白细胞的数量,以类似于正常水平做一组; 和减少炎症细胞和细胞浸润于肺组织AHR附近嗜酸球。 因此,草药提取物或发酵产物及其具有乳酸菌可有价值地用于治疗呼吸疾病的预防和/或治疗:如哮喘。