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1. 发明公开

EP2227725A2 CLINICAL APPLICATIONS OF NEUROPSYCHOLOGICAL PATTERN ANALYSIS AND MODELING 审中-公开
标题翻译：临床应用NEURO心理模式分析与建模
公开(公告)号：EP2227725A2
公开(公告)日：2010-09-15
申请号：EP08855707.9
申请日：2008-11-30
申请人： Elminda Ltd.
发明人： SHAHAF, Goded , BEN-BASSAT, Guy , GORDON, Urit , GEVA, Amir , RECHES, Amit , KANTER, Ayelet , PINCHUK, Noga
IPC分类号： G06E3/00
CPC分类号： A61B5/0482 , A61B5/0488 , A61B5/4064 , G06F19/00 , G16H50/50
摘要： A method for functional analysis of neurophysiological data by decomposing neurophysiological data and EEG signal to form a plurality of signal features. The signal features may then optionally be analyzed to determined one or more patterns.

2. 发明公开

EP3068295A2 METHOD AND SYSTEM FOR MANAGING PAIN 审中-公开
标题翻译： VERFAHREN UND SYSTEMFÜRSCHMERZMANAGEMENT
公开(公告)号：EP3068295A2
公开(公告)日：2016-09-21
申请号：EP14862423.2
申请日：2014-11-11
申请人： Elminda Ltd.
发明人： GADOT, Ronen , GEVA, Amir B. , RECHES, Amit , STERN, Yaki
IPC分类号： A61B5/04 , A61B5/05 , G06K9/00
CPC分类号： A61B5/0476 , A61B5/04012 , A61B5/4064 , A61B5/4343 , A61B5/4824 , A61B5/4848 , A61B5/7264 , A61N1/36021 , A61N1/36071 , A61N1/36139 , G06F19/00 , G06F19/3481 , G16H50/50 , G16H50/70
摘要： A method of managing pain using neurophysiological data acquired from the brain of a subject is disclosed. The method comprises: identifying activity-related features in the data; parceling the data according to the activity-related features to define a plurality of capsules, each representing a spatiotemporal activity region in the brain; comparing at least some of the defined capsules to at least one reference capsule; and assessing the likelihood that the subject is experiencing pain responsively to the comparison.
摘要翻译：公开了一种使用从受试者脑部获取的神经生理学数据来治疗疼痛的方法。该方法包括：识别数据中的活动相关特征; 根据活动相关特征来分析数据以定义多个胶囊，每个胶囊代表大脑中的时空活动区域; 将至少一些所定义的胶囊与至少一个参考胶囊进行比较; 并评估受试者对比较反应的疼痛的可能性。

3. 发明公开

EP2526500A2 METHOD AND SYSTEM FOR WEIGHTED ANALYSIS OF NEUROPHYSIOLOGICAL DATA 审中-公开
标题翻译： VERFAHREN UND SYSTEMFÜRGEWICHTETE ANALYZE VON神经生理学日期
公开(公告)号：EP2526500A2
公开(公告)日：2012-11-28
申请号：EP11705277.9
申请日：2011-01-18
申请人： Elminda Ltd.
发明人： SHAHAF, Goded , RECHES, Amit , GEVA, Amir, B. , PINCHUK, Noga , BEN-BASSAT, Guy , KANTER, Ayelet , SHANI-HERSHKOVICH, Revital , GADOT, Ronen , STERN, Yaki
IPC分类号： G06F19/00
CPC分类号： A61B5/048 , A61B5/0484 , A61B5/4064 , G06F19/00 , G16H50/30 , G16H50/70
摘要： A method of analyzing neurophysiological data is disclosed. The method comprises: identifying activity-related features in the data, constructing a brain network activity (BNA) pattern having a plurality of nodes, each representing a feature of the activity-related features, and assigning a connectivity weight to each pair of nodes in the BNA pattern.
摘要翻译：公开了一种分析神经生理数据的方法。该方法包括：识别数据中的活动相关特征，构建具有多个节点的大脑网络活动（BNA）模式，每个节点表示活动相关特征的特征，以及为每对节点分配连接权重 BNA模式。

4. 发明公开

EP2227138A2 FUNCTIONAL ANALYSIS OF NEUROPHYSIOLOGICAL DATA 审中-公开
标题翻译： NEURO生理数据功能评价
公开(公告)号：EP2227138A2
公开(公告)日：2010-09-15
申请号：EP08854552.0
申请日：2008-11-30
申请人： Elminda Ltd.
发明人： SHAHAF, Goded , GEVA, Amir , CARMELI, Tomer , PINCHUK, Noga , TAUBER, Israel , RECHES, Amit , BEN-BASSAT, Guy , KANTER, Ayelet , GORDON, Urit
IPC分类号： A61B5/04
CPC分类号： A61B5/04012 , A61B5/04009 , A61B5/0476 , A61B5/0482 , A61B5/7203 , A61B5/726 , A61B5/742
摘要： A method for functional analysis of neurophysiological data by decomposing neurophysiological data and EEG signal to form a plurality of signal features. The signal features may then optionally be analyzed to determined one or more patterns.

