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1. 发明公开

EP4373404A1 SPARSE BACKGROUND MEASUREMENT AND CORRECTION FOR IMPROVING IMAGING 审中-实审
公开(公告)号：EP4373404A1
公开(公告)日：2024-05-29
申请号：EP21756106.7
申请日：2021-07-23
申请人： Accuray, Inc.
发明人： BAI, Chuanyong , ZAHN, Robert , GAGNON, Daniel , JAIN, Amit , YU, Zhicong , PREKAS, Georgios
IPC分类号： A61B6/02 , A61B6/00 , A61N5/10 , H04N25/62
CPC分类号： A61B6/585 , A61B6/02 , A61N2005/105420130101 , A61B6/5258 , A61N2005/106120130101 , A61B6/5235 , A61B6/4085 , A61N5/1049

2. 发明公开

EP4364097A1 ANCHORED KERNEL SCATTER ESTIMATE 审中-实审
公开(公告)号：EP4364097A1
公开(公告)日：2024-05-08
申请号：EP21746257.1
申请日：2021-06-30
申请人： Accuray, Inc.
发明人： SHEA, Jacob , BAI, Chuanyong
IPC分类号： G06T11/00
CPC分类号： G06T11/005 , G06T2211/45220230801

3. 发明公开

EP3307385A1 VERIFICATION OF LEAF POSITIONS FOR MULTI-LEAF COLLIMATOR USING MULTIPLE VERIFICATION SYSTEMS 审中-公开
标题翻译：用多重验证系统验证多叶落地平台的叶位
公开(公告)号：EP3307385A1
公开(公告)日：2018-04-18
申请号：EP16713703.3
申请日：2016-03-21
申请人： Accuray, Inc.
发明人： CHAPPELOW, Jonathan Cecil , JORDAN, Petr , MAURER,Calvin , SINGH, Sarbjit , FITTING, Andrew W. , MYRONENKO, Andriy , GAO, Jian
IPC分类号： A61N5/10 , G21K1/04
CPC分类号： A61N5/1049 , A61N5/1045 , A61N5/1048 , A61N2005/1054 , A61N2005/1074 , G06T7/0012 , G21K1/046
摘要： A method includes determining a first estimate of leaf positions for a plurality of leaves of a multi-leaf collimator (MLC) in a reference coordinate space based on an image generated by an image-based aperture verification system, wherein the leaf positions for the plurality of leaves define an aperture for the MLC. The method further includes determining a second estimate of the leaf positions for the plurality of leaves in the reference coordinate space based on data from an additional source. The method further includes verifying the leaf positions for the plurality of leaves based on comparing the first estimate to the second estimate, wherein the leaf positions are verified if the first estimate deviates from the second estimate by less than a threshold value.

4. 发明公开

EP2326254A4 SEVEN OR MORE DEGREES OF FREEDOM ROBOTIC MANIPULATOR HAVING AT LEAST ONE REDUNDANT JOINT 有权
公开(公告)号：EP2326254A4
公开(公告)日：2017-11-08
申请号：EP09813418
申请日：2009-08-12
申请人： ACCURAY INC
发明人： NAYLOR MICHAEL P , SAYEH SOHAIL
IPC分类号： A61B17/00 , A61B34/00 , A61B34/30 , A61N5/10
CPC分类号： A61N5/1049 , A61B6/04 , A61B34/30 , A61B34/71 , A61B2034/305 , A61N5/1083 , A61N2005/1061
摘要： A robotic treatment delivery system including a linear accelerator (LINAC), and a robotic manipulator coupled to the LINAC. The robotic manipulator is configured to move the LINAC along seven or more degrees of freedom, at least one of the seven degrees of freedom being a redundant degree of freedom.

