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61. 发明公开

EP2284252A1 Surface-structured device for life-science applications 无效转让
标题翻译： OberflächenstrukturierteVorrichtungfürAnwendungen der Biowissenschaften
公开(公告)号：EP2284252A1
公开(公告)日：2011-02-16
申请号：EP09010463.9
申请日：2009-08-13
申请人： Sony DADC Austria AG
发明人： Lucic, Ivan , Kraushaar, Harald
IPC分类号： C12M1/20 , C12M1/22 , C12M1/24
CPC分类号： C12M25/06 , C12M23/02 , C12M23/20 , Y10T428/24355 , Y10T428/24479 , Y10T436/25375 , Y10T436/255
摘要： Embodiments of the invention relate a surface-structured device for life-sciences and a life-science method applying the surface-structured device. The surface-structured device has a substrate with a frontside surface corresponding to a first surface; and a plurality of protrusions arranged on the frontside surface. A shortest dimension of the protrusions at the junction from the protrusion to the frontside surface is smaller than 250 nm and at least a first group of the plurality of protrusions is arranged on a first planar area of the frontside surface in a first regular pattern in a plane of the first planar area of the frontside surface. Further embodiments relate to a stamper which may be used in the manufacturing method of the surface-structured device and a manufacturing method for surface-structured device.
摘要翻译：本发明的实施例涉及用于生命科学的表面结构设备和应用表面结构设备的生命科学方法。表面结构的装置具有基板，其具有对应于第一表面的前侧表面; 以及布置在前侧表面上的多个突起。在从突起到前侧表面的接合处的突起的最短尺寸小于250nm，并且至少第一组多个突起以第一规则图案布置在前侧表面的第一平面区域上在前侧表面的第一平面区域的平面。另外的实施例涉及可用于表面结构装置的制造方法的压模和表面结构装置的制造方法。

62. 发明公开

EP2251407A1 Disposable bioreactor, kit for the same and method for its production 有权转让
标题翻译： Einwegbioreaktor和Verfahren zu seiner Herstellung
公开(公告)号：EP2251407A1
公开(公告)日：2010-11-17
申请号：EP09006409.8
申请日：2009-05-12
申请人： EPPENDORF AG
发明人： Beese, Jochen , Eikelmann, Sven
IPC分类号： C12M1/06 , C12M1/24 , B65D43/02
CPC分类号： C12M23/32 , C12M23/28 , C12M23/38 , C12M27/02 , Y10T29/49
摘要： The present invention discloses a disposable bioreactor 1, consisting of a container 40 and a cap 10, which is connectable to the same and cannot be detached without destruction. For this purpose, the cap 10 comprises a retaining structure 20 with a plurality of locking arms 24 running in the lateral direction, while the locking arms 24 are adapted to be resiliently shortened in the longitudinal direction and to be locked vertically to the longitudinal direction in the container 40 by way of a retaining surface 28.
摘要翻译：本发明公开了一种一次性生物反应器1，其由容器40和帽10组成，其可连接到容器40并且不会被破坏而不能分离。为此，盖10包括具有在横向方向上延伸的多个锁定臂24的保持结构20，同时锁定臂24适于在纵向方向上弹性地缩短并且垂直于纵向方向锁定容器40通过保持表面28。

63. 发明授权

EP2085464B1 Laboratory vessel with shiftable vessel closure 有权
标题翻译：实验室器皿具有可调节血管闭塞
公开(公告)号：EP2085464B1
公开(公告)日：2010-11-17
申请号：EP08001918.5
申请日：2008-02-01
申请人： EPPENDORF AG
发明人： Beese, Jochen
IPC分类号： C12M1/24 , B01L3/14 , B65D55/16
CPC分类号： C12M23/38 , B01L3/50825 , B01L2200/087 , B01L2300/045 , C12M23/08

64. 发明公开

EP2180950A1 ALL-IN-ONE BIOLOGICAL SPECIMEN COLLECTING, TRANSPORTING AND ANALYZING DEVICE 有权
标题翻译： ALL-IN-ONE用于收集，运输和分析的生物样品
公开(公告)号：EP2180950A1
公开(公告)日：2010-05-05
申请号：EP08780215.3
申请日：2008-07-15
申请人： Nguyen, Phuong
发明人： CHARMASSON, Henri, J.A.
IPC分类号： B01L3/00 , C12M1/24 , G01N1/10
CPC分类号： B01L3/5029 , A61B10/0038 , A61B10/0096 , B01L3/5082 , B01L2300/042 , B01L2300/044 , B01L2300/048 , B01L2300/049 , B01L2300/0663 , B01L2300/0854 , B01L2400/0683 , C12M45/22 , G01N2001/027
摘要： A device (11) for collecting, shipping and analyzing a pathological specimen comprises a collector stick (19) projecting from the inside of the stopper (14) of a first tubular vessel (12) containing a solution (16). The bottom (15) of the first vessel (12) has an aperture (30) sealed by a frangible barrier (31). When the first vessel is inserted into a second vessel (22) containing a signaling element (29) and having a pintle (32) projecting inwardly from its bottom (33), the frangible barrier is broken by the pintle and part of the solution flows into the second vessel where it contacts the signaling element. A pin (39) projecting from the inside of a cap (36) for the second vessel punctures the stopper of the first vessel facilitating the flow of solution from the first to the second vessel. The analytical process can be performed in the absence of any contacting or manipulating of the first vessel and specimen collector by simply screwing the cap to its farthest position.

