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    • 6. 发明公开
    • SOLID FORMS OF NEMATOCIDAL SULFONAMIDES
    • FESTE FORMEN VON NEMATOZIDEN SULFONAMIDEN
    • EP2766362A1
    • 2014-08-20
    • EP12773478.8
    • 2012-10-05
    • E. I. Du Pont de Nemours and Company
    • BERGER, Richard, A.HOFFMANN, ChristianMARSHALL, William, J.SHAPIRO, Rafael
    • C07D471/04A01N43/90
    • A01N43/90C07D471/04
    • Disclosed are solid forms of 8-chloro-N-[(2-chloro-5-methoxyphenyl)sulfonyl]-6-(trifluoromethyl)-imidazo[1,2-a]pyridine-2-carboxamide (Compound 1). Methods for the preparation of solid forms of Compound 1 and for the conversion of one solid form of Compound 1 into another are disclosed. Disclosed are nematocidal compositions comprising a nematocidally effective amount of a solid form of Compound 1 and at least one additional component selected from the group consisting of surfactants, solid diluents and liquid carriers. Compositions comprising a mixture of a solid form of Compound 1 and at least one other nematicide, insecticide and/or fungicide are also disclosed. Also disclosed are methods for protecting a plant from nematodes comprising applying to the plant, or portion, or seed thereof, or to the growing medium of the plant, a nematocidally effective amount of Compound 1 comprising the polymorph Form A.
    • 公开了8-氯-N - [(2-氯-5-甲氧基苯基)磺酰基] -6-(三氟甲基) - 咪唑并[1,2-a]吡啶-2-甲酰胺(化合物1)的固体形式。 公开了制备化合物1的固体形式和将一种固体形式的化合物1转化成另一种的方法。 公开了包含杀线虫有效量的化合物1的固体形式的杀线组合物和选自表面活性剂,固体稀释剂和液体载体的至少一种另外的组分。 还公开了包含固体形式的化合物1和至少一种其它杀线虫剂,杀虫剂和/或杀真菌剂的混合物的组合物。 还公开了保护植物免受线虫的方法,包括向植物,或其部分或种子施用植物的生长培养基,包括含有多晶型物质A的杀线虫有效量的化合物1。