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1. 发明授权

EP1298124B1 Method For the Preparation of Citalopram 有权
标题翻译：一种用于西酞普兰的制备方法
公开(公告)号：EP1298124B1
公开(公告)日：2007-02-28
申请号：EP02028326.3
申请日：1999-10-25
申请人： H. LUNDBECK A/S
发明人： Rock, Michael Harold , Petersen, Hans , Ellegaard, Peter
IPC分类号： C07C255/56 , C07D307/87
CPC分类号： C07D307/87

2. 发明公开

EP1576969A1 A wound care device 审中-公开
标题翻译： Artikel zur Wundbehandlung
公开(公告)号：EP1576969A1
公开(公告)日：2005-09-21
申请号：EP05011920.5
申请日：2002-12-19
申请人： COLOPLAST A/S
发明人： Juel-Friis, Gitte , Richter-Friis, Tine , Larsen, Truels Sterm
IPC分类号： A61L15/44 , A61L26/00
CPC分类号： A61L26/0066 , A61L15/44 , A61L2300/41 , A61L2300/434 , A61L2300/602
摘要： A wound care device for local treatment of pain in a wound comprising an active pain relieving composition, wherein said composition is an anti-inflammatory pain killing agent. The wound care device is suitable for treatment of pain in open wounds. The device may be in the form of a wound dressing, and the pain relieving composition may be delivered to the wound through a controlled release system.
摘要翻译：提供了用于局部治疗伤口疼痛的伤口护理装置。该装置包括主动止痛组合物，其还可以是抗炎剂。伤口护理装置适用于治疗开放性伤口的疼痛。该装置可以包括少量减轻疼痛的组合物，其有效地缓解伤口的疼痛，而不会导致任何全身作用。该装置可以是伤口敷料的形式，并且该疼痛消除组合物可以通过控制释放系统输送到伤口。

3. 发明公开

EP1440691A3 Treatment of neurotic disorders 审中-公开
标题翻译：神经错乱的治疗
公开(公告)号：EP1440691A3
公开(公告)日：2004-08-25
申请号：EP04007522.8
申请日：2000-07-07
申请人： H.Lundbeck A/S
发明人： Sanchez, Connie , Hogg Willigers, Sandra
IPC分类号： A61K31/343 , A61P25/22
CPC分类号： A61K31/343 , Y10S514/962
摘要： Use of the escitalopram or a pharmaceutically acceptable salt thereof for the preparation of a medicament useful in the treatment of panic attacks.

4. 发明公开

EP1440691A2 Treatment of neurotic disorders 审中-公开
标题翻译：治疗神经障碍
公开(公告)号：EP1440691A2
公开(公告)日：2004-07-28
申请号：EP04007522.8
申请日：2000-07-07
申请人： H.Lundbeck A/S
发明人： Sanchez, Connie , Hogg Willigers, Sandra
IPC分类号： A61K31/343 , A61P25/22
CPC分类号： A61K31/343 , Y10S514/962
摘要： Use of the escitalopram or a pharmaceutically acceptable salt thereof for the preparation of a medicament useful in the treatment of panic attacks.
摘要翻译：依他普仑或其药学上可接受的盐用于制备用于治疗恐慌发作的药物的用途。

5. 发明授权

EP1299384B1 INDOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS 有权
标题翻译： FOR USE IN CNS障碍的治疗的吲哚衍生物
公开(公告)号：EP1299384B1
公开(公告)日：2004-03-24
申请号：EP01940242.9
申请日：2001-06-13
申请人： H. Lundbeck A/S
发明人： BANG-ANDERSEN, Benny , LARSEN, Krestian , KEHLER, Jan
IPC分类号： C07D417/14 , A61K31/38 , A61K31/395 , A61K31/4045 , A61K31/4523 , A61K31/496 , A61P25/06 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28
CPC分类号： C07D417/12 , C07D417/14
摘要： The present invention relates to dopamine and serotonin receptor ligands having the general formula (I) wherein the meanings of Y, Z, W, n, m, X and R1-R12 are as given in the claims and the description. The compounds of the invention are useful in the treatment of certain psychiatric and neurological disorders, i. e. schizophrenia and other psychoses, anxiety disorders, depression, migraine, cognitive disorders, attention deficit hyperactivity disorder (ADHD) and sleep improvement.

6. 发明公开

EP1613303A1 SUBSTITUTED P-DIAMINOBENZENE DERIVATIVES 审中-公开
标题翻译：替代对二氨基苯甲酸衍生物
公开(公告)号：EP1613303A1
公开(公告)日：2006-01-11
申请号：EP04721472.1
申请日：2004-03-18
申请人： H. LUNDBECK A/S
发明人： KHANZHIN, Nikolay , ROTTLÄNDER, Mario , RITZEN, Andreas , WATSON, William, Patrick
IPC分类号： A61K31/381 , A61K31/27 , C07C271/28 , C07D333/02 , C07D213/02 , A61P25/00
CPC分类号： C07D333/28 , C07C211/52 , C07C217/84 , C07C217/86 , C07C217/88 , C07C233/43 , C07C233/44 , C07C237/04 , C07C237/24 , C07C271/28 , C07C317/32 , C07C323/32 , C07C329/06 , C07C2601/02 , C07C2601/08 , C07D213/38 , C07D213/61 , C07D213/643 , C07D231/20 , C07D239/22 , C07D239/26 , C07D261/08 , C07D295/145 , C07D307/52 , C07D307/81 , C07D317/58 , C07D333/20 , C07D333/34 , C07D333/56 , C07D333/58 , C07D409/12
摘要： The present invention relates to aniline derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
摘要翻译：本发明涉及通式I的苯胺衍生物或其药学上可接受的盐及其用途。

