专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

51. 发明公开

EP1084116A1 CYCLOHEXENONDIOXOTHIOCHROMANOYL-DERIVATE 审中-公开
标题翻译： CYCLOHEXENONDIOXOTHIOCHROMANOYL衍
公开(公告)号：EP1084116A1
公开(公告)日：2001-03-21
申请号：EP99923435.4
申请日：1999-04-22
申请人： BASF AKTIENGESELLSCHAFT
发明人： WITSCHEL, Matthias , LANGEMANN, Klaus , VON DEYN, Wolfgang , MISSLITZ, Ulf , BAUMANN, Ernst , ENGEL, Stefan , MAYER, Guido , NEIDLEIN, Ulf , WAGNER, Oliver , GÖTZ, Roland , OTTEN, Martina , WESTPHALEN, Karl-Otto , WALTER, Helmut
IPC分类号： C07D335/06 , C07D339/08 , C07D409/08 , A01N43/18 , A01N43/32
CPC分类号： C07D335/06 , A01N43/08 , A01N43/18 , A01N43/36 , A01N43/54 , A01N43/56 , A01N43/653 , A01N43/80 , A01N43/84 , C07D339/08 , C07D409/08
摘要： The invention relates to cyclohexenondioxothiochromanoyl derivatives of formula (I) wherein the variables have the following meanings: X is oxygen, sulphur, S=O, S(=O)2, CR4R5, C=O or C=NR6; R1 is hydrogen, nitro, halogen, cyano, alkyl, alkyl halide, alkoxy, halogenalkoxy, alkylthio, halogenalkylthio, alkylsulfinyl, halogenalkylsulfinyl, alkylsulfonyl, halogenalkylsulfonyl, optionally substituted aminosulfonyl or optionally substituted sulfonylamino; R2 is alkyl, alkyl halide, alkoxy or halogenalkoxy; R3 is hydrogen, alkyl or halogen; and R4, R5 are hydrogen, nitro, halogen, cyano, alkyl, alkyl halide, alkoxy, halogenalkoxy, alkylthio, halogenalkylthio, alkylsulfinyl, halogenalkylsulfinyl, alkylsulfonyl, halogenalkylsulfonyl or substituted amino; or R?4 and R5¿ together form a chain which can be substituted and/or interrupted by oxygen or sulphur; or an optionally substituted methylide group; l is 0 to 4; R7 is substituted (3-oxo-1-cyclohexen-2-yl)-carbonyl or substituted (1,3-dioxo-2-cyclohexyl-methylides. The invention also relates to the agriculturally usable salts of said derivatives, to methods for producing the derivatives, to substances containing them, and to the use of the derivatives or substances containing them for combating undesirable plants.
摘要翻译：（I）的环己烯酮二氧代二氢苯并噻喃酰基衍生物，其中各变量具有以下含义：卤素，烷基，烷基卤，烷氧基，卤代烷氧基，烷硫基，卤代烷硫基，烷基亚磺酰基，卤代烷基亚磺酰基，烷基磺酰基，卤代烷基磺酰基，任选取代的氨基磺酰基或任选取代的磺酰基氨基; R2是烷基，烷基卤，烷氧基或卤代烷氧基; R3是氢，烷基或卤素; 硝基，卤素，氰基，烷基，烷基卤，烷氧基，卤代烷氧基，烷硫基，卤代烷硫基，烷基亚磺酰基，卤代烷基亚磺酰基，烷基磺酰基，卤代烷基磺酰基或取代的氨基; 或R 4和R 5'一起形成可被氧或硫取代和/或插入的链; 或任选取代的甲基基团; l是0到4; R7是取代的（3-氧代-1-环己烯-2-基） - 羰基或取代的（1,3-二氧代-2-环己基 - 甲基化物）。本发明还涉及所述衍生物的农业上可使用的盐，衍生物，含有它们的物质，以及使用衍生物或含有它们的物质来对付不需要的植物。

