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1. 发明公开

EP3382002A1 COMPOSITION FOR CONTACT LENS 有权
公开(公告)号：EP3382002A1
公开(公告)日：2018-10-03
申请号：EP17190771.0
申请日：2017-09-13
申请人： Pegavision Corporation
发明人： CHANG, Han-Yi , CHEN, Li-Ju
IPC分类号： C11D3/00 , C11D3/37 , C11D1/04 , C11D1/24 , C11D1/29 , C11D1/72 , C11D1/14 , C11D1/34 , C11D1/66 , C11D3/20 , C11D3/18
CPC分类号： C11D3/0078 , C11D1/04 , C11D1/146 , C11D1/29 , C11D1/34 , C11D1/667 , C11D1/72 , C11D3/188 , C11D3/2024 , C11D3/2037 , C11D3/2062 , C11D3/2093
摘要： The present invention provides a composition for contact lenses. The composition includes an algefacient and a surfactant, wherein the surfactant includes one or a combination of sodium lauroyl lactylate, polyoxyethylene laureth sulfate, polyoxyethylene hardened castor oil, polyvinylpyrrolidone (PVP), sodium dodecyl sulfate (SDS), TWEEN 80™ and GEROPON™ SBFA-30.

2. 发明公开

EP3895693A1 HYDROGEL COMPOSITION AND HYDROGEL LENS 有权
公开(公告)号：EP3895693A1
公开(公告)日：2021-10-20
申请号：EP21167820.6
申请日：2021-04-12
申请人： Pegavision Corporation
发明人： WU, Hsin-Yi , LEE, Chong-Wei , CHEN, Chun-Han , CHANG, Han-Yi
IPC分类号： A61K9/00 , A61K47/32 , A61K47/34 , A61M35/00
摘要： A hydrogel composition (100) and a hydrogel lens are provided. The hydrogel composition (100) includes a hydrophilic monomer (2), a cross-linker, an initiator, and a rotaxane compound (1). In the hydrogel composition (100), a content range of the hydrophilic monomer (2) is between 60 wt% and 99.85 wt%, a content range of the cross-linker is between 0.01 wt% and 1 wt%, a content range of the initiator is between 0.01 wt% and 2 wt%, and a content range of the rotaxane compound (1) is between 0.1 wt% and 15 wt%. The rotaxane compound (1) further includes at least one cyclic molecule (12) and at least one linear molecule (11) passing through the at least one cyclic molecule (12) in a string manner, and a weight ratio of the rotaxane compound (1) relative to the hydrophilic monomer (2) is between 1:6 and 1:99.

3. 发明公开

EP2610281A1 Method of manufacturing hydrophilic silicone prepolymer 有权
标题翻译：一种制备亲水性Silikonprepolymer过程
公开(公告)号：EP2610281A1
公开(公告)日：2013-07-03
申请号：EP12199660.7
申请日：2012-12-28
申请人： Pegavision Corporation
发明人： TING, Wei-Jia , LI, Heng-Yi , LAI, Yu-Chin , CHANG, Han-Yi
IPC分类号： C08G77/458 , C08G18/61 , G02B1/04
CPC分类号： C07F7/0879 , C07F7/0854 , C08G18/61 , C08G18/672 , C08G18/755 , C08G18/8116 , C08G77/458 , G02B1/043 , C08L83/04
摘要： A method for manufacturing a hydrophilic silicone prepolymer is disclosed. The method comprises ring-opening polymerization (ROP) of cyclosiloxanes, hydrosilylation of polysiloxanes, copolymerization, and end-capping reaction. After the above processes, the hydrophilic silicone prepolymer can be obtained.

4. 发明公开

EP3263684A1 SOLUTION FOR TREATING CONTACT LENS AND CONTACT LENS PACKAGING SYSTEM 有权
标题翻译：处理接触透镜和接触透镜包装系统的解决方案
公开(公告)号：EP3263684A1
公开(公告)日：2018-01-03
申请号：EP17157314.0
申请日：2017-02-22
申请人： Pegavision Corporation
发明人： LAI, Yu-Chin , YEH, Min-Tzong , CHANG, Han-Yi , CHANG, Ya-Hui
IPC分类号： C11D3/00 , A61K9/00 , A61L12/00 , C11D3/22 , C11D3/37
CPC分类号： A61L12/14 , A61L12/08 , A61L12/086 , C11D3/0078 , C11D3/227 , C11D3/3784
摘要： A solution for treating a contact lens and a contact lens packaging system are provided. The solution includes about 0.01 to about 1.0 parts by weight (pbw) of a polymer having phosphorylcholine groups, about 0.005 to about 0.05 pbw of a hydrophilic molecule, about 0.01 to about 1.0 pbw of an inorganic salt, and about 100 pbw of water. A number-average molecular weight of the polymer is about 4,000 to about 1,000,000 daltons. The polymer has a structure of formula (I):

wherein, in formula (I), m is a positive integer, n is zero or a positive integer, and R is C 2 -C 12 alkyl group, or C 2 -C 12 hydroxyalkyl group. When n is a positive integer, m/n is greater than 1. Moreover, a number-average molecular weight of the hydrophilic molecule is about 10,000 to about 5,000,000 daltons. The hydrophilic molecule is hyaluronic acid (HA) or hyaluronate salt.
摘要翻译：提供了用于处理隐形眼镜和隐形眼镜包装系统的解决方案。该溶液包含约0.01至约1.0重量份（pbw）具有磷酸胆碱基团的聚合物，约0.005至约0.05pbw的亲水分子，约0.01至约1.0pbw的无机盐和约100pbw的水。聚合物的数均分子量为约4,000至约1,000,000道尔顿。该聚合物具有式（I）的结构：其中，在式（I）中，m为正整数，n为零或正整数，并且R为C2-C12烷基或C2-C12羟烷基。当n是正整数时，m / n大于1.此外，亲水分子的数均分子量为约10,000至约5,000,000道尔顿。亲水分子是透明质酸（HA）或透明质酸盐。

