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81. 发明公开

EP2757266A1 Rotary vacuum pump 有权
标题翻译： Rotationsvakuumpumpe
公开(公告)号：EP2757266A1
公开(公告)日：2014-07-23
申请号：EP13152249.2
申请日：2013-01-22
申请人： Agilent Technologies, Inc.
发明人： Emelli, Enrico
IPC分类号： F04D19/04 , F04D29/32
CPC分类号： F04D19/042 , F04D19/046 , F04D29/324
摘要： The present invention refers to a rotary vacuum pump (30) comprising a first set (I) of pumping stages having rotor discs with a first diameter (D1) and a second set (II) of pumping stages having rotor discs (D2) with a second different diameter and further comprising an intermediate pumping stage (1) that is particularly adapted for matching said change in the diameter of the pump rotor discs. According to the invention, said intermediate pumping stage comprises a rotor disc (5) having an outer portion in the radial direction that is axially tapered from its inner diameter to its outer diameter and a corresponding stator stage (3) including a spacer ring (7) that is axially tapered from its periphery toward its center.
摘要翻译：本发明涉及一种旋转式真空泵（30），其包括具有第一直径（D1）的转子盘和具有转子盘（D2）的泵送级的第二组（II）的泵送级的第一组（I）第二不同直径，并且还包括中间泵送阶段（1），其特别适于匹配所述泵转子盘的直径的所述变化。根据本发明，所述中间泵送级包括转子盘（5），其具有在其径向方向上从其内径到其外径的轴向渐缩的外部部分和相应的定子级（3），该定子级包括间隔环（7））从其周边向其中心轴向渐缩。

82. 发明公开

EP2729817A1 METHOD FOR POSITIONING AN ATOMIC FORCE MICROSCOPY TIP IN A CELL 审中-公开
标题翻译：方法核电PEAK观察细胞中的定位
公开(公告)号：EP2729817A1
公开(公告)日：2014-05-14
申请号：EP12808208.8
申请日：2012-07-03
申请人： Agilent Technologies, Inc.
发明人： YAMADA, Nazumi Alice , CURRY, Bo U. , RANKL, Christian
IPC分类号： G01Q60/24 , G01N21/64
CPC分类号： G01Q60/42 , G01Q30/025
摘要： A method for positioning a tip of an atomic force microscope relative to a intracellular target site in a cell is provided. In general terms, the method comprises: a) positioning a fluorescent tip of an atomic force microscope over a cell comprising a fluorescent intracellular target site so that said tip is above target site; b) moving the tip toward said target site while obtaining images of the distal end of said tip and/or the target site using a fluorescence microscope; and c) arresting the movement of the tip when the target site and the distal end of the tip are both in focus in the fluorescence microscope. A microscope system for performing the method is also provided.

83. 发明公开

EP2703810A1 Integrated particle trap for capillary PLOT columns 有权
标题翻译： Integrierte Teilchenfallenfürkapillare PLOT-Säulen
公开(公告)号：EP2703810A1
公开(公告)日：2014-03-05
申请号：EP13176807.9
申请日：2013-07-17
申请人： Agilent Technologies, Inc.
发明人： Peene, Jan Adriaan , Yu, Liying
IPC分类号： G01N30/60 , B01D15/22
CPC分类号： G01N30/6078 , B01D15/206 , B01D15/22 , G01N30/6004 , G01N2030/484 , G01N2030/567 , G01N2030/6008 , G01N2030/6013 , Y10T29/4998
摘要： A porous layer open tubular (PLOT) column (10) includes capillary tubing; one or two particle traps (12a, b) disposed inside one or two end sections of the capillary tubing; and a stationary phase (13) comprising a porous or non-porous material coated inside a main section (11) of the capillary tubing. A method for preparing a porous layer open tubular (PLOT) column includes preparing one or two particle traps inside one or two end sections of a capillary tubing; and preparing a stationary phase comprising a layer of a porous material coated inside a main section of the capillary.
摘要翻译：多孔层开放管（PLOT）柱（10）包括毛细管; 设置在毛细管的一个或两个端部内的一个或两个颗粒捕集器（12a，b）; 和固定相（13），其包括涂覆在所述毛细管的主要部分（11）内的多孔或无孔材料。制备多孔层开放管（PLOT）柱的方法包括在毛细管的一个或两个端部内制备一个或两个颗粒捕集器; 以及制备固定相，其包含涂布在所述毛细管的主要部分内的多孔材料层。

