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1. 发明授权

EP2480204B1 TOPICAL FORMULATION FOR DIABETIC FOOT ULCERS 有权
标题翻译：局部制剂糖尿病足部溃疡
公开(公告)号：EP2480204B1
公开(公告)日：2013-11-06
申请号：EP10803276.4
申请日：2010-09-21
申请人： Vlife Sciences Technologies Pvt Ltd.
发明人： DESHPANDE, Supreet, K. , KULKARNI, Sudhir, A. , GOLLAPUDY, Reena
IPC分类号： A61P17/02 , A61K31/24 , A61K9/06
CPC分类号： A61K31/24 , A61K9/0014

2. 发明公开

EP2480204A2 TOPICAL FORMULATION FOR DIABETIC FOOT ULCERS 有权
标题翻译：局部制剂糖尿病足部溃疡
公开(公告)号：EP2480204A2
公开(公告)日：2012-08-01
申请号：EP10803276.4
申请日：2010-09-21
申请人： Vlife Sciences Technologies Pvt Ltd.
发明人： DESHPANDE, Supreet, K. , KULKARNI, Sudhir, A. , GOLLAPUDY, Reena
IPC分类号： A61K9/06 , A61K31/24
CPC分类号： A61K31/24 , A61K9/0014
摘要： This invention relates to a new topical gel formulation of the drug Esmolol hydrochloride for treatment of chronic wounds such as diabetic wounds, burn wounds, venous ulcers and pressure ulcers.

3. 发明公开

EP2444077A1 Pharmaceutical composition for treatment of diabetic complications 审中-公开
标题翻译：药剂师Zusammensetzung zur Behandlung von diabetischen Komplikationen
公开(公告)号：EP2444077A1
公开(公告)日：2012-04-25
申请号：EP12151969.8
申请日：2008-01-24
申请人： Vlife Sciences Technologies Pvt Ltd.
发明人： Kulkarni, Sudhir, A. , Gollapudy, Reena, R. , Deshpande, Supreet, K.
IPC分类号： A61K31/00 , A61K31/215 , A61P3/10
CPC分类号： A61K31/00 , A61K31/215
摘要： A method for treating diabetic complications by administration of a beta-blocker is disclosed. Diabetic complications arise from diabetes and have few or no existing treatment options. The present invention describes the use of a beta-blocker in the treatment of a diabetic. The present invention also describes the inhibition of aldose reductase, one of the chief causative factors of diabetic complications. Also provided are methods of diabetic wound healing. Compositions for treating diabetic complications, such as diabetic wounds, are disclosed. The present invention includes employing a topical formulation of a beta-blocker, having substantially no antibacterial activity, to improve the process of diabetic wound healing. The present invention also involves increasing the rate of collagen accumulation of the healing epithelialized tissue in the wound of a diabetic individual.
摘要翻译：公开了通过施用β-阻断剂治疗糖尿病并发症的方法。糖尿病并发症由糖尿病引起，很少或没有现有的治疗方案。本发明描述了β-阻断剂在治疗糖尿病的用途。本发明还描述了醛糖还原酶的抑制作用，其是糖尿病并发症的主要致病因素之一。还提供了糖尿病伤口愈合的方法。公开了用于治疗糖尿病并发症的组合物，例如糖尿病性伤口。本发明包括采用基本上没有抗菌活性的β-阻滞剂局部制剂来改善糖尿病性伤口愈合过程。本发明还涉及增加糖尿病个体伤口中愈合上皮组织的胶原蛋白积累速率。

4. 发明公开

EP2114386A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DIABETIC COMPLICATIONS 有权
标题翻译：药物组合物，糖尿病并发症的治疗
公开(公告)号：EP2114386A1
公开(公告)日：2009-11-11
申请号：EP08720107.5
申请日：2008-01-24
申请人： Vlife Sciences Technologies Pvt Ltd.
发明人： DESHPANDE, Supreet, K. , KULKARNI, Sudhir, A. , GOLLAPUDY, Reena, R.
IPC分类号： A61K31/00 , A61K31/215 , A61P3/10
CPC分类号： A61K31/00 , A61K31/215
摘要： A method for treating diabetic complications by administration of a beta-blocker is disclosed. Diabetic complications arise from diabetes and have few or no existing treatment options. The present invention describes the use of a beta-blocker in the treatment of a diabetic. The present invention also describes the inhibition of aldose reductase, one of the chief causative factors of diabetic complications. Also provided are methods of diabetic wound healing. Compositions for treating diabetic complications, such as diabetic wounds, are disclosed. The present invention includes employing a topical formulation of a beta-blocker, having substantially no antibacterial activity, to improve the process of diabetic wound healing. The present invention also involves increasing the rate of collagen accumulation of the healing epithelialized tissue in the wound of a diabetic individual.

5. 发明授权

EP2114386B9 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DIABETIC COMPLICATIONS 有权
标题翻译：药物组合物，糖尿病并发症的治疗
公开(公告)号：EP2114386B9
公开(公告)日：2013-09-18
申请号：EP08720107.5
申请日：2008-01-24
申请人： Vlife Sciences Technologies Pvt Ltd.
发明人： DESHPANDE, Supreet, K. , KULKARNI, Sudhir, A. , GOLLAPUDY, Reena, R.
IPC分类号： A61K31/00 , A61K31/215 , A61P3/10
CPC分类号： A61K31/00 , A61K31/215

6. 发明授权

EP2114386B1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DIABETIC COMPLICATIONS 有权
标题翻译：药物组合物，糖尿病并发症的治疗
公开(公告)号：EP2114386B1
公开(公告)日：2012-12-26
申请号：EP08720107.5
申请日：2008-01-24
申请人： Vlife Sciences Technologies Pvt Ltd.
发明人： DESHPANDE, Supreet, K. , KULKARNI, Sudhir, A. , GOLLAPUDY, Reena, R.
IPC分类号： A61K31/00 , A61K31/215 , A61P3/10
CPC分类号： A61K31/00 , A61K31/215

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