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1. 发明授权

EP2603189B1 DEVICE FOR SEALING A VESSEL AND METHOD OF MANUFACTURING A SEALED VESSEL 有权转让
标题翻译：用于密封容器的装置和制造密封容器的方法
公开(公告)号：EP2603189B1
公开(公告)日：2017-04-26
申请号：EP11740674.4
申请日：2011-08-08
申请人： Arte Corporation
发明人： SCHUETZ, Andreas , KAKIUCHI, Makoto , SHIMAZAKI, Seiji , MATSUDA, Teruo
IPC分类号： A61J1/20 , A61M5/24 , A61M5/31
CPC分类号： A61J1/2096 , A61J1/065 , A61J1/2031 , A61J1/2093 , A61M5/284 , A61M5/31511 , A61M2005/3123 , B65B3/003 , B65B2220/14 , B65B2230/02

2. 发明公开

EP2603189A1 DEVICE FOR SEALING A VESSEL AND METHOD OF MANUFACTURING A SEALED VESSEL 有权转让
标题翻译：装置用于船舶密封并产生一个密封容器方法
公开(公告)号：EP2603189A1
公开(公告)日：2013-06-19
申请号：EP11740674.4
申请日：2011-08-08
申请人： Arte Corporation
发明人： SCHUETZ, Andreas , KAKIUCHI, Makoto , SHIMAZAKI, Seiji , MATSUDA, Teruo
IPC分类号： A61J1/20 , A61M5/24 , A61M5/31
CPC分类号： A61J1/2096 , A61J1/065 , A61J1/2031 , A61J1/2093 , A61M5/284 , A61M5/31511 , A61M2005/3123 , B65B3/003 , B65B2220/14 , B65B2230/02
摘要： A device for sealing a vessel, in particular a cartridge (7) or a test-tube for accommodating a freeze-dried pharmaceutical product (S), wherein the vessel (1) comprises at its opening end (3) an opening edge (4) and an adjoining longitudinal portion (5) with an evenly formed inner cross section, including a front plunger (2) to be positioned inside the vessel (1) at the longitudinal portion (5), is characterized in that the front plunger (2) is configured to be positioned in the vessel (1) in a sealing state, in which the front plunger (2) is fully inserted in the vessel (1), or in an exchange state, in which the front plunger (2) is inserted partly in the vessel (1) and partly protrudes over the opening edge (4) of the vessel (1), wherein the front plunger (2) comprises sealing means that are configured to seal the inside of the vessel (1) against the outside when the front plunger (2) is positioned in the sealing state, and one or more communicating grooves (2i) that are configured to place the inside and outside of the vessel (1) in communication with each other when the front plunger (2) is positioned in the exchange state. Furthermore, a method of manufacturing a sealed vessel (1) is disclosed.
摘要翻译：一种用于密封容器的装置，特别是盒（7）或试管用于容纳冻干药物产品（S），worin所述容器（1）在其开口端部（3）包括以开口边缘（4 ），以及相邻的纵向部分（5），其具有均匀地形成的内横截面，其包括前柱塞（2）至（1）在纵向部分（5）中做了前柱塞特点将容器内被定位（2- ）被配置在一密封状态的容器（1），其中，所述前柱塞（2）在容器（1）被完全插入到被定位，或者在交换状态中，其中所述前柱塞（2）是在容器部分地插入（1）和部分地突出于开口边缘（4）的容器（1），worin前柱塞（2）包括密封bedeutet，DASS被构造成密封所述容器（1）抵靠的内当外界前柱塞（2）被定位在所述密封状态，和一个或多个连通槽（2I）也被配置以放置容器（1）的内部和外部连通海誓山盟当前柱塞（2）在交换状态下被定位。进一步，制造密封容器（1）的方法是游离缺失光盘。

