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1. 发明公开

EP2745808A1 INTRAVASCULAR STENT WITH IMPROVED VISUALIZATION PERFORMANCE AND METHOD FOR ENHANCING THE VISUALIZATION PERFORMANCE OF INTRAVASCULAR STENT 无效转让
标题翻译：以及用于改进性能的可视化血管内支架更好的性能可视化和方法血管内支架
公开(公告)号：EP2745808A1
公开(公告)日：2014-06-25
申请号：EP12823435.8
申请日：2012-08-15
申请人： Shanghai MicroPort Medical (Group) Co., Ltd.
发明人： WANAG, Sen , XIE, Zhiyong , LV, Jian , XU, Xiaohong , JIN, Qiaorong , LUO, Qiyi
IPC分类号： A61F2/82 , A61L31/18
CPC分类号： A61F2/88 , A61F2250/0098 , A61L31/18
摘要： An intravascular stent, especially an intracranial vascular stent, wherein a stent strut (1) of the stent is completely wound with at least one layer of wire (2) made from a visualizable material. The stent can ensure accurate positioning under medical imaging equipment during and after a surgery. In addition, since the wound visualizable wire (2) is located at a position on the stent subjected to little or no stress, the expansion and the stress distribution of the stent is not affected, so that the service life of the stent will not be shortened, nor will the expected effect of the stent in use be influenced. Also disclosed is a method for enhancing a visualization performance of an intravascular stent.
摘要翻译：血管内支架，爱特别是颅内血管支架，支架支杆worin（1）支架的完全呼叫卷绕有由一种材料制成可视化的金属丝（2）中的至少一个层。该支架可以在和手术后保证在医疗成像设备准确定位。另外，由于卷绕可视化的金属丝（2）位于上经受很小或没有应力，膨胀和支架的应力分布在支架的位置不受影响，所以没有支架的使用寿命也不会缩短，也不会支架在使用中的预期效果的影响。所以光盘游离缺失是提高血管内支架的性能可视化的方法。

2. 发明公开

EP2979649A1 INTRACRANIAL VASCULAR THROMBECTOMY DEVICE AND THROMBECTOMY APPARATUS 审中-公开
标题翻译：颅内血管切除装置和血栓切除装置
公开(公告)号：EP2979649A1
公开(公告)日：2016-02-03
申请号：EP14776485.6
申请日：2014-03-26
申请人： Shanghai MicroPort Medical (Group) Co., Ltd.
发明人： XU, Qingshun , NI, Zunzhang , XIE, Zhiyong , JIN, Qiaorong , JI, Jie , LIU, Cong , CHANG, Mengqi , LUO, Qiyi
IPC分类号： A61B17/22 , A61B17/32
CPC分类号： A61B17/221 , A61B2017/2212 , A61B2017/320064
摘要： A thrombus removal means (10) and a thrombus removal device (1) particularly suited to the removal of a thrombus from an intracranial vessel. The thrombus removal means (10) is a mesh structure defining a lumen and is switchable between a contracted configuration and an expanded configuration, the thrombus removal means (10) has inwardly and/or outwardly projecting features. The thrombus removal means (10) can hold a captured thrombus firmly during the retrieval, effectively trap plaques and clot fragments with an improved stiffness and with no possibility for them to dislodge therefrom, and can addresses the issue of distal re-embolization caused by the vessel wall plaques or clot fragments dislodging from the conventional thrombus removal devices by presenting an improved thrombus removal system with the additional benefit of a small profile and high flexibility.
摘要翻译：一种血栓清除装置（10）和血栓清除装置（1），特别适用于从颅内血管中清除血栓。血栓清除装置（10）是一个限定内腔的网状结构，可在收缩状态和扩张状态之间转换，血栓清除装置（10）具有向内和/或向外突出的特征。血栓清除装置（10）能够在取出过程中牢固地夹持捕获的血栓，有效地捕获具有改善的刚度并且不可能从中移出的斑块和凝块碎片，并且可以解决由血栓清除装置引起的远侧再栓塞问题通过提供改进的血栓清除系统使血管壁斑块或凝块碎片从传统的血栓清除装置中移出，并具有小轮廓和高灵活性的附加益处。

3. 发明授权

EP2210573B1 NESTED STENT IN BODY LUMEN 有权转让
标题翻译：嵌入式支架置入体腔
公开(公告)号：EP2210573B1
公开(公告)日：2015-12-23
申请号：EP08841842.1
申请日：2008-10-16
申请人： Shanghai MicroPort Medical (Group) Co., Ltd.
发明人： XIE, Zhiyong , LUO, Qiyi , LI, Yu , LI, Jianjun , WANG, Changchun , WANG, Sen , HAO, Xia , TANG, Zhirong
IPC分类号： A61F2/915 , A61F2/82 , A61L27/54
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91533 , A61F2002/91558 , A61F2250/0068

