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1. 发明公开

EP2433563A2 Implantable analyte sensor 有权转让
标题翻译：植入者分析仪
公开(公告)号：EP2433563A2
公开(公告)日：2012-03-28
申请号：EP11189427.5
申请日：2005-05-02
申请人： DexCom, Inc.
发明人： Goode, Jr. Paul, V , Simpson, Peter, C. , Rhodes, Rathbun, K. , Holmquist, Arnold, L , Tapsak, Mark, A. , Shults, Mark , Carr-Brendel, Victoria , Brauker, James, H , Neale, Paul, V. , McClure, Jason, D. , Brister, Mark
IPC分类号： A61B5/05 , A61B5/00 , A61B5/07 , A61B5/145
CPC分类号： A61B5/0031 , A61B5/076 , A61B5/14532 , A61B5/14865 , A61B2560/04 , A61B2560/0462 , H04B1/03 , Y10T29/49117
摘要： An implantable analyte sensor (12) including a sensor body substantially formed from a water vapor permeable material and electrical components encapsulated within the sensor body, wherein the electrical components comprise RF circuitry (38) and an antenna (42) adapted for RF transmission from the sensor (12) in vivo to a receiver (14) ex vivo, wherein the RF circuitry (38) is spaced a fixed distance from the sensor body so as to support a dielectric constant that enables RF transmission between the sensor (12) in vivo to the receiver (14) ex vivo. The electrochemical glucose sensor comprises a three-electrode system (54) comprising an electrochemical cell comprising a working electrode (54a), reference electrode (54b), and counter electrode (54c); and a potentiostat (24) configured to control a potential between the working electrode and the reference electrode, wherein an allowable range for the counter electrode voltage is set sufficiently wide such that the glucose sensor is configured to react with other reducible species when oxygen becomes limited and sufficiently narrow to ensure the circuitry does not allow excessive current draw or bubble formation to occur when in use.
摘要翻译：一种可植入分析物传感器（12），包括基本上由水蒸汽可渗透材料形成的传感器体和封装在传感器主体内的电气部件，其中电气部件包括RF电路（38）和适于从传感器（12）离体离子到接收器（14），其中RF电路（38）与传感器主体间隔一定距离，以支持介电常数，其能够使体内传感器（12）之间的RF传输离开接收器（14）。电化学葡萄糖传感器包括三电极系统（54），其包括电化学电池，其包括工作电极（54a），参比电极（54b）和对电极（54c）; 以及配置成控制工作电极和参考电极之间的电位的恒电位器（24），其中对电极电压的允许范围被设定得足够宽，使得葡萄糖传感器被配置为当氧被限制时与其它可还原物质反应并且足够窄以确保电路在使用时不允许发生过度的电流消耗或气泡形成。

2. 发明授权

EP2433563B1 Implantable analyte sensor 有权转让
公开(公告)号：EP2433563B1
公开(公告)日：2018-07-11
申请号：EP11189427.5
申请日：2005-05-02
申请人： DexCom, Inc.
发明人： Goode, Jr. Paul, V , Simpson, Peter, C. , Rhodes, Rathbun, K. , Holmquist, Arnold, L , Tapsak, Mark, A. , Shults, Mark , Carr-Brendel, Victoria , Brauker, James, H , Neale, Paul, V. , McClure, Jason, D. , Brister, Mark
IPC分类号： A61B5/05 , A61B5/00 , A61B5/07 , A61B5/145 , A61B5/1486
CPC分类号： A61B5/0031 , A61B5/076 , A61B5/14532 , A61B5/14865 , A61B2560/04 , A61B2560/0462 , H04B1/03 , Y10T29/49117
摘要： An implantable analyte sensor (12) including a sensor body substantially formed from a water vapor permeable material and electrical components encapsulated within the sensor body, wherein the electrical components comprise RF circuitry (38) and an antenna (42) adapted for RF transmission from the sensor (12) in vivo to a receiver (14) ex vivo, wherein the RF circuitry (38) is spaced a fixed distance from the sensor body so as to support a dielectric constant that enables RF transmission between the sensor (12) in vivo to the receiver (14) ex vivo. The electrochemical glucose sensor comprises a three-electrode system (54) comprising an electrochemical cell comprising a working electrode (54a), reference electrode (54b), and counter electrode (54c); and a potentiostat (24) configured to control a potential between the working electrode and the reference electrode, wherein an allowable range for the counter electrode voltage is set sufficiently wide such that the glucose sensor is configured to react with other reducible species when oxygen becomes limited and sufficiently narrow to ensure the circuitry does not allow excessive current draw or bubble formation to occur when in use.

3. 发明公开

EP2433563A3 Implantable analyte sensor 有权转让
标题翻译：可植入的分析物传感器
公开(公告)号：EP2433563A3
公开(公告)日：2013-05-15
申请号：EP11189427.5
申请日：2005-05-02
申请人： DexCom, Inc.
发明人： Goode, Jr. Paul, V , Simpson, Peter, C. , Rhodes, Rathbun, K. , Holmquist, Arnold, L , Tapsak, Mark, A. , Shults, Mark , Carr-Brendel, Victoria , Brauker, James, H , Neale, Paul, V. , McClure, Jason, D. , Brister, Mark
IPC分类号： A61B5/05 , A61B5/00 , A61B5/07 , A61B5/145 , A61B5/1486
CPC分类号： A61B5/0031 , A61B5/076 , A61B5/14532 , A61B5/14865 , A61B2560/04 , A61B2560/0462 , H04B1/03 , Y10T29/49117
摘要： An implantable analyte sensor (12) including a sensor body substantially formed from a water vapor permeable material and electrical components encapsulated within the sensor body, wherein the electrical components comprise RF circuitry (38) and an antenna (42) adapted for RF transmission from the sensor (12) in vivo to a receiver (14) ex vivo, wherein the RF circuitry (38) is spaced a fixed distance from the sensor body so as to support a dielectric constant that enables RF transmission between the sensor (12) in vivo to the receiver (14) ex vivo. The electrochemical glucose sensor comprises a three-electrode system (54) comprising an electrochemical cell comprising a working electrode (54a), reference electrode (54b), and counter electrode (54c); and a potentiostat (24) configured to control a potential between the working electrode and the reference electrode, wherein an allowable range for the counter electrode voltage is set sufficiently wide such that the glucose sensor is configured to react with other reducible species when oxygen becomes limited and sufficiently narrow to ensure the circuitry does not allow excessive current draw or bubble formation to occur when in use.

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