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1. 发明公开

EP4321521A1 FRACTIONATION OF PROTEINS FOR PROTEOMICS 审中-公开
公开(公告)号：EP4321521A1
公开(公告)日：2024-02-14
申请号：EP22190074.9
申请日：2022-08-11
申请人： PreOmics GmbH
发明人： KULAK, Nils A
IPC分类号： C07K1/14 , C07K1/30 , C07K1/36
摘要： The present invention relates to a method of fractionating a sample comprising proteins, polypeptides and/or peptides, said method comprising (a) performing a first change of physicochemical conditions of said sample, wherein said first change establishes precipitating conditions for said proteins, polypeptides and/or peptides, but does not establish denaturing conditions for said proteins, polypeptides and/or peptides; and (b) performing one or both of the following (i) and (ii): (i) adding solid particulate matter to said sample; and (ii) performing said method in a vessel with a rough surface; wherein steps (a) and (b) can be effected concomitantly or in any order and yield a first fraction of proteins, polypeptides and/or peptides as a first precipitate on said particulate matter and/or on said inhomogeneous surface, and a second fraction of proteins, polypeptides and/or peptides remaining in a supernatant; and (c) subjecting said first precipitate to a second change of physicochemical conditions which are capable of solubilizing a part of said first precipitate, thereby obtaining a third fraction remaining precipitated and a fourth fraction in solution.

2. 发明公开

EP4202440A1 PROTEOMICS-BASED STRATIFICATION OF ACUTE MYELOID LEUKAEMIA 无效
公开(公告)号：EP4202440A1
公开(公告)日：2023-06-28
申请号：EP21216747.2
申请日：2021-12-22
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. , Johann-Wolfgang-Goethe-Universität Frankfurt am Main , Deutsches Krebsforschungszentrum Heidelberg Stiftung des öffentlichen Rechts (DKFZ)
发明人： Mann, Matthias , Jayavelu, Ashok Kumar , Urlaub, Henning , Oellerich, Thomas , Wolf, Sebastian , Serve, Hubert , Büttner, Florian
IPC分类号： G01N33/574
摘要： The present invention relates to a method of identifying sub-forms of acute myeloid leukemia (AML), said method comprising (a) determining protein expression levels of a plurality of proteins in a cohort of patients suffering from AML; and (b) classifying said patients according to said protein expression levels; thereby obtaining classes of patients which define sub-forms of AML.

3. 发明公开

EP4171045A1 PRODUCTION METHOD AND DEVICE FOR MULTIMEDIA WORKS, AND COMPUTER-READABLE STORAGE MEDIUM 审中-实审
公开(公告)号：EP4171045A1
公开(公告)日：2023-04-26
申请号：EP21862207.4
申请日：2021-08-11
申请人： Lemon Inc.
发明人： CAI, Xiaojuan , SONG, Xuchen , LI, Gen , ZHONG, Haoyuan , MO, Weishu , LI, Hui
IPC分类号： H04N21/44 , G06F16/14 , G06K9/62 , G06N3/02
摘要： A production method and device for multimedia works, and a computer-readable storage medium. The method comprises: acquiring a target audio and at least one piece of multimedia information, calculating the degree of match between the target audio and the multimedia information, sorting multimedia information on the basis of the degree of match in a descending order, assigning top-ranking multimedia information as target multimedia information; calculating the image quality of each image in the target multimedia information, sorting every image of the target multimedia information on the basis of image quality in a descending order, assigning the top-ranking images as target images; and synthesizing a multimedia work on the basis of the target images and the target audio. The method allows the acquisition of high-definition multimedia works in which the video content and background music match with each other, and reduces the time costs and costs of learning that a user spends on video editing.

4. 发明公开

EP4171017A1 VIDEO GENERATION AND PLAYING METHOD AND APPARATUS, AND ELECTRONIC DEVICE AND STORAGE MEDIUM 审中-实审
公开(公告)号：EP4171017A1
公开(公告)日：2023-04-26
申请号：EP21850417.3
申请日：2021-07-21
申请人： BEIJING BYTEDANCE NETWORK TECHNOLOGY CO., LTD.
发明人： LIU, Ji , ZHANG, Hong , LIU, Yinzhu , SUN, Tao , ZHOU, Lin , SHEN, Hong
IPC分类号： H04N5/262
摘要： Provided are a video generation and playing method and apparatus, and an electronic device and a computer-readable storage medium, which relate to the field of video processing. The method comprises: acquiring a first video; executing Gaussian blur special effect processing on the first video to obtain a second video; superimposing an additional dynamic effect onto the second video to generate a third video, wherein the additional dynamic effect is a dynamic image which presents related information of the first video by means of a dynamic effect; and splicing the first video and the third video to generate a fourth video, wherein an image area of the fourth video comprises a first image area and a second image area, the first image area being used for presenting an image of the first video, and the second image area being used for presenting an image of the third video. By means of the present disclosure, the viewing experience of a user is improved.

