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    • 2. 发明公开
    • BIOMARKERS FOR EARLY DETERMINATION OF A CRITICAL OR LIFE THREATENING RESPONSE TO ILLNESS AND/OR TREATMENT RESPONSE
    • BIOMARKER ZURFRÜHERKENNUNGEINER KRITISCHEN ODERLEBENSGEFÄHRDENDENREAKTION AUF EINE KRANKHEIT UND / ODER AUF EINE BEHANDLUNG
    • EP3042200A4
    • 2017-07-12
    • EP14842541
    • 2014-09-05
    • FIO CORP
    • KAIN KEVINLILES W CONRADERDMAN LAURACONROY ANDREA
    • G01N33/543C40B30/04C40B40/10G01N33/48G01N33/68
    • G01N33/6842G01N2800/50G01N2800/52
    • The invention relates to the use of novel biomarkers and biomarker combinations having utility in the early determination of an individual's critical and/or life threatening response to illness and/or in predicting outcome of said illness. The measurement of expression levels of the products of the biomarkers and combinations of biomarkers of the invention have utility in making the determination of an individual's critical and/or life threatening response to illness. In some embodiments, the biomarker and biomarker combinations are agnostic and are independent of the pre-identification and/or determination of the cause or nature of the illness. In some embodiments, the biomarkers and biomarker combinations can be utilized to select treatment and/or monitor the effectiveness of treatment interventions for an individual who has a critical illness.
    • 本发明涉及新型生物标志物和生物标志物组合的应用,其用于早期确定个体对疾病的危急和/或危及生命的反应和/或预测所述疾病的结果。 本发明的生物标志物和生物标志物组合的产物表达水平的测量可用于确定个体对疾病的危急和/或危及生命的反应。 在一些实施方案中,生物标志物和生物标志物组合是不可知的并且独立于疾病的原因或性质的预先识别和/或确定。 在一些实施方案中,生物标志物和生物标志物组合可用于选择治疗和/或监测治疗干预对患有严重疾病的个体的有效性。