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1. 发明公开

EP3206629A1 LEAFLET-RESTRAINING TECHNIQUES 有权
标题翻译： LEAFLET-RESTRAINING技术
公开(公告)号：EP3206629A1
公开(公告)日：2017-08-23
申请号：EP15787691.3
申请日：2015-10-14
申请人： Valtech Cardio, Ltd.
发明人： GROSS, Amir , REICH, Tal , HERMAN, Yaron , IFLAH, Ehud , BRAUON, Haim , KUTZIK, Meir , IAMBERGER, Meni
IPC分类号： A61F2/24
CPC分类号： A61F2/2454 , A61B17/068 , A61B2017/00292 , A61B2017/0647 , A61B2017/0649 , A61F2/2445 , A61F2/2451 , A61F2/2457 , A61F2/2466 , A61F2220/0016
摘要： Apparatus, comprising: (i) a catheter (64); (ii) an implant (100), comprising a flexible longitudinal member (102), and a linking member (104) that extends from a first linking site (106a) of the longitudinal member to a second linking site (106b) of the longitudinal member, the implant having: (a) a delivery state in which the longitudinal member is coaxial with the catheter, and at least a portion of the linking member is disposed alongside the longitudinal member, and (b) an implanted state in which a first distance between the first linking site and the second linking site, measured along the longitudinal member, is greater than a second distance between the first linking site and the second linking site, measured along the linking member; and (iii) a plurality of tissue anchors (46), slidable through the catheter and with respect to the longitudinal member. Other embodiments are also described.
摘要翻译：装置，包括：（i）导管（64）; （ii）包括柔性纵向构件（102）和从纵向构件的第一连接点（106a）延伸到纵向连接点（106b）的第二连接点（106b）的连接构件（104）的植入物所述植入体具有：（a）所述纵向构件与所述导管同轴并且所述连结构件的至少一部分与所述纵向构件并排设置的输送状态，以及（b）植入状态，其中第一沿纵向构件测量的第一连接位置和第二连接位置之间的距离大于沿着连接构件测量的第一连接位置和第二连接位置之间的第二距离; 和（iii）多个组织锚定件（46），其可滑过所述导管并相对于所述纵向构件滑动。还描述了其他实施例。

2. 发明公开

EP3922213A1 LEAFLET-RESTRAINING TECHNIQUES 审中-实审转让
公开(公告)号：EP3922213A1
公开(公告)日：2021-12-15
申请号：EP21181923.0
申请日：2015-10-14
申请人： Valtech Cardio, Ltd.
发明人： GROSS, Amir , REICH, Tal , HERMAN, Yaron , IFLAH, Ehud , BRAUON, Haim , KUTZIK, Meir , IAMBERGER, Meni
IPC分类号： A61F2/24 , A61B17/068
摘要： An implant (240) for a native heart valve (10) of a heart (4) of a subject, the heart valve (10) having an annulus (16) defining an orifice between an atrium (6) and a ventricle (8), and a plurality of leaflets (12, 14), the implant (240) comprising:
a plurality of tissue anchors (46) configured to penetrate into tissue of the heart (4);
a support structure (242) configured to be anchored to an atrial side of the annulus by the plurality of tissue anchors (46); and
a resilient frame (244) configured to be secured to the support structure (242), the frame (244) having a constrained state for delivery to the heart valve (10) and an expanded state, wherein when in the expanded state, the frame (244) defines a leaflet-restraining portion (250) that (a) extends away from the support structure (242) and at least partway across the atrial side of the orifice of the heart valve (10) and (b) inhibits atrially-directed movement of a leaflet (14) of the heart valve (10), while allowing ventricularly-directed movement of the leaflet (14).

3. 发明公开

EP3848002A1 ADJUSTABLE ANNULOPLASTY DEVICES AND ADJUSTMENT MECHANISMS THEREFOR 审中-实审转让
公开(公告)号：EP3848002A1
公开(公告)日：2021-07-14
申请号：EP21153639.6
申请日：2009-12-22
申请人： Valtech Cardio, Ltd.
发明人： CABIRI, Oz , SHEPS, Tal , KUTZIK, Meir , GROSS, Amir , GROSS, Yossi , ZIPORY, Yuval
IPC分类号： A61F2/24 , A61B17/04
摘要： Apparatus is provided including an implant structure, a rotatable structure (2900) coupled to the implant structure in a vicinity of a first portion thereof, and a flexible member. The apparatus comprises a rotatable structure (2900) having a first end shaped to define a first opening, and a second end shaped to define a second opening, the rotatable structure being shaped to define a channel (48) extending from the first opening to the second opening, the channel being configured for passage therethrough of an elongate tool, and the second end of the structure having a lower surface (152) thereof shaped to define one or more recesses (154); and a mechanical element having a surface coupled to the lower surface of the rotatable structure, the mechanical element being shaped to provide: a protrusion (56) protruding out of a plane of the surface of the mechanical element, the protrusion being disposed within one of the recesses during a resting state of the mechanical element, in a manner that restricts rotation of the rotatable structure, anda depressible portion (28) coupled to the protrusion, the depressible portion being disposed in communication with the second opening of the lower surface, and configured to dislodge the protrusion from within the recess in response to a force applied thereto by the elongate tool.