5. 发明公开

EP4431581A1 CONTACT LENS AND FABRICATION METHOD THEREFOR 审中-实审
公开(公告)号：EP4431581A1
公开(公告)日：2024-09-18
申请号：EP21949520.7
申请日：2021-11-12
申请人： Pegavision Corporation
发明人： LI, Ting-Yu , CHANG, Han-Yi
IPC分类号： C09K3/00
CPC分类号： C09K3/00
摘要： A contact lens and its manufacturing method are provided. The contact lens includes a lens and a hydrophilic coating that is attached to a surface of the lens by hydrogen bonding, ionic bonding, or a combination thereof. The hydrophilic coating includes polyacrylic acid and carbohydrate. Another contact lens includes a lens, a first hydrophilic coating, and a second hydrophilic coating. The first hydrophilic coating is attached to a surface of the lens by hydrogen bonding, ionic bonding, or a combination thereof and includes polyacrylic acid. The second hydrophilic coating is disposed on the first hydrophilic coating. The second hydrophilic coating includes polyvinylpyrrolidone, poloxamine, poloxamer, methylcellulose, hydroxypropyl methylcellulose, carboxymethyl cellulose, ascorbic acid, poly(2-methacryloyloxyethyl phosphorylcholine), hyaluronic acid, alginic acid, polyglutamic acid, carbohydrate, or combinations thereof. The carbohydrate includes monosaccharide, disaccharide, or a combination thereof. The contact lenses have high hydrophilicity and high stability, and the hydrophilic coatings have good adhesion.

6. 发明授权

EP3263684B1 SOLUTION FOR TREATING CONTACT LENS AND CONTACT LENS PACKAGING SYSTEM 有权
公开(公告)号：EP3263684B1
公开(公告)日：2019-03-13
申请号：EP17157314.0
申请日：2017-02-22
申请人： Pegavision Corporation
发明人： LAI, Yu-Chin , YEH, Min-Tzong , CHANG, Han-Yi , CHANG, Ya-Hui
IPC分类号： C11D3/00 , A61K9/00 , A61L12/00 , C11D3/22 , C11D3/37

7. 发明公开

EP3263683A1 SOLUTION FOR TREATING CONTACT LENS 无效
标题翻译：处理接触镜片的解决方案
公开(公告)号：EP3263683A1
公开(公告)日：2018-01-03
申请号：EP16195567.9
申请日：2016-10-25
申请人： Pegavision Corporation
发明人： CHANG, Han-Yi , LIAO, Ya-Hsuan , LU, Shu-Chen , CHANG, Ya-Hui , LAI, Yu-Chin
IPC分类号： C11D3/00 , C11D3/04 , C11D3/37 , C11D7/10 , A61K9/00 , A61K9/08 , A61K47/32
CPC分类号： A61L12/14 , A61K9/0048 , A61K9/08 , A61K47/32 , C08F130/02 , C11D3/0078 , C11D3/042 , C11D3/046 , C11D3/168 , C11D3/365 , C11D3/3784 , C11D7/10
摘要： A solution for treating contact lens is provided. The solution includes about 0.01-1.0 parts by weight (pbw) of a polymer having phosphorylcholine groups, about 0.01-1 pbw of an inorganic salt, and about 100 pbw of water. The polymer has a number-average molecular weight of about 4,000 to about 1,000,000 daltons and has a structure of formula (I):

wherein, in formula (I), m is a positive integer, n is zero or a positive integer, and R is C 2 -C 12 alkyl group or C 2 -C 12 hydroxyalkyl group. When n is a positive integer, m/n is greater than 1.
摘要翻译：提供了用于处理隐形眼镜的解决方案。该溶液包含约0.01-1.0重量份（pbw）的具有磷酸胆碱基团的聚合物，约0.01-1重量份的无机盐和约100重量份的水。该聚合物具有约4,000至约1,000,000道尔顿的数均分子量，并具有式（I）的结构：其中，在式（I）中，m是正整数，n是零或正整数，并且R 是C 2 -C 12烷基或C 2 -C 12羟烷基。当n是正整数时，m / n大于1。

8. 发明授权

EP2610281B1 Method of manufacturing hydrophilic silicone prepolymer 有权
标题翻译： Verfahren zur Herstellung von亲水Silikonprepolymer
公开(公告)号：EP2610281B1
公开(公告)日：2017-02-15
申请号：EP12199660.7
申请日：2012-12-28
申请人： Pegavision Corporation
发明人： TING, Wei-Jia , LI, Heng-Yi , LAI, Yu-Chin , CHANG, Han-Yi
IPC分类号： C08G77/458 , C08G18/61 , G02B1/04
CPC分类号： C07F7/0879 , C07F7/0854 , C08G18/61 , C08G18/672 , C08G18/755 , C08G18/8116 , C08G77/458 , G02B1/043 , C08L83/04

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