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61. 发明授权

EP2547217B1 INFANT NUTRITION FOR IMPROVING FATTY ACID COMPOSITION OF BRAIN MEMBRANES 有权
标题翻译：改善脑膜脂肪酸组成的营养物质
公开(公告)号：EP2547217B1
公开(公告)日：2017-07-19
申请号：EP11712043.6
申请日：2011-03-17
申请人： N.V. Nutricia
发明人： VAN DER BEEK, Eline Marleen , ABRAHAMSE-BERKEVELD, Marieke , SCHIPPER, Annemiek Lidewij , SPEELMANS, Gelske
IPC分类号： A23D7/01 , A23D9/05 , A23J7/00 , A61K31/201 , A61K31/683 , A23L33/00 , A23L33/12 , A23L33/115 , A23P10/35 , A23D9/013 , A61K9/00 , A61K31/202 , A61K31/685
CPC分类号： A61K31/202 , A23D7/011 , A23D9/013 , A23D9/05 , A23L33/115 , A23L33/12 , A23L33/40 , A23P10/35 , A23V2002/00 , A61K9/0087 , A61K31/201 , A61K31/575 , A61K31/683 , A61K31/685 , A61K2300/00 , A23V2200/322 , A23V2250/1882 , A23V2250/1868 , A23V2250/187 , A23V2200/224 , A23V2200/222 , A23V2200/254
摘要： The present invention relates to infant nutrition, in particular to infant nutrition comprising special lipid globules for improvement of the fatty acid composition in brain membranes.
摘要翻译：本发明涉及婴儿营养，特别涉及包含用于改善脑膜中脂肪酸组成的特殊脂质球的婴儿营养。

62. 发明公开

EP3185690A1 COMPRESSED SOLID MILK TABLETS AND METHOD FOR MAKING THE SAME 有权
标题翻译：压缩固体牛奶片及其制造方法
公开(公告)号：EP3185690A1
公开(公告)日：2017-07-05
申请号：EP15781447.6
申请日：2015-08-31
申请人： N.V. Nutricia , Eurotab Innovation
发明人： CHAURIN, Valérie Elvira Suzanne , VALK, Maarten , VAN DER HOEVEN, Martijn Johannes , COENEN, Gerardus Johannes
IPC分类号： A23C9/16 , A23C9/18 , B30B11/00
摘要： The present invention relates to compressed solid milk tablets, a method for producing the same and a modular system for carrying out said method. The method comprises: (a) compressing milk powder to obtain compressed solid milk units with a mechanical strength between 10 kPa and 300 kPa, (b) humidifying the compressed solid milk units by exposing them in a humidifying chamber to humid air having a relative humidity of more than 95% and a temperature between 60 and 90° C., wherein the humid air comprises condensed water vapour, and (c) drying the humidified and compressed solid milk units to obtain compressed solid milk tablets. The tablets obtained by this method have a mechanical strength between 20 kPa and 1000 kPa, a core/crust structure, wherein the crust comprises milk particles that are solidified and fused in parallel and perpendicular planes, relative to the tablet surface, and a friability of less than 5%.
摘要翻译：本发明属于营养领域，涉及压缩固体奶片及其生产方法和用于实施所述方法的模块化系统。制备压缩固体乳片的方法包括以下步骤：（a）压缩奶粉以获得机械强度在10kPa和300kPa之间的压缩固体乳单元，（b）通过将所述单元暴露于（c）干燥所述加湿和压缩的固体乳单元以获得压缩的固体，其中所述湿空气具有大于95％的相对湿度和在60和90℃之间的温度，其中所述湿空气包括冷凝的水蒸汽，以及牛奶片。通过该方法获得的片剂具有20kPa至1000kPa的机械强度，芯/壳结构，其中壳包含乳颗粒或由乳颗粒组成，所述乳颗粒相对于片剂表面在平行和垂直平面上固化并熔融，小于5％的脆碎度。

