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61. 发明公开

EP3121766A1 SUBSTANCE SOURCE 无效
标题翻译： SUBSTANZQUELLE
公开(公告)号：EP3121766A1
公开(公告)日：2017-01-25
申请号：EP16187682.6
申请日：2005-11-17
申请人： Clinical Designs Limited
发明人： Bacon, Raymond John
IPC分类号： G06M1/22 , G06M1/04 , A61M15/00 , G06M1/08
CPC分类号： A61M15/0076 , A61M15/0021 , A61M15/0025 , A61M15/0073 , A61M15/0075 , A61M15/008 , A61M15/009 , A61M16/12 , A61M16/20 , A61M2202/02 , A61M2202/04 , A61M2205/123 , G06M1/041 , G06M1/045 , G06M1/083 , G06M1/22
摘要： A source of a gaseous substance, an inner subassembly and an outer subassembly having an outer enclosure comprising, a counter (20) accommodated within the outer enclosure (11) for counting substance release displacements of the spout (4); and a counter actuation member arranged beside the spout (4) for displacement inwards to increment the counter (20), the outer subassembly having an overall length from the actuation member at the spout (4) to a pressurised-container reaction surface, which length decreases on substance release and having at least a first quiescent length and a second length at which counter incrementation is initiated, • the subassembly also having a tolerance adjusted connection of the cap (105) to the outer enclosure (11) set with respect to a use installation of the source, whereby the stroke between the first and second lengths of the respective subassemblies is compensated for synchronisation of substance release and count incrementation.
摘要翻译：气体物质的源，内部子组件和具有外壳的外部子组件，其包括容纳在外部外壳（11）内的计数器（20），用于计数喷嘴（4）的物质释放位移。以及设置在所述喷嘴（4）旁边以用于向内移位以增加所述计数器（20）的反作用致动构件，所述外部子组件具有从所述致动构件在所述喷口（4）处到加压容器反作用表面的总长度，减少物质释放并具有至少第一静止长度和开始反增加的第二长度，子组件还具有相对于盖子（105）设置的帽（105）与外壳（11）的公差调节连接源的使用安装，由此相应子组件的第一和第二长度之间的行程被补偿用于物质释放和计数递增的同步。

62. 发明授权

EP1449557B1 DISPENSING DEVICE KIT 有权
标题翻译：分发设备套件
公开(公告)号：EP1449557B1
公开(公告)日：2016-09-07
申请号：EP04012779.7
申请日：1999-01-13
申请人： Trudell Medical International
发明人： Blacker, Richard , Engelbreth, Daniel, K. , Schmidt, James N.
IPC分类号： A61M15/00 , G06M1/04 , G06M1/08 , G06M1/16
CPC分类号： A61M15/0071 , A61M15/0021 , A61M15/0065 , A61M15/0068 , A61M15/0075 , A61M15/0076 , A61M15/0081 , A61M15/009 , G06M1/041 , G06M1/083 , G06M1/163

63. 发明公开

EP3054920A2 DRY POWDER INHALER 无效
标题翻译：干粉吸入器
公开(公告)号：EP3054920A2
公开(公告)日：2016-08-17
申请号：EP14786419.3
申请日：2014-10-06
申请人： Teva Branded Pharmaceutical Products R&D, Inc.
发明人： DALVI, Mukul , TEE, Seah Kee
IPC分类号： A61K9/12 , A61M15/00 , A61K31/137 , A61K31/56
CPC分类号： A61M15/0008 , A61K9/0075 , A61K9/1623 , A61K31/137 , A61K31/56 , A61K31/569 , A61K31/57 , A61M15/00 , A61M15/0021 , A61M15/0025 , A61M15/0076 , A61M15/0078 , A61M15/0086 , A61M2202/064 , G01N33/15 , A61K2300/00
摘要： This invention provides a dry powder inhaler comprising: a dry powder medicament comprising fluticasone propionate, salmeterol xinafoate and a lactose carrier; wherein, the delivered dose of salmeterol per actuation is less than 50 μg; and wherein the dose provides a baseline-adjusted FEV1 in a patient of more than 150 mL within 30 minutes of receiving the dose. A method of treating a patient includes administering to a patient a dry powder medicament having fluticasone propionate, salmeterol xinafoate and a lactose carrier; wherein, the delivered dose of salmeterol per actuation is less than 50 μg; and wherein the dose provides a baseline-adjusted FEV1 in a patient of more than 150 mL within 30 minutes of receiving the dose.

