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    • 1. 发明公开
    • Assay device comprising serial reaction zones
    • Testvorrichtung mit seriellen Reaktionszonen
    • EP2269737A2
    • 2011-01-05
    • EP10166665.9
    • 2010-06-21
    • Amic AB
    • Mendel-Hartvig, IbRundström, GerdÖhman, Per Ove
    • B01L3/00
    • B01L3/5027B01L2200/16B01L2300/0681B01L2300/0816B01L2300/0864B01L2300/126B01L2400/0406B01L2400/0409B01L2400/0418B01L2400/0475
    • There is disclosed an analysis device comprising a substrate having at least one sample addition zone (A), at least one sink (C), and at least one flow path (B) connecting the at least one sample addition zone (A) and the at least one sink (C), wherein the at least one flow path (B) comprises projections substantially vertical to the surface of said substrate and having a height (H), diameter (D) and reciprocal spacing (t1,t2) such that lateral capillary flow of a liquid sample is achieved, wherein the device comprises at least two reaction zones in series, wherein each reaction zone is adapted to facilitating measurement of a response originating from one and the same analyte, and wherein the at least two reaction zones are positioned to allow calculation of the concentration of at least one analyte. Advantages include that a more accurate value can be calculated, variations are reduced, and an estimation of the uncertainty of the response can be calculated.
    • 公开了一种分析装置,其包括具有至少一个样品添加区(A),至少一个沉(C)和至少一个流路(B)的基板,所述至少一个流路(B)连接至少一个样品添加区(A)和 至少一个水槽(C),其中所述至少一个流动路径(B)包括基本上垂直于所述衬底的表面并具有高度(H),直径(D)和往复间隔(t1,t2)的突起,使得 实现液体样品的侧向毛细管流动,其中该装置包括至少两个串联的反应区,其中每个反应区适于促进来自一个和相同分析物的响应的测量,并且其中该至少两个反应区 被定位成允许计算至少一种分析物的浓度。 优点包括可以计算更准确的值,降低变化,并且可以计算出响应的不确定度的估计。