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71. 发明公开

EP1748812A1 UNIT DOSE DRY POWDER INHALER 审中-公开
标题翻译：单位剂量干粉吸入器
公开(公告)号：EP1748812A1
公开(公告)日：2007-02-07
申请号：EP05746438.0
申请日：2005-05-26
申请人： Quadrant Technologies Ltd.
发明人： YOUNG, Matthew E. , HARRISON, Neil, Richard , KAY, Stuart Brian William , LIGOTKE, Michael W.
IPC分类号： A61M15/00 , B65D75/58
CPC分类号： A61M15/0028 , A61M15/0008 , A61M15/0031 , A61M15/0086 , A61M2202/064 , A61M2205/583 , A61M2205/6045
摘要： A unit dose dry powder inhaler (10) has a dose unit (36) within an inhaler housing (15). As the dose unit is pushed into the inhaler housing, a container (46) on the dose unit is opened, releasing a pharmaceutical powder (47) into the housing. The user inhales on a mouthpiece (16), drawing the powder and air into a dispersion chamber (22). The powder disperses in air, and the powder/air mixture is inhaled. The inhaler is inexpensive, compact, and simple to use.
摘要翻译：单位剂量的干粉吸入器（10）在吸入器壳体（15）内具有剂量单元（36）。当剂量单元被推入吸入器壳体时，剂量单元上的容器（46）被打开，将药粉（47）释放到壳体中。使用者在吸嘴（16）上吸气，将粉末和空气吸入弥散室（22）。粉末分散在空气中，粉末/空气混合物被吸入。吸入器价格低廉，结构紧凑，使用简单。

72. 发明授权

EP1200149B1 DRY POWDER INHALER 有权
标题翻译：干粉吸入器
公开(公告)号：EP1200149B1
公开(公告)日：2006-09-20
申请号：EP00960184.0
申请日：2000-07-21
申请人： MannKind Corporation
发明人： STEINER, Solomon, S. , POOLE, Trent , FELDSTEIN, Robert , FOG, Per, B.
IPC分类号： A61M15/00 , A61J3/07
CPC分类号： A61M15/0028 , A61M11/002 , A61M15/002 , A61M15/0023 , A61M16/0495 , A61M16/0825 , A61M2202/064 , A61M2205/073 , A61M2205/43 , A61M2205/6045 , A61M2206/16
摘要： Described is a dry powder inhaler comprising an intake section; a mixing section, and a mouthpiece. The mouthpiece is connected by a swivel joint to the mixing section, and may swivel back onto the intake section and be enclosed by a cover. The intake chamber comprises a special piston with a tapered piston rod and spring, and one or more bleed-through orifices to modulate the flow of air through the device. The intake chamber further optionally comprises a feedback module to generate a tone indicating to the user when the proper rate of airflow has been achieved. The mixing section holds a capsule with holes containing a dry powder medicament, and the cover only can open when the mouthpiece is at a certain angle to the intake section. The mixing section further opens and closes the capsule when the intake section is at a certain angle to the mouthpiece. The mixing section is a Venturi chamber configured by protrusions or spirals to impart a cyclonic flow to air passing through the mixing chamber. The mouthpiece includes a tongue depressor, and a protrusion to contact the lips of the user to tell the user that the DPI is in the correct position. An optional strorage section, with a cover, holds additional capsules. The cover for the mouthpiece, and the cover for the storage section may both be transparent, magnifying lenses. The capsules may be two-part capsules where each portion has apertures which correspond to apertures in the other half when each half is partially filted to the other half, and fully fitted to the other half. All the apertures may be closed when the two halves are rotated around their longitudinal axes with respect to each other. Each capsule may have a unique key on each half that only fits with a particular inhaler.
摘要翻译：描述了一种包括吸入部分的干粉吸入器; 一个混合部分和一个吹口。咬嘴通过旋转接头连接到混合部分，并且可以旋转回到吸入部分并且被盖子封闭。进气室包括一个带锥形活塞杆和弹簧的特殊活塞，以及一个或多个排气孔，用于调节通过该装置的空气流量。进气室进一步可选地包括反馈模块，以产生指示用户何时达到适当气流速率的音调。混合部分容纳带有包含干粉药物的孔的胶囊，并且仅当口部与吸入部分成一定角度时盖才能打开。当吸入部分与吸口成一定角度时，混合部分进一步打开和关闭囊体。混合部分是由凸起或螺旋构成的文氏管室，以对通过混合室的空气施加气旋流。该吹嘴包括一个压舌板和一个与用户的嘴唇接触的突起，以告诉使用者DPI处于正确的位置。一个可选的存储部分，带盖，可容纳额外的胶囊。用于咬嘴的盖子和用于存储部分的盖子都可以是透明的放大镜头。胶囊可以是两部分胶囊，其中每个部分具有与另一半中的孔对应的孔，当每个半部分被部分地过滤到另一半时，并且完全装配到另一半。当两半围绕它们的纵向轴线相对于彼此旋转时，所有的孔可以被关闭。每个胶囊在每一半上可以有一个唯一的钥匙，只适合特定的吸入器。

