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2. 发明公开

EP3041824A1 PROCESS FOR PREPARING CYCLIC CHIRAL AMINES AND ALCOHOLS BY INTRAMOLECULAR CATALYTIC ARYLATION OF BORONIC ACID OR ESTER ALDEHYDES AND IMINE SUBSTRATES 审中-公开
标题翻译：用于生产循环手性胺和醇BY硼酸或-ESTERALDEHYDEN与亚胺底物分子内催化芳基化
公开(公告)号：EP3041824A1
公开(公告)日：2016-07-13
申请号：EP14772447.0
申请日：2014-09-01
申请人： Universidade de Évora
发明人： BURKE, Anthony , SILVA MARQUES, Carolina , SILVA PEIXOTO, Daniela Alexandra , MATOS VIANA, Hugo Ricardo , BRITO GOTH, Albertino João
IPC分类号： C07D215/04 , C07D311/22 , C07D313/08 , C07D217/24 , C07D225/06
CPC分类号： C07D311/22 , C07D215/04 , C07D217/24 , C07D225/06 , C07D313/08
摘要： The present application provides a catalytic process which involves the cyclization of a novel catalytic intramolecular arylation process that involves boronic acid or ester aldehydes or imines substrates, of formula (I) and (II), to afford cyclic chiral alcohols or amines, of formula (VI) and (VII), respectably. The present application also describes the preparation of the substrates of formula (I) and (II) from simple commercial raw materials by efficient processes, some of which are catalytic.
摘要翻译：（本申请提供的催化过程，其中涉及一种新颖的催化的分子内的芳基化processthat的环化涉及到硼酸或酯的醛或式（I的亚胺基板）和（II），得到环状的手性醇或cardamines，式 VI）和（VII），体面。因此，本申请描述了式（I）和（II）由高效的工艺简单的商业原料，其中一些是催化的基底的制备。

3. 发明授权

EP3772277B1 DEVICE AND PROCESS FOR MASSIVE CAPTURE OF OLIVE FLIES - ELECTROCUTOR TRAP 有权
公开(公告)号：EP3772277B1
公开(公告)日：2024-01-17
申请号：EP19190294.9
申请日：2019-08-06
发明人： Rei, Fernando , Gomes, Luis , Andrade, Leonardo , Tlemcani, Mouhaydine , Peça, José , Dias, António
IPC分类号： A01M1/02 , A01M1/22

4. 发明授权

EP3553054B1 FLUORESCENT COUMARIN COMPOUNDS AND METHOD OF SYNTHESIS THEREOF 有权
公开(公告)号：EP3553054B1
公开(公告)日：2023-01-11
申请号：EP18398004.4
申请日：2018-04-13
发明人： Pereira, António Manuel Deométrio Rodrigues Lourenço , Martins, Sérgio Miguel Amaral , Caldeira, Ana Teresa Fialho Caeiro , Candeias, António José Estevão Grande
IPC分类号： C07D311/16 , G01N33/533

5. 发明公开

EP3744246A1 MULTIDIMENSIONAL TOOL FOR ASSESSING THE RISK OF FALLING IN OLDER PEOPLE 有权
公开(公告)号：EP3744246A1
公开(公告)日：2020-12-02
申请号：EP19177227.6
申请日：2019-05-29
申请人： Universidade de Évora
发明人： ROSA PARREIRA MENDES, FELISMINA , LINO NETO PEREIRA, CATARINA , DUARTE DOS SANTOS BRAVO, JORGE , DE CASTRO MARTINS SECCA RUIVO, MARIA INÊS , DA MOTA CERVEIRA NAZULINO GONÇALVES, TIAGO JOSÉ
IPC分类号： A61B5/11 , A61B5/00 , A61B50/13 , A61G12/00
摘要： This application describes a multidimensional tool for evaluating the risk of falling, particularly in older people. The tool hereby described was developed from a trolley-style box, built specifically to comprise different measuring instruments that allow for the application of physical, functional and cognitive tests, and clinical questionnaires duly validated in the international literature, in order to obtain data to assess the risk of falling. The mobility of the tool allows for the easy transportation of all the instruments enabling the tool to be taken directly to the population for assessment. This tool is also associated with a dynamic statistical model for predicting the risk of falling, that allows for the adjustment of the final result of the risk in accordance with the tests performed.

6. 发明公开

EP3310765A1 PROCESS FOR PREPARING 1,4-DIBENZODIAZEPINES VIA BUCHWALD-HARTWIG CHEMISTRY 审中-公开
标题翻译：通过BUCHWALD-HARTWIG化学法制备1,4-二苯并噻吖庚因的方法
公开(公告)号：EP3310765A1
公开(公告)日：2018-04-25
申请号：EP16742398.7
申请日：2016-06-21
申请人： Universidade de Évora
发明人： BURKE, Anthony , SILVA PEIXOTO, Daniela Alexandra
IPC分类号： C07D243/10
CPC分类号： C07D243/10 , B01J31/24
摘要： The present application provides a one-pot catalytic process which involves the formation of 1,4-dibenzodiazepines from o-haloaldimines (either pre-formed or formed in situ) of formula (I) and o-haloanilines of formula (II) via a palladium catalyzed Buchwald-Hartwig reaction and a cyclization sequence, to afford the 1,4-dibenzodiazepine products of formula (III). The present application describes the preparation of the 1,4-dibenzodiazepine products of formula (III) from simple commercial raw materials by efficient processes.

