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1. 发明公开

EP3676282A1 ANTI-CANCER AGENT 有权转让
公开(公告)号：EP3676282A1
公开(公告)日：2020-07-08
申请号：EP18868922.8
申请日：2018-10-17
申请人： University of Wollongong
发明人： DILLON, Carolyn Therese , CARRALL, Judith Anne
IPC分类号： C07K7/06 , C07F9/76 , C07F9/78 , A61K33/36 , A61K47/64 , A61P35/00

2. 发明授权

EP1481265B1 METHOD AND APPARATUS FOR REAL TIME DOSIMETRY 有权
标题翻译：方法和设备进行实时剂量
公开(公告)号：EP1481265B1
公开(公告)日：2014-06-04
申请号：EP03700224.3
申请日：2003-01-24
申请人： UNIVERSITY OF WOLLONGONG
发明人： ROZENFELD, Anatoly , ZAIDER, Marco
IPC分类号： G01T1/29 , A61N5/10
CPC分类号： A61N5/1048 , A61N5/1007 , A61N5/1027 , A61N5/1071 , A61N2005/1072

3. 发明公开

EP2553493A2 HIGH PERFORMANCE COMPUTING FOR THREE DIMENSIONAL PROTON COMPUTER TOMOGRAPHY (HPC-PCT) 有权
标题翻译：高性能计算三维质子计算机层析成像（HPC-PCT）
公开(公告)号：EP2553493A2
公开(公告)日：2013-02-06
申请号：EP11798535.8
申请日：2011-04-04
申请人： Northern Illinois University , Fermi Research Alliance, LLC , University of Wollongong
发明人： KARONIS, Nicholas , COUTRAKON, George , DUFFIN, Kirk , ERDELYI, Bela , NAGLICH, Kevin , PENFOLD, Scott , RUBINOV, Paul , RYKALIN, Victor , ZUTSHI, Vishnu
IPC分类号： G01T1/161
CPC分类号： G01T1/20 , A61B6/4258 , G01T1/201 , G01T1/208 , G01T1/248 , G01T1/249 , G01T1/2985
摘要： A proton computed tomography (pCT) detector system, including two tracking detectors in sequence on a first side of an object to be imaged, two tracking detectors in sequence on an opposite side of the object to be imaged, a calorimeter, and a computer cluster, wherein the tracking detectors include plastic scintillation fibers. All fibers in the detector system are read out by Silicon Photomultipliers (SiPM). A method of imaging an object by emitting protons from a source through two tracking detectors, through and around the object, and through two opposite tracking detectors, detecting energy of the protons with a calorimeter, and imaging the object.
摘要翻译：一种质子计算机断层扫描（pCT）检测器系统，其包括在要成像的物体的第一侧上依次布置的两个跟踪检测器，在待成像的物体的相对侧上依次布置的两个跟踪检测器，量热计和计算机集群其中跟踪检测器包括塑料闪烁纤维。检测器系统中的所有光纤都由硅光电倍增管（SiPM）读出。一种通过从源通过两个跟踪检测器发射质子穿过物体并围绕物体并通过两个相反的跟踪检测器来成像物体的方法，用热量计检测质子的能量并对物体成像。

4. 发明授权

EP2131849B1 COMPOSITIONS AND METHODS FOR DELIVERY OF ANTI-CANCER AGENTS 有权转让
标题翻译：成分和方法分配的资金对抗癌症的
公开(公告)号：EP2131849B1
公开(公告)日：2011-10-26
申请号：EP08714327.7
申请日：2008-02-29
申请人： The University Of Wollongong
发明人： BREMNER, John, Barnard , CLINGAN, Philip , LOCKE, Julie, Myree
IPC分类号： A61K31/724 , A61K31/505 , A61K31/519 , A61P35/00
CPC分类号： A61K31/505 , A61K9/0019 , A61K31/519 , A61K31/724 , A61K47/40
摘要： The present invention relates to compositions comprising 5-fluorouracil, or a pharmaceutically acceptable salt or analogue thereof, folinic acid, or a pharmaceutically acceptable salt thereof and a cyclodextrin, or a pharmaceutically acceptable salt or derivative thereof. The invention also relates to methods for the treatment of cancer using such compositions.

