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1. 发明授权

EP1666907B1 NMR spectrometer with flowthrough sample container 有权
公开(公告)号：EP1666907B1
公开(公告)日：2017-08-02
申请号：EP05023634.8
申请日：2005-10-28
申请人： Bruker Biospin Corp.
发明人： Rindlisbacher, Martin , Maas, Werner E.
IPC分类号： G01R33/30
CPC分类号： G01R33/307

2. 发明公开

EP2760339A4 FRAME-SEQUENTIAL MULTIWAVELENGTH IMAGING SYSTEM AND METHOD 审中-公开
标题翻译：帧序列更多波长成像系统和方法
公开(公告)号：EP2760339A4
公开(公告)日：2015-07-08
申请号：EP12836684
申请日：2012-09-27
申请人： BRUKER BIOSPIN CORP
发明人： FEKE GILBERT D
IPC分类号： A61B5/06 , A61B1/05 , A61B5/00 , A61B5/026 , A61B5/145 , A61B5/1455
CPC分类号： H04N5/33 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B5/0046 , A61B5/0059 , A61B5/0073 , A61B5/06 , A61B5/14551 , A61B2505/05 , F04C2270/041 , H04N7/18 , H04N13/0239
摘要： A frame-sequential multiwavelength imaging system comprises a wavelength switching device for producing a repeated series of different wavelength profiles, a detector for detecting the dynamic scene and a signal processing unit for synthesizing a dynamic multiwavelength image of the dynamic scene. The signal processing unit may comprise at least one input device at least one logic device and at least one output device. The system can be used in a method to perform multiwavelength imaging of a dynamic scene, typically for surgical purposes.

3. 发明公开

EP2508909A2 Method and apparatus for automated raw material screening 有权转让
标题翻译： Verfahren und Vorrichtung zur automatisierten Rohmaterialuntersuchung
公开(公告)号：EP2508909A2
公开(公告)日：2012-10-10
申请号：EP12163086.7
申请日：2012-04-04
申请人： Bruker BioSpin Corporation
发明人： Colson, Kimberly L. , Hicks, Joshua M. , Fischer, Christian
IPC分类号： G01R33/46
CPC分类号： G01N24/08 , G01N24/085 , G01N24/088 , G01R33/4625 , G01R33/543
摘要： An automated screening device that performs standardized system suitability tests and evaluations and measures components of a submitted sample to assist in the quality control screening of raw materials, ingredients, pharmaceuticals, chemicals, polymers, food products, petroleum and many other materials. After determining the performance suitability of an NMR spectrometer, the system permits samples to be submitted for screening. An NMR spectrum of a sample is acquired and a qualitative analysis unit identifies at least one reference NMR spectrum corresponding a compound present in the sample and a quantitative analysis unit integrates relative signal intensity signals of the sample spectrum in regions of peak intensity in the one reference NMR spectrum and compares integration results to a number of atoms in each region in order to confirm identification of the compound.
摘要翻译：一种自动筛选装置，执行标准化系统适用性测试和评估并测量提交样品的组成部分，以协助对原材料，成分，药品，化学品，聚合物，食品，石油和许多其他材料进行质量控制筛选。在确定NMR光谱仪的性能适用性后，系统允许提交样品进行筛选。获得样品的NMR光谱，并且定性分析单元鉴定对应于样品中存在的化合物的至少一个参考NMR光谱，并且定量分析单元将样品光谱的相对信号强度信号在该参考的峰强度区域中积分 NMR谱，并将整合结果与每个区域中的多个原子进行比较，以确认化合物的鉴定。

4. 发明授权

EP1247114B1 SUPERCONDUCTIVE NETWORKS TO OPTIMIZE MULTIPLY TUNED NMR COILS 有权
标题翻译：超导网络以优化多重调谐NMR COIL
公开(公告)号：EP1247114B1
公开(公告)日：2008-02-06
申请号：EP01988870.0
申请日：2001-10-22
申请人： Varian, Inc. , Bruker Biospin Corp.
发明人： HILL, Howard, David, Wilson , FUKS, Luiz, Felipe
IPC分类号： G01R33/34
CPC分类号： G01R33/34 , G01R33/34023 , G01R33/34092 , G01R33/3635
摘要： A double tuned probe for employment in NMR apparatus includes a first resonant circuit of normal phase conductor coupled to the sample and also in communication with a second circuit containing a component in a superconductive phase. Communication between the two circuits supports two RF channels which may be exhibit relative sensitivities in proportion to their relative Q values.

