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1. 发明授权

EP0983072B2 USE OF INULIN FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PREVENTION AND TREATMENT OF COLON CANCER 失效
标题翻译：菊粉结肠癌的准备药物预防和治疗DICK使用
公开(公告)号：EP0983072B2
公开(公告)日：2008-07-16
申请号：EP98924315.9
申请日：1998-05-14
申请人： Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.)
发明人： VAN LOO, Jan , FRIPPIAT, Anne
IPC分类号： A61K31/715
CPC分类号： A61K31/733 , A23L29/055 , A23L29/244
摘要： The use is provided of a fructan with an average degree of polymerisation of at least 15 for the manufacture of a composition for the prevention and/or treatment of colon cancer in non-bovine mammals, particularly in human beings. Also provided is a method of prevention and treatment of colon cancer in a non-bovine mammal, particularly in a human being, comprising administering to said mammal a composition comprising an effective dose of a fructan with an average degree of polymerisation of at least 15. The said composition can be a medicament as well as a functional food. In a preferred embodiment the fructan is inulin, more preferably inulin with an average degree of polymerisation of at least 20.

2. 发明授权

EP0983072B1 USE OF FRUCTAN FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PREVENTION AND TREATMENT OF COLON CANCER 失效
标题翻译：菊粉结肠癌的准备药物预防和治疗DICK使用
公开(公告)号：EP0983072B1
公开(公告)日：2004-08-25
申请号：EP98924315.9
申请日：1998-05-14
申请人： Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.)
发明人： VAN LOO, Jan , FRIPPIAT, Anne
IPC分类号： A61K31/715
CPC分类号： A61K31/733 , A23L29/055 , A23L29/244
摘要： The use is provided of a fructan with an average degree of polymerisation of at least 15 for the manufacture of a composition for the prevention and/or treatment of colon cancer in non-bovine mammals, particularly in human beings. Also provided is a method of prevention and treatment of colon cancer in a non-bovine mammal, particularly in a human being, comprising administering to said mammal a composition comprising an effective dose of a fructan with an average degree of polymerisation of at least 15. The said composition can be a medicament as well as a functional food. In a preferred embodiment the fructan is inulin, more preferably inulin with an average degree of polymerisation of at least 20.

3. 发明公开

EP0930317A1 Process for the manufacture of chicory inulin, hydrolysates and derivatives of inulin, and improved chicory inulin products, hydrolysates and derivatives 失效
标题翻译：一种用于制备菊糖从菊苣，Inulinhydrolysate及衍生物，制品，水解物和菊苣菊糖的衍生物的方法
公开(公告)号：EP0930317A1
公开(公告)日：1999-07-21
申请号：EP98870012.6
申请日：1998-01-21
申请人： Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.)
发明人： Smits, Georges , De Leenheer, Leen
IPC分类号： C08B37/18 , A01G1/00
CPC分类号： C08B37/0054
摘要： The invention provides an improved process for the manufacture of chicory inulin, hydrolysates and derivatives of inulin by conventional manufacturing techniques from roots of chicory grown in appropriate regions and which have been grown and processed under proper climatological temperature conditions. Selection of said proper conditions enables to provide a growing and/or processing period for the chicory roots which may partly or wholly extend beyond the conventional periods.
The invention relates also to improved grades of chicory inulin, of hydrolysates of chicory inulin, such as e.g. a polydisperse oligofructose composition and a fructose composition, as well as to the use of these products in the manufacture of food, feed, drinks, prophylactic and therapeutical compositions , chemical derivatives and non-food compositions.
Improved standard grade chicory inulin according to the invention presents a degree of polymerisation ( DP ¯ ) which is at least 20 % higher than the one of conventional standard grade chicory inulin.
摘要翻译：对本发明的改进的方法提供用于制造菊苣菊糖，水解菊糖和衍生物的通过从生长在适当区域和已生长和合适的气象温度条件下加工的菊苣根的常规制造技术。的适当条件的选择说能够提供对菊苣根这可能部分或全部超出常规周期的生长和/或处理期间。因此，本发明涉及改进的菊苣菊糖的等级，菊苣菊糖的水解物，：如大肠杆菌G. 多分散低聚果糖组合物和果糖组分，以及在食品，饲料，饮料，预防和治疗的组合物，化学衍生物和非食品组合物的制造中使用的合成产品。改良的标准级菊苣菊糖gemäß到本发明提出的聚合度（DP）的所有其比以往的标准级菊苣菊糖的一个高至少20％。