5. 发明公开

EP2343285A2 Peptoid compounds 有权
标题翻译： Als Antibiotika geeignete peptoide Verbindungen
公开(公告)号：EP2343285A2
公开(公告)日：2011-07-13
申请号：EP11158209.4
申请日：2002-06-28
申请人： UNIVERSITY OF WOLLONGONG
发明人： Bremner, John , Pyne, Stephen , Keller, Paul , Coghlan, Dan , Garas, Adel , Witchard, Helen , Boyle, Tim , Coates, Jonathan
IPC分类号： C07D245/04 , C07D255/04 , C07D273/08 , C07D273/02 , C07D487/02 , C07D209/18 , C07D209/88 , C07C233/31 , C07K5/06 , C07K5/08 , C07K5/10 , A61K38/12 , A61K38/06 , A61P31/04
CPC分类号： C07C229/36 , A61K38/00 , C07C233/47 , C07C237/22 , C07C251/24 , C07C279/14 , C07D209/86 , C07D245/04 , C07D255/04 , C07D273/02 , C07D487/04 , C07K5/06086 , C07K5/06095 , C07K5/0812 , C07K5/1016
摘要： A compound of the formula (I): wherein

A is an aromatic or heteroaromatic ring system or partially or fully reduced derivatives thereof;
Q is hydrogen, C 1 -C 12 straight chain, branched or cyclic alkyl substituted with one or more hydroxy groups, or a mono- or di-saccharide moiety;
Z is -CR 10 R 11 -, -NR 12 -, -C(O)O-, -C(O)NR 12 - or -O-, where R 10 and R 11 are independently selected from hydrogen, hydroxy, C 1 -C 6 alkyl, C 6 -C 10 aryl, C 1 -C 6 alkoxy and -N(R 13 ) 2 and where each R 13 is independently selected from hydrogen and C 1 -C 6 alkyl, and where R 12 is selected from hydrogen and C 1 -C 6 alkyl; R 1 is selected from hydrogen, hydroxy, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, -NR(R 13 ) 2 and -N(R 12 )-COR 14 ; where R 12 and R 13 are as defined above, and where R 14 is selected from hydrogen, hydroxy, C 1 -C 6 alkyl, C 1 -C 6 alkoxy and -NR 12 ;
R 2 is selected from hydrogen, hydroxy, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, -N(R 13 ) 2 and -N(R 12 )-COCHR 2a R 2b ; where R 2a and R 2b are selected from hydrogen, hydroxy, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, -N(R 13 ) 2 and -N(R 12 )-COR 14 ; where R 12 , R 13 and R 14 are as defined above;
R 3 , R 4 and R 5 are independently selected from hydrogen, C 1 -C 6 alkyl and α side chains of α-amino acids or their enantiomers or their derivatives;
R 6 is -CO 2 R 15 , -CONHR 16 , -CONHOR 16 , -CONHNHR 16 , -SO 2 N(R 16 ) 2 , -SO 2 R 17 or -P(O)(OR 18 )(OR 18 ) where each R 15 , R 16 , R 17 and R 18 is independently selected from hydrogen, C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, C 6 -C 10 aryl and C 7 -C 10 arylalkyl;
B is an α-amino acid residue, a β-amino acid residue or an α,α-disubstituted amino acid residue, such residue forming amide linkages with the adjacent molecules;
W is -O- or CR 10 R 11 where R 10 and R 11 are as defined above;