7. 发明公开

EP3055062A1 NOVEL PICOLINAMIDE-CINCHONA ORGANOCATALYSTS AND DERIVATIVES 审中-公开
标题翻译：新型吡啶酰胺金鸡纳有机催化剂及其衍生物的
公开(公告)号：EP3055062A1
公开(公告)日：2016-08-17
申请号：EP14799542.7
申请日：2014-10-07
申请人： Universidade de Évora
发明人： BURKE, Anthony , CAMBEIRO BARRULAS, Pedro Miguel
IPC分类号： B01J31/02
CPC分类号： B01J31/0247 , B01J35/0033 , B01J2231/323 , B01J2231/643 , B01J2531/0269 , C07C209/00 , C07C213/00 , C07D453/04 , C07F7/1892
摘要： The present application describes a novel type of picolinamide-cinchona organocatalyst that allows for the successful transformation of ketimines to chiral amines with very high enantioselectivities and with the highest TOFs reported for any particular organocatalyst to date. These organocatalysts have also been immobilized to a variety of solid supports, including magneto-nanoparticles.

8. 发明公开

EP1928998A2 LIQUID MEDIA FOR CHLAMYDOSPORE PRODUCTION OF THE FUNGUS POCHONIA CHLAMYDOSPORIA 审中-公开
标题翻译：液体培养基对CHLAMYDOSPORE生产蘑菇的影响
公开(公告)号：EP1928998A2
公开(公告)日：2008-06-11
申请号：EP06796017.9
申请日：2006-09-13
申请人： Universidade de Évora
发明人： ANTUNES FRANCO, Carlos, Manuel
IPC分类号： C12N1/14
CPC分类号： C12N1/14 , A01N63/04
摘要： This invention refers to the creation of liquid media to grow the fungus Pochonia chlamydosporia designed to produce conidia of the aleuriospore type, also denominated chlamydospores. These media using easily carried out fermentation processes, achieved productions over 106 chlamydospores/ml. The chlamydospores can then be easily extracted using processes of filtration and separation of solid particles in liquid suspensions. These chlamydospores can be mass collected and utilized to formulate products to use in biological control of Meloidogyne spp. by the nemathophagous fungus P. chlamydosporia, either in small scale trials or at commercial scale.
摘要翻译：本发明涉及液体培养基的生长以培养真菌Pochonia chlamydosporia，所述真菌Pochonia chlamydosporia设计用于产生也指定为衣原体孢子孢子的孢子型孢子。这些培养基使用容易进行的发酵过程，实现了超过106个衣原体/毫升的生产。然后可以使用过滤和在液体悬浮液中分离固体颗粒的方法容易地提取厚膜孢子。这些厚膜孢子可以大量收集并用于配制产品以用于根结线虫属的生物防治。无论是在小规模试验中还是在商业规模上，通过嗜食真菌P. chlamydosporia。

9. 发明公开

EP4353824A1 CONSTRUCT FOR INDUCING SILENCING IN PLANTS AND METHOD FOR PROTECTING THEM AGAINST TOMATO SPOTTED WILT VIRUS 审中-公开
公开(公告)号：EP4353824A1
公开(公告)日：2024-04-17
申请号：EP22201471.4
申请日：2022-10-13
申请人： Universidade de Évora
发明人： REIS VARANDA, CARLA MARISA , DE QUEIROZ MATERATSKI, PATRICK JOSÉ , FERNANDES FÉLIX, MARIA DO ROSÁRIO , MURTEIRA RICO DA COSTA CAMPOS, MARIA DOROTEIA , CARDOSO PATANITA, MARIANA , BARRETO ALBUQUERQUE, ANDRÉ FILIPE , AMARO RIBEIRO, JOANA
IPC分类号： C12N15/82 , C07K14/08
CPC分类号： C12N15/8203 , C12N15/8218 , C12N15/8283 , C12N15/86 , C07K14/005 , C12N2760/1202220130101 , C12N2770/3804320130101 , C12N2770/3803120130101 , C12N2760/1203120130101
摘要： The invention relates to a viral vector for conferring protection of plants against Tomato spotted wilt virus (TSWV), a virus that causes a devastating disease in tomato plants. The virus-based vector was modified to carry part of the TSWV non-structural protein NSm gene, conferring protection against TSWV in plants. The invention also relates to a process for silencing a target gene in a plant comprising the steps of i) obtaining a construct according to the previous claim; ii) introducing the construct inside the plant, preferably by using viral suspensions; inoculating into plants, preferably by spraying plants, even more preferably by spraying plants with a compressor set comprising an airbrush; iii) activating the plant's specific defence mechanism, consequently silencing the target gene. The present invention also discloses a composition for plant disease management and/or plant immunization.

10. 发明授权

EP3912899B1 DEVICE FOR SUPPORTING A SEABED MEASUREMENT UNDERWATER SYSTEM 有权
公开(公告)号：EP3912899B1
公开(公告)日：2023-04-05
申请号：EP20217573.3
申请日：2020-12-29
发明人： RIBEIRO, Carlos , TERRINHA, PEDRO , BRITO, PEDRO , ROSA, MARCOS , GONÇALVES, JOÃO
IPC分类号： B63B49/00 , B63C11/48 , G01S7/521

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