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1. 发明公开

EP1661579A4 METHOD FOR TREATING DISEASES ASSOCIATED WITH CHANGES OF QUALITATIVE AND/ QUANTITATIVE COMPOSITION OF BLOOD EXTRACELLULAR DNA 失效转让
标题翻译： METHOD FOR疾病治疗用的质量和/或额外的细胞DNA定量组成变化相关
公开(公告)号：EP1661579A4
公开(公告)日：2009-11-25
申请号：EP04775224
申请日：2004-07-01
申请人： GENKIN DMITRY DMITRIEVICH , TETS VIKTOR VENIAMINOVICH
发明人： GENKIN DMITRY DMITRIEVICH , TETS VIKTOR VENIAMINOVICH , TETS GEORGY VIKTOROVICH
IPC分类号： A61K38/43 , A61K38/47 , A61K20060101 , A61K38/46 , A61K38/50 , A61P3/10 , A61P9/10 , A61P31/00
CPC分类号： A61K38/465 , C12Y301/21001

2. 发明公开

EP0896819A4 ANTIGLUCOCORTICOID DRUG 失效
标题翻译：药物基于抗糖皮质激素
公开(公告)号：EP0896819A4
公开(公告)日：2001-11-07
申请号：EP96902026
申请日：1996-02-01
申请人： BURLAKOV SERGEI DMITRIEVICH , GENKIN DMITRY DMITRIEVICH , SURKOV KIRILL GENNADIEVICH , TETS VIKTOR VENIAMINOVICH
发明人： BURLAKOV SERGEI DMITRIEVICH , GENKIN DMITRY DMITRIEVICH , SURKOV KIRILL GENNADIEVICH , TETS VIKTOR VENIAMINOVICH
IPC分类号： A61K31/045 , A61K31/075 , A61K31/08 , A61K31/11 , A61K31/22 , A61K31/235 , A61P5/38
CPC分类号： A61K31/235 , A61K31/045 , A61K31/22
摘要： The invention is related to medicine and veterinary fields, in particular to nonsteroidal antiglucocorticoids. An aim of the invention is the establishment of a new class of drugs with low toxicity and high activity in regulation of sensitivity of mammalian cells to the glucocorticoid hormones. There is a novel application of an insect pheromone with long-chain aliphatic nonsteroidal structure or its synthetic analog or derivative that is unsaturated aliphatic alcohol, aldehyde or ester, for specific inhibition of glucocorticoid hormone influence on mammalian cells. The aliphatic carbon chain length of these pheromones varies from 10 to 21 carbon atoms. There is also a possibility of combining application of two or more pheromones and/or their synthetic analogs and derivatives for enhancement of therapeutic activity, selection being made on the basis of different hydrophobic properties proportional to the aliphatic carbon chain length. Difference in lengths of these chains must be no less than five carbon atoms. Example of preparation of the pharmaceutical forms and results of comparative experiments that show their high activity are disclosed.

3. 发明公开

EP1666055A4 METHOD FOR TREATING ONCOLOGICAL, VIRULENT AND SOMATIC DISEASES, METHOD FOR CONTROLLING TREATMENT EFFICIENCY, PHARMACEUTICAL AGENTS AND COMPOSITION FOR CARRYING OUT SAID TREATMENT 审中-公开
标题翻译：方法用于治疗肿瘤，恶毒，躯体疾病，方法控制处理效率，药剂和组合物进行该处理的处理
公开(公告)号：EP1666055A4
公开(公告)日：2010-02-10
申请号：EP03796243
申请日：2003-07-14
申请人： TETS VIKTOR VENIAMINOVICH , GENKIN DMITRY DMITRIEVICH
发明人： TETS VIKTOR VENIAMINOVICH , GENKIN DMITRY DMITRIEVICH , TETS GEORGY VIKTOROVICH
IPC分类号： A61K38/43 , A61K31/7088 , A61K38/46 , A61K39/395 , A61M1/36 , A61P31/00 , A61P35/00 , G01N33/68
CPC分类号： C07K16/44 , A61K38/465 , A61K39/0011 , C12Y301/21001

