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1. 发明公开

EP3865567A1 LATERAL FLOW ASSAY ANALYSIS 审中-实审
公开(公告)号：EP3865567A1
公开(公告)日：2021-08-18
申请号：EP21167052.6
申请日：2011-08-25
申请人： Charm Sciences Inc.
发明人： MARKOVSKY, Robert, J. , CHARM, Stanley, E. , GRAHAM, Paul, E. , SKIFFINGTON, Richard, T.
IPC分类号： C12M1/34 , G01N33/04 , G01N21/78 , G01N21/84
摘要： Lateral flow assay analysis is shown and described. In one embodiment, the lateral flow assay comprises a surface having a reflectance profile that is adapted to enable monitoring of the assay continuously until the detection of an analyte. In other embodiments, a lateral flow assay system includes an incubator and a reader, wherein the incubator incubates the assay concurrently as the reader generates a test result. Further, an assay measurement apparatus may include an optical detector to perform continuous image detection of the assay to generate a diagnostic test result.

2. 发明公开

EP1044360A1 TEST DEVICE, METHOD AND SYSTEM FOR DETECTION OF AN ANALYTE 有权
标题翻译：检测试剂盒和检测方法的分析物
公开(公告)号：EP1044360A1
公开(公告)日：2000-10-18
申请号：EP98966123.6
申请日：1998-12-31
申请人： CHARM SCIENCES, INC.
发明人： CHARM, Stanley, E. , SKIFFINGTON, Richard , MARKOVSKY, Robert, J. , ZOMER, Eliezer , SAUL,Steven J.
IPC分类号： G01N21/00 , G01N31/22 , G01N33/53 , G01N33/567 , G01N33/543 , G05D7/00
CPC分类号： G01N33/54366 , G01N33/537 , Y10S435/97 , Y10S435/971 , Y10S436/807 , Y10S436/81
摘要： A test device, system and method, the device composed of an elongated, toothbrush-shaped, transparent, plastic housing and a lateral-flow test strip for the detection of an analyte, such as a beta-lactam in milk, in the housing, the housing having an expansion cavity to receive expanded, liquid-contacted, absorbing material in the test strip, and to control lateral flow rate and times in the test strip.

3. 发明公开

EP0703792A1 HIGH TEMPERATURE, SHORT TIME MICROWAVE HEATING SYSTEM AND METHOD OF HEATING HEAT-SENSITIVE MATERIAL 失效
标题翻译：短时高温微波加热系统和方法制热敏感材料
公开(公告)号：EP0703792A1
公开(公告)日：1996-04-03
申请号：EP94920242.0
申请日：1994-06-16
申请人： CHARM SCIENCES, INC.
发明人： CHARM, Stanley, E. , LANDAU, Steven, H. , ZARRINEGHBAL, Hossein , GOLDEN, Robert, F.
IPC分类号： H05B6 , A23L3 , A61L2
CPC分类号： H05B6/802 , A23L3/01 , A61L2/0011 , A61L2/12 , A61L2/24 , H05B6/6455
摘要： A high temperature, short time microwave heating system 10 for heat-sensitive liquid material to inactivate or reduce pathogenic agents or organisms, such as viral contaminants. The system 10 includes a disposable cartridge 26 consisting of a preheater 32, a microwave heating coil 56 and cooler 58 with the heating coil 56 adapted to be easily inserted in and removed from the microwave heating field.