Y is an optionally substituted amino group, a moiety containing an optionally substituted amino group or a salt thereof:
------ is a single or double bond;
R 7 and R 8a are hydrogen or are absent if ------ is a double bond; and
R 8b and R 9 are hydrogen, and X is selected from (CR 10 R 11 ) u , -(CR 10 R 11 ) u -CH=CH-, -NR 12 (CR 10 R 11 ) u -, -(CR 10 R 11 ) u NR 12 -, -O(CR 10 R 11 ) u -, -(CR 10 R 11 ) u O- or -O(CR 10 R 11 )CH=CH- where R 10 , R 11 and R 12 are as defined above; or
R 8b and R 9 together form a covalent bond between X and the carbon to which R 8b is attached, and X is selected from (CR 10 R 11 ) x , -NR 12 (CR 10 R 11 ) x -, -(CR 10 R 11 ) x NR 12 -, -O(CR 10 R 11 ) x - or -(CR 10 R 11 ) x O-, where R 10 , R 11 and R 12 are as defined above;
n, m, r and t are independently selected from 0 or 1;
s is an integer selected from 0 to 3;
p is an integer selected from 0 to 6, provided that when W is -O-, p is at least 1; and u, x and q are independently selected from 0 to 4;
and salts and pharmaceutically acceptable derivatives thereof.
The compound of formula (I) are useful in the treatment of bacterial infections.
摘要翻译：式（I）的化合物：其中A是芳族或杂芳族环系统或其部分或完全还原的衍生物; Q是氢，C 1 -C 12直链，被一个或多个羟基取代的支链或环状烷基，或单糖或二糖部分; Z是-CR 10 R 11 - ， - NR 12 - ， - C（O）O-，-C（O）NR 12 - 或-O-，其中R 10和R 11独立地选自氢，羟基，C 1 -C 6烷基，C 6 -C 10芳基，C 1 -C 6烷氧基和-N（R 13）2，并且其中每个R 13独立地选自氢和C 1 -C 6烷基，并且其中R 12是选自氢和C 1 -C 6烷基; R 1选自氢，羟基，C 1 -C 6烷基，C 1 -C 6烷氧基，-NR（R 13）2和-N（R 12）-COR 14; 其中R 12和R 13如上定义，并且其中R 14选自氢，羟基，C 1 -C 6烷基，C 1 -C 6烷氧基和-NR 12; R 2选自氢，羟基，C 1 -C 6烷基，C 1 -C 6烷氧基，-N（R 13）2和-N（R 12）-COCHR 2a R 2b; 其中R 2a和R 2b选自氢，羟基，C 1 -C 6烷基，C 1 -C 6烷氧基，-N（R 13）2和-N（R 12）-COR 14; 其中R 12，R 13和R 14如上所定义; R 3，R 4和R 5独立地选自氢，C 1 -C 6烷基和± - 氨基酸的±侧链或其对映异构体或其衍生物; R 6是-CO 2 R 15，-CONHR 16，-CONHOR 16，-CONHNHR 16，-SO 2 N（R 16）2，-SO 2 R 17或-P（O）（OR 18）（OR 18）其中每个R 15，R 16，R 17和R 18独立地选自氢，C 1 -C 6烷基，C 3 -C 7环烷基，C 6 -C 10芳基和C 7 -C 10芳基烷基; B是一个± - 氨基酸残基，一个2-氨基酸残基或一个±， - 二取代的氨基酸残基，这样的残基与相邻分子形成酰胺键; W是-O-或CR 10 R 11，其中R 10和R 11如上所定义; Y是任选取代的氨基，含有任选取代的氨基或其盐的部分： - 是单键或双键; 如果 - 是双键，R 7和R 8a是氢或不存在; 并且R 8b和R 9是氢，X选自（CR 10 R 11）u， - （CR 10 R 11）u -CH = CH-，-NR 12（CR 10 R 11）u - ， - （ CR 10 R 11）u NR 12 - ， - O（CR 10 R 11）u - ， - （CR 10 R 11）u O-或-O（CR 10 R 11）CH = CH-，其中R 10，R 11 和R 12如上所定义; 或R 8b和R 9一起在X与连接有R 8b的碳之间形成共价键，X选自（CR 10 R 11）x，-NR 12（CR 10 R 11）x - ， - （ CR 10 R 11）x NR 12 - ， - O（CR 10 R 11）x - 或 - （CR 10 R 11）x O-，其中R 10，R 11和R 12如上所定义; n，m，r和t独立地选自0或1; s为0〜3的整数; p是选自0至6的整数，条件是当W为-O-，p为至少1; 并且u，x和q独立地选自0至4; 及其盐和药学上可接受的衍生物。式（I）化合物可用于治疗细菌感染。