3. 发明授权

EP2812053B1 DEVICE FOR ACCOMMODATING A FREEZE-DRIED PHARMACEUTICAL PRODUCT AND METHOD OF MANUFACTURING A SEALED VESSEL ACCOMMODATING A FREEZE-DRIED PHARMACEUTICAL PRODUCT 有权转让
标题翻译：用于容纳冷冻药物产品的装置和制造冷冻药物产品的密封容器的方法
公开(公告)号：EP2812053B1
公开(公告)日：2017-10-18
申请号：EP13708361.4
申请日：2013-02-11
申请人： Arte Corporation
发明人： KAKIUCHI, Makoto , SHIMAZAKI, Seiji , MATSUDA, Teruo , SCHUETZ, Andreas
IPC分类号： A61M5/28 , A61M5/31 , B65B3/00 , A61J1/20
CPC分类号： B65D83/005 , A61J1/20 , A61J3/00 , A61M5/284 , A61M2005/3123 , B65B3/003 , B65B7/2821 , B65B63/08 , B65B2220/14 , B65B2230/02

4. 发明公开

EP2812053A1 DEVICE FOR ACCOMODATING A FREEZE-DRIED PHARMACEUTICAL PRODUCT AND METHOD OF MANUFACTURING A SEALED VESSEL ACCOMODATING A FREEZE-DRIED PHARMACEUTICAL PRODUCT 有权转让
标题翻译：设备用于接收冻干药物产品和方法生产的密封容器，用于接收冻干药剂产品
公开(公告)号：EP2812053A1
公开(公告)日：2014-12-17
申请号：EP13708361.4
申请日：2013-02-11
申请人： Arte Corporation
发明人： KAKIUCHI, Makoto , SHIMAZAKI, Seiji , MATSUDA, Teruo , SCHUETZ, Andreas
IPC分类号： A61M5/28 , A61M5/31
CPC分类号： B65D83/005 , A61J1/20 , A61J3/00 , A61M5/284 , A61M2005/3123 , B65B3/003 , B65B7/2821 , B65B63/08 , B65B2220/14 , B65B2230/02
摘要： A device for accommodating a freeze-dried pharmaceutical product (S) for reconstitution, comprising: a vessel (1) having at its opening end (3) an opening edge (4) and an adjoining longitudinal portion (5) with an evenly formed inner cross section, a front plunger (2) to be positioned inside the vessel (1) at the longitudinal portion (5), wherein the front plunger (2) is configured to be positioned inside the vessel (1) in a sealing state, in which the front plunger (2) is fully inserted in the vessel (1), or in an exchange state, in which the front plunger (2) is inserted partly in the vessel (1) and partly protrudes over the opening edge (4) of the vessel (1), and wherein the front plunger (2) comprises sealing means that are configured to seal the inside of the vessel (1) against the outside when the front plunger (2) is positioned in the sealing state, and one or more communicating grooves (2i) that are configured to place the inside and outside of the vessel (1) in communication with each other when the front plunger (2) is positioned in the exchange state, is characterized in that the sealing means are dimensioned and/or structured in such a way that the front plunger (2), when an underpressure of predefined strength is applied to the outer environment of the vessel (1), is caused to move inside the vessel (1) toward its opening end (3). Furthermore, a method of manufacturing a sealed vessel (1) accommodating a freeze-dried pharmaceutical product (S) is disclosed.
摘要翻译：一种用于容纳冻干药物产品（S），用于重构的装置，包括：（1）具有在其开口端（3）至开口边缘（4）和上相邻纵向部分的容器（5），其具有均匀地形成帧内横截面，前柱塞（2）在（5）的纵向部分的容器（1）内被定位，worin前柱塞（2）被配置在容器内，以被定位（1）在密封状态下，在其中前柱塞（2）被完全插入在容器（1），或在交换状态中，其中所述前柱塞部分地插入在所述容器（1）（2）和部分地突出于开口边缘（4）所述容器（1），和worin前柱塞（2）包括密封bedeutet，DASS被构造成密封所述容器（1）相对于外部的内侧当前柱塞（2）在密封状态定位，并且一个或多个连通槽（2I）也被配置为放置容器（1）的内部和外部连通瓦特第i个海誓山盟当前柱塞（2）在交换状态下被定位，在DASS特点模具密封装置的尺寸和/或构造在寻求一种方式做了前柱塞（2）当一个预定义的强度的压力下施加到所述容器的外部环境（1）造成的容器（1）朝向其开口端部（3）内移动。进一步，在制造（1）容纳冻干药物产品（S）的密封容器的制造方法是游离缺失光盘。

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