4. 发明公开

EP2095825A4 METHOD FOR TREATING HUMAN DISEASES ASSOCIATED WITH AN INCREASED DEOXYRIBONUCLEIC ACID CONTENT IN EXTRACELLULAR SPACES OF TISSUES AND A MEDICINAL PREPARATION FOR CARRYING OUT SAID METHOD 有权转让
标题翻译：法人类在疾病连接的具有增加DESOXYRIBONUCLEINSÄUREGEHALT面料和医疗制剂的胞外区中的处理执行方法
公开(公告)号：EP2095825A4
公开(公告)日：2009-12-30
申请号：EP06843990
申请日：2006-11-28
申请人： GENKIN DMITRY DMITRIEVICH , TETS VIKTOR VENIAMINOVICH
发明人： GENKIN DMITRY DMITRIEVICH , TETS VIKTOR VENIAMINOVICH , TETS GEORGY VIKTOROVICH
IPC分类号： A61K38/47 , A61K9/02 , A61K9/20 , A61K9/48 , A61K9/68 , A61P43/00
CPC分类号： G06Q40/025 , A61K9/0031 , A61K9/0058 , A61K9/2018 , A61K9/2054 , A61K38/43 , A61K38/46 , A61K38/465 , A61K38/47 , C12Y301/21001 , G06F17/243 , G06Q40/02 , G06Q50/16 , H04L67/12

5. 发明公开

EP1655036A4 METHOD FOR TREATING ONCOLOGICAL DISEASES 失效转让
标题翻译： VERFAHREN ZUR BEHANDLUNG VON ONKOLOGISCHEN ERKRANKUNGEN
公开(公告)号：EP1655036A4
公开(公告)日：2009-06-17
申请号：EP04748955
申请日：2004-07-01
申请人： GENKIN DMITRY DMITRIEVICH , TETS VIKTOR VENIAMINOVICH
发明人： GENKIN DMITRY DMITRIEVICH , TETS VIKTOR VENIAMINOVICH , TETS GEORGY VIKTOROVICH
IPC分类号： A61K38/43 , A61K38/44 , A61K38/46 , A61K39/395 , A61P35/00
CPC分类号： A61K39/0011 , A61K38/465 , A61K38/48 , A61K2039/505 , A61K2039/53 , C07K16/44 , C12Y301/21001 , A61K2300/00
摘要： The invention relates to medicine and veterinary science and can be used for treating mainly solid tumors. The inventive method for treating oncological diseases consisting in injecting a blood extracellular DNA destroying agent into a systemic blood circulation. Said blood extracellular DNA destroying agent can be embodied in the form of a DNAse enzyme, in particular a bovine pancreatic DNAse which is parenterally injected in doses ranging from of 50 000 Kunz units to 250 000 000 Kunz units a day every day during 5-360 days or in the form of a recombinant human DNAse. In addition, a blood extracellular DNA binding agent embodied in the form of anti-DNA antibodies can be injected into a systemic blood circulation. In addition a modified agent which modifies the chemical composition and/or conformation and/or polymery and/or an association with proteins and/or lipids and/or ribonucleic acids of the blood extracellular DNA. Said modifying agent can be embodied in the form of a enzyme-ribonuclease. An extracellular ribonuclease of a Serratia Mercenses bacterium can be used in the form of said agents.
摘要翻译：本发明涉及医学和兽医学，可用于主要治疗实体瘤。本发明的治疗肿瘤疾病的方法包括将血细胞外DNA破坏剂注射到全身血液循环中。所述血细胞外DNA破坏剂可以以DNA酶的形式体现，特别是牛胰腺DNA酶，其在5-360天期间每天每天以50000Kunz单位至2500000000Kunz单位的剂量肠胃外注射天或以重组人DNAse的形式存在。此外，以抗DNA抗体形式体现的血细胞外DNA结合剂可以注射到全身血液循环中。另外还包括改变化学组成和/或构象和/或聚合和/或与血细胞外DNA的蛋白质和/或脂质和/或核糖核酸的缔合的修饰剂。所述修饰剂可以以酶 - 核糖核酸酶的形式体现。可以以所述药剂的形式使用粘质沙雷氏菌细菌的胞外核糖核酸酶。

