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1. 发明公开

EP3932387A1 PADDAUA LIPID COMPOSITION FOR MODULATING FUNCTIONS OF KERATINOUS MATERIALS, METHOD FOR MODULATING SAID FUNCTIONS AND USE OF SAID PLANT LIPIDS 审中-公开
公开(公告)号：EP3932387A1
公开(公告)日：2022-01-05
申请号：EP21179563.8
申请日：2013-10-01
申请人： Natura Cosméticos S.A.
发明人： FERRARI, Cintia Rosa , ZIMBARDI, Daniela , PLACONÁ DINIZ, Gabriela , DE ASSIS SANTOS, Ícaro , LORENCINI, Marcio , DA LUZ MOREIRA, Patrícia
IPC分类号： A61K8/9794 , A61K36/889 , A61Q19/00 , A61Q17/00 , A61P17/16 , A61P43/00 , A61Q19/08 , A61K8/92
摘要： The present invention is directed to cosmetic and/or pharmaceutical compositions comprising at least one plant lipid, having as its main application the treatment of keratinous materials, particularly skin, hair, scalp, nails and eyelashes, by modulating the expression of genes responsible for ROS metabolism, lipid metabolism, skin integrity, cell renewal, cell differentiation, strengthening the skin barrier, calcium metabolism, cell proliferation, tissue healing and/or repair, cell adhesion, carbohydrate metabolism, hydration, skin homeostasis/maintenance, skin defense and/or protection, remodeling and/or extracellular matrix synthesis, skin peeling, tissue maintenance, cell signaling, normal development of the epidermis, epidermal barrier function, development of the skin, dermis-epidermis junction, antiinflammatory or antioxidant action in keratinous materials, through the modulation of the expression of the genes involved in said functions. The present invention also teaches methods of modulating the expression of genes responsible for such functions of keratinous materials and the use of said plant lipids in the preparation of said compositions.

2. 发明公开

EP2493448A1 COSMETIC COMPOSITION COMPRISING SILICONED SAPUCAINHA ESTER 有权
标题翻译：化妆品组合含有硅化SAPUCAINHA酯
公开(公告)号：EP2493448A1
公开(公告)日：2012-09-05
申请号：EP10778540.4
申请日：2010-08-27
申请人： Natura Cosméticos S.A.
发明人： DADARIO BRUGNOLLO, Erica , SCARPARO DE SANCTIS, Daisy de Fatima , MORAES SANTOS, Leandra , LORENCINI, Marcio , MOURA SA ROCHA, Vanessa de , FIGUEIREDO BEDA, Debora
IPC分类号： A61K8/37 , A61Q19/00
CPC分类号： A61Q1/08 , A61K8/585
摘要： The present invention relates to a cosmetic composition comprising siliconed sapucainha ester, compound which can be used as a cosmetic excipient replacing silicones for several applications. The present invention further relates to cosmetic products comprising said composition.

3. 发明授权

EP2512495B1 PROCESS FOR OBTAINING A STANDARDISED EXTRACT OF QUERCETIN AN 3-O-METHYLQUERCETIN FROM FLOWERS OF MACELA (ACHYROCLINE SATUREIOIDES), AND COSMETIC AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID EXTRACT 有权
标题翻译：用于生产STANDARDISIERSTES槲皮素和3-O-甲基槲皮素EXTRACT FROM Macela（Achyrocline satureioides）花，与化妆品和药物ZUSAMMENZETZUNGEN TO THE提取包含
公开(公告)号：EP2512495B1
公开(公告)日：2015-09-09
申请号：EP11710252.5
申请日：2011-01-06
申请人： Natura Cosméticos S.A.
发明人： MOURA SA ROCHA, Vanessa de , DELARCINA JUNIOR, Sergio , FIGUEREDO BEDA, Débora , LORENCINI, Marcio , COSTA BEBER, Tiago , PASSERO, Alan
IPC分类号： A61K36/28 , A61P17/10 , A61P29/00
CPC分类号： A61K36/28 , A61K2236/331

4. 发明授权

EP2493448B1 COSMETIC COMPOSITION COMPRISING A SILICONED SAPUCAINHA ESTER 有权
标题翻译：化妆品组合含有硅化SAPUCAINHA酯
公开(公告)号：EP2493448B1
公开(公告)日：2014-10-08
申请号：EP10778540.4
申请日：2010-10-27
申请人： Natura Cosméticos S.A.
发明人： DADARIO BRUGNOLLO, Erica , SCARPARO DE SANCTIS, Daisy de Fatima , MORAES SANTOS, Leandra , LORENCINI, Marcio , MOURA SA ROCHA, Vanessa de , FIGUEIREDO BEDA, Debora
IPC分类号： A61K8/58 , A61Q1/08
CPC分类号： A61Q1/08 , A61K8/585

