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1. 发明公开

EP3802496A1 VERFAHREN ZUR HERSTELLUNG VON SUBSTITUIERTEN N-ARYLPYRAZOLEN 无效转让
公开(公告)号：EP3802496A1
公开(公告)日：2021-04-14
申请号：EP19727945.8
申请日：2019-05-20
申请人： Bayer Aktiengesellschaft
发明人： REMBIAK, Andreas , MECHLER, Thomas , FORD, Mark James
IPC分类号： C07D231/12 , C07C243/28 , C07D307/20

2. 发明授权

EP3268353B1 PYRAZOLYL-DERIVATE ALS SCHÄDLINGSBEKÄMPFUNGSMITTEL 有权
公开(公告)号：EP3268353B1
公开(公告)日：2020-09-09
申请号：EP16708677.6
申请日：2016-03-09
申请人： Bayer Animal Health GmbH
发明人： SCHWARZ, Hans-Georg , MAUE, Michael , HALLENBACH, Werner , GÖRGENS, Ulrich , PORTZ, Daniela , ILG, Kerstin , KÖBBERLING, Johannes , TURBERG, Andreas
IPC分类号： C07D231/12 , C07D401/12 , C07D401/14 , C07D403/12 , C07D401/04 , C07D409/12 , A61P33/00 , A01N43/56 , A61K31/4439 , A61K31/415 , A61K31/506 , A61K31/4155

3. 发明公开

EP3578181A1 FORMULATION FOR USE IN THE SIMULTANEOUS TREATMENT OF COCCIDIAL INFECTIONS AND IRON DEFICIENCIES 审中-公开
公开(公告)号：EP3578181A1
公开(公告)日：2019-12-11
申请号：EP18176138.8
申请日：2018-06-05
申请人： Bayer Animal Health GmbH
发明人： The designation of the inventor has not yet been filed
IPC分类号： A61K31/53 , A61K45/06 , A61K9/00 , A61K31/555 , A23K50/60 , A23L33/10 , A23L33/165 , A61K47/60
摘要： The present invention relates to a formulation for use in the simultaneous treatment of coccidial infections and iron deficiencies containing a triazinone such as toltrazuril and a polynuclear iron(III) polysaccharide complex compound together with a specifically selected surfactant that has a hydrophilic-lipophilic-balance (HLB) value of ≥ 10.

4. 发明公开

EP3480195A1 METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES 审中-公开
公开(公告)号：EP3480195A1
公开(公告)日：2019-05-08
申请号：EP17200415.2
申请日：2017-11-07
申请人： Bayer Animal Health GmbH , The Kitasato Institute
发明人： The designation of the inventor has not yet been filed
IPC分类号： C07D413/14 , A01N43/72 , A61K38/15 , A61K45/06 , C07C269/06 , C07C271/22 , C07B51/00 , C07C231/12 , C07D273/00 , C07D273/08 , C07K11/02
摘要： The present invention relates to a method for the synthesis of cyclic depsipeptides, in particular emodepside, involving specific carboxylic acid group protecting tags:

TAG is preferably:

wherein m is ≥ 15 to ≤ 25, p is ≥ 8 to ≤ 18 and q is ≥ 15 to ≤ 25.

5. 发明授权

EP3177607B1 HALOGEN-SUBSTITUTED BIPYRAZOLE COMPOUNDS FOR CONTROLLING ANIMAL PESTS 有权转让
公开(公告)号：EP3177607B1
公开(公告)日：2018-09-26
申请号：EP15747158.2
申请日：2015-08-05
申请人： Bayer CropScience Aktiengesellschaft
发明人： MAUE, Michael , HARSCHNECK, Tobias , FISCHER, Reiner , HAHN, Julia Johanna , DÉCOR, Anne , HALLENBACH, Werner , SCHWARZ, Hans-Georg , KÖBBERLING, Johannes , HÜBSCH, Walter , BRETSCHNEIDER, Manfred Thomas
IPC分类号： C07D401/14 , C07D231/12 , C07D403/04 , A01N43/56
CPC分类号： C07D231/12 , A01N43/56 , A01N51/00 , C07D231/16 , C07D401/14 , C07D403/04
摘要： The invention relates inter alia to halogen-substituted compounds of the general formula (I) in which the substituents A1, R1-R3 and Z1-Z3 have the meanings given in the description. Also described are processes for preparing the compounds of the formula (I) and possible intermediates for the preparation of these compounds. The compounds according to the invention are particularly suitable for controlling insects, arachnids and nematodes in agriculture and ectoparasites in veterinary medicine.

