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61. 发明授权

EP1180045B1 INTRA-AORTIC BALLOON PUMP APPARATUS 有权
标题翻译：新加坡BALLONPUMPEINRICHTUNG
公开(公告)号：EP1180045B1
公开(公告)日：2012-03-07
申请号：EP00932531.7
申请日：2000-05-17
申请人： DATASCOPE INVESTMENT CORP.
发明人： NIGRONI, Paul , SARRAF, Lara
IPC分类号： A61M1/10
CPC分类号： A61M1/1086 , A61M1/1037 , A61M1/106 , A61M1/1072 , A61M1/125 , A61M2205/33 , A61M2205/3303 , A61M2230/04 , A61M2230/005
摘要： An intra-aortic balloon pump (IABP) (10) having improved automated electrocardiogram (ECG) based intra-aortic balloon deflation timing. Said IABP (10) capable of automatically determining to either deflate the intra-aortic balloon upon the detection of the next cardiac cycle (non-predictive deflation) or at an earlier point derived from predicting the occurrence of the next cycle (predictive deflation). This automated determination is based upon a quantitative assessment of the performance of the intra-aortic balloon pump (10) in predicting the prevailing cardiac rhythm. The accuracy of deflation based upon beat-to-beat interval prediction is scored relative to actual beat-to-beat interval. Once the cumulative prediction score of a predetermined number of historic beat-to-beat intervals reaches a predetermined threshold for non-predictive deflation, the non-predictive deflation mode is automatically activated. Scoring of beat predictions continues in this mode to signal when to switch back to predictive deflation.

62. 发明授权

EP1911484B1 Intra-aortic balloon catheter having a fiberoptic sensor 有权
标题翻译：主动脉内球囊导管与光纤传感器
公开(公告)号：EP1911484B1
公开(公告)日：2010-09-22
申请号：EP08001306.3
申请日：2001-12-10
申请人： DATASCOPE INVESTMENT CORP.
发明人： Shock, Robert B. , Williams, Jonathan , Walters, Daniel A.
IPC分类号： A61M25/00 , A61B5/0215 , A61M25/10
CPC分类号： A61M25/1006 , A61B5/0215 , A61M2025/0002 , A61M2025/0063 , A61M2025/018 , A61M2025/1093

63. 发明授权

EP1408823B1 MOBILE PATIENT MONITOR 有权
标题翻译：移动病人监护仪
公开(公告)号：EP1408823B1
公开(公告)日：2010-05-12
申请号：EP02748235.5
申请日：2002-07-23
申请人： DATASCOPE INVESTMENT CORP.
发明人： SAPER, Lawrence , KINAST, Eric
IPC分类号： A61B5/00 , A61B5/0402
CPC分类号： A61B5/0006 , A61B2560/0412

64. 发明公开

EP1982742A3 Intra-aortic balloon catheter having a fiberoptic sensor 审中-公开
公开(公告)号：EP1982742A3
公开(公告)日：2008-11-12
申请号：EP08014159.1
申请日：2001-12-10
申请人： DATASCOPE INVESTMENT CORP.
发明人： Shock, Robert B. , Williams, Jonathan , Walters, Daniel A.
IPC分类号： A61M25/00 , A61B5/0215 , A61M25/10
CPC分类号： A61M25/1006 , A61B5/0215 , A61B5/1459 , A61M2025/0002 , A61M2025/0063 , A61M2025/018 , A61M2025/1093
摘要： An intra-aortic balloon catheter (10) having a fiberoptic pressure sensor (22) embedded in the tip (20 and 104).

65. 发明授权

EP1409057B1 Intra-Aortic balloon catheter having a fiberoptic sensor 有权
标题翻译：主动脉内球囊导管与光纤传感器
公开(公告)号：EP1409057B1
公开(公告)日：2008-09-24
申请号：EP01270357.5
申请日：2001-12-10
申请人： DATASCOPE INVESTMENT CORP.
发明人： SCHOCK, Robert, B. , WILLIAMS, Jonathan , WALTERS, Daniel, A.
IPC分类号： A61M25/00 , A61B5/02
CPC分类号： A61M25/1006 , A61B5/0215 , A61M2025/0002 , A61M2025/0063 , A61M2025/018 , A61M2025/1093
摘要： An intra-aortic balloon catheter (10) having a fiberoptic pressure sensor (22) embedded in the tip (20 and 104).

66. 发明公开

EP1917362A1 METHODS AND KITS FOR SENSE RNA SYNTHESIS 审中-公开
标题翻译：方法和药盒抽样RNA合成
公开(公告)号：EP1917362A1
公开(公告)日：2008-05-07
申请号：EP06802382.9
申请日：2006-08-24
申请人： DATASCOPE INVESTMENT CORP.
发明人： GETTS, Robert, C. , SENSINGER, Kelly
IPC分类号： C12P19/34 , C07H21/02 , C07H21/04
CPC分类号： C12P19/34
摘要： Methods and kits are provided for performing sense RNA synthesis. The sense RNA molecules can be used in various research and diagnostic applications, such as gene expression studies involving nucleic acid microarrays.