4. 发明公开

EP2614846A1 EMBOLIC AGENT AND PREPARATION METHOD THEREFOR 审中-公开
标题翻译： EMBOLIEMITTEL UND HERSTELLUNGSVERFAHRENDAFÜR
公开(公告)号：EP2614846A1
公开(公告)日：2013-07-17
申请号：EP11819398.6
申请日：2011-08-16
申请人： Shanghai MicroPort Medical (Group) Co., Ltd.
发明人： LI, Yu , KANG, Yahong , JIN, Qiaorong , XIE, Zhiyong , LUO, Qiyi
IPC分类号： A61L31/06 , A61L31/04 , A61L31/18 , A61F2/02
CPC分类号： A61L24/0042 , A61K9/0019 , A61K47/12 , A61L24/001 , A61L2430/36
摘要： An embolic agent and a preparation method therefore are disclosed. The embolic agent comprises a liquid embolic material, a degradable polymer, and a contrast agent. The preparation method comprises physically blending a degradable polymer and a liquid embolic material, or chemically bonding the degradable polymer to the liquid embolic material, to obtain a first solution; adding a contrast agent to the first solution, to obtain the embolic agent. Due to the gradual degradation of the degradable polymer, an embolic body forms a system with a porous structure, thereby lowering the density of the embolic agent and effectively relieving the mass effect.
摘要翻译：因此，公开了栓塞剂及其制备方法。栓塞剂包括液体栓塞材料，可降解聚合物和造影剂。制备方法包括物理混合可降解聚合物和液体栓塞材料，或将可降解聚合物化学键合到液体栓塞材料上，以获得第一溶液; 向第一溶液中加入造影剂，以获得栓塞剂。由于可降解聚合物的逐渐降解，栓塞体形成具有多孔结构的系统，从而降低栓塞剂的密度并有效地缓解了质量效应。

5. 发明授权

EP2353551B1 CORONARY ARTERY VASCULAR STENT WITH MEDICINE CARRYING SLOTS 有权转让
标题翻译： KORONARARTERIENSTENT与药物包衣角子机
公开(公告)号：EP2353551B1
公开(公告)日：2016-10-26
申请号：EP09824395.9
申请日：2009-11-02
申请人： Shanghai MicroPort Medical (Group) Co., Ltd.
发明人： LI, Yan , WANG, Changchun , LI, Jianjun , XIE, Zhiyong , TANG, Zhirong , LUO, Qiyi
IPC分类号： A61F2/82 , A61M31/00 , A61F2/91 , A61F2/915
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91558 , A61F2230/0054 , A61F2250/0068

6. 发明公开

EP2777749A1 BALLOON DILATION CATHETER 有权转让
标题翻译： BALLON-DILATATIONSKATHETER
公开(公告)号：EP2777749A1
公开(公告)日：2014-09-17
申请号：EP12848488.8
申请日：2012-11-09
申请人： Shanghai MicroPort Medical (Group) Co., Ltd.
发明人： XIE, Zhiyong , SUN, Fanghua , LI, Xiaoxiu , LU, Huina , ZHANG, Yingtao , ZHU, Jiaying , SONG, Linfei , GUO, Fang , LUO, Qiyi
IPC分类号： A61M25/10 , A61M29/02
CPC分类号： A61M25/1006 , A61M25/0051 , A61M25/104
摘要： A balloon dilation catheter comprises an outer tube (1), a reinforcing tube (2), a balloon (4), an inner tube (3) and a connector (6). The reinforcing tube (2) runs through the inner chamber of the outer tube (1). The distal end of the reinforcing tube (2) passes through the balloon (4), and is sealed with and fixed to the distal end of the balloon (4). A plurality of hollowed-out grooves (21) are provided in the reinforcing tube (2). The inner tube (3) runs through the inner chamber of the reinforcing tube (2). The distal end of the inner tube (3) protrudes from the distal end of the reinforcing tube (2), and is sealed with and fixed to the balloon (4). The connector (6) is fixed to the proximal end of the outer tube (1), and is provided thereon with a first connection port (61) and a second connection port (62). Compared with the existing reinforcing tube formed as a whole tube, the present balloon dilation catheter can change a bending angle automatically and flexibly to fit with blood vessels, thus reducing a damage to the blood vessels during delivery and withdrawal.
摘要翻译：球囊扩张导管包括外管（1），加强管（2），球囊（4），内管（3）和连接器（6）。加强管（2）穿过外管（1）的内腔。加强管（2）的前端通过球囊（4），并且被密封并固定到球囊（4）的远端。在加强管（2）中设置有多个中空槽（21）。内管（3）穿过加强管（2）的内腔。内管（3）的前端从加强管（2）的前端突出，与气囊（4）密封固定。连接器（6）固定在外管（1）的基端，并在其上设置有第一连接口（61）和第二连接口（62）。与作为整体管形成的现有的加强管相比，本发明的球囊扩张导管可以自动且灵活地改变弯曲角度以适应血管，从而减少在输送和抽出期间对血管的损伤。