73. 发明公开

EP1370316A4 FLUID FILLED AMPOULES AND METHODS FOR THEIR USE IN AEROSOLIZERS 审中-公开
标题翻译：与液体的安瓿瓶和填充的方法供其使用在雾化器
公开(公告)号：EP1370316A4
公开(公告)日：2006-08-23
申请号：EP02725236
申请日：2002-03-19
申请人： AEROGEN INC
发明人： LOEFFLER JOSEPH P , POYNTER RICHARD Q , RAPP DAVID , KLIMOWICZ MICHAEL
IPC分类号： A61J1/06 , A61M15/00 , B05B17/06 , B65D1/09 , A61M16/00
CPC分类号： A61M15/0085 , A61J1/065 , A61J2205/10 , A61J2205/60 , A61M15/0028 , A61M15/0031 , A61M15/009 , A61M2205/6045 , A61M2205/6054 , B05B17/0607 , B65D1/095 , B65D2203/00 , Y10S206/828 , Y10S215/03
摘要： A fluid filled ampoule comprises an ampoule body having a top end, a bottom end and a sealed interior containing a liquid. A top tab is coupled to the top end and is removable to create a drain vent in the top end. A bottom tab is coupled to the bottom end and is removable to create a drain opening in the bottom end. A movable shroud is coupled to the top end and is disposed about the top tab. The shroud is movable to permit access to the top tab.

74. 发明公开

EP1520599A1 Swivel connector 失效
标题翻译：旋转连接器
公开(公告)号：EP1520599A1
公开(公告)日：2005-04-06
申请号：EP04023449.4
申请日：2004-10-01
申请人： Fisher & Paykel Healthcare Limited
发明人： White, Craig Karl , Van Beurden, Jason Peter
IPC分类号： A61M16/08
CPC分类号： A61M16/08 , A61M16/0069 , A61M16/0666 , A61M16/0683 , A61M16/0816 , A61M16/0825 , A61M16/109 , A61M16/1095 , A61M16/16 , A61M2016/0039 , A61M2205/3368 , A61M2205/6045 , F16L37/084 , Y10S285/914
摘要： A connector (1) for use with a conduit (3) to supply gases to a user (13) is disclosed. The connector (1) comprises a pair of connectors (22,23), adapted to fit together and swivel relative to one another. More particularly, the connector may comprise a female (36) and male (34) connector assemblies, adapted to be push fit together. The female connector (36) assembly preferably has an extended shoulder and a number of triangular guide slots (43,44), the slots being shaped so as to be wider at one end. The male connector assembly preferably comprises a male portion (37) and a sleeve (38) that when joined, cannot be easily separated by axial or torsional tension applied to either, but may rotate freely relative to each other. The sleeve (38) preferably has a number of guide ridges (41,42) running axially along its outside surface that slidably mate with the guide slots (43,44) on the female connector (36).