6. 发明公开

EP2596794A4 METHOD FOR TREATING LIVER DISEASES OF VARIOUS ORIGINS 有权
标题翻译：方法肝病不同病因的治疗
公开(公告)号：EP2596794A4
公开(公告)日：2015-03-25
申请号：EP10797363
申请日：2010-06-04
申请人： TETS GEORGY VIKTOROVICH , TETS VIKTOR VENIAMINOVICH
发明人： TETS GEORGY VIKTOROVICH , TETS VIKTOR VENIAMINOVICH
IPC分类号： A61K31/515 , A61P1/16
CPC分类号： A61K31/515 , C07D239/66
摘要： The invention relates to medicine, in particular to gastroenterology, and lies in the field of treatment of liver diseases of various origins. For this purpose, the hepatoprotective agent that is introduced to the patient is embodied as derivatives of bis(2-thio-4,6-dioxo-1,2,3,4,5,6-hexahydropyrimidine-5-yl) arylmethanes. The method provides reduction of the manifestations of cytolysis under the influence of damaging agents and a statistically significant reduction of dysproteinemia, it accelerates restoration of detoxifying processes of the liver, increases induction of endogenic interferon alfa and, consequently, makes the protection of liver cells during hepatitides of various origins more effective.

7. 发明公开

EP2650285A4 FUNGICIDE 有权转让
标题翻译：杀菌剂
公开(公告)号：EP2650285A4
公开(公告)日：2014-07-09
申请号：EP11847307
申请日：2011-03-03
申请人： TETS VIKTOR VENIAMINOVICH , TETS GEORGY VIKTOROVICH , KRUTIKOV VIKTOR IOSIFOVICH
发明人： TETS VIKTOR VENIAMINOVICH , TETS GEORGY VIKTOROVICH , KRUTIKOV VIKTOR IOSIFOVICH
IPC分类号： C07D239/545 , A01N43/54 , A01P3/00 , A61K9/06 , A61K9/12 , A61K9/70 , A61P9/02 , A61P31/10
CPC分类号： A01N43/54 , C07D239/545
摘要： The invention relates to fungicides and can be used for treating diseases caused by fungi, and also for preventing damage to various materials and agricultural products by fungi. The fungicide is a 2,4-dioxo-5-(2- hydroxy-3,5-dichlorobenzylidiene)amino-1,3-pyrimidine salt of general formula: (A) or a dimer thereof: (B), where X is selected from the series consisting of: Na + , K + , Li + and NH 4 + . An effective preparation having anti-fungal activity with a broad spectrum of action is created.

8. 发明公开

EP3006020A4 METHOD FOR TREATING RECURRING SKIN AND MUCOUS MEMBRANE DISEASES CAUSED BY HSV-1 AND HSV-2 有权
标题翻译：方法用于治疗由HSV-1和HSV-2引起RECURRING皮肤和粘膜疾病
公开(公告)号：EP3006020A4
公开(公告)日：2017-02-15
申请号：EP14806838
申请日：2014-06-06
申请人： TETS VIKTOR VENIAMINOVICH , TETS GEORGY VIKTOROVICH
发明人： TETS VIKTOR VENIAMINOVICH , TETS GEORGY VIKTOROVICH
IPC分类号： A61K9/02 , A61K9/06 , A61K9/10 , A61K31/63 , A61P31/22
CPC分类号： A61K31/63 , A61K9/0014 , A61K9/0034 , A61K9/02 , A61K9/06 , A61K9/10
摘要： The invention relates to medicine and specifically to methods for treating recurring forms of diseases related to the family of herpes viruses. A method for treating recurring diseases of the skin and mucous membranes caused by HSV-1 and HSV-2 involves applying a preparation to an affected area, said preparation including a base containing 0.5% or 1% of an active substance, namely a (2,6-dichlorophenyl)amide salt of carbopentoxysulfanilic acid of general formula (I): where X is Na, K, NH 4 ; the preparation is applied twice daily for 3-5 days and, should prodromes appear, a second course of treatment is carried out, in which the preparation is applied 1-2 times daily for 2-3 days; the base containing the active substance can be in the form of a cream, an ointment, a gel, a suspension, suppositories, a patch or a film. Carrying out the second course of treatment provides a sharp increase in therapeutic efficacy, even to the extent of preventing relapse over a prolonged period of observation as a result of the effect of the preparation, upon reuse, on the viruses persisting in nerve cells.
摘要翻译：本发明涉及医学和专门用于处理有关家庭的疱疹病毒疾病的复发形式的方法。一种用于治疗皮肤的重复疾病和粘膜由HSV-1和HSV-2引起的方法包括在受影响的区域施加的制剂，该制剂包含含有0.5％或活性物质的1％时，基体即（2 ，6-二氯苯基）（I）通式carbopentoxysulfanilic酸的酰胺盐：其中X为Na，K，NH 4; 所述制剂3-5天每天施用两次，并且，shoulderstand前驱症状出现，治疗的第二过程中进行，其中所述制剂每天1-2次的应用2-3天; 含有活性物质的碱可以是乳膏，软膏，凝胶，悬浮液，栓剂，贴剂或膜的形式。进行处理的第二个疗程提供治疗功效的急剧增加，甚至防止复发整个观察长期作为制剂的效果的结果，在重复使用，对病毒在神经细胞中持续的程度。