63. 发明公开

EP3171715A1 PREVENTION OR TREATMENT OF FOOD ALLERGY IN INFANTS AND TODDLERS 有权
标题翻译：德国柏林哥伦比亚广播电台BEHANDLUNG VON NAHRUNGSMITTELALLERGIEN
公开(公告)号：EP3171715A1
公开(公告)日：2017-05-31
申请号：EP15747243.2
申请日：2015-07-22
申请人： N.V. Nutricia
发明人： JEURINK, Prescilla , LOBATO-VAN ESCH, Betty
IPC分类号： A23L33/21 , A61K31/702 , A61K31/733 , A61P11/06 , A61P37/08
CPC分类号： A61K31/702 , A23L33/10 , A23L33/22 , A23L33/40 , A23V2002/00 , A61K31/733 , A23V2200/304 , A23V2200/3202 , A23V2250/156 , A23V2250/1882 , A23V2250/284 , A23V2250/5046 , A23V2250/54252 , A23V2250/612 , A23V2250/70
摘要： The invention pertains to the use of a non-digestible oligosaccharide in the manufacture of a composition for providing nutrition to an infant suffering from an increased risk of food allergy, preferably whey protein allergy; and/or reducing the risk of occurrence of or preventing whey protein allergy in an infant suffering from an increased risk of food allergy, particularly whey protein allergy. The infant is preferably at increased risk of trichothecene mycotoxin exposure, for instance by eating a lot of cereals.
摘要翻译：本发明涉及不可消化的寡糖在制备用于向患有食物过敏风险增加的婴儿提供营养的组合物的用途，优选乳清蛋白过敏; 和/或减少患有食物过敏风险增加的婴儿，特别是乳清蛋白过敏的发生或预防乳清蛋白过敏的风险。婴儿的头孢霉素毒素暴露的风险较高，例如吃大量的谷类食物。

64. 发明授权

EP2825062B1 PROCESS FOR PREPARING INFANT FORMULA 有权
标题翻译：制备婴儿配方的过程
公开(公告)号：EP2825062B1
公开(公告)日：2017-05-10
申请号：EP13709099.9
申请日：2013-03-13
申请人： N.V. Nutricia
发明人： VAN DEN BRENK, Joep , VAN DIJKE, Koen Cornelis , VAN DER STEEN, Adriana Martina Lamberta , MOONEN, Raoul Charles Johan , VAN BAALEN, Antonie
IPC分类号： A23L33/00 , A23L33/10 , A23D7/005 , A23D7/04
CPC分类号： A23L1/296 , A23D7/0053 , A23D7/011 , A23L33/115 , A23L33/40 , A23P10/40 , A23V2002/00
摘要： The present invention relates to a process for preparing a lipid and protein component-containing composition comprising large lipid globules, preferably coated with polar lipids, and to the compositions obtained thereby.
摘要翻译：本发明涉及一种制备含有脂质和蛋白质组分的组合物的方法，该组合物包含优选用极性脂质包覆的大脂质球，并涉及由此获得的组合物。

65. 发明授权

EP1841331B2 TEMPORALLY MEAL MENU FOR INFANTS 有权
标题翻译：用于婴儿的临时用餐菜单
公开(公告)号：EP1841331B2
公开(公告)日：2017-04-26
申请号：EP05824607.5
申请日：2005-12-23
申请人： N.V. Nutricia
发明人： BIJKERK, Elise , ALLES, Martine, Sandra
IPC分类号： A23L33/21 , A23L33/16 , A23L3/12 , A23L33/10 , A61P1/00
CPC分类号： A23L1/296 , A23L33/115 , A23L33/12 , A23L33/16 , A23L33/22 , A23L33/30 , A23L33/40 , A23V2002/00 , A23V2250/28 , A23V2250/1642 , A23V2250/1592 , A23V2250/1882