4. 发明授权

EP0769026B2 FRACTIONATED POLYDISPERSE COMPOSITIONS 有权转让
标题翻译：分次多分散成分
公开(公告)号：EP0769026B2
公开(公告)日：2005-02-16
申请号：EP95926341.9
申请日：1995-07-07
申请人： Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.)
发明人： SMITS, Georges , DAENEKINDT, Luc , BOOTEN, Karl
IPC分类号： C08B37/18 , A61K31/75 , A23L1/0528
CPC分类号： A23G1/56 , A23C9/137 , A23C9/1544 , A23C13/12 , A23C19/0285 , A23C19/0765 , A23C19/082 , A23D7/015 , A23G3/346 , A23G2200/06 , A23L9/12 , A23L13/65 , A23L13/67 , A23L23/00 , A23L27/60 , A23L29/244 , A23P30/40 , A61K8/73 , A61Q19/00 , C08B37/0054
摘要： The present invention concerns a new fractionated polydisperse carbohydrate composition having the following definition: an av. DP which is significantly higher than the av. DP of a native polydisperse carbohydrate composition, significantly free of low molecular monomers, dimers, and oligomers, significantly free of impurities chosen among the group consisting of colourings, salts, proteins and organic acids, significantly free of technological aids such as solubility affecting products. The present invention concerns also the preparation process of the composition according to the invention.

5. 发明授权

EP1079840B1 SYNERGISTIC COMPOSITION OF INULIN AND AN ANTI-CANCER DRUG FOR USE IN THE TREATMENT OF CANCER 有权
标题翻译：协同组合物用于治疗癌症的WHICH菊粉和抗癌存在
公开(公告)号：EP1079840B1
公开(公告)日：2002-10-02
申请号：EP99924999.8
申请日：1999-05-18
申请人： Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.)
发明人： TAPER, Henryk , FRIPPIAT, Anne , VAN LOO, Jan , ROBERFROID, Marcel
IPC分类号： A61K31/70 , A61K31/505 , A61K31/52 , A61K31/17 , A61K31/715
CPC分类号： A61K31/7004 , A61K31/715 , A61K45/06 , A61K31/70 , A61K31/52 , A61K31/505 , A61K31/17 , A61K2300/00
摘要： The present invention provides (i) a novel pharmaceutical composition comprising a synergistic combination of a non-digestible fructan-type carbohydrate, i.e. an inulin (including inulin, oligofructose and mixtures thereof) and an anti-metabolic anti-cancer drug, (ii) said composition for use in the treatment of cancer in humans and in non-ruminating mammals, (iii) the use of said combination for the manufacture of a medicament for the treatment of cancer in humans and in non-ruminating mammals, and (iv) the use of said composition in a method for treatment of cancer in humans and in non-ruminating mammals.

6. 发明授权

EP0963379B1 LOW DENSITY FRUCTAN AND COMPOSITION CONTAINING IT 有权
标题翻译：具有低密度和含ZUZAMMENSETZUNG果聚糖
公开(公告)号：EP0963379B1
公开(公告)日：2001-06-13
申请号：EP98901264.6
申请日：1998-01-30
申请人： Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.)
发明人： DE SOETE, Johan , BOOTEN, Karl , DAENEKINDT, Luc
IPC分类号： C08B37/18 , A23L1/00 , A23L1/308 , A23L1/0528 , C13F3/00
CPC分类号： C08L5/00 , A23L29/244 , A23P10/30
摘要： The present invention is related to a low density fructan composition having a density equal or less than 0.35 g/ml, to a composition which comprises intimately associated with the fructan one or more elements chosen among the group consisting of maltodextrins, polydextrose, sucrose, polyols and high intensity sweeteners, and to said composition which exhibits instant dispersion properties in an aqueous medium.

7. 发明公开

EP1079840A1 SYNERGISTIC COMPOSITION OF INULIN AND AN ANTI-CANCER DRUG FOR USE IN THE TREATMENT OF CANCER 有权
标题翻译：协同组合物用于治疗癌症的WHICH菊粉和抗癌存在
公开(公告)号：EP1079840A1
公开(公告)日：2001-03-07
申请号：EP99924999.8
申请日：1999-05-18
申请人： Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.)
发明人： TAPER, Henryk , FRIPPIAT, Anne , VAN LOO, Jan , ROBERFROID, Marcel
IPC分类号： A61K31/70 , A61K31/505 , A61K31/52 , A61K31/17 , A61K31/715
CPC分类号： A61K31/7004 , A61K31/715 , A61K45/06 , A61K31/70 , A61K31/52 , A61K31/505 , A61K31/17 , A61K2300/00
摘要： The present invention provides (i) a novel pharmaceutical composition comprising a synergistic combination of a non-digestible fructan-type carbohydrate, i.e. an inulin (including inulin, oligofructose and mixtures thereof) and an anti-metabolic anti-cancer drug, (ii) said composition for use in the treatment of cancer in humans and in non-ruminating mammals, (iii) the use of said combination for the manufacture of a medicament for the treatment of cancer in humans and in non-ruminating mammals, and (iv) the use of said composition in a method for treatment of cancer in humans and in non-ruminating mammals.