65. 发明公开

EP2141224A1 Stirred tank bioreactor 有权转让
标题翻译：搅拌罐生物反应器
公开(公告)号：EP2141224A1
公开(公告)日：2010-01-06
申请号：EP09161982.5
申请日：2009-06-04
申请人： Millipore Corporation
发明人： Kelly, James E. , Muldoon, Joseph William , Proulx, Stephen , Vigna, James J.
IPC分类号： C12M1/10 , C12M1/24
摘要： The present invention is a disposable bioreactor (2) formed of molded plastic. The bioreactor is presterilized and has a top (16) and body (22) sealed to each other. One or more ports (30a-c, 32a-c) are formed in the top and/or the side of the housing. Preferably at least one port is below the liquid/air level for the housing. The one or more ports that are below the liquid/air interface level may be used as sampling ports or access ports for probes or drains or supply ports for liquids or gases. The bioreactor provides a direct retrofit for the existing glass or steel assembly that utilizes the existing support structures and controls. The molded design overcomes issues of discontinuity, dead spots and the like due to its fixed dimensions that are built in by the molding process. Reproducable probe and other equipment location is also guaranteed through the use of the molded port features. The molded plastic allows for greater flexibility in material selection to reduce or eliminate lipid or cholesterol binding.
摘要翻译：本发明是由模制塑料形成的一次性生物反应器（2）。生物反应器被预先消毒并具有彼此密封的顶部（16）和主体（22）。一个或多个端口（30a-c，32a-c）形成在壳体的顶部和/或侧面中。优选地，至少一个端口低于壳体的液体/空气水平。低于液体/空气界面水平的一个或多个端口可以用作采样端口或用于探针或排放口的接入端口或用于液体或气体的供应端口。生物反应器为现有的玻璃或钢组件提供直接改造，利用现有的支撑结构和控制。由于模制工艺内置的固定尺寸，模制设计克服了不连续性，死角等问题。可再生探头和其他设备的位置也可以通过使用模制端口功能来保证。模制塑料允许在材料选择中具有更大的灵活性，以减少或消除脂质或胆固醇结合。

66. 发明授权

EP1969116B1 LABORATORY CULTURE FLASK WITH SNAP-ON CAP 有权
标题翻译：实验室培养带活塞SNAP LID
公开(公告)号：EP1969116B1
公开(公告)日：2009-11-25
申请号：EP06806908.7
申请日：2006-09-29
申请人： Pentacore International Holding
发明人： MENCHEL, Yariv , RAM, Yoav , MENCHEL, Lyron
IPC分类号： C12M1/24 , B01L3/14
CPC分类号： C12M23/08 , B01L3/50825 , C12M23/38
摘要： A combination of laboratory flask (2) and a cap (1) adapted for closure of said flask (2), wherein said laboratory flask (2) comprises a chamber and a neck (3) connected to said chamber and giving access to the interior of said chamber. Said cap (1) is made of a deformable elastic material and is adapted for being inserted on said neck (3) by a translation movement along said neck (3), the exterior surface of said neck (3) and the interior surface of said cap (1) being provided with at least two pairs of respective cooperating means (11-12, 11-12) arranged for producing a latching effect when the cap (1) is not deformed and an unlatching effect when the cap (1) is deformed, whereby the cap (1) can be inserted on or removed from said flask (2) by exerting a force on the cap (1) but not on the flask (2). The cap is preferably a snap-on cap, with a venting position.

67. 发明公开

EP2118259A1 DEVICE AND METHOD FOR REDUCING BUBBLE FORMATION IN CELL CULTURE 有权
标题翻译：装置和一种用于减少气泡教育在细胞培养
公开(公告)号：EP2118259A1
公开(公告)日：2009-11-18
申请号：EP08725509.7
申请日：2008-02-13
申请人： Corning Incorporated
发明人： KENNEY, David, A. , MARTIN, Gregory, R. , TANNER, Allison, J. , WALL, Joseph, C.
IPC分类号： C12M1/24 , C12M3/04 , B01L3/08
CPC分类号： B01L3/08 , C12M23/08 , C12M23/34 , C12M23/40 , C12M41/02
摘要： A device for minimizing the formation of bubbles or foam in cell culture is disclosed. The device has a manifold which directs the inflow of cells and cell culture media into a cell culture vessel so as to allow for displaced air or gas to vent from the cell culture vessel without mixing with the incoming cell culture media, thereby preventing the mixing of air and cell culture media and minimizing the formation of bubbles or foam inside the cell culture vessel.