5. 发明公开

EP4170588A2 VIDEO PHOTOGRAPHING METHOD AND APPARATUS, AND DEVICE AND STORAGE MEDIUM 审中-实审
公开(公告)号：EP4170588A2
公开(公告)日：2023-04-26
申请号：EP21867243.4
申请日：2021-08-30
申请人： Lemon Inc.
发明人： LU, Zhixiong , CHEN, Zhili
IPC分类号： G06T7/10 , G06F3/0484
摘要： A video photographing method and apparatus, and a device and a storage medium. The method is applied to a terminal device, and the terminal device comprises a camera. The method comprises: in response to an input event of selecting a target object to be segmented from a plurality of objects that are presented in a collection picture of a camera, segmenting said target object so as to obtain a target segmentation result; displaying the target segmentation result; and in response to a trigger operation of adjusting the target segmentation result, fusing the adjusted target segmentation result with a video scene to be fused, so as to generate a video.

6. 发明公开

EP4170531A1 INFORMATION PROCESSING METHOD AND APPARATUS, DEVICE, AND STORAGE MEDIUM 审中-实审
公开(公告)号：EP4170531A1
公开(公告)日：2023-04-26
申请号：EP21868538.6
申请日：2021-09-08
申请人： Beijing Zitiao Network Technology Co., Ltd.
发明人： WU, Yiying
IPC分类号： G06F21/60 , G06F21/62
摘要： Embodiments of the present disclosure provides an information processing method and apparatus, a device and a storage medium, a user is provided with a target application for publishing a creation through a terminal device, and the target application includes a first switch, and the method includes: performing a first authorization operation for a respective creation published by the user on the target application, in response to an enabling trigger operation acting on the first switch, where the first authorization operation is a target authorization operation matching the first switch; and the first authorization operation is used to represent that the user, a commenter corresponding to comment information under the respective creation published by the user on the target application, and a friend of the commenter are granted permission to view the respective creation and each comment information under the respective creation. The embodiments of the present disclosure can achieve a balance between visibility in public domain traffic scenarios and private domain traffic scenarios, and is flexible, thus meeting the personalized needs of users and improving the user experience.

7. 发明公开

EP4167254A1 FUNCTIONALIZED MAGNETS AND METHODS OF PRODUCING THEM 审中-公开
公开(公告)号：EP4167254A1
公开(公告)日：2023-04-19
申请号：EP21202190.1
申请日：2021-10-12
申请人： PreOmics GmbH
发明人： The designation of the inventor has not yet been filed
IPC分类号： H01F1/00 , H01F1/06 , G01N33/543 , G01N33/68
摘要： The present invention relates to a solid, magnetized or magnetizable composition comprising (i) a core consisting of or comprising a ferromagnetic or ferrimagnetic material; and (ii) at least one surface moiety selected from (1) a binding moiety; (2) a biomolecule; and (3) a chemically reactive moiety; wherein said moiety is covalently bound to (a) said core; or (b) a layer which is directly or indirectly attached to said core. The invention furthermore provides methods of producing such compositions and uses thereof.

8. 发明公开

EP4151738A1 RETROVIRAL TRANSDUCTION USING POLOXAMERS 审中-实审
公开(公告)号：EP4151738A1
公开(公告)日：2023-03-22
申请号：EP22204240.0
申请日：2013-02-28
申请人： Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) , Sirion Biotech GmbH
发明人： ANASTASOV, Natasa , HÖFIG, Ines , THIRION, Christian
IPC分类号： C12N15/867 , A61K48/00
摘要： The present invention relates to a method for transducing a target cell, the method comprising the step of contacting a target cell with a retroviral vector and a poloxamer having a molecular weight of 12,8 kDa to about 15 kDa. Further, the invention relates to the use of a poloxamer as defmed herein, optionally in combination with a polycationic substance as defmed herein, for transducing a target cell with a retroviral vector and a kit comprising a retroviral vector, a poloxamer as defined herein and, option ally, instructions for use.

9. 发明公开

EP4143051A1 FLEXIBLE CONNECTOR MECHANISM FOR LIGHT ELECTRIC VEHICLES 审中-实审
公开(公告)号：EP4143051A1
公开(公告)日：2023-03-08
申请号：EP21796376.8
申请日：2021-04-30
申请人： Neutron Holdings, Inc., DBA Lime
发明人： FOLEY, Nick , TITUS, Andrew , SCHECHTER, Shai
IPC分类号： B60L50/64 , B60L50/60 , B60L53/80 , B62J43/00 , B62M6/90 , H01M50/20

10. 发明公开

EP4113438A1 IMAGE CROPPING METHOD AND APPARATUS, AND DEVICE AND STORAGE MEDIUM 审中-实审
公开(公告)号：EP4113438A1
公开(公告)日：2023-01-04
申请号：EP21761230.8
申请日：2021-02-18
申请人： BEIJING BYTEDANCE NETWORK TECHNOLOGY CO., LTD.
发明人： LI, Linxing
IPC分类号： G06T7/12
摘要： Embodiments of the present application provide an image cropping method and apparatus, and a device and a storage medium. The image cropping method comprises: adjusting the size of an image in a cropping area of a cropping box under the condition that the frame of the cropping box reaches a first target position of an image display area and a dragging event of the cropping box is continuous; and when the dragging event of the cropping box is finished, displaying the image in the current cropping area of the cropping box at a second target position of the image display area according to the current size proportion of the image in the cropping area of the cropping box. The embodiments of the present application reduce the cropping operation difficulty and improve the cropping operation efficiency.

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