8. 发明公开

EP0964054A1 Surface-active alkylurethanes of fructans 失效
标题翻译： Grenzflächenaktive - alkylurethanen von Fructan
公开(公告)号：EP0964054A1
公开(公告)日：1999-12-15
申请号：EP98870135.5
申请日：1998-06-11
申请人： Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.)
发明人： Stevens, Christian Victor , Booten, Karl , Laquiere, Isabelle M-A. , Daenekindt, Lucien
IPC分类号： C11D1/66 , C08B37/18 , C07H3/00
CPC分类号： C08B37/0051 , C07H3/00 , C11D1/10 , C11D1/50
摘要： The invention concerns the use as surface-active agent of a fructan N-alkylurethane (I) which is composed of saccharide units of general formula (II)

A (O - CO - NH - R) s (II)

wherein

A represents a fructosyl unit (F) or a terminal glucosyl unit (G) of said fructan, being a levan or an inulin, with a degree of polymerisation (DP) of minimum 3,
(O - CO - NH - R) represents an N-alkylaminocarbonyloxy group replacing a hydroxyl group of the saccharide unit A, wherein R represents a linear or branched, saturated or unsaturated alkyl group containing from 3 to 22 carbon atoms and any mixture thereof, and s represents the number of N-alkylaminocarbonyloxy groups per saccharide unit which is expressed as degree of substitution (DS), and said DS has a value ranging from 0.10 to 2.0 . The invention further relates to novel fructan N-alkylurethanes (I), in particular inulin N-alkylurethanes (I), and a method for their manufacture. The fructan N-alkylurethanes (I) have good to excellent surface-active properties in combination with good biodegradability and are suitable as surfactants for use in household and industrial applications, e.g. as detergents, emulsifiers, emulsion stabilisers, foaming agents, foam stabilisers and wetting agents.
摘要翻译：本发明涉及由通式（II）A（O-CO-NH-R）s的糖类单元构成的果聚糖N-烷基氨基甲酸酯（I）的表面活性剂的用途，其中A表示果糖基单元（F ）或聚合度（DP）至少为3的所述果聚糖的末端葡糖基单元（G），其为聚乙烯或菊粉，（O-CO-NH-R）表示取代羟基的N-烷基氨基羰基氧基一组糖单元A，其中R表示含有3至22个碳原子的直链或支链，饱和或不饱和的烷基及其任何混合物，s表示每个糖单元的N-烷基氨基羰基氧基的数目，其表示为度的替代（DS），并且所述DS具有0.10至2.0的值。本发明还涉及新型果聚糖N-烷基氨基甲酸酯（I），特别是菊糖N-烷基氨基甲酸酯（I）及其制备方法。果聚糖N-烷基氨基甲酸酯（I）具有良好至优异的表面活性特性以及良好的生物降解性，并且适合用作家用和工业应用中的表面活性剂，例如。作为洗涤剂，乳化剂，乳液稳定剂，发泡剂，泡沫稳定剂和润湿剂。

9. 发明公开

EP0867470A1 Inulin based hydrocolloid compositions 失效
标题翻译： Zusammensetzungen von Inulin und Hydrokolloiden
公开(公告)号：EP0867470A1
公开(公告)日：1998-09-30
申请号：EP97870039.1
申请日：1997-03-24
申请人： Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.)
发明人： Frippiat, Anne
IPC分类号： C08L5/00 , A23L1/052
CPC分类号： C08L3/02 , A23L29/212 , A23L29/231 , A23L29/238 , A23L29/244 , A23L29/256 , A23L29/262 , A23L29/27 , A23L29/272 , A23L29/284 , A23L29/35 , A23L35/20 , C08L5/00 , C08L2666/02
摘要： The present invention concerns a synergistic composition of hydrocolloids comprising a combination of inulin and another hydrocolloid which is a gelling agent. Preferably the concentration ratio of the components is within the range at which the ratio of the gel strengths of the individual components varies from 0.05 to 20. The use of said composition to obtain a predetermined gel strength in a food product or in an ingredient thereof is also provided.
摘要翻译：本发明涉及包含菊糖和作为胶凝剂的另一种水解胶体的组合的水胶体的协同组合物。优选地，组分的浓度比在各个组分的凝胶强度的比率在0.05至20之间变化的范围内。所述组合物在食品或其成分中获得预定凝胶强度的用途是也提供。

10. 发明授权

EP0867470B1 Inulin based hydrocolloid compositions 失效
标题翻译：菊糖和胶体的组成
公开(公告)号：EP0867470B1
公开(公告)日：2003-05-28
申请号：EP97870039.1
申请日：1997-03-24
申请人： Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.)
发明人： Frippiat, Anne
IPC分类号： C08L5/00 , A23L1/052
CPC分类号： C08L3/02 , A23L29/212 , A23L29/231 , A23L29/238 , A23L29/244 , A23L29/256 , A23L29/262 , A23L29/27 , A23L29/272 , A23L29/284 , A23L29/35 , A23L35/20 , C08L5/00 , C08L2666/02

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