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    • 7. 发明公开
    • DEVICE FOR DETECTING MOLECULES
    • EP4455667A1
    • 2024-10-30
    • EP24172222.2
    • 2024-04-24
    • Viscera Technologies Ltd
    • HOLLAMBY, HenryQUIGLEY, Ryan
    • G01N33/543G01N33/94
    • G01N33/54388G01N33/946
    • There is disclosed a lateral flow test device in which a conjugate pad comprises a mobilisable conjugated analyte comprising one or more analyte molecules conjugated to a detectable label. A first test region comprises an immobilised analyte-binding molecule defining a first binding site, or the conjugate pad comprises a mobilisable analyte-binding molecule and the first test region comprises an immobilised capture molecule for immobilising the analyte-binding molecule, wherein the immobilised capture molecule defines a first binding site, or the conjugate pad comprises a mobilisable analyte-binding molecule and the first test region comprises an immobilised analyte-binding molecule defining a first binding site. A second test region comprises an immobilised conjugated-analyte-binding molecule which binds the conjugated analyte and does not bind unconjugated analyte molecules, and defines a second binding site. The number of molecules of the conjugated analyte is less than or equal to the number of second binding sites. There is also disclosed methods of detecting the presence of an analyte molecule in a test sample and of diagnosing a disease or condition, a computer-implemented method of detecting the presence of an analyte molecule in a test sample, and a kit.