64. 发明公开

EP2196234A4 METERED DOSE INHALER 审中-公开
标题翻译： DOSIERAEROSOL
公开(公告)号：EP2196234A4
公开(公告)日：2014-12-17
申请号：EP08834311
申请日：2008-09-26
申请人： OTSUKA PHARMA CO LTD
发明人： OI YOSHIHIRO , ADACHI SHINTARO , NAKAO TAKAAKI
IPC分类号： A61M15/00
CPC分类号： A61M15/009 , A61M15/0025 , A61M15/0065 , A61M15/0071 , A61M15/0073 , A61M15/0076 , G06M1/041 , G06M1/163 , G06M1/241

65. 发明授权

EP1680065B1 INDICATING DEVICE WITH WARNING DOSAGE INDICATOR 有权转让
标题翻译： INDIKATORVORRICHTUNG MIT DOSIS-WARNHINWEIS
公开(公告)号：EP1680065B1
公开(公告)日：2014-09-03
申请号：EP04789791.3
申请日：2004-10-28
申请人： Trudell Medical International
发明人： MORTON, Robert , LU, Winston
IPC分类号： A61M15/00
CPC分类号： A61M15/0076 , A61M15/0065 , A61M15/0073 , A61M15/0075 , A61M15/009
摘要： An indicating device suitable for indicating the number of dosages of a substance that have been dispensed from or remain in a container includes at least one first indicator member incrementally moveable to a plurality of positions and a second indicator member moveable in response to a predetermined number of movements of the at least one first indicator member. The at least one first indicator member includes primary dosage indicia adapted to indicate the number of dosages of substance that have been dispensed from or remain in the container. The second indicator member includes secondary dosage indicia adapted to indicate that less than a minimum predetermined number of dosages of substance remain in the container. In one preferred embodiment, the primary dosage indicia are configured as numerical indicia and the secondary dosage indicia are configured as color indicia. In another aspect, a device for dispensing dosages of a substance includes a dispenser housing and a container disposed in the dispenser housing. The indicating device is located adjacent to and is actuated by one or the other of the top or bottom of the container. A method for indicating the number of metered dosages of medicaments dispensed from or remaining in the container is also provided.
摘要翻译：适于指示从容器中分配或保留在容器中的物质的剂量数量的指示装置包括至少一个可递增地移动到多个位置的第一指示器构件，以及可响应于预定数量的所述至少一个第一指示器构件的运动。所述至少一个第一指示剂构件包括主要剂量标记，其适于指示已从或从容器分配的物质的剂量数。第二指示器构件包括适于指示小于预定数量的物质的物质残留在容器中的次级剂量标记。在一个优选的实施方案中，主要剂量标记被配置为数字标记，并且次级剂量标记被配置为颜色标记。在另一方面，用于分配物质剂量的装置包括分配器壳体和设置在分配器壳体中的容器。指示装置位于容器的顶部或底部中的一个或另一个附近并被致动。还提供了用于指示从容器中分配或保留在容器中的计量剂量的剂量的方法。