5. 发明公开

EP3195902A1 GANTRY IMAGE GUIDED RADIOTHERAPY SYSTEM AND RELATED TREATMENT DELIVERY METHODS 有权
标题翻译： GANTRY图像引导放射治疗系统和相关的治疗传递方法
公开(公告)号：EP3195902A1
公开(公告)日：2017-07-26
申请号：EP17158986.4
申请日：2011-02-23
申请人： Accuray, Inc.
发明人： MAURER, Calvin R., Jr.
IPC分类号： A61N5/10 , A61N5/00
CPC分类号： A61N5/1039 , A61B5/0035 , A61B5/0059 , A61B5/055 , A61B6/025 , A61B6/032 , A61B6/06 , A61B6/4014 , A61B6/4085 , A61B6/4435 , A61B6/4452 , A61B6/488 , A61N5/10 , A61N5/1037 , A61N5/1042 , A61N5/1048 , A61N5/1049 , A61N5/1065 , A61N5/1067 , A61N5/1081 , A61N5/1082 , A61N2005/1061 , A61N2005/1062 , A61N2005/1092 , G01N2223/308
摘要： Systems, methods, and related computer program products for image- guided radiation treatment (IGRT) are described. Provided according to one preferred embodiment is an IGRT apparatus including a barrel-style rotatable gantry structure that provides high mechanical stability, versatility in radiation delivery, and versatility in target tracking. Methods for treatment radiation delivery using the IGRT apparatus include conical non-coplanar rotational arc therapy and cono-helical non-coplanar rotational arc therapy. A radiation treatment head (MV source) and a treatment guidance imaging system including a kV imaging source are mounted to and rotatable with a common barrel-style rotatable gantry structure, or alternatively the MV and kV sources are mounted to separate barrel-style rotatable gantry structures independently rotatable around a common axis of rotation. Methods for intra-fraction target tracking in a gantry-style IGRT system based on comparisons between a pre- acquired planning image and intrafraction x-ray tomosynthesis images and/or intrafraction cone beam CT (CBCT) images are also described.
摘要翻译：描述了用于图像引导放射治疗（IGRT）的系统，方法和相关的计算机程序产品。根据一个优选实施例提供的是包括筒式可旋转台架结构的IGRT设备，其提供高机械稳定性，辐射输送的多功能性以及目标跟踪的多功能性。使用IGRT装置治疗放射线输送的方法包括锥形非共面旋转弧疗法和cono-螺旋非共面旋转弧疗法。包括kV成像源的放射治疗头（MV源）和治疗引导成像系统安装到共同的桶形可旋转门架结构并且可与其一起旋转，或者可选地，MV和kV源被安装成分离桶形可旋转机架结构可独立地围绕共同的旋转轴线旋转。还描述了用于基于预先采集的计划图像和片内X射线断层合成图像和/或片内锥形束CT（CBCT）图像之间的比较的机架式IGRT系统内的片内目标跟踪的方法。

6. 发明公开

EP2665519A2 RADIATION TREATMENT DELIVERY SYSTEM WITH RING GANTRY 有权转让
标题翻译：系统ZUR VERABREICHUNG EINER STRAHLENTHERAPIE MIT EINEM RING-GANTRY
公开(公告)号：EP2665519A2
公开(公告)日：2013-11-27
申请号：EP12700904.1
申请日：2012-01-10
申请人： Accuray, Inc.
发明人： MAURER, Calvin R. JR. , LINDQUIST, Eric P.
IPC分类号： A61N5/10 , A61N5/00
CPC分类号： A61B6/032 , A61B5/055 , A61B6/4085 , A61B6/4405 , A61N5/10 , A61N5/1045 , A61N5/1048 , A61N5/1049 , A61N5/1067 , A61N5/1081 , A61N5/1082 , A61N2005/0633 , A61N2005/1055 , A61N2005/1061 , A61N2005/1062 , A61N2005/1063
摘要： Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. For one preferred embodiment, an IGRT apparatus is provided comprising a ring gantry having a central opening and a radiation treatment head coupled to the ring gantry that is rotatable around the central opening in at least a 180 degree arc. For one preferred embodiment, the apparatus further comprises a gantry translation mechanism configured to translate the ring gantry in a direction of a longitudinal axis extending through the central opening. Noncoplanar radiation treatment delivery can thereby be achieved without requiring movement of the patient. For another preferred embodiment, an independently translatable 3D imaging device distinct from the ring gantry is provided for further achieving at least one of pre-treatment imaging and setup imaging of the target tissue volume without requiring movement of the patient.
摘要翻译：描述了用于图像引导辐射治疗（IGRT）的系统，方法和相关计算机程序产品。对于一个优选实施例，提供了一种IGRT装置，其包括具有足够大的中心开口的环形台架，该中心开口足以容纳沿着纵向轴线定位并延伸穿过其中的患者的身体，以及构造成将环形台架倾斜到多个的台架倾斜机构相对于纵向轴线具有不同的倾斜角度。辐射治疗头被联接到环形台架并且可以以至少180度的弧度围绕所述中心开口旋转。放射治疗头机械耦合到环形台架，使得辐射治疗头相对于环形台架向内朝向中心开口延伸的距离是动态可控的。

7. 发明公开

EP2349480A4 SEQUENTIAL OPTIMIZATIONS FOR TREATMENT PLANNING 审中-公开
标题翻译：治疗计划顺序优化
公开(公告)号：EP2349480A4
公开(公告)日：2012-07-25
申请号：EP09822371
申请日：2009-08-28
申请人： ACCURAY INC
发明人： KILBY WARREN D , ORR GREGORY L , LESSARD ETIENNE , SIMS COLIN , DOOLEY JOHN R , MAURER CALVIN R JR , WEST JAY B
IPC分类号： A61N5/10
CPC分类号： A61N5/1031 , A61N5/10 , A61N5/103 , A61N5/1042 , A61N5/1083