5. 发明授权

EP2734107B1 METHOD AND SYSTEM FOR ESTIMATING BRAIN CONCUSSION 有权
标题翻译：估计大脑讨论的方法和系统
公开(公告)号：EP2734107B1
公开(公告)日：2017-05-24
申请号：EP12750826.5
申请日：2012-07-19
申请人： Elminda Ltd.
发明人： GEVA, Amir, B. , RECHES, Amit , GADOT, Ronen
IPC分类号： A61B5/048 , A61B5/0484 , A61B5/00 , G06F19/00
CPC分类号： A61B5/4848 , A61B5/048 , A61B5/0484 , A61B5/4064 , G06F19/00 , G16H50/30 , G16H50/70
摘要： A method of estimating the likelihood of brain concussion from neurophysiological data acquired from the brain of the subject is disclosed. The method comprises: identifying activity-related features in the data; constructing a subject-specific brain network activity (BNA) pattern having a plurality of nodes, wherein each node represents a feature of the activity-related features, and each pair of nodes is assigned with a connectivity weight; calculating a BNA pattern similarity describing a comparison between the constructed BNA pattern and a baseline BNA pattern being specific to the subject; and assessing the likelihood of brain concussion responsively to the BNA pattern similarity.
摘要翻译：公开了一种估计来自受试者大脑的神经生理学数据的脑震荡可能性的方法。该方法包括：识别数据中的活动相关特征; 构建具有多个节点的主题特定脑网络活动（BNA）模式，其中每个节点表示活动相关特征的特征，并且每对节点被分配有连接权重; 计算描述所构建的BNA图案与特定于所述对象的基线BNA图案之间的比较的BNA图案相似性; 并评估BNA图案相似性对脑震荡的可能性。

6. 发明公开

EP2734107A1 METHOD AND SYSTEM FOR ESTIMATING BRAIN CONCUSSION 有权
标题翻译：方法和系统测量脑SHAKE
公开(公告)号：EP2734107A1
公开(公告)日：2014-05-28
申请号：EP12750826.5
申请日：2012-07-19
申请人： Elminda Ltd.
发明人： GEVA, Amir, B. , RECHES, Amit , GADOT, Ronen
IPC分类号： A61B5/048 , A61B5/0484
CPC分类号： A61B5/4848 , A61B5/048 , A61B5/0484 , A61B5/4064 , G06F19/00 , G16H50/30 , G16H50/70
摘要： A method of estimating the likelihood of brain concussion from neurophysiological data acquired from the brain of the subject is disclosed. The method comprises: identifying activity-related features in the data; constructing a subject-specific brain network activity (BNA) pattern having a plurality of nodes, wherein each node represents a feature of the activity-related features, and each pair of nodes is assigned with a connectivity weight; calculating a BNA pattern similarity describing a comparison between the constructed BNA pattern and a baseline BNA pattern being specific to the subject; and assessing the likelihood of brain concussion responsively to the BNA pattern similarity.

7. 发明公开

EP3579246A1 METHOD AND SYSTEM FOR WEIGHTED ANALYSIS OF NEUROPHYSIOLOGICAL DATA 审中-公开
公开(公告)号：EP3579246A1
公开(公告)日：2019-12-11
申请号：EP18208367.5
申请日：2011-01-18
申请人： Elminda Ltd.
发明人： SHAHAF, Goded , RECHES, Amit , GEVA, Amir B. , PINCHUK, Noga , BEN-BASSAT, Guy , KANTER, Ayelet , SHANI-HERSHKOVICH, Revital , GADOT, Ronen , STERN, Yaki
IPC分类号： G16H50/30 , G16H50/70 , A61B5/048
摘要： A method and system for analyzing neurophysiological data, the neurophysiological data being electroencephalogram (EEG) data collected using a plurality of measuring devices respectively placed at a plurality of different locations on the scalp of a subject, the method comprising:
using a data processor for:
applying multidimensional analysis to the data to extract spatial and non-spatial characteristics of the data, said spatial characteristics describing locations from which the respective data were acquired, and said non-spatial characteristics being obtained by segmenting the data according to the time of acquisition and by performing waveform analysis and extracting waveform characteristics;
defining a plurality of vectors, each including, as components of said vector, said spatial characteristics, and one or more non-spatial characteristics as obtained from said segmentation and said decomposition, thereby providing a plurality of features of the data, each feature being a vector of said plurality of vectors;
constructing a brain network activity (BNA) pattern having a plurality of nodes, each representing a cluster of vectors of data characteristics;
assigning a connectivity weight to each pair of nodes in said BNA pattern; and
transmitting said BNA pattern to a display device or computer-readable medium;