4. 发明公开

EP0576667A1 TEST KIT AND METHOD FOR THE DETERMINATION OF PESTICIDES 失效
标题翻译：同时测定农药检测试剂盒和方法。
公开(公告)号：EP0576667A1
公开(公告)日：1994-01-05
申请号：EP93904519.0
申请日：1993-01-07
申请人： CHARM SCIENCES, INC.
发明人： ZOMER, Eliezer , SAUL, Steven , CHARM, Stanley, E.
IPC分类号： C07D277 , C12Q1 , G01N21 , G01N33
CPC分类号： G01N33/567 , C07D277/64 , C12Q1/66 , G01N33/60 , Y10S435/975
摘要： L'invention se rapporte à un kit et à un procédé de test pour obtenir de façon rapide et avec une grande sensibilité la détection multiple des pesticides aux organophosphates et aux carbamates. Ce procédé de test utilise une préparation de cervelle d'insecte renfermant un mélange de récepteurs ou d'enzymes avec des sites qui agissent en interaction avec les pesticides aux organophosphates et aux carbamates. Les pesticides entraînent une modification ou une réduction importante des activités de la préparation de cervelle d'insecte qui sont reliées selon un rapport inverse à la quantité du pesticide présent dans l'échantillon test. On mesure cette activité en utilisant des analogues ou des substrats traceurs qui, lors de leur exposition à la préparation de cervelle d'insecte, subissent des modifications, et ces changements sont contrôllés par une réaction d'émission lumineuse. Dans un mode de réalisation, comme dans le cas de la luciférine acétyle, on a découvert que l'hydrolyse d'un dérivé de luciférine en luciférine D par une préparation de cervelle d'insecte se révèle extrêmement sensible aux organophosphates et aux carbamates. La luciférine libérée par la réaction est oxydée par l'enzyme luciférase et adénosine triphosphate (ATP), un donneur d'énergie, et émet de la lumière mesurée sous la forme d'une bioluminescence ou d'une chimioluminescence.

5. 发明授权

EP2895595B1 CULTURE MEDIUM METHOD AND DEVICE 有权
公开(公告)号：EP2895595B1
公开(公告)日：2018-11-28
申请号：EP13837509.2
申请日：2013-09-16
申请人： CHARM SCIENCES, INC.
发明人： SALTER, Robert, S. , SKIFFINGTON, Richard, T. , DURBIN, Gregory, W. , CHARM, Stanley, E.
IPC分类号： C12N1/20 , C12Q1/24 , C12M1/00 , C12M1/12 , C12Q1/34 , C12Q1/04 , C12Q1/22 , C12M1/34 , C12N1/22
CPC分类号： C12Q1/045 , C12M23/04 , C12M23/26 , C12M25/14 , C12M41/36 , C12N1/20 , C12N1/22
摘要： Culture medium devices and systems are shown and described. In one embodiment, the device comprises a culture medium adapted for test fluid inoculation without the concerns associated with a spreading step. In particular examples, a printed grid on the outer surface of a culture device is visible on the inner surface for colony counting after a test has been developed. The result is a device that allows for detection, identification, and transportation of various microorganisms without preparation or spreading steps, and more particularly to a culture medium in which a test fluid inoculated thereto diffuses rapidly.

6. 发明公开

EP2203742A1 ASSAY READER INSERT AND METHOD OF MAINTAINING A READER 审中-公开
标题翻译：测试读数装置用途和方法用于维持的读取设备
公开(公告)号：EP2203742A1
公开(公告)日：2010-07-07
申请号：EP08831768.0
申请日：2008-09-22
申请人： Charm Sciences Inc.
发明人： ABRAHAM, Rami , CHARM, Stanley, E.
IPC分类号： G01N33/53
CPC分类号： G01N33/558 , G01N21/77 , G01N21/78 , G01N2021/7759 , G01N2021/7773 , G01N2021/7776 , G01N2021/7786
摘要： An assay reader system incorporating a conventional assay reader, for example a lateral flow reader, and an insert aligned with the reader's sensor to detect an assay result. The insert may include a housing which defines a cavity to receive a removable barrier, wherein the removable barrier can be aligned between the sensor and the test strip. The barrier may include an optical window, and may be cleanable and/or disposable to maintain the accuracy of the reader. Test strips are introduced into the reader through a receiving port within the insert's housing. An air inlet on the insert further maintains the reader's accuracy by allowing air to be tunneled over the housing to remove excess dust, debris, or the like.