84. 发明公开

EP2677313A1 Compressible fluid pumping system for dynamically compensating compressible fluids over large pressure ranges 审中-公开
标题翻译：对于在大压力范围可压缩流体的动态补偿可压缩流体泵系统
公开(公告)号：EP2677313A1
公开(公告)日：2013-12-25
申请号：EP13168579.4
申请日：2013-05-21
申请人： Agilent Technologies, Inc.
发明人： Berger, Terry A. , Fogelman, Kimber D. , Wikfors, Edwin E.
IPC分类号： G01N30/26 , B01D11/02 , B01D15/40 , G01N30/32
CPC分类号： B01D15/40 , F04B23/10 , G01N30/20 , G01N30/26 , G01N30/32
摘要： An apparatus and a system for converting a standard, high performance liquid chromatography (HPLC) flow path to a flow path suitable for supercritical fluid chromatography (SFC) are described. This reversible technique is applied to a variety of flow configurations including binary, high pressure solvent mixing systems and quaternary, low pressure solvent mixing systems than can be conventionally operated or automated. The technique is generally applied to the fields of supercritical fluid chromatography and high pressure liquid chromatography, but users skilled in the art will find utility for any flow system where pressurization components must be periodically applied to and removed from both ends of a flow stream in an automated manner.
摘要翻译：的装置和用于标准，高效液相色谱法（HPLC）流动路径转换成适合于超临界流体色谱（SFC）的流路的系统进行说明。这种技术是可逆应用于各种流动结构包括二进制，高压溶剂混合系统和季，低压溶剂混合系统相比，可以常规操作的或自动的。该技术适用于超临界流体色谱和高压液相色谱法，但用户领域的技术人员会发现的任何流动系统，其中加压部件必须被周期性地施加到实用程序的字段和除去从在流动流的两端基因反弹自动化的方式。

85. 发明授权

EP2249699B1 DIFFERENTIAL TUNING OF QUADRATURE MODES OF A MAGNETIC RESONANCE COIL 有权
标题翻译： QUADRATURMODI磁线圈的微分调谐
公开(公告)号：EP2249699B1
公开(公告)日：2013-11-20
申请号：EP08780636.0
申请日：2008-05-09
申请人： Agilent Technologies, Inc.
发明人： LOCK, Herman
IPC分类号： A61B5/055 , G01R33/34 , G01V3/00 , G01R33/36
CPC分类号： G01R33/34046 , G01R33/34076 , G01R33/3628 , G01R33/3678 , G01R33/3692
摘要： A coil assembly for transmitting or receiving radio frequency signals includes a coil, a capacitive tuning ring, a first capacitive shield, and a second capacitive shield. The coil includes axial conductors extending between first and second end regions and arranged about a longitudinal axis. The tuning ring is axially movable wherein an amount by which the tuning ring overlaps the plurality of axial conductors is adjustable. The first capacitive shield is axially movable relative to a first group of axial conductors wherein an amount by which the first capacitive shield overlaps the first group is adjustable. The second capacitive shield, offset ninety degrees from the first capacitive shield, is axially movable relative to a second group of axial conductors wherein an amount by which the second capacitive shield overlaps the second group is adjustable. The capacitive shields enable the coil to be quadrature balanced.

86. 发明授权

EP2095145B1 NMR PROBE CONTAINING COILS WITH ELECTRIC FIELD SHIELDS 有权
标题翻译：与REEL NMR探头和盾牌反对电场
公开(公告)号：EP2095145B1
公开(公告)日：2013-08-14
申请号：EP07853386.6
申请日：2007-12-14
申请人： Agilent Technologies, Inc.
发明人： WITHERS, Richard S.
IPC分类号： G01R33/422 , G01R33/34
CPC分类号： G01R33/422 , G01R33/34007 , G01R33/34023 , G01R33/34069 , G01R33/34092

