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1. 发明公开

EP3608455A1 POROUS FIBER AND ADSORPTION COLUMN 有权
公开(公告)号：EP3608455A1
公开(公告)日：2020-02-12
申请号：EP18781532.9
申请日：2018-03-23
申请人： Toray Industries, Inc.
发明人： HAN, Aishan , FUJIEDA, Hiroaki , UENO, Yoshiyuki
IPC分类号： D01F6/00 , A61M1/36 , B01D15/00 , B01J20/20 , B01J20/28 , C01G23/047 , D01F6/52 , D01F8/10
摘要： The purpose of the present invention is to provide: a porous fiber that exhibits both improved adsorption capacity, and suppressed exposure and detachment of particulates; an adsorption column filled with said porous fiber; and a blood purification system in which an adsorption column is connected to a water removal column. In order to achieve this purpose, the porous fiber according to the present invention has the following constitution. Specifically, the porous fiber according to the present invention has a three-dimensional pore structure formed by a solid fiber, and satisfies all of the following conditions. (1) The porous fiber has particulates having a diameter of not more than 200 µm, and the perpcentage of area occupied by said particulates having a diameter of not more than 200 µm in a horizontal cross section of the three-dimensional pore structure is at least 3.0%. (2) The porous fiber does not contain said particulates having a diameter of not more than 200 µm in the region within 1.0 µm in the depth direction from the outermost surface.

2. 发明授权

EP3214210B1 POROUS POLYMER FIBERS FOR ADSORBENT MATERIAL 有权
公开(公告)号：EP3214210B1
公开(公告)日：2020-08-12
申请号：EP15856041.7
申请日：2015-10-20
申请人： Toray Industries, Inc.
发明人： FUJIEDA, Hiroaki , UENO, Yoshiyuki , TANAKA, Kazumi
IPC分类号： B01J20/28 , B01J20/26 , B01J20/30 , B01D15/20 , A61M1/36 , D01F6/00

3. 发明公开

EP3450596A1 POROUS FIBER, ABSORBING MATERIAL, AND PURIFYING COLUMN 审中-实审
公开(公告)号：EP3450596A1
公开(公告)日：2019-03-06
申请号：EP17789393.0
申请日：2017-04-20
申请人： Toray Industries, Inc.
发明人： FUJIEDA, Hiroaki , UENO, Yoshiyuki , TANAKA, Kazumi
IPC分类号： D01F6/00 , A61M1/36 , B01D15/00 , B01J20/26 , B01J20/28 , D01D5/253
摘要： A solid fiber having a modified cross-section which satisfies the following (a) to (b). (a) a modification degree Do/Di, in a cross section of the solid fiber, is 1.20 to 8.50 when the inscribed circle diameter is denoted by Di and the circumscribed circle diameter is denoted by Do; and (b) a porous specific surface area of the fiber is not less than 30 m 2 /g. An adsorbent material, comprising not less than 28 vol% of the above-mentioned porous fiber as a fiber bundle. A purification column which is formed by arranging the above-mentioned adsorbent material in the straight form in an axis direction of a plastic casing and by attaching an inlet port and an outlet port of a fluid that is to be treated to both ends of the plastic casing. Provided are a porous fiber which can efficiently adsorb a removal target substance in the fluid that is to be treated, and a purification column which incorporates the porous fiber.

4. 发明公开

EP2762180A1 PURIFICATION COLUMN AND METHOD FOR MANUFACTURING PURIFICATION COLUMN 审中-公开
标题翻译： VERFAHREN ZUR HERSTELLUNG DERREINIGUNGSSÄULE的REINIGUNGSSÄULE
公开(公告)号：EP2762180A1
公开(公告)日：2014-08-06
申请号：EP12834868.7
申请日：2012-09-26
申请人： Toray Industries, Inc.
发明人： FUJIEDA, Hiroaki , UENO, Yoshiyuki , TANAKA, Kazumi
IPC分类号： A61M1/36 , A61M1/18 , B01D63/00 , B01D63/02 , B01D69/08
CPC分类号： B01D63/021 , B01D63/022 , B01D2313/08 , B01D2313/40 , B01J20/28023 , B01J20/28038 , B01J2220/58
摘要： The present invention aims to provide a purification column having excellent performance to remove substances to be removed. Further, the present invention aims to provide a method for producing the purification column described above. The above object can be achieved with a purification column comprising a cylindrical casing having partition walls formed at both side ends, the casing containing therein hollow fibers whose both ends are fixed by bonding to the partition walls such that the both ends open to the outside of the partition walls, wherein penetrating holes that penetrate the partition walls to communicate with the inside and outside of the casing are formed in the partition walls at both ends of the casing.
摘要翻译：本发明的目的在于提供一种净化柱，其具有优异的除去待除去物质的性能。此外，本发明的目的在于提供一种上述纯化塔的制造方法。上述目的可以通过一种净化塔来实现，所述净化塔包括具有形成在两个侧端的分隔壁的圆柱形壳体，所述壳体包含中空纤维，所述中空纤维的两端通过结合到所述分隔壁而固定，使得所述两端通向分隔壁，其中穿过分隔壁以与壳体的内部和外部连通的穿透孔形成在壳体两端的分隔壁中。