67. 发明公开

EP1664350A4 METHOD FOR SMALL VOLUME NUCLEIC ACID SYNTHESIS 审中-公开
标题翻译：方法对于核酸的小批量合成
公开(公告)号：EP1664350A4
公开(公告)日：2007-10-10
申请号：EP04789156
申请日：2004-09-27
申请人： DATASCOPE INVESTMENT CORP
发明人： KADUSHIN JAMES M
IPC分类号： C07H21/00 , C07H21/04 , C12M1/36 , C12P19/34 , C12Q20060101 , C12Q1/68
CPC分类号： C12Q1/6837 , C12Q2565/1025 , C12Q2563/179 , C12Q2525/313
摘要： A method for synthesis of nucleic acids, with particular use for synthesis of cDNA. The method allows application of the cDNA to a microarray without the need for concentration or purification of the cDNA post-cDNA synthesis.

68. 发明公开

EP1663342A4 DIALYSIS CATHETER WITH STIFFNER 审中-公开
标题翻译：透析导管支具仪
公开(公告)号：EP1663342A4
公开(公告)日：2007-09-12
申请号：EP04781813
申请日：2004-08-20
申请人： DATASCOPE INVESTMENT CORP
发明人： AMARASINGHE CHANAKA , BATES JAMES
IPC分类号： A61M1/36 , A61M20060101 , A61M1/28 , A61M3/00 , A61M5/158 , A61M23/00 , A61M25/00
CPC分类号： A61M25/0026 , A61M1/3661 , A61M5/1582 , A61M25/0029 , A61M25/0068 , A61M25/007 , A61M2025/0031 , A61M2025/0037 , A61M2025/0063 , A61M2025/0073
摘要： A double lumen continuous flow dialysis needle (1) and cannula (20) having a contiguous lumens (2, 3) of different lengths, the shorter lumen acting as blood intake lumen and the longer as the blood return lumen, each lumen (2, 3) having a beveled edge (4, 5) sloping outwardly and away from the needle (1) which can be inserted percutaneously and which minimizes the possibility of mixing cleansed blood with blood entering the intake lumen.

69. 发明公开

EP1812600A2 METHODS FOR DETECTION OF MICRORNA MOLECULES 有权转让
标题翻译：检测方法的微RNA分子
公开(公告)号：EP1812600A2
公开(公告)日：2007-08-01
申请号：EP05817084.6
申请日：2005-11-02
申请人： DATASCOPE INVESTMENT CORP.
发明人： GETTS, Robert, C. , KADUSHIN, James , BOWERS, Jessica
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/04
CPC分类号： C12P19/34 , C12Q1/6809 , C12Q2565/501 , C12Q2525/191 , C12Q2563/179 , C12Q2525/207 , C12Q2525/173
摘要： Methods and kits are provided for the production and use in microarray assays of labeled miRNA molecules and labeled cDNA molecules complementary to miRNA molecules.

70. 发明公开

EP1746940A2 SURGICAL STAPLING SYSTEM 审中-公开
标题翻译：手术夹，系统
公开(公告)号：EP1746940A2
公开(公告)日：2007-01-31
申请号：EP05749767.9
申请日：2005-05-17
申请人： DATASCOPE INVESTMENT CORP.
发明人： FONTAYNE, Diego, Y.
IPC分类号： A61B17/04
CPC分类号： A61B17/115 , A61B17/072 , A61B17/1155 , A61B17/12013 , A61B2017/1107 , A61B2017/1157 , A61F2/06 , A61F2002/061 , A61F2002/065 , A61F2002/9517
摘要： A system is provided for joining two tubular structures by a surgical stapling procedure. The system includes a series of sizers (900), a specifically designed graft (10, 50), a loading unit (100) , a wand (300) , a surgical loop (400) and a stapling instrument (500). The sizers are for determining the diameter of a target aorta and the availability of a sufficient transected aortic length to perform a stapling procedure. The loading unit holds the graft in position in the body and deploys a circumferential line of staples (150) through the graft and an overlapping end of the aorta. The graft may include a side port (20) by which the loading unit holds the graft during the stapling procedure, and which may be closed once the stapling procedure has been completed. The wand may be used to introduce the loading unit and graft into the body, to position them within the transected aorta, and to hold them in place during the application of the surgical loop. The surgical loop may include a band (416) formed from a flexible material and having a width greater than its thickness so as to facilitate the formation of an annular loop. With the surgical loop holding the aorta and graft in relative overlapping positions, the wand may be removed from the loading unit and the stapling instrument may be assembled thereto. The stapling instrument includes a plurality of anvils (518a, 518b, 518c) which may be closed to form a circle overlying the aorta, and a trigger mechanism (670, 802) for firing the staples. When fired, the staples are deployed radially outward through the graft and aorta, whereupon their free ends are bent inwardly by staple returns (528) on the anvils. As a result, a plurality of staples may be simultaneously deployed quickly and accurately in a circumferential pattern so as to join together two tubular structures. The system may be used in either an open surgical procedure or laparascopically.

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