75. 发明公开

EP1511528A2 DRUG CONTAINER ENTRY MECHANISMS AND METHOD 审中-公开
标题翻译：药物TANK输入机制和程序
公开(公告)号：EP1511528A2
公开(公告)日：2005-03-09
申请号：EP03731217.0
申请日：2003-05-16
申请人： Scott Laboratories, Inc.
发明人： HICKLE, Randall, S.
IPC分类号： A61M5/32 , A61M5/00
CPC分类号： A61M5/142 , A61M5/14228 , A61M5/14232 , A61M5/162 , A61M5/1723 , A61M39/281 , A61M2005/1623 , A61M2205/12 , A61M2205/3386 , A61M2205/3553 , A61M2205/6045
摘要： The invention of this application relates generally to intravenous (IC) infusion of drugs to patients, and more particularly to aspects of an IV infusion system comprising an infusate cassette and an infusate container. The present invention provides a drug infusion cassette (150) that incorporates a strong vial spike (163) that may be non-metal, a means for sheathing (158) the spike when it is not in use, an anti-free flow device (168), and other beneficial features such as an air entrainment lockout mechanism, quality assurance tags, stopcocks made of soft material and means of securing tubing to the cassette with a minimum of individual parts. The drug cassette (150) can be used with an automated spiking mechanism comprising a motorized vial holder that holds a vial. The spike (163) remains sheathed if the drug cassette (150) is not fully engaged with a mating surface (200) of devices such as a pumping unit or a sedation and analgesia delivery system.

76. 发明公开

EP1498073A1 System und Verfahren zum Mischen von wenigstens vier Komponenten 有权
标题翻译：系统和方法，用于混合至少四种组分
公开(公告)号：EP1498073A1
公开(公告)日：2005-01-19
申请号：EP03405537.6
申请日：2003-07-15
申请人： Straumann Holding AG
发明人： Fehr, Daniel , Neidhardt, Astrid , Damm. Christian
IPC分类号： A61B17/00 , A61M5/19 , A61J1/00 , B65D81/32
CPC分类号： B65D81/325 , A61B2017/00495 , A61C5/62 , A61C5/64 , A61C5/68 , A61J1/201 , A61J1/2017 , A61J1/2055 , A61J1/2058 , A61J1/2065 , A61J1/2096 , A61M5/19 , A61M2205/6045
摘要： Ein System zum Mischen von vier Komponenten (K1, K2, K3, K4) weist eine erste Spritzenanordnung (10) und eine zweite Spritzenanordnung (20) auf. In den ersten und zweiten Spritzenanordnungen (10, 20) sind je wenigstens zwei Kammern (11, 12; 21, 22) zur Aufnahme je einer der Komponenten (K1, K2, K3, K4) enthalten. Jede Kammer der einen Spritzenanordnung (10) ist lösbar mit einer Kammer (21, 22) der anderen Spritzenanordnung (20) verbindbar. Durch Transfer der Komponenten (K1, K2) von der einen Spritzenanordnung (10) in Kammern (21, 22) der anderen Spritzenanordnung (20) werden die transferierten Komponenten (K1, K2) mit in dieser Kammer (21, 22) enthaltenen Komponenten (K3, K4) gemischt.
摘要翻译：一种用于混合四种组分（K1，K2，K3，K4）系统包括第一注射器组件（10）和第二注射器组件（20）。在第一和第二注射器组件（10，20）各自为至少两个腔室（11，12; 21，22），每个用于接收所述组件（K1，K2，K3，K4）包含的一个。注射器组件（10）中的每一个腔室可拆卸地连接到连接到另一注射器组件（20）的腔室（21，22）。通过以这种腔室传送在腔室中的一个注射器组件（10）的另一注射器组件的部件（K1，K2）（21,22）（20），所述传递部件（K1，K2）（21，22）包含组分（ K3，K4）混合。