5. 发明授权

EP2957306B1 BLOOD PURIFICATION COLUMN 有权
公开(公告)号：EP2957306B1
公开(公告)日：2019-01-02
申请号：EP14751732.0
申请日：2014-02-07
申请人： Toray Industries, Inc.
发明人： FUJIEDA, Hiroaki , UENO, Yoshiyuki , TANAKA, Kazumi
IPC分类号： A61M1/36 , B01J20/26 , B01J20/28

6. 发明公开

EP3214210A1 POROUS FIBERS, ADSORBENT MATERIAL, AND PURIFICATION COLUMN 有权
标题翻译：多孔纤维，吸附材料和净化柱
公开(公告)号：EP3214210A1
公开(公告)日：2017-09-06
申请号：EP15856041.7
申请日：2015-10-20
申请人： Toray Industries, Inc.
发明人： FUJIEDA, Hiroaki , UENO, Yoshiyuki , TANAKA, Kazumi
IPC分类号： D01F6/00 , B01J20/26 , B01J20/28
摘要： There are provided porous fibers having excellent removal performance with respect to a material to be purified; and a purification column into which an adsorbent material obtained by bundling the fibers is incorporated. The porous fibers satisfying the following conditions (a) and (b) and having a shape in which three or more projected parts are continuously present in the lengthwise direction on the periphery part of a solid-state fiber: (a) The modification degree Do/Di in a cross section is 1.2 to 6.6 when the diameter of the inscribed circle is denoted by Di and the diameter of the circumscribed circle is denoted by Do., and (b) The specific surface area of pores is 50 m 2 /g or more.
摘要翻译：提供了相对于待净化材料具有优异除去性能的多孔纤维; 以及将通过捆扎纤维获得的吸附材料并入其中的纯化塔。满足以下条件（a）和（b）并且具有在固态纤维的周边部分上沿长度方向连续存在三个或更多个突出部分的形状的多孔纤维：（a）修饰度Do / Di当内切圆的直径由Di表示并且外接圆的直径由Do表示时，截面中的/ Di为1.2至6.6，并且（b）孔的比表面积为50m 2 / g或更多。

7. 发明公开

EP4026573A1 FIBER BUNDLE, PRODUCTION METHOD FOR SAME, AND PURIFICATION COLUMN 审中-实审
公开(公告)号：EP4026573A1
公开(公告)日：2022-07-13
申请号：EP20874844.2
申请日：2020-10-07
申请人： Toray Industries, Inc.
发明人： OSUKA, Tomoaki , FUJIEDA, Hiroaki , UENO, Yoshiyuki , SAKAGUCHI, Hirokazu
IPC分类号： A61M1/16
摘要： An object of the present invention is to provide a purification column which is a small purification column in which a volume of a liquid to be treated is reduced in order to reduce the amount of blood to be taken out and which realizes a low pressure loss and has high adsorption performance. The present invention provides a fiber bundle including a plurality of porous fibers that satisfies the following requirements (A) to (E):
(A) the porous fiber has a non-hollow shape,
(B) an arithmetic average roughness (dry Ra value) of a surface of the porous fiber in a dry state is 11 nm or more and 30 nm or less,
(C) an arithmetic average roughness (wet Ra value) of a surface of the porous fiber in a wet state is 12 nm or more and 40 nm or less,
(D) a value represented by wet Ra/dry Ra is 1.05 or more, and
(E) a linear rate of the fiber bundle represented by (length of fiber bundle)/(length of one porous fiber) is 0.97 or more and 1.00 or less.