5. 发明公开

EP1239297A2 Planar NMR coils with localized field-generating and capacitive elements 审中-公开
标题翻译：用于与所述局部场产生元件和电容元件的核自旋共振平面线圈
公开(公告)号：EP1239297A2
公开(公告)日：2002-09-11
申请号：EP02004049.9
申请日：2002-02-23
申请人： Bruker Biospin Corp.
发明人： Withers, Richard S.
IPC分类号： G01R33/34
CPC分类号： G01R33/341 , G01R33/34007 , G01R33/34023 , G01R33/34061 , G01R33/34092
摘要： Improved superconducting coils for a nuclear magnetic resonance probe use capacitive elements that are located in regions further from an active sample volume than magnetic field generating elements to which they are electrically connected. The sample volume is a substantially oblong shape, and the magnetic field generating elements run substantially parallel to the major axis of the shape, while the capacitor elements run perpendicular to the major axis. The magnetic field generating elements and the capacitor elements may vary in length relative to their distance from a center of the oblong shape. The total number of capacitors formed by the loops may vary from one embodiment to another, typically depending on the necessary resonant frequency. A coil may use sub-coils, each of which incorporates a plurality of the magnetic field generating elements and interdigital capacitor elements, the capacitor elements preferably being located to both sides of the oblong shape.
摘要翻译：用于核磁共振探头使用电容元件并位于有源另外的区域从样品体积比的磁场产生元件提高超导线圈与它们电连接。样品体积是基本长方形的形状，并且所述磁场产生元件大致平行的形状的主轴线，而电容器元件垂直运行于所述长轴。磁场产生元件和电容器元件可在相对于它们的距离长度从长圆形形状的中心变化。由环形成电容器的总数量可以从一个到另一个实施方式而变化，通常根据所需的谐振频率。线圈可以使用子线圈，其中的每一个结合了磁场产生元件和叉指式电容器元件的复数，所述电容器元件优选地位于该长形状的bothsides。

6. 发明公开

EP1953560A2 Nuclear magnetic resonance probe with cooled sample coil 审中-公开
标题翻译： Nukleare Magnetresonanzsonde mitgekühltemProbenkopf
公开(公告)号：EP1953560A2
公开(公告)日：2008-08-06
申请号：EP08001383.2
申请日：2008-01-25
申请人： Bruker Biospin Corp.
发明人： Lim, Yit Aun c/o LFK Corporation , Bez, Eckhard , Zhang, Xiaozhong , Maas, Werner E.
IPC分类号： G01R33/34 , G01R33/36
CPC分类号： G01R33/3628 , G01R33/34007 , G01R33/34015 , G01R33/34023 , G01R33/3403 , G01R33/34053 , G01R33/3635
摘要： In a nuclear magnetic resonance probe, the sample coil is connected to the RF excitation source via transmission lines that are arranged to generate one or more nodal points at the 1 H excitation frequency along their lengths and a balanced magnetic filed profile within the sample coil. Heat exchangers are then connected directly to the inner conductor of the transmission line at these nodal points. The transmission line inner conductors are in direct contact with the sample coil and efficiently cool the coil to cryogenic temperatures without interfering with the 1 H resonance or RF profile.
摘要翻译：在核磁共振探头中，采样线圈通过传输线路连接到RF激励源，传输线被布置成沿着它们的长度在1H激发频率处产生一个或多个节点，并且在采样线圈内产生平衡的磁场分布。然后，热交换器在这些节点处直接连接到传输线的内部导体。传输线内导体与样品线圈直接接触，并有效地将线圈冷却至低温，而不会干扰1H谐振或RF分布。