wherein said connectivity weight comprises a weight index calculated based on at least one cluster property selected from the group consisting of: (i) a number of vectors in a corresponding pair of clusters; (ii) a variability among numbers of vectors in said corresponding pair of clusters; (iii) a width of time windows (Δt A , Δt B ,) associated with each cluster of said corresponding pair of clusters; (iv) a latency difference (Δt AB ) separating said corresponding pair of clusters.

8. 发明授权

EP3197350B1 BRAIN STIMULATION TOOL CONFIGURATION 有权
公开(公告)号：EP3197350B1
公开(公告)日：2019-11-06
申请号：EP15843981.0
申请日：2015-09-24
申请人： Elminda Ltd.
发明人： GEVA, Amir B. , PEREMEN, Ziv , STERN, Yaki , RECHES, Amit
IPC分类号： A61B5/048 , A61B5/0484 , A61B5/00 , A61N1/36

9. 发明公开

EP3197350A2 BRAIN STIMULATION TOOL CONFIGURATION 审中-公开
标题翻译：脑刺激工具配置
公开(公告)号：EP3197350A2
公开(公告)日：2017-08-02
申请号：EP15843981.0
申请日：2015-09-24
申请人： Elminda Ltd.
发明人： GEVA, Amir B. , PEREMEN, Ziv , STERN, Yaki , RECHES, Amit
IPC分类号： A61B5/048
摘要： A method of configuring a local brain stimulation tool is disclosed. The method comprises: obtaining a reference brain network activity (BNA) pattern, and a BNA pattern describing a neurophysiological state of the subject, each of the BNA patterns having a plurality of nodes and each node representing a brain location and at least one brain wave frequency. The method further comprises comparing the BNA patterns; and configuring the local brain stimulation tool to apply local brain stimulation at a frequency selected based on the comparison.
摘要翻译：公开了配置局部脑刺激工具的方法。该方法包括：获得参考脑网络活动（BNA）模式和描述该对象的神经生理学状态的BNA模式，每个BNA模式具有多个节点，并且每个节点代表脑部位置和至少一个脑波频率。该方法还包括比较BNA图案; 以及配置局部脑刺激工具以基于比较选择的频率应用局部脑刺激。

10. 发明公开

EP2919647A1 NEUROPHYSIOLOGICAL DATA ANALYSIS USING SPATIOTEMPORAL PARCELLATION 有权
标题翻译：分析NEURO生理数据利用空间 - 时间瓜分
公开(公告)号：EP2919647A1
公开(公告)日：2015-09-23
申请号：EP13855226.0
申请日：2013-11-13
申请人： Elminda Ltd.
发明人： GEVA, Amir B. , STERN, Yaki , RECHES, Amit
IPC分类号： A61B5/0484 , A61B5/048 , G06K9/00 , A61B5/055 , G06F19/00
CPC分类号： A61B5/048 , A61B5/0042 , A61B5/0484 , A61B5/0515 , A61B5/0522 , A61B5/055 , A61B5/165 , A61B5/4064 , A61B5/4076 , A61B5/4836 , A61B5/7246 , A61B5/7267 , A61B5/7275 , A61B5/7282 , A61N1/36135 , G06F17/30598 , G06F19/00 , G06T11/206 , G06T2207/30016 , G16H50/50
摘要： A method of analyzing neurophysiological data recorded from a subject is disclosed. The method comprises identifying activity-related features in the data, and parceling the data according to the activity-related features to define a plurality of capsules, each representing a spatiotemporal activity region in the brain. The method further comprises comparing at least some of the defined capsules to at least one reference capsule, and estimating a brain function of the subject based on the comparison.

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