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1. 发明授权

EP2603189B1 DEVICE FOR SEALING A VESSEL AND METHOD OF MANUFACTURING A SEALED VESSEL 有权转让
标题翻译：用于密封容器的装置和制造密封容器的方法
公开(公告)号：EP2603189B1
公开(公告)日：2017-04-26
申请号：EP11740674.4
申请日：2011-08-08
申请人： Arte Corporation
发明人： SCHUETZ, Andreas , KAKIUCHI, Makoto , SHIMAZAKI, Seiji , MATSUDA, Teruo
IPC分类号： A61J1/20 , A61M5/24 , A61M5/31
CPC分类号： A61J1/2096 , A61J1/065 , A61J1/2031 , A61J1/2093 , A61M5/284 , A61M5/31511 , A61M2005/3123 , B65B3/003 , B65B2220/14 , B65B2230/02

2. 发明公开

EP2603189A1 DEVICE FOR SEALING A VESSEL AND METHOD OF MANUFACTURING A SEALED VESSEL 有权转让
标题翻译：装置用于船舶密封并产生一个密封容器方法
公开(公告)号：EP2603189A1
公开(公告)日：2013-06-19
申请号：EP11740674.4
申请日：2011-08-08
申请人： Arte Corporation
发明人： SCHUETZ, Andreas , KAKIUCHI, Makoto , SHIMAZAKI, Seiji , MATSUDA, Teruo
IPC分类号： A61J1/20 , A61M5/24 , A61M5/31
CPC分类号： A61J1/2096 , A61J1/065 , A61J1/2031 , A61J1/2093 , A61M5/284 , A61M5/31511 , A61M2005/3123 , B65B3/003 , B65B2220/14 , B65B2230/02
摘要： A device for sealing a vessel, in particular a cartridge (7) or a test-tube for accommodating a freeze-dried pharmaceutical product (S), wherein the vessel (1) comprises at its opening end (3) an opening edge (4) and an adjoining longitudinal portion (5) with an evenly formed inner cross section, including a front plunger (2) to be positioned inside the vessel (1) at the longitudinal portion (5), is characterized in that the front plunger (2) is configured to be positioned in the vessel (1) in a sealing state, in which the front plunger (2) is fully inserted in the vessel (1), or in an exchange state, in which the front plunger (2) is inserted partly in the vessel (1) and partly protrudes over the opening edge (4) of the vessel (1), wherein the front plunger (2) comprises sealing means that are configured to seal the inside of the vessel (1) against the outside when the front plunger (2) is positioned in the sealing state, and one or more communicating grooves (2i) that are configured to place the inside and outside of the vessel (1) in communication with each other when the front plunger (2) is positioned in the exchange state. Furthermore, a method of manufacturing a sealed vessel (1) is disclosed.
摘要翻译：一种用于密封容器的装置，特别是盒（7）或试管用于容纳冻干药物产品（S），worin所述容器（1）在其开口端部（3）包括以开口边缘（4 ），以及相邻的纵向部分（5），其具有均匀地形成的内横截面，其包括前柱塞（2）至（1）在纵向部分（5）中做了前柱塞特点将容器内被定位（2- ）被配置在一密封状态的容器（1），其中，所述前柱塞（2）在容器（1）被完全插入到被定位，或者在交换状态中，其中所述前柱塞（2）是在容器部分地插入（1）和部分地突出于开口边缘（4）的容器（1），worin前柱塞（2）包括密封bedeutet，DASS被构造成密封所述容器（1）抵靠的内当外界前柱塞（2）被定位在所述密封状态，和一个或多个连通槽（2I）也被配置以放置容器（1）的内部和外部连通海誓山盟当前柱塞（2）在交换状态下被定位。进一步，制造密封容器（1）的方法是游离缺失光盘。