6. 发明公开

EP2199300A3 Peptidic compounds 审中-公开
标题翻译：肽化合物
公开(公告)号：EP2199300A3
公开(公告)日：2010-09-15
申请号：EP10003545.0
申请日：2005-09-21
申请人： The University Of Wollongong
发明人： Boyle, Timothy, Patrick , Bremner, John, Barnard , Brkic, Zinka , Coates, Jonathan, Alan, Victor , Dalton, Neal, Kevin , Deadman, John , Keller, Paul, Anthony , Morgan, Jody , Pyne, Stephen, Geoffrey , Rhodes, David, Ian , Robertson, Mark, James
IPC分类号： C07K5/06 , C07C277/00 , A61P31/04
CPC分类号： C07K5/0812 , C07C235/20 , C07C237/22 , C07C279/14 , C07D213/46 , C07D263/32 , C07D263/46 , C07D273/02 , C07D273/08 , C07D311/70 , C07K5/06086 , C07K5/06191 , C07K5/0808 , C07K5/0815 , C07K5/0827 , C07K5/1016 , C07K5/1027
摘要： The present invention provides a compound of formula (I), (II), (III) and (IV) as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention.

7. 发明公开

EP1641976A1 ELECTROCONDUCTIVE TEXTILES 审中-公开
标题翻译：导电纺织品
公开(公告)号：EP1641976A1
公开(公告)日：2006-04-05
申请号：EP04737481.4
申请日：2004-06-28
申请人： COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION , UNIVERSITY OF WOLLONGONG
发明人： HOLCOMBE, Barry, Victor, , WATERS, Peter, John, , LOONEY, Mark, Graham, , KING, David, George, , WALLACE, Gordon, George, , INNIS, Peter, Charles, , ASHRAF, Syed, Aziz,
IPC分类号： D06M15/356
CPC分类号： D06M15/61 , D06M15/356 , D06M2200/00 , D06N3/12 , D06N3/183 , Y10T442/2459
摘要： An electroconductive textile comprising: a non-conductive textile such as a wool-containing fabric, a macromolecular template which is bonded to or entrapped in the non-conductive textile such as poly 2-methoxyaniline-5-sulfonic acid (PMAS), and a conductive polymer which is ordered by and bonded to the macromolecular template such as polyaniline; in which the macromolecular template binds the conductive polymer to the non-conductive textile.

8. 发明公开

EP1594876A1 CONDUCTING POLYMERS WITH PORPHYRIN CROSS-LINKERS 审中-公开
标题翻译：开展与PORPHYRINQUERVERNETZERN聚合物
公开(公告)号：EP1594876A1
公开(公告)日：2005-11-16
申请号：EP04706576.8
申请日：2004-01-30
申请人： UNIVERSITY OF WOLLONGONG , MASSEY UNIVERSITY
发明人： ON TOO, Chee , CHEN, Jun , WALLACE, Gordon , OFFICER, David, L. , CAMPBELL, Wayne, Mason , BURRELL, Anthony, Keiran , COLLIS, Gavin, Errol
IPC分类号： C07D487/22 , C08G61/12 , H01L31/18
CPC分类号： C08G73/0611 , C07D409/14 , C08G61/02 , C08G61/124 , C08G73/0266 , H01G9/2059 , H01L51/0006 , H01L51/0035 , H01L51/0036 , H01L51/004 , H01L51/0077 , H01L51/4206 , Y02E10/542 , Y02E10/549
摘要： The invention relates to a cross-linking monomer having the structure Q-(L)n-P-(L')m;-Q', where Q and Q' are polymerisable units, L and L' are linkers providing direct or indirect electronic communication between Q and P and between P and Q', and P is an electrofunctional unit, and also to polymers prepared from such monomers. Q for example may be a heteroaromatic ring such as thiophene, furan and pyrrole. The electrofunctional group may be, for example, porphyrin, substituted porphyrin, phthalocyanine or substituted phthalocyanine. The invention also relates to an electrofunctional material including a base material and a cross-linked polymer such as described.

9. 发明公开

EP1509357A1 CONTROL METHOD AND SYSTEM FOR METAL ARC WELDING 有权
标题翻译：控制系统和电弧焊的程序
公开(公告)号：EP1509357A1
公开(公告)日：2005-03-02
申请号：EP03722091.0
申请日：2003-05-30
申请人： UNIVERSITY OF WOLLONGONG
发明人： NORRISH, John , COOK, Christopher, David , CUIURI, Dominic , DI PIETRO, Paul , DEAN, Gary
IPC分类号： B23K9/095 , B23K9/173
CPC分类号： B23K9/124 , B23K9/09 , B23K9/091 , B23K9/095
摘要： A method of controlling an arc welding system during a welding process is disclosed. The welding process has a plurality of welding cycles in which a consumable electrode (14) is advanced towards a workpiece (16). The method includes dynamically regulating a rate of advancement and instantaneous melt rate of the electrode during each welding cycle in response to predetermined events occurring during the welding process. The melt rate may be coordinated with the rate of advancement of the electrode to provide a wide range of stable deposition rates with a shielding gas such as CO2. An arc welding system for carrying out the method is also disclosed.

10. 发明授权

EP2004840B1 SENSOR COMPRISING CONDUCTING POLYMER MATERIALS 有权
标题翻译：与官员高分子材料SENSOR
公开(公告)号：EP2004840B1
公开(公告)日：2014-10-29
申请号：EP07736103.8
申请日：2007-04-13
申请人： Dublin City University , UNIVERSITY OF WOLLONGONG
发明人： MORRIN, Aoife , SMYTH, Malcolm , KILLARD, Anthony, J. , NGAMNA, Orawan , WALLACE, Gordon, George , MOULTON, Simon, Edward , CROWLEY, Karl
IPC分类号： G01N33/543 , C12Q1/00 , G01N33/84
CPC分类号： G01N33/5438 , C12Q1/001 , C12Q1/006 , G01N33/84 , Y10T428/24893

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