7. 发明公开

EP2769701A1 INTRAVASCULAR IMPLANT DEVICE KIT AND PREPARATION METHOD FOR IMPLANT DEVICE 审中-公开
标题翻译： INTRAVASKULÄRESIMPLANTAT-KIT UND VERFAHREN ZUR HERSTELLUNG EINER IMPLANTATVORRICHTUNG
公开(公告)号：EP2769701A1
公开(公告)日：2014-08-27
申请号：EP11874217.0
申请日：2011-12-16
申请人： Shanghai MicroPort Medical (Group) Co., Ltd.
发明人： XIE, Zhiyong , KANG, Yahong , JIN, Qiaorong , CHEN, Bing , ZHANG, Jiuli , LV, Jian , XU, Xiaohong , WANG, Sen , LUO, Qiyi
IPC分类号： A61F2/82 , A61F2/86 , A61F2/92 , A61F2/06
CPC分类号： A61F2/07 , A61F2/90 , A61F2/945 , A61F2002/072
摘要： An intravascular implant device kit and a preparation method for implant device. The implant device is an intravascular stent locally covered with a film, which can be implanted in a blood vessel to treat vascular diseases such as aneurysm, particularly intracranial aneurysm. The implant device kit comprises a film material to be coated and a mesh stent, wherein the main component of the film material is alkyl cyanoacrylate. The implant device is directly filmed on site at the position of the aneurysm neck by the preparation method, which enables the aneurysm neck to be accurately and quickly blocked, the branch to be kept patent, and the space occupying effect to be obviously improved, and thus realizing a real cure of the aneurysm.
摘要翻译：血管内植入装置套件和植入装置的制备方法。植入装置是局部覆盖有膜的血管内支架，其可以植入血管中以治疗血管疾病如动脉瘤，特别是颅内动脉瘤。植入装置套件包括待涂覆的薄膜材料和网状支架，其中薄膜材料的主要成分是氰基丙烯酸烷基酯。通过制备方法，在动脉瘤颈部的位置直接成像植入装置，能够使动脉瘤颈部准确而快速地封闭，分支保持专利，空间占有效果明显提高，从而实现动脉瘤的真正治愈。

8. 发明公开

EP2722062A1 LIQUID EMBOLIC MATERIALS BASED ON COLLAGENS AND PREPARATION METHOD THEREOF 审中-公开
标题翻译： FLUSIIGES EMBOLISIERUNGSMATERIAL AUF基于VON KOLLAGENEN UND HERSTELLUNGSVERFAHRENDAFÜR
公开(公告)号：EP2722062A1
公开(公告)日：2014-04-23
申请号：EP12800524.6
申请日：2012-06-15
申请人： Shanghai MicroPort Medical (Group) Co., Ltd.
发明人： LENG, Bing , KANG, Yahong , JIN, Qiaorong , XIE, Zhiyong , LUO, Qiyi
IPC分类号： A61L31/04 , A61L31/06 , A61L31/18 , A61K33/14 , A61K33/18 , C08K3/10 , C08K3/16
CPC分类号： A61K39/39 , A61K35/74 , A61K45/06 , A61L24/001 , A61L24/0094 , A61L24/02 , A61L2300/442 , A61L2400/06 , A61L2430/36 , C08L89/06 , A61K2300/00 , C08L35/04
摘要： The present invention relates to the field of medical devices. Specifically, the present invention relates to a novel collagen-based liquid embolic material and its preparation method. The alkyl cyanoacrylate and the collagen contained in the embolic material self-assemble into a multiple-junction polymer during embolization, to thereby produce an embolic material system. In one aspect, the alkyl cyanoacrylate, as a typical liquid embolic material, has a good embolic effect; and, in another aspect, the collagen can absorb water and expand rapidly, and can induce the increase of endothelial growth factor upon embolization, which provides an embolic body with a low density and a good flexibility, as well as a permanent embolization with no recurrence.
摘要翻译：本发明涉及医疗器械领域。具体而言，本发明涉及一种新型的基于胶原的液体栓塞材料及其制备方法。包含在栓塞材料中的氰基丙烯酸烷基酯和胶原蛋白在栓塞期间自组装成多重聚合物，从而产生栓塞物质系统。一方面，作为典型的液体栓塞材料，氰基丙烯酸烷基酯具有良好的栓塞作用; 另一方面，胶原蛋白可以吸收水分并迅速膨胀，并可引起栓塞后内皮生长因子的增加，提供低密度和良好的柔韧性的栓塞体以及无复发的永久性栓塞。

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