3. 发明公开

EP2253349A1 COMBINATION SYRINGE/CONTAINER 审中-公开
标题翻译： KOMBINATION AUS SPRITZE UNDBEHÄLTER
公开(公告)号：EP2253349A1
公开(公告)日：2010-11-24
申请号：EP09712289.9
申请日：2009-02-19
申请人： ARTE CORPORATION
发明人： SHIMAZAKI, Seiji , KAKIUCHI, Makoto
IPC分类号： A61M5/28
CPC分类号： A61M5/3134 , A61M5/28 , A61M5/31505 , A61M2005/3104 , A61M2005/3106 , A61M2005/3139
摘要： In a combined container-syringe (1), a rubber packing (7) that covers the distal end opening of a cylinder (2) at a fitting hole (3d) of a cylindrical tip (3) in an air tight and liquid tight manner, and in which is formed a through hole (7e) that brings a communication hole (3f) formed in a lure tip (3a) and the inside of the cylinder (2) into communication, and a rubber member (8) that is inserted from the distal end side of the communication hole (3f) and blocks the through hole (7e) are provided, and the rubber packing (7) is formed with an elastic body that is corrosion resistant to the liquid medicament. With this combined container-syringe (1), in addition to being able to store it for a long period without deteriorating the liquid medicament, it is possible to observe well the liquid medicament or blood that flows to the cylindrical tip, and moreover preventing leftover liquid medicament after injection becomes possible.
摘要翻译：在组合的容器 - 注射器（1）中，以气密和液密的方式在圆柱形尖端（3）的装配孔（3d）处覆盖圆筒（2）的远端开口的橡胶衬垫（7），并且其中形成有通孔（7e），其使形成在引诱尖端（3a）中的连通孔（3f）和气缸（2）的内部连通;以及橡胶构件（8），其插入设置从连通孔（3f）的前端侧堵塞通孔（7e），橡胶垫（7）形成有对液体药剂具有耐腐蚀性的弹性体。使用这种组合的容器 - 注射器（1），除了能够长时间存放而不使液体药物变质之外，可以很好地观察流到圆柱形尖端的液体药物或血液，并且还防止残留物注射后的液体药物成为可能。

4. 发明授权

EP2812053B1 DEVICE FOR ACCOMMODATING A FREEZE-DRIED PHARMACEUTICAL PRODUCT AND METHOD OF MANUFACTURING A SEALED VESSEL ACCOMMODATING A FREEZE-DRIED PHARMACEUTICAL PRODUCT 有权转让
标题翻译：用于容纳冷冻药物产品的装置和制造冷冻药物产品的密封容器的方法
公开(公告)号：EP2812053B1
公开(公告)日：2017-10-18
申请号：EP13708361.4
申请日：2013-02-11
申请人： Arte Corporation
发明人： KAKIUCHI, Makoto , SHIMAZAKI, Seiji , MATSUDA, Teruo , SCHUETZ, Andreas
IPC分类号： A61M5/28 , A61M5/31 , B65B3/00 , A61J1/20
CPC分类号： B65D83/005 , A61J1/20 , A61J3/00 , A61M5/284 , A61M2005/3123 , B65B3/003 , B65B7/2821 , B65B63/08 , B65B2220/14 , B65B2230/02