66. 发明公开

EP1838371A4 DISPENSING DEVICE 有权转让
标题翻译： ABGABEVORRICHTUNG
公开(公告)号：EP1838371A4
公开(公告)日：2014-04-02
申请号：EP06703451
申请日：2006-01-19
申请人： TRUDELL MEDICAL INT
发明人： LU WINSTON , MORTON ROBERT , PICKARD MARK , BALLES JOAQUIM
IPC分类号： A61M15/00 , B67D7/06 , A61J1/00 , A61M11/00 , A61M11/08 , B67D7/22 , B67D7/56 , B67D7/84
CPC分类号： A61M15/0073 , A61M11/08 , A61M15/0021 , A61M15/0025 , A61M15/0065 , A61M15/0068 , A61M15/007 , A61M15/0076 , A61M15/008 , A61M15/009 , A61M16/0816 , A61M16/20 , A61M2039/268 , A61M2205/27 , Y10T29/49826
摘要： A system of medicament dispensers includes a plurality of dispenser housings each having a unique first indicia and a plurality of containers each having a unique second indicia. The unique second indicia of each of the containers corresponds to one of the unique first indicia of a corresponding one of the dispenser housings. Methods for associating various containers and dispensers is also provided.
摘要翻译：药物分配器系统包括多个分配器壳体，每个分配器壳体具有唯一的第一标记和多个容器，每个容器具有唯一的第二标记。每个容器的唯一的第二标记对应于相应的一个分配器壳体的独特的第一标记之一。还提供了用于关联各种容器和分配器的方法。

67. 发明授权

EP1885415B1 DEVICE FOR DELIVERING MEDICAMENT 有权转让
标题翻译： DEVICE FOR药品监督管理局
公开(公告)号：EP1885415B1
公开(公告)日：2013-05-15
申请号：EP06733519.0
申请日：2006-05-22
申请人： SHL Group AB
发明人： KRONESTEDT, Victor , BRUNNBERG, Lennart , OLSON, Stephan , DEURELL, Tomas , KARLSSON, Anders
IPC分类号： A61M5/315 , A61M5/20 , A61M11/00 , A61M15/00
CPC分类号： A61M5/20 , A61M5/24 , A61M5/2448 , A61M5/3146 , A61M5/31535 , A61M5/31553 , A61M5/31556 , A61M5/3156 , A61M5/31568 , A61M5/31573 , A61M5/31583 , A61M5/31593 , A61M15/0045 , A61M15/0065 , A61M15/0068 , A61M15/007 , A61M15/0071 , A61M15/0076 , A61M15/0081 , A61M15/0091 , A61M2005/2013 , A61M2005/202

68. 发明授权

EP1922100B1 AN INHALER 有权
标题翻译：气雾
公开(公告)号：EP1922100B1
公开(公告)日：2012-11-07
申请号：EP06779326.5
申请日：2006-09-07
申请人： GLAXO GROUP LIMITED
发明人： PEARSON, Allen, John , RAND, Paul, Kenneth
IPC分类号： A61M15/00
CPC分类号： A61M15/009 , A61M15/0025 , A61M15/0076 , A61M15/0081 , A61M2205/276

69. 发明授权

EP1917108B1 ATOMISER COMPRISING A COUNTER AND AN END OF OPERATION LOCK 有权
标题翻译： EINENZÄHLERUND EINE BETRIEBSENDSPERRE UMFASSENDERZERSTÄUBER
公开(公告)号：EP1917108B1
公开(公告)日：2012-10-03
申请号：EP06776839.0
申请日：2006-08-14
申请人： Boehringer Ingelheim International GmbH
发明人： GESER, Johannes , METZGER, Burkhard P. , GOLBERG, Christian , SCHYRA, Michael , THOEMMES, Ralf , WESTMEIER, Birgit , SCHMIEDEL, Guido , KUNZE, Hubert , BOECK, Georg
IPC分类号： B05B11/00 , A61M15/00 , G06M3/02
CPC分类号： A61M15/0065 , A61M11/007 , A61M15/0026 , A61M15/0036 , A61M15/004 , A61M15/0066 , A61M15/0073 , A61M15/0076 , A61M15/0078 , A61M15/0081 , A61M2202/064 , A61M2205/273 , A61M2205/6045 , B05B11/0054 , B05B11/308 , B05B11/3091 , G06M3/02