7. 发明公开

EP1574872A2 Planar NMR coil with gyromagnetic arc suppression 有权
标题翻译： Planare NMR RF-Spule mit gyromagnetischerUnterdrückungvonFunkendurchschlägen
公开(公告)号：EP1574872A2
公开(公告)日：2005-09-14
申请号：EP05004253.0
申请日：2005-02-26
申请人： Bruker Biospin Corp.
发明人： Withers, Richard S.
IPC分类号： G01R33/341
CPC分类号： G01R33/34053 , G01R33/34007 , G01R33/34023 , G01R33/34092 , G01R33/341
摘要： A magnetic resonance RF coil comprises a conductive material deposited on a dielectric substrate. The conductive material includes magnetic field generating elements used to generate an RF magnetic field and interdigital capacitor elements. The capacitor elements are oriented parallel to the magnetic field generating elements and, therefore, to a main static magnetic field within which the coil is to be located. This orientation minimizes arcing resulted from emitted electrons and helps to prevent catastrophic breakdown of the coil.
摘要翻译：磁共振RF线圈包括沉积在电介质基片上的导电材料。导电材料包括用于产生RF磁场和叉指电容器元件的磁场产生元件。电容器元件平行于磁场产生元件定向，并且因此定向到其中线圈将位于其中的主静态磁场。这种取向最小化由发射的电子产生的电弧，并有助于防止线圈的灾难性击穿。

8. 发明授权

EP2508909B1 Method and apparatus for automated raw material screening 有权转让
公开(公告)号：EP2508909B1
公开(公告)日：2021-06-02
申请号：EP12163086.7
申请日：2012-04-04
发明人： Colson, Kimberly L. , Hicks, Joshua M. , Fischer, Christian
IPC分类号： G01R33/46 , G01N24/08 , G01R33/54

9. 发明授权

EP1353193B1 Low-conductivity buffers for magnetic resonance measurements 有权
标题翻译：用磁共振测量低导电性缓冲
公开(公告)号：EP1353193B1
公开(公告)日：2008-12-03
申请号：EP03005384.7
申请日：2003-03-13
申请人： Bruker Biospin Corp. , The Regents of the University of California
发明人： Withers, Richard S. , Dötsch, Volker
IPC分类号： G01R33/46
CPC分类号： G01R33/46 , G01R33/465 , Y10T436/10 , Y10T436/108331 , Y10T436/24

10. 发明授权

EP1488247B1 FLOW-THROUGH CRYOGENIC NMR PROBE 有权
标题翻译：流过的低温NMR PROBE
公开(公告)号：EP1488247B1
公开(公告)日：2008-08-20
申请号：EP03744486.6
申请日：2003-03-13
申请人： Bruker Biospin Corp.
发明人： HOFMANN, Martin , SPRAUL, Manfred , NAST, Robert, Eric , HARRIS, Damon, Leslie
IPC分类号： G01R33/30
CPC分类号： G01R33/307 , G01R33/34023 , G01R33/34092
摘要： A nuclear magnetic resonance (NMR) spectroscopy probe has a sample cell into and out of which a room temperature liquid sample may be directed, The cell is surrounded by a radio frequency coil that is used to perform NMR measurements of the liquid sample, and which is maintained at cryogenic temperatures. The coil is separated from the sample cell by a thermally insulative boundary, such as a vacuum. The sample may enter the cell through an input path, and may exit through an output path. The input path, output path and sample cell may be surrounded by a sheath through which flows room temperature gas. The ends of the sample cell may be tapered to promote thorough flow through the cell, and flow diverters may be included in the sample cell adjacent to the input and output paths to force flow to the outer wall of the sample cell.

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