4. 发明公开

EP2379008A2 ADJUSTABLE ANNULOPLASTY DEVICES AND ADJUSTMENT MECHANISMS THEREFOR 有权转让
标题翻译： EINSTELLBARE ANNULOPLASTIEVORRICHTUNGEN UND EINSTELLMECHANISMENDAFÜR
公开(公告)号：EP2379008A2
公开(公告)日：2011-10-26
申请号：EP09834225.6
申请日：2009-12-22
申请人： Valtech Cardio, Ltd.
发明人： CABIRI, Oz , SHEPS, Tal , KUTZIK, Meir , GROSS, Amir , GROSS, Yossi , ZIPORY, Yuval
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/0649 , A61B2017/12095 , A61F2/2442 , A61F2/2466 , A61F2250/0004 , A61F2250/001
摘要： Apparatus is provided including an implant structure (22, 122, 1122), a rotatable structure (2900) coupled to the implant structure (22, 122, 1122) in a vicinity of a first portion thereof, and a flexible member (30). At least a first portion of the 5 flexible member (30) is disposed in contact with the rotatable structure (2900), and at least one end portion of the flexible member (30) is not disposed in contact with the rotatable structure (30). In response to rotation of the rotatable structure (2900) in a first direction thereof, successive portions of the flexible member (30) contact the rotatable structure (2900) to pull the at least one end portion of the flexible member 0 (30) toward the first portion of the implant structure (22, 122, 1122), and responsively to draw the first and second portions of the implant structure (22, 122, 1122) toward each other. Other applications are also described.
摘要翻译：提供了包括植入结构（22,122,1122）的装置，在其第一部分附近与植入结构（22,122,1122）相连的可旋转结构（2900）和柔性构件（30）。所述柔性构件（30）的至少第一部分设置成与所述可旋转结构（2900）接触，并且所述柔性构件（30）的至少一个端部未设置成与所述可旋转结构（30）接触，。响应于可旋转结构（2900）沿其第一方向的旋转，柔性构件（30）的连续部分接触可旋转结构（2900）以将柔性构件0（30）的至少一个端部朝向植入结构（22,122,1122）的第一部分，并且响应地将植入物结构（22,122,1122）的第一和第二部分彼此拉出。还描述了其它应用。

5. 发明公开

EP3481335A1 ADJUSTABLE ANNULOPLASTY DEVICE WITH ALTERNATING PEAKS AND TROUGHS 有权转让
公开(公告)号：EP3481335A1
公开(公告)日：2019-05-15
申请号：EP17742562.6
申请日：2017-07-06
申请人： Valtech Cardio, Ltd.
发明人： KUTZIK, Meir , BRAUON, Haim , LEVIN, Michael , FOGEL, Alon , HARITON, Ilia , REICH, Tal
IPC分类号： A61F2/24

6. 发明公开

EP3288496A1 ANNULOPLASTY TECHNOLOGIES 有权转让
公开(公告)号：EP3288496A1
公开(公告)日：2018-03-07
申请号：EP16723535.7
申请日：2016-04-21
申请人： Valtech Cardio, Ltd.
发明人： IFLAH, Ehud , REICH, Tal , SHEPS, Tal , HARITON, Ilia , BRAUON, Haim , KUTZIK, Meir , KOIFMAN, Alexei , HERMAN, Yaron
IPC分类号： A61F2/24 , A61B17/04
CPC分类号： A61F2/2445 , A61B17/0401 , A61B17/068 , A61B2017/00323 , A61B2017/00477 , A61B2017/00783 , A61B2017/0409 , A61B2017/0441 , A61B2017/0446 , A61B2017/0496 , A61B2017/0649 , A61B2090/064 , A61B2090/3966 , A61F2/2412 , A61F2/2466 , A61F2250/0004 , A61F2250/001
摘要： Apparatus is provided including a percutaneously-implantable implant and an adjustment device. The adjustment device can comprise an adjustment mechanism, coupled to the implant, and configured to change a dimension of the implant upon actuation of the adjustment mechanism and a lock. The adjustment device can have a locked state in which the lock inhibits actuation of the adjustment mechanism and an unlocked state in which the adjustment mechanism is actuatable. The adjustment device can be reversibly movable between the locked state and the unlocked state. The apparatus can include a longitudinal guide member and an adapter. An unlocking mechanism can be configured such that, while the adapter is coupled to the adjustment device, actuation of the unlocking mechanism moves the lock between the locked state and the unlocked state. Other applications are also described.

8. 发明公开

EP3801390A1 IMPLANTABLE ANNULOPLASTY STRUCTURES TO FIT MULTIPLE ANNULUS SIZES 有权转让
公开(公告)号：EP3801390A1
公开(公告)日：2021-04-14
申请号：EP19728139.7
申请日：2019-05-21
申请人： Valtech Cardio, Ltd.
发明人： PELEG, Carmel , PEER, Amit , KUTZIK, Meir , FOGEL, Alon , AZOURI, Ben , BRAUON, Haim , CHAPPEL-RAM, Shlomit , REICH, Tal
IPC分类号： A61F2/24

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