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71. 发明公开

EP3439711A1 PERITONEAL DIALYSATE FLUID GENERATION SYSTEM 审中-公开
公开(公告)号：EP3439711A1
公开(公告)日：2019-02-13
申请号：EP17718245.8
申请日：2017-04-04
申请人： Medtronic, Inc.
发明人： MANDA, VenKatesh R. , GERBER, Martin T. , HOBOT, Christopher M.
IPC分类号： A61M1/16 , A61M1/28 , C02F1/00 , C02F1/02 , C02F1/28 , C02F1/32 , C02F1/44

72. 发明公开

EP3354298A3 GANGED MODULAR RECHARGING SYSTEM 有权
公开(公告)号：EP3354298A3
公开(公告)日：2018-10-31
申请号：EP18153940.4
申请日：2018-01-29
申请人： Medtronic, Inc.
发明人： GERBER, Martin T.
IPC分类号： A61M1/16 , B01J20/34
CPC分类号： A61M1/1696 , B01D15/203 , B01J20/0211 , B01J20/0292 , B01J20/20 , B01J20/3416 , B01J20/3433 , B01J20/3475
摘要： The invention relates to systems and methods for recharging sorbent materials and other rechargeable dialysis components. The systems and methods include rechargers, flow paths, and related components for connecting multiple rechargers together to sharing infrastructure and resources. The rechargeable dialysis components can include zirconium phosphate, zirconium oxide, and other sorbent cartridge materials including any combination thereof or any other rechargeable component of a dialysis system. Additionally, a single-use cartridge or a multi-use cartridge can be used in the present invention.

73. 发明公开

EP3354298A2 GANGED MODULAR RECHARGING SYSTEM 有权
公开(公告)号：EP3354298A2
公开(公告)日：2018-08-01
申请号：EP18153940.4
申请日：2018-01-29
申请人： Medtronic, Inc.
发明人： GERBER, Martin T.
IPC分类号： A61M1/16 , B01J20/34
CPC分类号： A61M1/1696 , B01D15/203 , B01J20/0211 , B01J20/0292 , B01J20/20 , B01J20/3416 , B01J20/3433 , B01J20/3475
摘要： The invention relates to systems and methods for recharging sorbent materials and other rechargeable dialysis components. The systems and methods include rechargers, flow paths, and related components for connecting multiple rechargers together to sharing infrastructure and resources. The rechargeable dialysis components can include zirconium phosphate, zirconium oxide, and other sorbent cartridge materials including any combination thereof or any other rechargeable component of a dialysis system. Additionally, a single-use cartridge or a multi-use cartridge can be used in the present invention.

74. 发明公开

EP3341042A1 AUTHENTICATION SYSTEM UTILIZED IN A SORBENT-BASED DIALYSIS SYSTEM FOR THERAPY OPTIMIZATION 审中-公开
公开(公告)号：EP3341042A1
公开(公告)日：2018-07-04
申请号：EP16840175.0
申请日：2016-08-26
申请人： Medtronic, Inc.
发明人： GERBER, Martin T. , BLOOMBERG, Daniel , LURA, David B. , MANDA, VenKatesh R.
IPC分类号： A61M1/16
CPC分类号： A61M1/1696 , A61M1/14 , A61M2205/3569 , A61M2205/3592 , A61M2205/52 , A61M2205/6009 , A61M2205/6018 , A61M2205/6054 , A61M2205/6072 , G06F19/00 , G16H20/40 , G16H40/63
摘要： A dialysis authentication and management system comprising at least one dialysis component having at least one authentication component affixed thereon. The dialysis component can be any one of a dialyzer, sorbent cartridge, recharger or any other dialysis component. The authentication component can be selected from the group of a radio-frequency identification marker, a bar code, a one-wire security component, and a wireless authentication component. The authentication system can ensure that all components used are in proper usable condition and/or certified. The system can also manage the recharging of rechargeable components, and optionally manage dialysis therapy.

