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1. 发明公开

EP1039953A1 DUAL CATHETER RADIATION DELIVERY SYSTEM 审中-公开
标题翻译：双导管放射传送系统
公开(公告)号：EP1039953A1
公开(公告)日：2000-10-04
申请号：EP98963167.6
申请日：1998-12-14
申请人： Radiance Medical Systems, Inc.
发明人： TRAUTHEN, Brett , MCCORMICK, Paul , BUCHBINDER, Maurice , HENSON, Michael
IPC分类号： A61N5/00
CPC分类号： A61N5/1002 , A61N2005/1004
摘要： Disclosed is a dual catheter radiation delivery system, for delivering a dose of radiation to a treatment site, typically in a body lumen. The system comprises an outer sheath catheter, having an inflatable balloon thereon. The system further comprises an inner radiation delivery catheter (30), having a radially expandable structure such as a balloon (48) with a radiation source thereon. The sheath catheter is positioned such that the sheath balloon is at the treatment site, and the radiation delivery catheter is transluminally advanced through the sheath catheter such that the radiation source is positioned within the sheath balloon. The radiation delivery balloon is inflated within the sheath balloon to position the radioactive source near the vessel wall. The source may comprise a thin film carried by the radiation delivery balloon, having a radioactive isotope implanted therein or chemically bonded thereto. Alternatively, the radioactive isotope may be implanted within or adhered to the radiation delivery balloon.
摘要翻译：公开了一种双导管放射递送系统，用于将一定剂量的辐射递送至典型地在体腔中的治疗部位。该系统包括外护套导管，其上具有可膨胀的气囊。该系统还包括内辐射输送导管（30），该内辐射输送导管具有其上具有辐射源的诸如气囊（48）的径向可扩展结构。护套导管定位成使得护套气囊处于治疗部位，并且辐射输送导管通过护套导管透射地前进，使得辐射源定位在护套气囊内。辐射输送气囊在护套气囊内膨胀以将放射源定位在血管壁附近。源可以包括由辐射递送球囊携带的薄膜，其具有植入其中或与之化学结合的放射性同位素。或者，可将放射性同位素植入或附着于放射递送球囊。

2. 发明公开

EP1028782A1 RADIATION DELIVERY CATHETER 审中-公开
标题翻译：导管放射治疗
公开(公告)号：EP1028782A1
公开(公告)日：2000-08-23
申请号：EP98957550.1
申请日：1998-11-04
申请人： Radiance Medical Systems Inc.
发明人： VON HOFFMANN, Gerard
IPC分类号： A61N5/00
CPC分类号： A61N5/1002 , A61N2005/1004
摘要： Disclosed is a delivery catheter (10) adapted for delivery of a dose of radiation to a vessel wall (12). A radiation source (32) is enlarged from a first, reduced cross-sectional profile to a second enlarged cross-sectional profile by unwinding around a central core (22). Following delivery of a radiation dose to the vessel wall (12), the source (32) is reduced in profile by wrapping around the core (22), and removed from the treatment site.

3. 发明公开

EP1056515A1 RADIOACTIVE STENT 审中-公开
标题翻译：放射性支架术
公开(公告)号：EP1056515A1
公开(公告)日：2000-12-06
申请号：EP99909517.7
申请日：1999-02-19
申请人： Radiance Medical Systems Inc.
发明人： TRAUTHEN, Brett, A. , TAM, Lisa , Fazio, Robert
IPC分类号： A61N5/00
CPC分类号： G21G4/06 , A61F2/82 , A61K9/1641 , A61K51/1279 , A61K51/1282 , A61M2025/1075 , A61N5/1002 , A61N2005/1004 , A61N2005/1005 , G03C5/02
摘要： This invention is a radiation delivery source (1) which may be used to deliver a radioactive dose to a site in a body lumen. The source comprises a substrate (10) in the form of a stent (unnumbered), to which is attached a layer (12) of relatively insoluble metal salt which includes at least one radioisotope. Optionally, the source (1) may further include a coating (14) which seals the source.

4. 发明公开

EP1056503A1 THIN FILM RADIATION SOURCE 审中-公开
标题翻译：薄膜辐射源
公开(公告)号：EP1056503A1
公开(公告)日：2000-12-06
申请号：EP99907141.8
申请日：1999-02-19
申请人： Radiance Medical Systems, Inc.
发明人： TRAUTHEN, Brett, A. , TAM, Lisa , FAZIO, Robert
IPC分类号： A61M29/02 , A61M36/12 , A61N5/10
CPC分类号： G21G4/06 , A61F2/82 , A61K9/1641 , A61K51/1279 , A61K51/1282 , A61M2025/1075 , A61N5/1002 , A61N2005/1004 , A61N2005/1005 , G03C5/02
摘要： This invention is a thin film radiation source (10) which may be used to deliver a radioactive dose to a site in a body lumen. The source (10) comprises a thin flexible substrate (12), and a layer of radioisotope (16) attached thereto. The source (10) may further include a tie layer (14) disposed between the substrate (12), and the radioisotope layer (16). The source (10) may be wrapped around a balloon (22).

5. 发明公开

EP1011808A1 RADIATION DELIVERY BALLOON 失效
标题翻译：气球放射治疗
公开(公告)号：EP1011808A1
公开(公告)日：2000-06-28
申请号：EP98904770.9
申请日：1998-01-30
申请人： Radiance Medical Systems Inc.
发明人： CROCKER, Michael , KICK, George, F. , SIMINUK, Mark
IPC分类号： A61N5/00
CPC分类号： A61N5/1002 , A61M25/10 , A61M25/1002 , A61M2025/1075 , A61N2005/1004 , A61N2005/1005
摘要： This invention is a balloon catheter (10) having an inflatable balloon (18) having a radiation carrier (34). The radiation carrier can comprise one or more layers of metal foil, such as gold. Further, the radiation carrier can be a dopant in the balloon material.

6. 发明公开

EP1006941A1 MICROPOROUS TUBULAR PROSTHESIS 失效
标题翻译：微孔管状假
公开(公告)号：EP1006941A1
公开(公告)日：2000-06-14
申请号：EP97948450.8
申请日：1997-11-21
申请人： Radiance Medical Systems Inc.
发明人： MCDONALD, Edward, A. , HENSON, Michael , YOUNG, Joe, W. , ROSENBLUTH, Robert , BRENNEMAN, Rodney
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/0077 , A61F2/856 , A61F2/90 , A61F2/92 , A61F2/954 , A61F2/962 , A61F2002/826 , A61F2002/8483 , A61F2002/9517 , A61F2210/0076 , A61F2210/0095 , A61F2250/0067 , A61N5/1002 , A61N2005/1004
摘要： Disclosed is a tubular microporous prosthesis (10) formed by rolling a flexible sheet (11) around a longitudinal axis. Preferably, the prosthesis (10) is self-expandable under the radially outwardly directed spring bias of the rolled sheet (11). At least a portion of the sheet (11) may be provided with a coating to affect the physical and/or biological properties of the prosthesis.

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