68. 发明公开

EP2085464A1 Laboratory vessel with shiftable vessel closure 有权
标题翻译： Laborgefäßmit verstellbaremGefäßverschluss
公开(公告)号：EP2085464A1
公开(公告)日：2009-08-05
申请号：EP08001918.5
申请日：2008-02-01
申请人： EPPENDORF AG
发明人： Besse, Jochen
IPC分类号： C12M1/24 , B01L3/14 , B65D55/16
CPC分类号： C12M23/38 , B01L3/50825 , B01L2200/087 , B01L2300/045 , C12M23/08
摘要： The present invention pertains to vessels with a vessel closure, and in particular to laboratory vessels with a shiftable closure assembly. The laboratory vessel (10) comprises a container comprising an outwardly extending neck (18) with an opening which provides access to the interior of said container, at least one guiding device comprising a guided member and a guiding member, a closure assembly comprising a vessel closure (22) and at least one guided member which is part of said at least one guiding device, which is characterized in that said vessel closure (22) is arranged to be shifted away from said opening to provide access to the interior of the container, wherein said at least one guiding device guides the shifting of the closure assembly and retains it in connection with the container even in the position in which the vessel closure is removed from the opening.
摘要翻译：本发明涉及具有容器封闭的容器，特别涉及具有可移动封闭组件的实验室容器。实验室容器（10）包括容器，该容器包括具有开口的向外延伸的颈部（18），该开口提供对所述容器内部的通路，至少一个导向装置，包括被引导构件和导向构件，封闭组件包括容器封闭件（22）和至少一个被引导构件，所述至少一个被引导构件是所述至少一个引导装置的一部分，其特征在于，所述容器盖（22）被布置成从所述开口移开以提供通向容器内部的通路其中所述至少一个导向装置引导所述封闭组件的移动并将其与所述容器相连接，即使在所述容器封闭件从所述开口移除的位置中。

69. 发明授权

EP1817402B1 FLACON DE PREPARATION D'UNE SUSPENSION CYTOLOGIQUE 失效转让
标题翻译：活塞，生产细胞学暂停
公开(公告)号：EP1817402B1
公开(公告)日：2008-06-04
申请号：EP05823016.0
申请日：2005-11-28
申请人： Peltier, Eric
发明人： Peltier, Eric
IPC分类号： C12M1/24
CPC分类号： A61B10/00 , A61B10/02 , B01L3/5082 , B01L2300/0618 , B01L2300/0681
摘要： The invention concerns a flask for preparing a fixer-based cytological suspension, equipped with filtering means (4) at least partly immersed in the suspension, characterized in that the filtering means (4) are in the form of a basket-forming filtering material web, whereof the periphery (5) is fixed on the flask and whereof the center (6) is connected to a tube (7), extending towards the opening (2) of the flask, associated with position-maintaining means (8) in the flask and adapted to allow through a pipette for drawing the suspension.

70. 发明公开

EP1910509A1 DEVICE FOR PROCESSING A BIOLOGICAL AND/OR CHEMICAL SAMPLE AND METHOD OF USING THE SAME 审中-公开
标题翻译：设备用于加工生物和/或化学样品及其方法使用
公开(公告)号：EP1910509A1
公开(公告)日：2008-04-16
申请号：EP05766731.3
申请日：2005-07-19
申请人： Attogenix Biosystems Pte Ltd.
发明人： GHADESSY, Farid , TING, Dor Ngi , OVISO, Dominador Fortaleza, Jr. , LAU, Wen Jian , WANG, Hui
IPC分类号： C12M1/24 , C12M3/00 , B01L3/00 , A61B10/00 , G01N1/28
CPC分类号： G01N1/405 , B01L3/502 , B01L2300/0672 , B01L2300/069 , B01L2300/0832 , B01L2300/087 , B01L2400/0406 , B01L2400/0457 , B01L2400/0677 , B01L2400/0683 , G01N1/34 , Y10T436/143333 , Y10T436/25
摘要： The present invention relates to a device and an apparatus device for processing a biological and/or chemical sample. The device comprises at least one sample processing chamber having an inlet at a first end and a penetrable sealing layer at a second end that forms at least a part of an inner wall of the sample processing chamber. The sealing layer is adapted to seal off the sample processing chamber from the environment until said sealing layer is penetrated to form an outlet. The device and apparatus also includes an absorption layer, wherein upon penetration of said sealing layer, said absorption layer is in fluid contact with said sealing layer, and is capable of absorbing fluid released from said sample processing chamber, via the outlet. The present invention also relates to a fluid separation device. The fluid separation device comprises a penetrable sealing layer adapted to form a wall of a sample processing chamber of the device of the invention. The fluid separation device also comprises an absorption layer that is influid contact with the sealing layer and capable of absorbing fluid released from a sample processing chamber of the device.

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