77. 发明公开

EP1406547A1 SYRINGE AND NEEDLE FOR PREVENTING INADVERTENT DRUG INJECTION 有权
标题翻译：注射器和针头FOR拒绝毒品意外注射
公开(公告)号：EP1406547A1
公开(公告)日：2004-04-14
申请号：EP02750685.6
申请日：2002-07-12
申请人： Children's & Women's Health Centre of British Columbia
发明人： SHEPPARD, Ian, Graham , FORBES, Martin, John , FLADL, Theresia, Trevan , LI, Ivan, Yan-Yip , EMES, John, Hayward , DAVIS, Jeffrey, Howard , BARBOUR, Kathryn, Ann
IPC分类号： A61B17/34 , A61M5/00
CPC分类号： A61B17/3401 , A61M5/002 , A61M5/34 , A61M5/346 , A61M2205/6045
摘要： A spinal syringe and needle for preventing the inadvertent injection of an intravenous drug spinally includes a needle engagement extension on the spinal needle defining an opening of a first diameter, a syringe engagement extension on the spinal syringe defining an opening of a second diameter, the syringe engagement extension engageable with the needle engagement extension to operatively connect the needle to the syringe. The first and second diameters are dimensioned such that a surface of the syringe engagement extension is in frictional engagement with a surface of the needle engagement extension, the first diameter is substantially the same as the diameter of an opening defined by the engagement extension of a typical syringe and the second diameter is substantially the same as the diameter of an opening defined by the engagement extension of a typical needle. A system and method for preventing the inadvertent injection of an intravenous drug spinally and a spinal drug intravenously includes a spinal needle and a spinal syringe for holding and dispensing the drug to be injected spinally, the spinal syringe operatively connectable to the spinal needle. An intravenous syringe is provided for holding and dispensing the drug to be injected intravenously, the intravenous syringe operatively connectable to the intravenous needle. The intravenous needle cannot be operatively connected to the spinal syringe and the spinal needle cannot be operatively connected with the intravenous syringe thereby preventing the inadvertent injection of the drug in each syringe through an incorrect needle.

78. 发明公开

EP1354641A1 Liquid waste disposal and canister flushing system and method 失效
标题翻译：系统和方法液体废物处理和罐冲洗
公开(公告)号：EP1354641A1
公开(公告)日：2003-10-22
申请号：EP03077208.1
申请日：1997-12-02
申请人： Dornoch Medical Systems, Inc.
发明人： Dunn, James L. , Carty, Timothy A.
IPC分类号： B08B3/00 , B08B9/08 , B08B9/093 , A61M1/00
CPC分类号： B08B9/28 , A61B50/36 , A61M1/0001 , A61M1/0017 , A61M1/0096 , A61M2205/6045 , B08B9/0813 , B08B9/0826 , B08B9/093
摘要： A liquid waste disposal and canister flushing system includes a cabinet (6) with a sink (14k) for receiving the canister (4) and a subsink (141) for receiving a lower portion thereof. The subsink (141) is connected to a drain line (14o). A plunger subassembly (12) includes a plunger rod (92) and a stopper (95) which functions as a drain valve for the canister (4). An injection jet (34) is connected to water and cleaning solution sources (21, 39) and discharges diluted cleaning solution into the canister (4) for flushing same. The injection jet (34) engages the plunger subassembly (12) for ejecting the stopper (95) from a canister drain opening (12a). A control system (10) includes a programmable microprocessor (50) which can be programmed to provide drain and flush cycles of predetermined duration. A number of different container and accessory embodiments are disclosed. A method of liquid waste disposal and canister flushing utilizes the microprocessor (50) for delaying the flush cycle until completion of the drain cycle. The control system (10) can provide drain and flush cycles of predetermined durations, can monitor water pressure, flow rate and temperature, cleaning solution flow rate, holding tank neutralizer inputs and timing and other system parameters.
摘要翻译：一种液体废物处理和滤罐冲洗系统包括机柜（6）具有用于接收所述罐（4）和用于接收其下部一subsink（141）一个信宿（14K）。所述subsink（141）是连接到漏极线（140）。柱塞组件（12）包括柱塞杆（92）和作为用于所述罐（4）中的排放阀，其功能的止动件（95）。一种注射射流（34）连接到水和清洗液源（21，39）和放电稀释清洗液到罐（4），用于冲洗相同。喷射流（34）接合，用于从罐排水开口（12a）的喷射挡块（95）的柱塞组件（12）。一种控制系统（10）包括一个可编程的微处理器（50），它可以被编程以提供漏极和预定持续时间的冲洗周期。许多不同的容器和附件的实施例的光盘是游离缺失。液体废物处置和冲洗罐的方法，利用用于延迟所述冲洗循环，直到漏极周期完成的微处理器（50）。该控制系统（10）可以提供漏极和预定持续时间的冲洗循环，可监测水压力，流速和温度，清洗液流量，容纳槽中和剂投入和定时和其他系统参数。