75. 发明公开

EP3293513A1 FLUID SENSOR APPARATUS 有权
标题翻译：流体传感器装置
公开(公告)号：EP3293513A1
公开(公告)日：2018-03-14
申请号：EP17190081.4
申请日：2017-09-08
申请人： Medtronic, Inc.
发明人： Lura, David B. , Kelley, Shawn , GERBER, Martin T.
IPC分类号： G01N21/78 , G01N21/80
CPC分类号： G01N21/80 , A61M1/1601 , A61M1/28 , A61M2205/3306 , A61M2205/3324 , A61M2205/3368 , G01N21/6428 , G01N21/78 , G01N21/783 , G01N2021/7763 , G01N2201/062 , G01N2201/0627
摘要： The invention relates to a fluid sensor apparatus and a related sensor card for determining and/or monitoring a pH and/or solute concentration in a fluid. The fluid sensor apparatus can be used in any application requiring the detection of fluid components or concentrations of solutes, and in an exemplary embodiment, is used to detect ammonia concentration and/or pH in dialysis fluid. The fluid sensor apparatus has a camera, a light source positioned opposite to the camera, and a receiving slot for positioning a removable sensor card between the camera and the light source such that both sides of the sensor card are exposed to the sampled fluid.
摘要翻译：本发明涉及用于确定和/或监测流体中的pH和/或溶质浓度的流体传感器装置和相关的传感器卡。该流体传感器装置可以用于需要检测流体成分或溶质浓度的任何应用中，并且在示例性实施例中，用于检测透析流体中的氨浓度和/或pH。流体传感器装置具有照相机，与照相机相对定位的光源以及用于在照相机和光源之间定位可移除传感器卡的接收槽，使得传感器卡的两侧暴露于采样流体。

76. 发明公开

EP3293507A1 GAS BUBBLE DETECTOR 审中-公开
标题翻译：气泡检测器
公开(公告)号：EP3293507A1
公开(公告)日：2018-03-14
申请号：EP17190084.8
申请日：2017-09-08
申请人： Medtronic, Inc.
发明人： GERBER, Martin T. , LURA, David B , KELLEY, Shawn
IPC分类号： G01N15/02 , G01N21/53 , G01N21/85
CPC分类号： G06K9/00624 , A61M1/1658 , A61M1/3626 , G01N15/0227 , G01N21/53 , G01N21/80 , G01N21/85 , G01N33/0027 , G01N2015/0011 , G06K9/209
摘要： The invention relates to a gas bubble detector for determining gas bubbles in a fluid. The gas bubble detector can be used in any application requiring a determination whether gas bubbles exist in the fluid. The gas bubble detector has a photodetector, a light source, and a chamber in which the presence of gas bubbles are detected.
摘要翻译：本发明涉及用于确定流体中的气泡的气泡检测器。气泡检测器可用于需要确定流体中是否存在气泡的任何应用。气泡检测器具有光检测器，光源和检测气泡存在的腔室。

77. 发明授权

EP2144666B1 THERAPY ADJUSTMENT 有权
标题翻译：治疗调整
公开(公告)号：EP2144666B1
公开(公告)日：2017-09-27
申请号：EP08745918.6
申请日：2008-04-16
申请人： MEDTRONIC, INC.
发明人： GERBER, Martin T. , RONDONI, John C.
IPC分类号： A61N1/36 , G06F19/00
CPC分类号： G06F19/3418 , A61N1/36514 , A61N1/36542 , A61N1/3655 , A61N1/36557 , A61N1/36564 , A61N1/36571 , G06F19/00 , G06F19/3456 , G16H40/63
摘要： Systems and methods for adjusting a therapy delivered to a patient include detecting a value of at least one sensed patient parameter and adjusting a therapy program to accommodate different patient parameter values. A data structure including a plurality of patient parameter values and associated therapy programs may be stored within a medical device or a programming device. Upon detecting a patient parameter value, an associated therapy program from the data structure may be selected. If no therapy program is associated with the detected patient parameter value, an intermediate program that best suits the detected patient parameter value may be generated by interpolating between the most recently implemented therapy program and a stored therapy program. In some embodiments, the rate of shifting between parameters of two stored or interpolated therapy programs may be based on the rate of change of the patient parameter value over time.
摘要翻译：用于调整递送给患者的治疗的系统和方法包括检测至少一个感测患者参数的值并调整治疗程序以适应不同患者参数值。包括多个患者参数值和相关联的治疗程序的数据结构可以存储在医疗设备或编程设备内。在检测到患者参数值时，可以选择来自数据结构的相关治疗程序。如果没有治疗程序与检测到的患者参数值相关联，则可以通过在最近实施的治疗程序和存储的治疗程序之间插值来生成最适合检测到的患者参数值的中间程序。在一些实施例中，两个存储的或内插的治疗程序的参数之间的移动速率可以基于患者参数值随时间的变化率。

