会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 1. 发明公开
    • MODIFIED PHOTOSYNTHETIC MICROORGANISMS FOR PRODUCING LIPIDS
    • 生物脂质体修饰的光合微生物
    • EP2655605A1
    • 2013-10-30
    • EP11804899.0
    • 2011-12-19
    • Matrix Genetics, LLC
    • ROBERTS, JamesCROSS, FredKAISER, Brett K.
    • C12N9/02C12P7/64
    • C12P7/6436C12N9/0008C12N15/74C12N15/8242C12N15/8247C12P7/6409C12Y102/0108
    • This disclosure describes genetically modified photosynthetic microorganisms,
      e.g ., Cyanobacteria, that overexpress an acyl-acyl carrier protein reductase (acyl-ACP reductase). These microorganisms may optionally overexpress one or more fatty acid synthesis proteins such as ACP and ACCase, and/or one or more polypeptides associated with glycogen breakdown. Also included are photosynthetic microorganisms comprising mutations or deletions in a glycogen biosynthesis or storage pathway, which accumulate a reduced amount of glycogen under reduced nitrogen conditions as compared to a wild type photosynthetic microorganism. The modified photosynthetic microorganisms provided herein are capable of producing increased amounts of lipids such as fatty acids or wax esters and/or synthesizing triglycerides.
    • 本公开描述了过表达酰基 - 酰基载体蛋白还原酶(酰基-ACP还原酶)的基因修饰的光合微生物,例如蓝细菌。 这些微生物可以任选地过表达一种或多种脂肪酸合成蛋白,例如ACP和ACCase,和/或一种或多种与糖原分解相关的多肽。 还包括光合微生物,其包含糖原生物合成或储存途径中的突变或缺失,与野生型光合微生物相比,其在减少的氮条件下积累减少量的糖原。 本文提供的修饰的光合微生物能够产生增加量的脂质,例如脂肪酸或蜡酯和/或合成甘油三酯。