79. 发明公开

EP1177807A3 Device and method of creating aerosolized mist of respiratory drug 失效
标题翻译：装置和方法用于从atmungserleichternden药物产生气溶胶雾
公开(公告)号：EP1177807A3
公开(公告)日：2003-10-22
申请号：EP01126125.2
申请日：1995-10-27
申请人： ARADIGM CORPORATION
发明人： Lloyd, Lester J. , Lloyd, Peter M. , Rubsamen, Reid M. , Schuster, Jeffrey A.
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61J7/0418 , A61M11/001 , A61M11/002 , A61M11/005 , A61M11/042 , A61M15/0051 , A61M15/008 , A61M15/0085 , A61M16/1075 , A61M2016/0021 , A61M2016/0039 , A61M2202/062 , A61M2205/52 , A61M2205/6045
摘要： A drug delivery device, comprising: a channel having a first opening into which air can be inhaled and a second opening from which a patient can withdraw air; a mechanism for applying physical force to formulation upon actuation; and an air-heating device which adds energy to air inhaled into the channel; wherein the device is a hand-held self-contained device having a total weight of 1 kilogram or less.

80. 发明公开

EP1304086A2 Behältnis für das Aufbringen einer dentalen Masse 有权
标题翻译：容器用于将牙科用组合物
公开(公告)号：EP1304086A2
公开(公告)日：2003-04-23
申请号：EP02019794.3
申请日：2002-09-05
申请人： Firma Ivoclar Vivadent AG
发明人： Reisinger, Michael
IPC分类号： A61C5/06 , B05C17/01
CPC分类号： B05C17/00509 , A61C5/62 , A61C2202/01 , A61M5/347 , A61M2205/6045 , A61M2205/6081 , B05C17/00516
摘要： Ein Behältnis lagert einer pastösen Masse für den Dentalbereich in einem Gehäuse (12). Das Gehäuse weist einen Anschluss auf, der mit einer Ausbringdüse (22) oder einer Verschlusskappe verbindbar ist, die druckfest und dicht an dem Gehäuse (12) befestigbar und von diesem lösbar sind. Die Masse aus dem Gehäuse ist ausbringbar und auftragbar, und die Ausbringdüse (22) weist eine Markierung (34,38,42) auf, die einer Markierung (32,36,40) auf dem Gehäuse entspricht.
摘要翻译：一种容器，存储在糊用于在壳体（12）牙科应用。该外壳具有一个端口可连接到分配喷嘴（22）或盖附接，压力抗性和密封到壳体（12）和可释放由其。质量可从壳体和可涂覆被排出，并且应用程序喷嘴（22）具有相应于所述外壳有标记（32,36,40）相关的标志物（34,38,42）。

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