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    • 10. 发明公开
    • STERILIZATION OF TOPICAL ANTISEPTIC SOLUTIONS
    • STERILIZATION VON TOPISCHEN ANTISEPTISCHENLÖSUNGEN
    • EP3092013A4
    • 2017-06-21
    • EP15735217
    • 2015-01-07
    • CAREFUSION 2200 INC
    • DEGALA SATISHMCGINLEY CHRISTOPHER MATTHEWTHURMOND KENNETH BRUCE
    • A61L2/04A01N43/40A01N47/44A61L2/00A61P31/02C10N30/16
    • A61L2/0023A01N43/40A01N47/44A01N25/02A01N31/02
    • A method for sterilizing an antiseptic solution includes providing a container containing the antiseptic solution, the antiseptic solution having an initial purity, selecting a sterilization temperature from about 85° C. to about 135° C. and an sterilization time from about 1 minute to about 19 hours, heating the antiseptic solution to the selected sterilization temperature, maintaining the temperature for the selected sterilization time, and terminating the heating of the antiseptic solution when the sterilization time expires. After terminating the heating, the antiseptic solution has a post-sterilization purity. The sterilization temperature and the sterilization time are selected such that after terminating the heating, the antiseptic solution is sterile and has a post-sterilization purity of at least about 92% and the percentage point change in purity from the initial purity to the post-sterilization purity is at most about 5%.
    • 用于消毒抗菌溶液的方法包括提供含有抗菌溶液的容器,抗菌溶液具有初始纯度,选择约85℃至约135℃的灭菌温度和约1分钟至约 19小时,将杀菌剂溶液加热至选定的杀菌温度,将温度保持在选定的杀菌时间,并在灭菌时间结束时终止杀菌剂溶液的加热。 终止加热后,杀菌剂溶液具有杀菌后的纯度。 灭菌温度和灭菌时间被选择为使得在终止加热之后,消毒剂溶液是无菌的并且具有至少约92%的消毒后纯度,并且纯度从初始纯度到消毒后的百分点变化 纯度至多约5%。