6. 发明公开

EP3268353A1 PYRAZOLYL-DERIVATE ALS SCHÄDLINGSBEKÄMPFUNGSMITTEL 有权
标题翻译：吡唑啉衍生物作为杀虫剂
公开(公告)号：EP3268353A1
公开(公告)日：2018-01-17
申请号：EP16708677.6
申请日：2016-03-09
申请人： Bayer Animal Health GmbH
发明人： SCHWARZ, Hans-Georg , MAUE, Michael , HALLENBACH, Werner , GÖRGENS, Ulrich , PORTZ, Daniela , ILG, Kerstin , KÖBBERLING, Johannes , TURBERG, Andreas
IPC分类号： C07D231/12 , C07D401/12 , C07D401/14 , C07D403/12 , C07D401/04 , C07D409/12 , A61P33/00 , A01N43/56 , A61K31/4439 , A61K31/415 , A61K31/506 , A61K31/4155
摘要： The invention relates to novel pyrazolyl-derivatives of general formula (I). The invention also relates to methods for producing the compounds of formula (I). The compounds according to the invention are particularly suitable for controlling insects and arachnids in agricultural applications and for controlling ectoparasites in veterinary medicine.

7. 发明公开

EP3177607A1 NOVEL HALOGEN-SUBSTITUTED COMPOUNDS 有权转让
标题翻译：新型卤素取代的化合物
公开(公告)号：EP3177607A1
公开(公告)日：2017-06-14
申请号：EP15747158.2
申请日：2015-08-05
申请人： Bayer CropScience Aktiengesellschaft
发明人： MAUE, Michael , HARSCHNECK, Tobias , FISCHER, Reiner , HAHN, Julia Johanna , DÉCOR, Anne , HALLENBACH, Werner , SCHWARZ, Hans-Georg , KÖBBERLING, Johannes , HÜBSCH, Walter
IPC分类号： C07D401/14 , C07D231/12 , C07D403/04 , A01N43/56
CPC分类号： C07D231/12 , A01N43/56 , A01N51/00 , C07D231/16 , C07D401/14 , C07D403/04
摘要： The invention relates inter alia to halogen-substituted compounds of the general formula (I) in which the substituents A1, R1-R3 and Z1-Z3 have the meanings given in the description. Also described are processes for preparing the compounds of the formula (I) and possible intermediates for the preparation of these compounds. The compounds according to the invention are particularly suitable for controlling insects, arachnids and nematodes in agriculture and ectoparasites in veterinary medicine.
摘要翻译：本发明特别涉及通式（I）的卤素取代的化合物，其中取代基A1，R1-R3和Z1-Z3具有说明书中给出的含义。还描述了制备式（I）化合物的方法和用于制备这些化合物的可能的中间体。根据本发明的化合物特别适用于防治农业中的昆虫，蜘蛛和线虫以及兽药中的体外寄生虫。