7. 发明公开

EP1478311A1 AN OSTOMY APPLIANCE 有权
标题翻译：一个家庭电器
公开(公告)号：EP1478311A1
公开(公告)日：2004-11-24
申请号：EP03706338.5
申请日：2003-02-26
申请人： COLOPLAST A/S
发明人： POULSEN, Lars, Bo , NIELSEN, Per, Ole
IPC分类号： A61F5/441
CPC分类号： A61F5/441
摘要： An ostomy appliance comprising a front wall and a rear wall of flexible material forming a bag, the rear wall having an opening into the bag by which waste material can enter the bag, said bag having two or more vents through which gas may escape from the bag and having a filter device covering each vent, said filter device being provided with gas inlet and outlet openings in communication with at least one filter body, the arrangement being so that in use gas flows through the filter device from the inlet opening to the outlet opening, such gas flow being confined to said filter body, wherein the ostomy appliance is provided with at least two independent filter devices having separate inlet openings communicating with the inner space of the bag and wherein the inlet openings of the filter devices are located near the border of the bag shows improved resistance against blocking of the inlet opening of filter.
摘要翻译：一种造口术器具，包括形成袋的前壁和后壁的柔性材料，后壁具有进入袋中的开口，废料可通过该开口进入袋中，所述袋具有两个或更多个通气口，气体可通过该通气口从并且具有覆盖每个通风口的过滤器装置，所述过滤器装置设置有与至少一个过滤器主体连通的气体入口和出口开口，该结构使得在使用中气体从入口开口流过过滤器装置到出口所述气体流被限制在所述过滤体上，其中所述造口术器具设置有至少两个独立的过滤装置，所述独立的过滤装置具有与所述袋的内部空间连通的单独的入口开口，并且其中所述过滤装置的入口开口位于袋的边界显示出改进的阻止过滤器入口开口的阻力。

8. 发明公开

EP1440690A3 Treatment of neurotic disorders 审中-公开
公开(公告)号：EP1440690A3
公开(公告)日：2004-08-18
申请号：EP04007521.0
申请日：2000-07-07
申请人： H.Lundbeck A/S
发明人： Sanchez, Connie , Hogg Willigers, Sandra
IPC分类号： A61K31/343 , A61P25/22
CPC分类号： A61K31/343 , Y10S514/962
摘要： Use of the escitalopram or a pharmaceutically acceptable salt thereof for the preparation of a medicament useful in the treatment of post traumatic stress disorder.

9. 发明公开

EP1412341A1 PROCESS FOR THE PREPARATION OF RACEMIC CITALOPRAM AND/OR S- OR R-CITALOPRAM BY SEPARATION OF A MIXTURE OF R- AND S-CITALOPRAM 有权
标题翻译：用于生产外消旋西酞普兰和/或S或R西酞普兰进行分离R和S西酞普兰的混合物
公开(公告)号：EP1412341A1
公开(公告)日：2004-04-28
申请号：EP02742848.1
申请日：2002-06-25
申请人： H. Lundbeck A/S
发明人： HUMBLE, Rikke, Eva , CHRISTENSEN, Troels, Volsgaard , ROCK, Michael, Harold , NIELSEN, Ole , PETERSEN, Hans , DANCER, Robert
IPC分类号： C07D307/87
CPC分类号： C07D307/87
摘要： The invention relates to a process for the preparation of racemic citalopram free base or an acid addition salt thereof and/or R- or S-citalopram as the free base or an acid addition salt thereof by separation of a mixture of R- and S-citalopram with more than 50% of one of the enantiomers into a fraction consisting of racemic citalopram and/or a fraction of S-citalopram or R-citalopram characterized in that i) citalopram is precipitated from a solvent as the free base or as an acid addition salt thereof; ii) the precipitate formed is separated from the mother liquor; iia) if the precipitate is crystalline it is optionally recrystallised one or more times to form racemic citalopram, and then optionally converted into an acid addition salt thereof; iib) if the precipitate is not crystalline, steps i) and ii) are optionally repeated until a crystalline precipitate is obtained and the crystalline precipitate is recrystallised one or more times to form racemic citalopram, and then optionally converted into an acid addition salt thereof; iii) the mother liquor is optionally subjected to further purification and S-citalopram or R-citalopram is isolated from the mother liquor and optionally converted into an acid addition salt thereof.

10. 发明公开

EP1305307A1 INDOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS 有权
标题翻译：吲哚衍生物CNS病症的治疗，可以使用
公开(公告)号：EP1305307A1
公开(公告)日：2003-05-02
申请号：EP01960182.2
申请日：2001-07-17
申请人： H. Lundbeck A/S
发明人： FELDING, Jakob , BANG-ANDERSEN, Benny , SMITH, Garrick, Paul , ANDERSEN, Kim
IPC分类号： C07D401/14 , C07D403/14 , A61K31/4045 , A61K31/4523 , A61P25/06 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28
CPC分类号： C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/14
摘要： The present invention relates to dopamine and serotonin receptor ligands having the general formula (I) wherein the meanings of R1-R9, W, n and X are as given in the claims and the description. The compounds of the invention are useful in the treatment of certain psychiatric and neurological disorders, i.e. schizophrenia, other psychoses, anxiety disorders, depression, migraine, cognitive disorders, ADHD and sleep improvement.

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