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    • 66. 发明公开
    • Composition of mouth spray
    • VersprühbareMundwasser-Zusammensetzung
    • EP1013261A1
    • 2000-06-28
    • EP99310238.3
    • 1999-12-16
    • MITSUI & CO., LTD.
    • Maki, Hisako, Mitsui & Co. Ltd.Mori, Masao, Mitsui Norin Co. Ltd.Fukai, Katsuhiko, Mitsui Norin Co. Ltd.Hara, Yukihiko, Mitsui Norin Co. Ltd.
    • A61K7/26A61K7/16
    • A61K8/498A61K8/34A61K8/35A61K8/97A61Q11/00
    • A composition of mouth spray is provided, which comprises tea-polyphenol, 1-menthol and/or 1-carvone. A concentration of the tea-polyphenol in the composition of mouth spray is preferably from 10 to 20000 ppm. The tea-polyphenol is preferably at least one member selected from the group containing (+) -catechin, (-) -catechin, (+) -gallocatechin, (+) -epigallocatechin, (+) -gallocatechin gallate, (+) -epigallocatechin gallate, (-) -epicatechin, (-)-epicatechin gallate, (-) -catechin gallate, (-) -epigallocatechin, (-) -gallocatechin, (-) -epigallocatechin gallate, (-)-gallocatechin gallate, theaflavin monogallate A, theaflavin monogallate B, theaflavin digallate, and free theaflavin. Thus, the composition of mouth spray according to the present invention keeps a long duration of masking bad breath and of refreshing effect significantly. Moreover, the composition of mouth spray produces effects such as improvement in a refreshing feeling and pleasant aftertaste, cancellation of throat unpleasantness, and other useful effects that the tea-polyphenol has in nature.
    • 提供口腔喷雾组合物,其包含茶多酚,1-薄荷醇和/或1-丁酮。 口腔喷雾组合物中的茶多酚的浓度优选为10〜20000ppm。 茶多酚优选为选自由(+) - 儿茶素,( - ) - 儿茶素,(+) - 加西他汀,(+) - 表儿茶素,(+) - 格洛西汀没食子酸酯,(+) - ( - ) - 表儿茶素,( - ) - 表儿茶素没食子酸酯,( - ) - 儿茶素没食子酸酯,( - ) - 表没食子儿茶素,( - ) - 儿茶素,( - ) - 表没食子儿茶素没食子酸酯,( - ) - 单糖苷A,茶黄素单乙酸酯B,茶黄素二钠和游离茶黄素。 因此,根据本发明的口腔喷雾剂的组合物保持了长时间的掩盖口臭和显着的清爽效果。 此外,口腔喷雾的组成产生诸如改善清爽感和愉快的余味,消除咽喉不适等的作用,以及茶多酚本质上具有的其它有用效果。