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    • 61. 发明公开
    • MRI with arterial spin labeling in combination with a navigator sequence
    • MRT mit arteriellem Spinlabeling in Kombination mit einer Navigatorsequenz
    • EP2657718A1
    • 2013-10-30
    • EP12165755.5
    • 2012-04-26
    • Koninklijke Philips N.V.Philips Intellectual Property & Standards GmbH
    • Helle, MichaelBoernert, Peter
    • G01R33/563
    • G01R33/56366G01R33/5676
    • The invention relates to a method of MR imaging of at least a portion of a body (10) placed in a main magnetic field within the examination volume of a MR device. It is an object of the invention to enable MR imaging using arterial spin labeling (ASL) with reliable motion detection and motion compensation. The method of the invention comprises the following steps:
      - subjecting the portion of the body (10) to a spatially selective preparation sequence comprising one or more RF pulses and switched magnetic field gradients, which preparation sequence excites nuclear magnetization outside or inside an imaging region;
      - subjecting the portion of the body (10) to a spatially selective acquisition sequence comprising one or more RF pulses and switched magnetic field gradients, whereby MR signals are acquired from the imaging region;
      - subjecting the portion of the body (10) to a navigator sequence comprising one or more RF pulses and switched magnetic field gradients, which navigator sequence is applied at least once before, during or after the preparation sequence and/or before, during or after the acquisition sequence, whereby navigator signals are acquired from the portion of the body (10);
      - deriving translation and/or rotation data from the navigator signals, which translation and/or rotation data reflect motion of the body (10);
      - reconstructing a MR image from the acquired MR signals,
      wherein the translation and/or rotation data are used for adapting the preparation sequence and/or the imaging sequence and/or for motion correction during reconstruction of the MR image.
    • 本发明涉及放置在MR装置的检查体积内的主磁场中的身体(10)的至少一部分的MR成像方法。 本发明的目的是使用具有可靠运动检测和运动补偿的动脉自旋标记(ASL)来实现MR成像。 本发明的方法包括以下步骤: - 使身体(10)的一部分经受包括一个或多个RF脉冲和开关磁场梯度的空间选择性准备序列,该制备序列在成像区域外部或内部激发核磁化 ; - 对身体(10)的部分进行包括一个或多个RF脉冲和切换磁场梯度的空间选择性获取序列,从而从成像区域获取MR信号; - 将身体(10)的一部分经受包括一个或多个RF脉冲和切换磁场梯度的导航序列,该导航序列在制备序列之前和期间,和/或之前,期间或之后至少应用一次 获取序列,从而从身体(10)的部分获取导航信号; - 从导航信号导出翻译和/或旋转数据,哪个平移和/或旋转数据反映身体(10)的运动; - 从所获取的MR信号重构MR图像,其中所述平移和/或旋转数据用于在MR图像的重建期间适配准备序列和/或成像序列和/或运动校正。
    • 68. 发明公开
    • Vorrichtung und Verfahren zur Kontrastmittelmessung
    • EP2385388A1
    • 2011-11-09
    • EP11164699.8
    • 2011-05-04
    • Universitätsklinikum Freiburg
    • Kiselev, Valerij Dr.Gall, Peter Dr.Kellner, Elias
    • G01R33/563
    • G01R33/56366G01R33/5601
    • Die Erfindung betrifft eine Tomographieeinrichtung (3) zur Erzeugung von Magnetresonanz-(MR-) Bildern eines in einem Messvolumen der Tomographieeinrichtung (3) angeordneten Körperteils eines Lebewesens (1), mit einer ersten Messeinheit (4a) zur Aufnahme einer ortsaufgelösten zeitlichen Reihe von MR-Bildern des zu untersuchenden Körperteils, wobei die Zeitreihe von MR-Bildern den Durchgang eines in die Blutbahn des Lebewesens injizierten Kontrastmittels durch ein im zu untersuchenden Körperteil befindliches Organ darstellt, welche dadurch gekennzeichnet ist, dass mindestens eine weitere Messeinheit (4b) vorgesehen ist, die eine lokale Aufnahmespule umfasst, welche in der Nähe mindestens einer Arterie, die den in der Tomographieeinrichtung angeordneten Körperteil (2) des Lebewesens versorgt, die Konzentration des Kontrastmittels zeitaufgelöst und zeitgleich mit der Messung der durch die erste Messeinheit bestimmten zeitlichen Reihe von MR-Bildern misst. Durch diese Erfindung werden ein System und ein dazugehöriges Verfahren bereitgestellt, welche eine gleichzeitige Messung von großen Gefäßen und Gewebe mit ein und derselben Sequenz bei angepasstem dynamischem Bereich ermöglichen.
    • 装置(3)具有用于获取身体部分(2)的空间分辨的时间序列的磁共振图像的测量单元(4a),其中图像表示通过器官注入到生物体的血流中的造影剂的通过 位于身体部位。 另一个测量单元(4b)具有本地接收器线圈,其测量在时间分辨率附近的动脉附近的造影剂的浓度,并与图像的测量同时测量,其中后者单元被设计为表面线圈并连接到数据采集 渠道。 还包括用于操作层析成像装置的方法的独立权利要求。
    • 69. 发明公开
    • Apparatus for monitoring a system in which a fluid flows
    • 装置用于监测在其中流过流体的系统
    • EP2339303A3
    • 2011-08-10
    • EP10170834.5
    • 1997-01-21
    • Yeda Research and Development Co. Ltd.
    • Degani, Hadassa
    • G01F1/716G01R33/48G06T11/20
    • G06T11/206G01R33/5608G01R33/56366
    • Apparatus for monitoring a system in which a fluid flows and which is provided with a change in the system with time in space comprising:
      (a) monitoring means for monitoring a preselected place in the system for collecting data indicative of a system parameter (I(t)) that varies with time as a function of at least one variable (K,v) related to system wash-in and wash-out behavior;
      (b) first data processing means responsive to the monitoring means for receiving the collected data and processing same; wherein
      said first data processing means comprises means for receiving as further inputs a plurality of time points (t0, t1, t2) and a maximum of an intensity function (I(t1)-I(t0)/(I(t0)(t0-t1)) wherein said intensity function is indicative of the wash-in of the system parameter (I(t)) being monitored and further including:
      (1) division means for spatially dividing the preselected place in the system into spatial units;
      (2) determining means for determining for each spatial unit a value and the intensity function indicative of the wash-in behavior based on the collected data for each time point;
      (3) normalizing means for normalizing the intensity of each spatial unit based on the maximum intensity ;
      (4) colorizing means for colouring all spatial units one of a plurality of colors based on a color function indicative of the wash-out behavior;
      (5) arranging means for arranging all spatial units for all time points into a composite of the preselected space with each spatial unit correlated to a color hue/color intensity as determined in step (4).