66. 发明公开

EP3152121A1 METHOD OF MANUFACTURING AND FILLING A PACKAGE AND CORRESPONDING PACKAGE 有权
标题翻译：用于生产和灌装包和相关包装
公开(公告)号：EP3152121A1
公开(公告)日：2017-04-12
申请号：EP15732975.6
申请日：2015-06-04
申请人： N.V. Nutricia
发明人： CRUSIUS, Sjors Floris
IPC分类号： B65D25/36 , B65D51/20 , B65B11/00 , B65D43/16 , B65D51/24 , B65B43/14 , B65B1/02 , B65B31/02
CPC分类号： B65B1/04 , B65B1/02 , B65B7/28 , B65B11/004 , B65B31/025 , B65B31/028 , B65B43/145 , B65D25/36 , B65D43/169 , B65D51/20 , B65D51/247 , B65D2251/0021 , B65D2251/0028 , B65D2251/009 , B65D2251/0093 , B65D2543/00194 , B65D2543/00296 , B65D2543/00435 , B65D2543/00527 , B65D2543/00537 , B65D2543/00611 , B65D2543/00685 , B65D2543/00722 , B65D2543/00787 , B65D2543/00842 , B65D2577/205 , B65D2577/2091
摘要： The invention also relates to a package for such a powdered nutritional product manufactured according to this method.
摘要翻译：因此本发明涉及一种包装，用于寻求粉状营养产品制造雅丁于该方法。

67. 发明公开

EP3145334A1 ENTERAL FORMULATIONS FOR PRETERM INFANTS COMPRISING OPTIMISED PHENYLALANINE INTAKE LEVELS 有权
标题翻译： ENTER ALE EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN EN
公开(公告)号：EP3145334A1
公开(公告)日：2017-03-29
申请号：EP14729065.4
申请日：2014-05-19
申请人： N.V. Nutricia
发明人： VAN DER BEEK, Eline Marleen , ABRAHAMSE-BERKEVELD, Marieke , VAN GOUDOEVER, Johannes Bernard , TELLER, Inga Christiane
IPC分类号： A23L33/17 , A23L33/00
CPC分类号： A23L33/40 , A23L33/17 , A23L33/175 , A23L33/185 , A23L33/19 , A23V2002/00 , A61K31/198 , A61K35/20 , A61K38/02
摘要： The present invention relates to enteral formulations for preterm infants (e.g., preterm formulas and human milk fortifiers) containing optimised intake levels of phenylalanine for the preterm infants. It particularly relates to a preterm formulation comprising a proteinaceous composition, wherein the preterm formulation (a) comprises 2.0-2.29 g phenylalanine per 100 g protein; (b) comprises 64.00-82.29 mg phenylalanine per 100 kcal; and/or (c) provides, or is formulated to provide phenylalanine in an amount of 80-96 mg/kg body weight per day.
摘要翻译：本发明涉及含有早产儿优选摄入量的苯丙氨酸的早产儿肠内制剂（例如，早产配方和人乳强化剂）。它特别涉及包含蛋白质组合物的早产调制剂，其中早产制剂（a）每100g蛋白质包含2.0-2.29g苯丙氨酸; （b）每100千卡包含64.00-82.29mg苯丙氨酸; 和/或（c）提供或配制为以每天80-96mg / kg体重的量提供苯丙氨酸。

68. 发明授权

EP2590521B1 NUTRITIONAL COMPOSITION FOR THE STIMULATION OF MUSCLE PROTEIN SYNTHESIS 有权
标题翻译：刺激肌肉蛋白质合成的营养组合物
公开(公告)号：EP2590521B1
公开(公告)日：2017-02-22
申请号：EP11736184.0
申请日：2011-07-06
申请人： N.V. Nutricia
发明人： JOURDAN, Marion-Eve Adeline , LUIKING, Yvette Charlotte , VERLAAN, George , TER BORG, Sovianne
IPC分类号： A23L33/175 , A23L33/155 , A23L33/00 , A61K31/198 , A61K31/59 , A61P21/06
CPC分类号： A61K31/593 , A23L33/155 , A23L33/175 , A23L33/40 , A23V2002/00 , A23V2200/316 , A23V2250/0614 , A23V2250/0628 , A23V2250/306 , A23V2250/71 , A61K31/198 , A61K31/59 , A61K31/592 , A61K2300/00 , A23V2200/302 , A23V2250/54252
摘要： The invention relates to the use of an anabolic amino acid derivative stimulus acting in combination with vitamin D for the manufacture of a medicament or nutritional composition for the prevention and/or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal.
摘要翻译：本发明涉及与维生素D组合起作用的合成代谢氨基酸衍生物刺激物在制备用于预防和/或治疗肌肉量，肌肉力量，肌肉功能中的任何一种的损失的药物或营养组合物中的用途，和身体功能，或其任何组合。