9. 发明公开

EP3075840A4 DEVICE FOR DETERMINING THE SENSITIVITY OF MICROORGANISMS TO ANTIMICROBIAL DRUGS 有权转让
标题翻译： VERFAHREN ZUR BESTIMMUNG DER EMPFINDLICHKEIT VON MIKROORGANISMENGEGENÜBERANTIMIKROBIELLEN WIRKSTOFFEN
公开(公告)号：EP3075840A4
公开(公告)日：2017-05-31
申请号：EP14866121
申请日：2014-10-27
申请人： TETS VIKTOR VENIAMINOVICH , TETS GEORGY VIKTOROVICH
发明人： TETS VIKTOR VENIAMINOVICH , TETS GEORGY VIKTOROVICH
IPC分类号： C12M1/26 , C12Q1/06 , C12Q1/18
CPC分类号： C12Q1/18 , C12M23/12 , C12M41/34
摘要： The invention relates to the field of microbiology. A device for determining the sensitivity of microorganisms to antimicrobial drugs is configured in the form of a sterile plate made from a plastic material with indentations and is provided with a hermetically sealing element which covers the sterile plate. The indentations are filled with a solid culture medium containing agar. In different indentations, the culture medium contains antimicrobial drugs or combinations thereof or serves as a control. Between the plate and the hermetically sealing element, the device contains a moisture-absorbing material with a rigid mesh situated therebelow. The device is provided with a transparent protective lid made from a rigid durable plastic.
摘要翻译：本发明涉及微生物学领域。用于确定微生物对抗微生物药物的敏感性的装置以由具有压痕的塑料材料制成的无菌板的形式构成，并且设置有覆盖无菌板的密封元件。压痕填充有含琼脂的固体培养基。在不同的压痕中，培养基含有抗微生物药物或其组合，或用作对照。在板和密封元件之间，该装置包含位于其下方的具有刚性网的吸湿材料。该设备配有透明保护盖，由坚固耐用的塑料制成。

10. 发明公开

EP2918672A4 METHOD FOR DETERMINING THE SENSITIVITY OF MICROORGANISMS TO ANTIMICROBIAL SUBSTANCES 有权转让
标题翻译：用于确定免受微生物抗菌物质的敏感性
公开(公告)号：EP2918672A4
公开(公告)日：2016-07-06
申请号：EP13853343
申请日：2013-05-13
申请人： TETS VIKTOR VENIAMINOVICH , TETS GEORGY VIKTOROVICH
发明人： TETS VIKTOR VENIAMINOVICH , TETS GEORGY VIKTOROVICH
IPC分类号： C12N5/02 , C12Q1/18
CPC分类号： C12Q1/18
摘要： The invention relates to medicine and to veterinary medicine, and specifically to means for determining the sensitivity of various microorganisms, including bacteria and fungi, to antimicrobial substances. The method for determining the sensitivity of microorganisms to antimicrobial substances comprises taking biological material, incubating microorganisms contained therein on a nutrient medium, introducing an antimicrobial substance to be investigated into the nutrient medium and subsequently assessing the result. A dense, rich nutrient medium is used for cultivating the microorganisms. The antimicrobial substance being investigated is introduced into the nutrient medium prior to cultivation of the microorganisms in a concentration close to the maximum concentration achievable at the location at which the biological material is taken. The sensitivity of the microorganisms to the antimicrobial substance is assessed after the appearance of visible growth of microorganisms in a control culture. Vitamins and/or amino acids, and/or nutritional supplements can be added to the nutrient medium.

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