8. 发明公开

EP3738668A1 POROUS FIBERS, ADSORBENT MATERIAL, AND PURIFICATION COLUMN 审中-公开
公开(公告)号：EP3738668A1
公开(公告)日：2020-11-18
申请号：EP20183144.3
申请日：2015-10-20
申请人： Toray Industries, Inc.
发明人： FUJIEDA, Hiroaki , UENO, Yoshiyuki , TANAKA, Kazumi
IPC分类号： B01J20/28 , B01J20/26 , B01J20/30 , B01D15/20 , A61M1/36 , D01F6/00
摘要： There are provided porous fibers having excellent removal performance with respect to a material to be purified; and a purification column into which an adsorbent material obtained by bundling the fibers is incorporated. The porous fibers satisfying the following conditions (a) and (b) and having a shape in which three or more projected parts are continuously present in the lengthwise direction on the periphery part of a solid-state fiber: (a) The modification degree Do/Di in a cross section is 1.2 to 6.6 when the diameter of the inscribed circle is denoted by Di and the diameter of the circumscribed circle is denoted by Do., and (b) an index of pore shape Dxy is 0.2 or more and 6.0 or less.

9. 发明公开

EP3437671A1 FIBER MATERIAL AND PURIFICATION COLUMN 有权
公开(公告)号：EP3437671A1
公开(公告)日：2019-02-06
申请号：EP17775083.3
申请日：2017-03-28
申请人： Toray Industries, Inc.
发明人： FUJIEDA, Hiroaki , UENO, Yoshiyuki , YAMADA, Masayuki
IPC分类号： A61M1/36 , A61M1/34
摘要： The present invention is a fibrous material including fiber blends having plural types of solid fibers having a common cross-sectional shape,
wherein the composition ratio of each of at least two out of the plural types of fibers to the total of the fiber blends is not less than 5.0%, and when, among those plural types of fibers having a composition ratio of not less than 5.0%, fibers having the highest and the lowest surface area increase rates, which are given by the formula (1) below, are respectively designated as the fiber (max) and the fiber (min) , the surface area increase rate of the fiber (min) is reduced by 3.0% or more as compared to that of the fiber(max), and the composition ratios of the fiber (max) and the fiber (min) to the total of the fiber blends are not less than 30.0% and not less than 8.0%, respectively, and the fiber (max) has (a) a surface area increase rate of not less than 1.20 and is (b) a porous fiber with a micropore specific surface area of not less than 5 m 2 /g. Surface area increase rate = the circumference of a fiber cross section / the circumference of a circle having the same cross-sectional area as the fiber cross section
The present invention can provide a fibrous material made of fibers that enable efficient absorption of substances to be removed in a fluid that is to be treated, and a purification column incorporating the fibers.

10. 发明公开

EP2957306A1 BLOOD PURIFICATION COLUMN 有权
标题翻译： BLUTREINIGUNGSKOLONNE
公开(公告)号：EP2957306A1
公开(公告)日：2015-12-23
申请号：EP14751732.0
申请日：2014-02-07
申请人： Toray Industries, Inc.
发明人： FUJIEDA, Hiroaki , UENO, Yoshiyuki , TANAKA, Kazumi
IPC分类号： A61M1/36
CPC分类号： A61M1/3679 , A61M1/1006 , A61M1/14 , A61M1/36 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3652 , A61M1/3672 , A61M2205/75 , B01J20/26 , B01J20/261 , B01J20/262 , B01J20/28 , B01J20/28019 , B01J20/28023 , B01J20/2805
摘要： The present invention relates to a filter built into a blood purification column, and aims to dramatically improve the removal of air that gets into the column and to prevent blood activation due to air remaining inside of the column and decreased adsorption performance due to decreased contact surface between blood and an adsorbent. This blood purification column has an adsorbent and a casing, both ends of which are open ends, and the adsorbent is housed inside of the casing. Of the two ends of the casing, one is the blood inflow end and the other is the blood outflow end. A filter is arranged on the blood inflow end and/or the blood outflow end of the casing, and this filter fulfils the following conditions. (1) The opening ratio of the filter is 5-80% (2) The equivalent diameter of the openings in the filter is 1-5000µm (3) The ratio of the equivalent diameter of the openings to the average circle equivalent diameter of the gaps in the absorbent is 45% or greater.
摘要翻译：本发明涉及内置于血液净化塔中的过滤器，其目的在于显着改善进入柱内的空气的去除并防止由于残留在塔内部的空气引起的血液活化，并且由于接触表面减小而降低了吸附性能血液和吸附剂之间。该血液净化柱具有吸附剂和壳体，其两端为开口端，吸附剂容纳在壳体的内部。在套管的两端，一个是血液流入端，另一个是血液流出端。过滤器布置在壳体的血液流入端和/或血液流出端上，并且该过滤器满足以下条件。（1）过滤器的开口率为5-80％（2）过滤器开口的当量直径为1-5000μm（3）开口当量直径与平均圆当量直径的比值吸收剂中的间隙为45％以上。

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