87. 发明公开

EP2618905A2 SYSTEM AND PROCESS FOR AN ACTIVE DRAIN FOR GAS-LIQUID SEPARATORS 有权
标题翻译：用于气液分离器主动排放的系统和方法
公开(公告)号：EP2618905A2
公开(公告)日：2013-07-31
申请号：EP11827390.3
申请日：2011-09-20
申请人： Agilent Technologies, Inc.
发明人： FOGELMAN, Kimber, D. , WIKFORS, Edwin, E. , BERGER, Terry, A.
IPC分类号： B01D15/40
摘要： A device includes a gas-liquid separator that receives and separates a biphasic pressurized flow stream and delivers flow to at least one exit port enriched in vapor phase composition and at least one exit port enriched in liquid phase composition. The device further includes a low restriction inlet conduit in communication with the separator exit port enriched in liquid phase composition, and a positive displacement pump having an inlet port in communication with the inlet conduit to receive flow from the gas-liquid separator and an outlet port in communication with an outlet conduit.
摘要翻译：一种有效地产生用于高低压气液分离器的主动排放装置和方法。本发明实现了来自分离器的可变体积和粘度液体馏分的确定性排放速率。其机制和方法从分离器产生流动路径，该流动路径显着有利于在宽范围的流速和粘度下控制液体流动，同时限制气体流动。本发明是一种优于使用压力，真空，隔离阀和/或被动限流器来实现分离器排水的常规系统的排水方法。这些实施方案主要涉及制备型超临界流体色谱法（SFC）和超临界流体萃取（SFE）领域。一个实施方案的优点允许将典型的HPLC系统经济转换为最新技术的超临界流体色谱（SFC）系统，对系统组分进行最小修改。

88. 发明公开

EP2599785A1 Novel methods for the synthesis and purification of oligomers 审中-公开
标题翻译：对于低聚物的合成和纯化的新方法
公开(公告)号：EP2599785A1
公开(公告)日：2013-06-05
申请号：EP12190465.0
申请日：2012-10-29
申请人： Agilent Technologies, Inc.
发明人： Lackey, Jeremy , Leproust, Emily Marine
IPC分类号： C07H21/04 , C07H23/00 , C07C237/00 , C07C13/45
CPC分类号： C07H23/00 , C07F9/2408 , C07F9/65586 , C07H21/04
摘要： A reagent for oligonucleotide synthesis or purification, wherein the reagent has a structure of:

X - C - L - H (Formula A)

wherein X is a phosphoramidite group, an H-phosphonate group, an acetal group, or an isocyanate; C is a direct bond or a cleavable adaptor represented by -C a -C b -; L is a hydrocarbyl chain; and H is a terminal alkyne or an activated cyclooctyne. The reagent of Formula (A) can be used in the synthesis and purification of oligonucleotides.
摘要翻译：一种用于寡核苷酸合成或纯化试剂，worin试剂具有以下结构：€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒX - C - L - ħ€ƒ€ƒ€ƒ€ƒ€ƒ（式A），其中X是亚磷酰胺基团，H-膦酸酯基团，缩醛基团，或以异氰酸酯; C是直接键合或由℃的-C b表示可裂解的适配器 - ; L是一个烃基链; 和H是末端炔或环辛激活。式（A）所述的试剂可以在寡核苷酸的合成和纯化中使用。

89. 发明公开

EP2567964A3 Monomer Compositions for the Synthesis of RNA, Methods of Synthesis, and Methods of Deprotection 有权
标题翻译： RNA合成，合成方法，和去保护的单体组合物
公开(公告)号：EP2567964A3
公开(公告)日：2013-05-22
申请号：EP12185461.6
申请日：2007-03-22
申请人： Agilent Technologies, Inc. , The Regents of the University of Colorado
发明人： Sierzchala, Agnieszka B. , Dellinger, Douglas J. , Dellinger, Geraldine F. , Caruthers, Marvin H. , Timar, Zoltan
IPC分类号： C07H21/02 , C07H19/12 , C07H19/16
CPC分类号： C07H19/12 , C07H19/16 , C07H21/02
摘要： 2'-O protected nucleotide monomers for the synthesis of RNA.

90. 发明授权

EP2327139B1 ROTOR DRIVE APPARATUS AND METHODS UTILIZING CENTER-FED RADIAL -OUTFLOW GAS 有权
标题翻译：转子驱动装置和方法与中心驱动的径向流出气体
公开(公告)号：EP2327139B1
公开(公告)日：2013-04-10
申请号：EP08826485.8
申请日：2008-07-28
申请人： Agilent Technologies, Inc.
发明人： STRINGER, John
IPC分类号： H02K7/00 , G01R33/30 , G01V3/00
CPC分类号： G01R33/307

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