52. 发明授权

EP0618193B1 Dérivés bicycliques azotés, en tant qu'inhibiteurs de prolyl-endopeptidase 失效
标题翻译：双环衍生物缝合织物含有作为脯氨酰内肽酶抑制剂
公开(公告)号：EP0618193B1
公开(公告)日：1998-10-21
申请号：EP94400579.2
申请日：1994-03-17
申请人： ADIR ET COMPAGNIE
发明人： de Nanteuil, Guillaume , Portevin, Bernard , Remond, Georges , Lepagnol, Jean , Heidet, Véronique
IPC分类号： C07D209/42 , A61K31/395 , C07D453/06 , C07D409/08
CPC分类号： C07D409/08 , C07D209/42 , C07D453/06

53. 发明授权

EP0431580B1 Substituted cyclohexanols as central nervous system agents 失效
标题翻译：取代的环己与中枢神经系统的影响。
公开(公告)号：EP0431580B1
公开(公告)日：1995-03-08
申请号：EP90123291.8
申请日：1990-12-05
申请人： WARNER-LAMBERT COMPANY
发明人： Caprathe, Bradley William , Smith, Sarah Jane , Jaen, Juan Carlos , Wise, Lawrence David
IPC分类号： C07D213/74 , A61K31/44 , C07D409/12 , C07D417/12 , C07D401/10 , C07D401/12 , C07D211/82 , C07D405/12
CPC分类号： C07D211/82 , C07D213/74 , C07D213/82 , C07D401/08 , C07D401/12 , C07D405/12 , C07D409/08 , C07D409/12 , C07D417/12

54. 发明公开

EP0613465A1 1,3-SUBSTITUTED CYCLOALKENES AND CYCLOALKANES AS CENTRAL NERVOUS SYSTEM AGENTS 失效
标题翻译： 1,3-取代的环烯烃和环烷烃中枢神经系统的影响。
公开(公告)号：EP0613465A1
公开(公告)日：1994-09-07
申请号：EP92925105.0
申请日：1992-11-05
申请人： WARNER-LAMBERT COMPANY
发明人： CAPRATHE, Bradley, William , DOWNING, Dennis, Michael , JAEN, Juan, Carlos , JOHNSON, Stephen, Joseph , SMITH, William, John, III , WISE, Lawrence, David , WRIGHT, Jonathan , WUSTROW, David, Juergen
IPC分类号： C07D , A61K31 , A61P9 , A61P13 , A61P15 , A61P25 , A61P43 , C07D211 , C07D213 , C07D239 , C07D295 , C07D317 , C07D401 , C07D405 , C07D409 , C07D417
CPC分类号： C07D213/74 , C07D211/70 , C07D295/03 , C07D401/08 , C07D405/08 , C07D409/04 , C07D409/08
摘要： Cycloalcanes et cycloalkylènes 1,3-substitués de formule (I): Z-CH2-Y, dans laquelle Z représente (a), (b), (c) ou (d), Y représente (e) ou (f) et R et m sont décrits dans le descriptif. Cette invention concerne donc ces composés ainsi que leurs procédés de préparation et des compositions pharmaceutiques contenant lesdits composés qui sont utiles comme agent du système nerveux central et qui sont tout particulièrement utiles comme agents dopaminergiques, neuroleptiques et antihypertensifs et dans le traitement des affections liées à hyperprolactinèmie et des troubles du système nerveux central.

57. 发明授权

EP2780324B1 HETEROCYCLIC CARBOXAMIDES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE TYPE 10A 有权
标题翻译：杂环化合物羧酰胺抑制剂抑制剂磷酸二酯酶类型10A
公开(公告)号：EP2780324B1
公开(公告)日：2017-05-17
申请号：EP12781349.1
申请日：2012-11-08
申请人： Abbvie Deutschland GmbH & Co. KG , AbbVie Inc.
发明人： GENESTE, Hervé , OCHSE, Michael , DRESCHER, Karla , DINGES, Jürgen , JAKOB, Clarissa
IPC分类号： C07D217/26 , C07D237/32 , C07D401/06 , C07D401/12 , C07D401/14 , C07D417/12 , C07D471/04 , A61K31/472 , A61K31/502 , A61K31/4375 , A61P25/00
CPC分类号： C07D217/26 , A61K31/47 , C07D217/24 , C07D237/32 , C07D401/06 , C07D401/12 , C07D401/14 , C07D409/08 , C07D409/12 , C07D413/06 , C07D417/06 , C07D417/12 , C07D471/04
摘要： The present invention relates to compounds which are inhibitors of phosphodiesterase type 10A and to their use for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders.
摘要翻译：本发明涉及作为10A型磷酸二酯酶抑制剂的化合物及其用于制备药物的用途，因此其适用于治疗或控制选自神经障碍和精神疾病的医学病症，以改善与此类症状相关的症状疾病和降低这种疾病的风险。