5. 发明公开

EP2903590A2 PLANT LIPID COMPOSITION FOR MODULATING FUNCTIONS OF KERATINOUS MATERIALS, METHOD FOR MODULATING SAID FUNCTIONS AND USE OF SAID PLANT LIPIDS 有权
标题翻译：植物脂质用于调制的角蛋白材料的功能的组成，方法调制这些特征和使用时，所述植物脂质学报
公开(公告)号：EP2903590A2
公开(公告)日：2015-08-12
申请号：EP13786146.4
申请日：2013-10-01
申请人： Natura Cosméticos S.A.
发明人： FERRARI, Cintia Rosa , ZIMBARDI, Daniela , PLACONÁ DINIZ, Gabriela , DE ASSIS SANTOS, Ícaro , LORENCINI, Marcio , DA LUZ MOREIRA, Patrícia
IPC分类号： A61K8/97
CPC分类号： A61K8/922 , A61K2800/75 , A61Q17/00 , A61Q19/08
摘要： The present invention is directed to cosmetic and/or pharmaceutical compositions comprising at least one plant lipid, having as its main application the treatment of keratinous materials, particularly skin, hair, scalp, nails and eyelashes, by modulating the expression of genes responsible for ROS metabolism, lipid metabolism, skin integrity, cell renewal, cell differentiation, strengthening the skin barrier, calcium metabolism, cell proliferation, tissue healing and/or repair, cell adhesion, carbohydrate metabolism, hydration, skin homeostasis/maintenance, skin defense and/or protection, remodeling and/or extracellular matrix synthesis, skin peeling, tissue maintenance, cell signaling, normal development of the epidermis, epidermal barrier function, development of the skin, dermis-epidermis junction, anti-inflammatory or antioxidant action in keratinous materials, through the modulation of the expression of the genes involved in said functions. The present invention also teaches methods of modulating the expression of genes responsible for such functions of keratinous materials and the use of said plant lipids in the preparation of said compositions.
摘要翻译：本发明涉及化妆品和/或药物组合物包含至少一种植物脂质，具有角质材料，尤其是皮肤，头发，头皮，指甲和睫毛的治疗作为其主要应用，通过调节负责ROS的基因的表达代谢，脂质代谢，皮肤完整性，细胞更新，细胞分化，加强皮肤屏障，钙代谢，细胞增殖，组织愈合和/或修复的细胞，粘附，碳水化合物代谢，水合，皮肤稳态/维护，皮肤防御和/或保护，重塑和/或细胞外基质的合成，皮肤剥离，组织维护，细胞信号传导，表皮的正常发育，表皮屏障功能，皮肤的发展，真皮 - 表皮交界处，在角蛋白材料的抗炎或抗氧化作用，通过在根据所述函数所涉及的基因的表达的调节。因此，本发明教导了调制负责角质材料的搜索功能和使用时，所述的计划脂质所说的组合物的制备中的基因的表达的方法。

6. 发明公开

EP2512495A1 PROCESS FOR OBTAINING A STANDARDISED EXTRACT OF QUERCETIN AND 3-0-METHYLQUERCETIN FROM FLOWERS OF MACELA (ACHYROCLINE SATUREIOIDES), AND COSMETIC AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID EXTRACT 有权
标题翻译：用于生产STANDARDISIERSTES槲皮素和3-O-甲基槲皮素EXTRACT FROM Macela（Achyrocline satureioides）花，与化妆品和药物ZUSAMMENZETZUNGEN TO THE提取包含
公开(公告)号：EP2512495A1
公开(公告)日：2012-10-24
申请号：EP11710252.5
申请日：2011-01-06
申请人： Natura Cosméticos S.A.
发明人： MOURA SA ROCHA, Vanessa de , DELARCINA JUNIOR, Sergio , FIGUEREDO BEDA, Débora , LORENCINI, Marcio , COSTA BEBER, Tiago , PASSERO, Alan
IPC分类号： A61K36/28 , A61P17/10 , A61P29/00
CPC分类号： A61K36/28 , A61K2236/331
摘要： It describes an extraction process for obtaining a standardized extract of quercetin and 3-0-methylquercetin from inflorescences of macela- do-campo (Achyrocline satureioides) characterized by comprising of the following steps: A) grinding the inflorescences of Achyrocline satureioides to obtain a material of ground plant; B) submitting the ground plant to at least four sequential stages of hydro-alcoholic extraction at a temperature from 60°C to 80°C1 for 3 to 4 hours for each stage, in order to obtain 4 intermediary hydro-alcoholic extracts; C) combining the 4 intermediary hydro-alcoholic extracts; D) concentrating the intermediary hydro-alcoholic extracts mixture; in order to obtain up to a maximum of 20% of the initial mass of the intermediary hydro-alcoholic extracts; E) drying the material obtained in (D). It also describes cosmetic, pharmaceutical and veterinary compositions containing the aforesaid extract of macela-do-campo, destined for the prevention and treatment of the damages arising from inflammatory, microbial and oxidation/lypoperoxidation reactions. The use and method of application of the aforesaid extract of macela are also described.

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