69. 发明公开

EP3114937A1 SOLID MILKS 有权转让
标题翻译： FESTE MILCHPRODUKTE
公开(公告)号：EP3114937A1
公开(公告)日：2017-01-11
申请号：EP16001115.1
申请日：2012-01-19
申请人： N.V. Nutricia , Eurotab
发明人： Rastello-De Boisseson, Marie , Bonneau, Eric , Coenen, Gerardus Johannes
IPC分类号： A23C9/18
CPC分类号： A23C9/18
摘要： The invention relates to a method for producing solid milks and to the products obtained with the aid of this method. The method comprises a compression step, then a moistening step, then a drying step. The compression step is carried out with a compaction ratio comprised between 50% and 80%. In the moistening step, water is sprayed on the outside surface of the said compressed and solid milk unit with an amount comprised between 0.1 mg and 8 mg per cm 2 of the area of the said outside surface, the duration of the moistening step being less than I s, to obtain a moistened solid unit having a moistened outside layer of at least two rows of milk particles. The drying step follows the moistening step less than 10s, the duration of the drying step being less than 30 s. The solid milk has a core/crust structure, the average thickness of the crust being at least the thickness of two rows of milk particles.
摘要翻译：本发明涉及一种生产固体乳的方法以及借助该方法获得的产品。该方法包括压缩步骤，然后是润湿步骤，然后进行干燥步骤。压缩步骤以50％至80％之间的压实率进行。在润湿步骤中，将水以所述外表面的每平方厘米面积的0.1mg至8mg之间的量喷洒在所述压缩和固体牛奶单元的外表面上，润湿步骤的持续时间较少以获得具有至少两排牛奶颗粒的湿润外层的润湿固体单元。干燥步骤在少于10秒的湿润步骤之后，干燥步骤的持续时间小于30秒。固体牛奶具有核/外壳结构，地壳的平均厚度至少为两排乳颗粒的厚度。

70. 发明公开

EP3099327A1 METHOD FOR REDUCING WHITE MATTER LESIONS, WHITE MATTER HYPERINTENSITIES (WMH), LEUKOARAIOSIS OR PERIVENTRICULAR WHITE MATTER DISEASE IN ELDERLY 审中-公开
标题翻译：用于减少脑白质病变的方法，超强度的白色物质（WMH），脑白质疏松症或PERIVENTRUKILÄRER脑白质病老年
公开(公告)号：EP3099327A1
公开(公告)日：2016-12-07
申请号：EP15705382.8
申请日：2015-02-02
申请人： N.V. Nutricia
发明人： VAN WIJK, Nick , HAGEMAN, Robert Johan Joseph , CANSEV, Mehmet
IPC分类号： A61K45/06 , A61K31/14 , A61K31/202 , A61K31/355 , A61K31/375 , A61K31/4415 , A61K31/519 , A61K31/683 , A61K31/685 , A61K31/7068 , A61K31/7072 , A61K31/714 , A61K33/04 , A61P25/00
CPC分类号： A61K31/7068 , A61K31/14 , A61K31/202 , A61K31/355 , A61K31/375 , A61K31/4415 , A61K31/519 , A61K31/683 , A61K31/685 , A61K31/7072 , A61K31/714 , A61K33/04 , A61K45/06 , A61K2300/00
摘要： The invention pertains to the use of one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof in the manufacture of a composition for treating, preventing or reducing the risk of occurrence of white matter lesions, white matter hyperintensities (WMH), Leukoaraiosis or periventricular white matter disease in elderly not suffering from a neurodegenerative disorder, preferably non-demented elderly and elderly not suffering from Alzheimer's Disease. It was found that with the compositions according to the invention Nogo-A protein levels could be controlled, particularly suppressed or reduced.
摘要翻译：本发明涉及使用一个或更多个尿苷和胞苷，或其盐，磷酸盐，酰基衍生物或其酯在用于治疗，预防或减少脑白质病变，白质高信号的发生的风险的组合物中的用途（ WMH）脑白质疏松症或老年不是从神经退行性疾病患脑白质病，最好非痴呆老人和老人没有从老年痴呆症。结果发现没有与该组合物根据本发明的Nogo-A蛋白质的水平可被控制，特别是抑制或减轻。

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