59. 发明公开

EP2902402A1 WATER-SOLUBLE PHOTOCHROMIC MOLECULE 审中-公开
标题翻译：水溶性光铬合金分子
公开(公告)号：EP2902402A1
公开(公告)日：2015-08-05
申请号：EP13837714.8
申请日：2013-09-06
申请人： Rikkyo Educational Corporation , Josho Gakuen Educational Foundation
发明人： TOKIWA, Hiroaki , IRIE, Masahiro , IKEDA, Kiyoshi , OTSUBO, Tadamune
IPC分类号： C07H15/26
CPC分类号： C07H15/26 , C07D333/38 , C07D333/54 , C07D409/08 , C09K9/02
摘要： A diarylethene compound having high water-solubility is provided, and the compound is a diarylethene compound of formula (I)

wherein, Sg is a monovalent sugar-type residue consisting of a sugar-type compound (in which some of hydroxyl groups may be protected) selected from a group consisting of a six-membered ring sugar, a five-membered ring sugar, cyclitol and oligosaccharides containing a six-membered ring sugar, a five-membered ring sugar, or cyclitol and excluding an hydroxyl group;
U is -(CH 2 )n-, -CH 2 -U'-, or -C(=O)- (wherein, n is an integer of 1 to 5, U' is a C1-C10 alkyl group binding to Ar); and
Ar is a group represented by formula (A1) or (A2);

wherein,
X is S, SO 2 , NR 3 (R 3 is a C1-C3 alkyl group) or O,
R is C1-C4 alkyl group,
R 1 and R 2 are independently a C1-C3 alkyl group,
a is 0 or 1, b is an integer of 0-3, and
* represents a bond with U);
Y is a hydrogen atom or a halogen atom;
m is an integer of 5-7.

60. 发明公开

EP2760831A1 VIRAL REPLICATION INHIBITORS 审中-公开
标题翻译： VIRENREPLIKATIONSHEMMER
公开(公告)号：EP2760831A1
公开(公告)日：2014-08-06
申请号：EP12775463.8
申请日：2012-09-26
申请人： Katholieke Universiteit Leuven
发明人： BARDIOT, Dorothée , CARLENS, Gunter , DALLMEIER, Kai , KAPTEIN, Suzanne , McNAUGHTON, Michael , MARCHAND, Arnaud , NEYTS, Johan , SMETS, Wim , KOUKNI, Mohamed
IPC分类号： C07D209/14 , C07D401/08 , C07D401/12 , C07D401/14 , C07D403/08 , C07D403/10 , C07D403/12 , C07D405/12 , C07D409/08 , C07D409/12 , C07D413/08 , C07D413/12 , C07D417/14 , C07D471/04 , C07D487/04
CPC分类号： C07D487/04 , C07D209/14 , C07D401/06 , C07D401/08 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/08 , C07D403/10 , C07D403/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/08 , C07D409/12 , C07D413/06 , C07D413/08 , C07D413/12 , C07D417/14 , C07D471/04 , C07D495/04 , C07D498/04 , C07D513/04
摘要： The present invention relates to a series of novel compounds, methods to prevent or treat viral infections in animals by using the novel compounds and to said novel compounds for use as a medicine, more preferably for use as a medicine to treat or prevent viral infections, particularly infections with RNA viruses, more particularly infections with viruses belonging to the family of the Flaviviridae, and yet more particularly infections with the Dengue virus. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the novel compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of viral infections. The invention also relates to processes for preparation of the compounds.
摘要翻译：本发明涉及一系列新化合物，通过使用新化合物预防或治疗动物中的病毒感染的方法和用作药物的所述新化合物，更优选用作治疗或预防病毒感染的药物，特别是RNA病毒的感染，更特别是属于黄病毒科的病毒感染，更特别是登革热病毒的感染。本发明还涉及新化合物的药物组合物或组合制剂，用作药物的组合物或制剂，更优选用于预防或治疗病毒感染。本发明还涉及化合物的制备方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式