7. 发明授权

EP1358459B1 HYGIENE MONITORING 有权
标题翻译：卫生监控
公开(公告)号：EP1358459B1
公开(公告)日：2006-10-11
申请号：EP01961831.3
申请日：2001-08-01
申请人： Charm Sciences Inc.
发明人： SAUL, Steven, J. , FRANCISCO, Cheryl B. , MARKOVSKY, Robert J. , SALTER, Robert, S. , CHARM, Stanley, E.
IPC分类号： G01N1/00 , C12Q1/34 , C12Q1/54 , C12Q1/04 , C12Q1/40 , G01N33/558
CPC分类号： C12Q1/22 , C12Q1/34 , C12Q1/42 , C12Q1/48 , C12Q1/54 , G01N33/523
摘要： A test method and test device for hygiene monitoring of a test sample from a biological material or a surface with a biological material to detect the presence of phosphate and glucose as a measure of hygiene by employing a swab-type, puncturable-membrane test apparatus or a lateral-flow or capillary-flow test apparatus.

8. 发明公开

EP1358459A2 HYGIENE MONITORING 有权
标题翻译：卫生监控
公开(公告)号：EP1358459A2
公开(公告)日：2003-11-05
申请号：EP01961831.3
申请日：2001-08-01
申请人： Charm Sciences Inc.
发明人： SAUL, Steven, J. , BOYER, Cheryl, A. , MARKOVSKY, Robert, J. , SALTER, Robert, S. , CHARM, Stanley, E.
IPC分类号： G01N1/00
CPC分类号： C12Q1/22 , C12Q1/34 , C12Q1/42 , C12Q1/48 , C12Q1/54 , G01N33/523
摘要： A test method and test device for hygiene monitoring of a test sample from a biological material or a surface with a biological material to detect the presence of phosphate and glucose as a measure of hygiene by employing a swab-type, puncturable-membrane test apparatus or a lateral-flow or capillary-flow test apparatus.

9. 发明公开

EP2895595A1 CULTURE MEDIUM METHOD AND DEVICE 有权
标题翻译：方法和装置培养基
公开(公告)号：EP2895595A1
公开(公告)日：2015-07-22
申请号：EP13837509.2
申请日：2013-09-16
申请人： CHARM SCIENCES, INC.
发明人： SALTER, Robert, S. , SKIFFINGTON, Richard, T. , DURBIN, Gregory, W. , CHARM, Stanley, E.
IPC分类号： C12N1/20 , C12Q1/24 , C12M1/00
CPC分类号： C12Q1/045 , C12M23/04 , C12M23/26 , C12M25/14 , C12M41/36 , C12N1/20 , C12N1/22
摘要： Culture medium devices and systems are shown and described. In one embodiment, the device comprises a culture medium adapted for test fluid inoculation without the concerns associated with a spreading step. In particular examples, a printed grid on the outer surface of a culture device is visible on the inner surface for colony counting after a test has been developed. The result is a device that allows for detection, identification, and transportation of various microorganisms without preparation or spreading steps, and more particularly to a culture medium in which a test fluid inoculated thereto diffuses rapidly.

10. 发明公开

EP1945664A2 METHOD AND ANTIBODIES FOR DETECTING NITROFURAN 审中-公开
标题翻译：方法和抗体检测硝基呋喃的
公开(公告)号：EP1945664A2
公开(公告)日：2008-07-23
申请号：EP06801912.4
申请日：2006-08-21
申请人： Charm Sciences Inc.
发明人： LAW, Say-jong , SAUL, Steven J. , CHARM, Stanley, E.
IPC分类号： C07K16/00
CPC分类号： G01N33/9446 , C07K16/44
摘要： An antibody and immunogen for generating an antibody to nitrofuran and/or nitrofuran metabolite such as tissue or protein bound nitrofuran metabolites. Nitrofurans and and/or nitrofuran metabolites in a biological sample can be detected by contacting the sample with the antibodies to form a complex that can be detected. The antibodies may also be incorporated into test kits for the detection of nitrofuran and/or nitrofuran metabolites.

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