8. 发明公开

EP3171925A1 TUBE MIT APPLIKATIONSSPITZE 有权转让
标题翻译：麻管MIT APPLIKATIONSSPITZE
公开(公告)号：EP3171925A1
公开(公告)日：2017-05-31
申请号：EP15738657.4
申请日：2015-07-17
申请人： Bayer Animal Health GmbH
发明人： HABIG, Jörg , HINXLAGE, Wilfried
IPC分类号： A61M31/00 , A61J1/00 , A61M35/00 , B65D35/00 , B65D1/09
摘要： The invention relates to a tube with an application tip (10) for a liquid or pasty medium, in particular medicinal product. The tube has a tube body (2) with an end (3) which can be closed or which is already closed and with an outlet end. The outlet end of the tube has a tube neck (5) with an outlet opening. The tube furthermore has an application tip (20) which is elongate in the longitudinal direction of the tube and which is connected to the outlet end of the tube and which has an inner duct which connects an inlet opening and an application opening. On the application opening of the application tip there is integrally formed a closure (24) which closes off the application opening. The application tip has a grip means (22).
摘要翻译：本发明涉及一种具有用于液体或糊状介质（特别是药用产品）的施用尖端（10）的管。该管具有一个管体（2），该管体具有一个可以关闭或已经关闭且具有一个出口端的端部（3）。管的出口端具有带出口的管颈（5）。管还具有应用尖端（20），其在管的纵向方向上是细长的并且连接到管的出口端并且具有连接入口开口和应用开口的内部管道。在施用尖端的施加开口处整体地形成封闭件（24），该封闭件封闭施用开口。施用尖端具有抓握装置（22）。

9. 发明公开

EP3083603A1 BENZIMIDAZOLDERIVATE ALS EP4-LIGANDEN 有权转让
公开(公告)号：EP3083603A1
公开(公告)日：2016-10-26
申请号：EP14814837.2
申请日：2014-12-16
申请人： Bayer Pharma Aktiengesellschaft
发明人： PETERS, Olaf , BRÄUER, Nico , BOTHE, Ulrich , KOPPITZ, Marcus , NAGEL, Jens , LANGER, Gernot
IPC分类号： C07D403/04 , A61K31/4184 , A61P5/00
CPC分类号： C07D403/04 , A61K45/06
摘要： The present invention relates to novel benzimidazole derivatives of the general formula (I), to methods for preparation thereof and to the use thereof for producing pharmaceutical compositions for treating disorders and indications associated with the EP4 receptor.
摘要翻译：本发明涉及通式（I）的新型苯并咪唑衍生物，其制备方法及其用于制备用于治疗与EP4受体相关的疾病和适应症的药物组合物。

10. 发明公开

EP3066080A1 SUBSTITUIERTE BENZAMIDE ZUR BEHANDLUNG VON ARTHROPODEN 有权转让
公开(公告)号：EP3066080A1
公开(公告)日：2016-09-14
申请号：EP14793179.4
申请日：2014-11-05
申请人： Bayer CropScience Aktiengesellschaft
发明人： HALLENBACH, Werner , SCHWARZ, Hans-Georg , ILG, Kerstin , GÖRGENS, Ulrich , KÖBBERLING, Johannes , TURBERG, Andreas , BÖHNKE, Niels , MAUE, Michael , VELTEN, Robert , HARSCHNECK, Tobias , HAHN, Julia Johanna , HORSTMANN, Sebastian
IPC分类号： C07D231/12 , A01N43/56 , A01N43/72 , C07D261/08 , A01P7/00 , C07D401/04 , C07D403/04 , C07D207/337 , A01N43/80
CPC分类号： C07D231/12 , A01N43/36 , A01N43/40 , A01N43/54 , A01N43/56 , A01N43/80 , C07D207/337 , C07D231/00 , C07D261/00 , C07D261/08 , C07D401/04 , C07D403/04 , C07D413/04
摘要： The invention relates, inter alia, to compounds of general formula (I), where the groups A
1 -A
4 , T, n, W, Q, R
1 and B
1 -B
4 have the meanings indicated in the description. Also described are methods for producing the compounds of formula (I). The compounds of the invention are particularly suitable for controlling insects, arachnids and nematodes in agriculture and ectoparasites in veterinary medicine.
摘要翻译：其中A1-A4，T，n，W，Q，R1和B1-B4基团各自如说明书中所定义。还描述了制备式（I）化合物的方法。本发明化合物特别适用于控制农业中的昆虫，蜘蛛和线虫，以及兽医学中的外寄生虫。

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