8. 发明公开

EP1793895A4 FLEXIBLE TREATMENT PLANNING 审中-公开
标题翻译：灵活的治疗计划
公开(公告)号：EP1793895A4
公开(公告)日：2011-06-15
申请号：EP05805897
申请日：2005-09-30
申请人： ACCURAY INC
发明人： DOOLEY JOHN R , WANG JIN-WU J , BODDULURI RADHIKA MOHAN , WEST JAY B
IPC分类号： A61N5/10
CPC分类号： A61N5/1031

9. 发明公开

EP1793734A4 DYNAMIC TRACKING OF MOVING TARGETS 有权转让
标题翻译： DYNAMISCHE VERFOLGUNG VON BEWEGLICHEN ZIELEN
公开(公告)号：EP1793734A4
公开(公告)日：2009-09-23
申请号：EP05791522
申请日：2005-08-22
申请人： ACCURAY INC
发明人： THOMSON EUAN , DOOLEY JOHN ROBINSON , KUDUVALLI GOPINATH , WANG JAMES , EARNST ERIC , RAANES CHRIS
IPC分类号： A61B5/05
CPC分类号： A61N5/1037 , A61B5/055 , A61B5/113 , A61B6/032 , A61B6/037 , A61B6/12 , A61B6/5217 , A61B34/20 , A61B90/36 , A61B2017/00694 , A61B2034/105 , A61B2034/2065 , A61B2090/101 , A61B2090/367 , A61B2090/3762 , A61N5/1039 , A61N5/1049 , A61N5/1064 , A61N5/1067 , A61N2005/1052 , A61N2005/1055 , A61N2005/1061 , A61N2005/1062
摘要： Treatment targets such as tumors or lesions, located within an anatomical region that undergoes motion (which may be periodic with cycle P), are dynamically tracked. A 4D mathematical model is established for the non-rigid motion and deformation of the anatomical region, from a set of CT or other 3D images. The 4D mathematical model relates the 3D locations of part(s) of the anatomical region with the targets being tracked, as a function of the position in time within P. Using fiducial-less non-rigid image registration between pre-operative DRRs and intra-operative x-ray images, the absolute position of the target and/or other part(s) of the anatomical region is determined. The cycle P is determined using motion sensors such as surface markers. The radiation beams are delivered using: 1) the results of non-rigid image registration; 2) the 4D model; and 3) the position in time within P.
摘要翻译：位于处于运动的解剖区域（可能与周期P周期性）的肿瘤或病变的治疗靶点被动态跟踪。建立了一个4D数学模型，用于从一组CT或其他3D图像中解剖区域的非刚性运动和变形。 4D数学模型将解剖区域的部分的3D位置与正在跟踪的目标相关联，作为P内时间位置的函数。使用在手术前DRR和intra之间的无基准的非刚性图像配准手术X射线图像，确定解剖区域的目标和/或其他部分的绝对位置。周期P使用诸如表面标记的运动传感器来确定。使用以下方式传送辐射束：1）非刚性图像配准的结果; 2）4D模型; 和3）时间内的位置。

10. 发明公开

EP1773198A4 DRR GENERATION USING A NON-LINEAR ATTENUATION MODEL 审中-公开
标题翻译：与非线性衰减模型DRR GENERATION
公开(公告)号：EP1773198A4
公开(公告)日：2009-08-19
申请号：EP05735607
申请日：2005-04-01
申请人： ACCURAY INC
发明人： FU DONGSHAN , KUDUVALLI GOPINATH
IPC分类号： A61B6/04
CPC分类号： G06T11/008
摘要： A method and system are presented for generating a DRR of an anatomical region so that the visibility within the DRR of one or more skeletal reference structures is enhanced. 3D scan data, which have been obtained from a 3D scan of the object conducted at a 3D scan energy level, are provided. The 3D scan data are modified to compensated for a difference between the ratio of bone-to-tissue attenuation at the 3D scan energy level, and the ratio of bone-to-tissue attenuation at the intensity of the imaging beam which the DRR emulates. The modified 3D scan data are related to the raw 3D scan data by a non-linear, exponential relationship. A plurality of hypothetical rays are cast through the modified 3D scan data, from the known geometry of the imaging beam. The 3D scan data are integrated along each hypothetical ray, and the integrated values are projected onto an imaging plane.

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