70. 发明公开

EP2484395A2 Device for delivering medicament 有权转让
标题翻译： Vorrichtung zur Abgabe von Medikamenten
公开(公告)号：EP2484395A2
公开(公告)日：2012-08-08
申请号：EP12166782.8
申请日：2006-05-22
申请人： SHL Group AB
发明人： Kronestedt, Victor , Brunnberg, Lennart , Olson, Stephan , Deurell, Tomas , Karlsson, Anders
IPC分类号： A61M5/315 , A61M5/20 , A61M11/00 , A61M15/00
CPC分类号： A61M5/20 , A61M5/24 , A61M5/2448 , A61M5/3146 , A61M5/31535 , A61M5/31551 , A61M5/31556 , A61M5/3156 , A61M5/31568 , A61M5/31573 , A61M5/31583 , A61M5/31593 , A61M15/0045 , A61M15/0066 , A61M15/0068 , A61M15/007 , A61M15/0071 , A61M15/0073 , A61M15/0076 , A61M15/0091 , A61M2005/2013 , A61M2005/202 , A61M2005/2488
摘要： A device (2,100) for delivery of predetermined doses of liquid medicament, which device is adapted to be in a medicament delivery state and in a medicament non-delivery state, said device is adapted to comprise;
- a cartridge (10,103) adapted to contain the liquid medicament and a piston sealingly and slidably arranged in said cartridge;
- an energy accumulating member (26;114) adapted to accumulate energy in terms of at least one predetermined step when the device is in the medicament non-delivery state;
- an elongated threaded plunger rod (16,126) adapted to be arranged in the interior of the device;
- a plunger rod driving member (40;47;128) engaged to the threaded plunger rod (16;126) and adapted to be in a driven state when the device is in the medicament delivery state and adapted to be in a non-driven state when the device is in the medicament non-delivery state, wherein the rotation of the plunger rod driving member (40;47;128) due to the output torque of energy accumulating member (26;114) drives the threaded plunger rod (16;126) and allows said rod which is in contact with the piston, to be driven towards the proximal end of the cartridge with a predetermined distance and expels a predetermined dose of the liquid medicament from the cartridge; wherein
a bearing (41,46), coupled to or supported on an outer cover (55,48;108), is arranged and designed to effectively pick up forces acting on the proximal part of the device in the longitudinal direction thereof; whereby more of the accumulated energy that results from the stepwise rotational tensioning of the energy accumulating member (26;114) positioned at the distal end of the device, is brought to an efficient output torque.
摘要翻译：一种用于输送预定剂量的液体药物的装置（2,100），该装置适于处于药物输送状态并且处于药物非递送状态，所述装置适于包括： - 适于容纳液体药物的盒（10,103）和密封地且可滑动地布置在所述盒中的活塞; - 能量存储构件（26; 114），其适于当所述装置处于药物不输送状态时根据至少一个预定步骤累积能量; - 细长螺纹柱塞杆（16,126），其适于布置在所述装置的内部; - 柱塞杆驱动构件（40; 47; 128），其接合到所述螺纹柱塞杆（16; 126）并且当所述装置处于药物输送状态并适于处于非驱动状态时适于处于驱动状态当所述装置处于药物非输送状态时，由于能量存储构件（26; 114）的输出扭矩而导致的柱塞杆驱动构件（40; 47; 128）的旋转驱动螺纹柱塞杆（16 ; 126）并且允许与活塞接触的所述杆以预定距离朝着药筒的近端驱动，并从药筒排出预定剂量的液体药物; 其中联接到或支撑在外盖（55,48; 108）上的轴承（41,46）被布置和设计成有效地拾取作用在装置的纵向方向上的近端部分的力; 由此，位于设备的远端的能量存储部件（26; 114）的逐步旋转张紧产生的更多的积聚的能量被带到有效的输出转矩。

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