5. 发明公开

EP2812053A1 DEVICE FOR ACCOMODATING A FREEZE-DRIED PHARMACEUTICAL PRODUCT AND METHOD OF MANUFACTURING A SEALED VESSEL ACCOMODATING A FREEZE-DRIED PHARMACEUTICAL PRODUCT 有权转让
标题翻译：设备用于接收冻干药物产品和方法生产的密封容器，用于接收冻干药剂产品
公开(公告)号：EP2812053A1
公开(公告)日：2014-12-17
申请号：EP13708361.4
申请日：2013-02-11
申请人： Arte Corporation
发明人： KAKIUCHI, Makoto , SHIMAZAKI, Seiji , MATSUDA, Teruo , SCHUETZ, Andreas
IPC分类号： A61M5/28 , A61M5/31
CPC分类号： B65D83/005 , A61J1/20 , A61J3/00 , A61M5/284 , A61M2005/3123 , B65B3/003 , B65B7/2821 , B65B63/08 , B65B2220/14 , B65B2230/02
摘要： A device for accommodating a freeze-dried pharmaceutical product (S) for reconstitution, comprising: a vessel (1) having at its opening end (3) an opening edge (4) and an adjoining longitudinal portion (5) with an evenly formed inner cross section, a front plunger (2) to be positioned inside the vessel (1) at the longitudinal portion (5), wherein the front plunger (2) is configured to be positioned inside the vessel (1) in a sealing state, in which the front plunger (2) is fully inserted in the vessel (1), or in an exchange state, in which the front plunger (2) is inserted partly in the vessel (1) and partly protrudes over the opening edge (4) of the vessel (1), and wherein the front plunger (2) comprises sealing means that are configured to seal the inside of the vessel (1) against the outside when the front plunger (2) is positioned in the sealing state, and one or more communicating grooves (2i) that are configured to place the inside and outside of the vessel (1) in communication with each other when the front plunger (2) is positioned in the exchange state, is characterized in that the sealing means are dimensioned and/or structured in such a way that the front plunger (2), when an underpressure of predefined strength is applied to the outer environment of the vessel (1), is caused to move inside the vessel (1) toward its opening end (3). Furthermore, a method of manufacturing a sealed vessel (1) accommodating a freeze-dried pharmaceutical product (S) is disclosed.
摘要翻译：一种用于容纳冻干药物产品（S），用于重构的装置，包括：（1）具有在其开口端（3）至开口边缘（4）和上相邻纵向部分的容器（5），其具有均匀地形成帧内横截面，前柱塞（2）在（5）的纵向部分的容器（1）内被定位，worin前柱塞（2）被配置在容器内，以被定位（1）在密封状态下，在其中前柱塞（2）被完全插入在容器（1），或在交换状态中，其中所述前柱塞部分地插入在所述容器（1）（2）和部分地突出于开口边缘（4）所述容器（1），和worin前柱塞（2）包括密封bedeutet，DASS被构造成密封所述容器（1）相对于外部的内侧当前柱塞（2）在密封状态定位，并且一个或多个连通槽（2I）也被配置为放置容器（1）的内部和外部连通瓦特第i个海誓山盟当前柱塞（2）在交换状态下被定位，在DASS特点模具密封装置的尺寸和/或构造在寻求一种方式做了前柱塞（2）当一个预定义的强度的压力下施加到所述容器的外部环境（1）造成的容器（1）朝向其开口端部（3）内移动。进一步，在制造（1）容纳冻干药物产品（S）的密封容器的制造方法是游离缺失光盘。

6. 发明授权

EP2671604B1 COMBINATION CONTAINER/SYRINGE 有权转让
标题翻译：组合容器/注射器
公开(公告)号：EP2671604B1
公开(公告)日：2017-08-23
申请号：EP12741652.7
申请日：2012-02-02
申请人： Arte Corporation
发明人： KAKIUCHI, Makoto , SHIMAZAKI, Seiji
IPC分类号： A61M5/178 , A61M5/31 , A61J1/00 , A61M5/28 , A61M5/34
CPC分类号： A61M5/286 , A61J1/00 , A61M5/347 , A61M2005/287 , A61M2005/3104 , A61M2005/3123 , A61M2005/3132

7. 发明公开

EP2671604A1 COMBINATION CONTAINER/SYRINGE 有权转让
标题翻译：组合TANK /注射器
公开(公告)号：EP2671604A1
公开(公告)日：2013-12-11
申请号：EP12741652.7
申请日：2012-02-02
申请人： Arte Corporation
发明人： KAKIUCHI, Makoto , SHIMAZAKI, Seiji
IPC分类号： A61M5/178 , A61M5/31
CPC分类号： A61M5/286 , A61J1/00 , A61M5/347 , A61M2005/287 , A61M2005/3104 , A61M2005/3123 , A61M2005/3132
摘要： A combination container/syringe (1) provided with an outer cylinder (10) that forms a cylindrical shape centered on an axial line (O); a front stopper that is inserted into a distal end side of the outer cylinder (10); and a cylindrical tip (50) that is fitted to an outer periphery of the distal end of the outer cylinder via a fitting hole (61) at a base end side, and that has a bypass chamber (71) that houses the front stopper at a front side of the fitting hole, in which an inner diameter of the bypass chamber is formed larger than an outer diameter of the front stopper, and a plurality of ribs (74) that protrude toward an inside in a radial direction and extend in the direction of the axial line to make close contact with the outer peripheral surface of the front stopper that has moved to the inside of the bypass chamber are provided spaced apart in a circumferential direction on the inner peripheral surface (73) of the bypass chamber. According to this combination container/syringe, it is possible to effectively eliminate air bubbles in a medicinal solution via a medicinal solution flow-through space that is formed over the circumferential direction between the inner peripheral surface of the bypass chamber and the outer peripheral surface of the front stopper.

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