78. 发明公开

EP3160529A1 REPLENISHING UREASE IN DIALYSIS SYSTEMS USING UREASE POUCHES 审中-公开
标题翻译：用尿素袋清除渗透系统中的尿素
公开(公告)号：EP3160529A1
公开(公告)日：2017-05-03
申请号：EP15810804.3
申请日：2015-03-11
申请人： Medtronic, Inc.
发明人： GERBER, Martin T. , HOBOT, Christopher M.
IPC分类号： A61M1/14 , A61M1/16
摘要： An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis using urease pouches. The sorbent cartridge is configured to allow insertion of a urease pouch or injection of a urease solution into the sorbent cartridge containing a urease pouch. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.
摘要翻译：一种用于在吸附剂盒中补充脲酶的设备和方法，所述吸附剂盒用于使用尿素酶袋的吸附剂透析。吸附剂盒构造成允许尿素酶袋的插入或尿素酶溶液的注入到包含尿素袋的吸附剂盒中。吸附剂组件还可以包含其他可再充填的吸附剂材料，用于从用过的透析液中除去尿素以外的毒素。

79. 发明公开

EP2950843A1 SODIUM AND BUFFER SOURCE CARTRIDGES FOR USE IN A MODULAR CONTROLLED COMPLAINT FLOW PATH 有权
标题翻译：钠和缓冲源盒式磁带用在模块化控制的投诉流路
公开(公告)号：EP2950843A1
公开(公告)日：2015-12-09
申请号：EP14746799.7
申请日：2014-02-01
申请人： MEDTRONIC, INC.
发明人： MEYER, Thomas E. , LURA, David B. , PUDIL, Bryant J. , GERBER, Martin T.
IPC分类号： A61M1/14
CPC分类号： A61M1/3621 , A61M1/16 , A61M1/1605 , A61M1/165 , A61M1/1658 , A61M1/1666 , A61M1/3609 , A61M1/3627 , A61M2205/3317 , A61M2205/3324 , A61M2205/3334 , A61M2205/3368 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2230/65
摘要： Systems and methods for using a sodium chloride source and a buffer source such as sodium bicarbonate in a controlled compliant flow path to generate from water a physiologically compatible fluid having a suitable level of a sodium ion and/or a buffer for use in hemodialysis, hemodiafiltration and hemofiltration. The system has a conditioning flow path that has at least a salination valve or salination pump, and at least one container has at least one solute in excess of the solubility of that solute. At least one of the solutes is a buffer source or sodium chloride. The conditioning flow path is in fluid communication with a controlled compliant flow path. The conditioning flow path can selectively meter fluid into and out of the controlled compliant flow path.

80. 发明公开

EP2950841A1 FLUID CIRCUIT FOR DELIVERY OF RENAL REPLACEMENT THERAPIES 有权
标题翻译：佛罗里达州立大学维多利亚州VEN NIERENERSATZTHERAPIEN
公开(公告)号：EP2950841A1
公开(公告)日：2015-12-09
申请号：EP14746791.4
申请日：2014-02-01
申请人： MEDTRONIC, INC.
发明人： MEYER, Thomas E. , LURA, David B. , PUDIL, Bryant J. , GERBER, Martin T.
IPC分类号： A61M1/14 , A61M1/16 , A61M1/34
CPC分类号： A61M1/1621 , A61M1/1601 , A61M1/1652 , A61M1/1656 , A61M1/1658 , A61M1/1664 , A61M1/1668 , A61M1/3465 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649
摘要： A flow loop for hemodialysis, hemodiafiltration and hemofiltration for the treatment of pathological conditions such as End Stage Renal Disease (ESRD) that has a controlled compliant flow path for preparing fluids required for a hemodialysis therapy session from water. The controlled compliant flow path modifies water into any one of a solution for priming a hemodialysis system, a physiologically compatible solution for contacting blood, a physiologically compatible solution for infusion to a subject, and a solution for blood rinse back to a subject. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the flow path.
摘要翻译：用于血液透析，血液透析滤过和血液滤过的流动回路，用于治疗诸如终末期肾脏疾病（ESRD）的病理状况，其具有用于制备用于从水进行血液透析治疗所需的液体的受控顺应流动路径。受控制的顺应性流动路径将水改变成用于引发血液透析系统的溶液中的任何一种，用于接触血液的生理学相容溶液，用于输注到受试者的生理学相容溶液，以及用于血液冲洗回到受试者的溶液。受控制的柔性流动路径具有用于选择性地计量和计量来自流动路径的流体的装置。

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