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51. 发明公开

EP1053328A2 PLANT HAVING ALTERED ENVIRONMENTAL STRESS TOLERANCE 审中-公开
标题翻译：植物具有改变的环境压力公差
公开(公告)号：EP1053328A2
公开(公告)日：2000-11-22
申请号：EP99905527.0
申请日：1999-01-28
申请人： MICHIGAN STATE UNIVERSITY
发明人： STOCKINGER, Eric, J. , JAGLO-OTTOSEN, Kirsten , ZARKA, Daniel , GILMOUR, Sarah, Jane , JIANG, Cai-Zhong , FROMM, Michael , THOMASHOW, Michael, F.
IPC分类号： C12N15/29 , C07K14/415 , C12N5/10 , A01H5/00 , A01N65/00
CPC分类号： C07K14/395 , C07K14/415 , C12N15/8216 , C12N15/8222 , C12N15/8237 , C12N15/8273
摘要： A transformed plant is provided which comprises one or more environmental stress tolerance genes; a DNA regulatory sequence which regulates expression of the one or more environmental stress tolerance genes; a sequence encoding a binding protein capable of binding to the DNA regulatory sequence and inducing expression of the one or more environmental stress tolerance genes; and a recombinant promoter which regulates expression of the gene encoding the binding protein. A method for altering an environmental stress tolerance of a plant is also provided which comprises the steps of transforming a plant with a promoter which regulates expression of at least one copy of a gene encoding a binding protein capable of binding to a DNA regulatory sequence which regulates one or more environmental stress tolerance genes in the plant; expressing the binding protein encoded by the gene; and stimulating expression of at least one environmental stress tolerance gene through binding of the binding protein to the DNA regulatory sequence.
摘要翻译：提供了包含一种或多种环境胁迫耐受性基因的转化植物; 调节一种或多种环境胁迫耐受性基因表达的DNA调节序列; 编码能够结合DNA调节序列并诱导一种或多种环境胁迫耐受性基因表达的结合蛋白的序列; 和调节编码结合蛋白的基因表达的重组启动子。还提供了用于改变植物的环境胁迫耐受性的方法，其包括用启动子转化植物的步骤，所述启动子调节编码能够结合调控序列的DNA结合蛋白的基因的至少一个拷贝，所述DNA调节序列调节植物中的一种或多种环境胁迫耐受基因; 表达由该基因编码的结合蛋白; 并且通过结合蛋白与DNA调节序列的结合来刺激至少一种环境胁迫耐受性基因的表达。

52. 发明公开

EP1038330A1 COMPOSITE ELECTROLYTE CONTAINING SURFACE MODIFIED FUMED SILICA 失效
标题翻译： WITH表面改性煅制二氧化硅的复合电解质
公开(公告)号：EP1038330A1
公开(公告)日：2000-09-27
申请号：EP98932801.8
申请日：1998-06-22
申请人： NORTH CAROLINA STATE UNIVERSITY , MICHIGAN STATE UNIVERSITY
发明人： KHAN, Saad, A. , FEDKIW, Peter, S. , BAKER, Gregory, L. , FAN, Jiang , RAGHAVAN, Srinivasa, R. , HOU, Jun
IPC分类号： H01M10/40 , H01M6/22 , C08K9/04 , C09C1/30 , C08F292/00
CPC分类号： H01M10/052 , C01P2004/50 , C01P2006/40 , C01P2006/90 , C08F292/00 , C09C1/3072 , H01M4/621 , H01M6/168 , H01M6/22 , H01M10/0565
摘要： A composite electrolyte comprises (a) surface modified fumed silica filler, wherein the surface modified fumed silica comprises polymerizable groups on the surface thereof, the polymerizable groups being bonded to each other such that the surface modified fumed silica filler is crosslinked in a three-dimensional structure; (b) a dissociable lithium salt; and (c) a bulk medium which contains the surface modified fumed silica filler and the dissociable lithium salt. An electrochemical cell comprises an anode, a cathode, and a composite electrolyte dispersed between the anode and cathode.

53. 发明公开

EP0942997A1 CHIMERIC LTB VACCINES 失效
标题翻译： CHIMERIC LTB疫苗
公开(公告)号：EP0942997A1
公开(公告)日：1999-09-22
申请号：EP97949404.0
申请日：1997-11-12
申请人： MICHIGAN STATE UNIVERSITY
发明人： BAGDASARIAN, Michael , IRELAND, James
IPC分类号： A61P37 , C07K14 , A61K38 , A61K39
CPC分类号： C07K14/245 , A61K38/00 , A61K39/00 , C07K14/575 , C07K2319/00
摘要： A chimeric protein formed of a small peptide antigen inserted into an exposed surface region of the B subunit of heat-labile enterotoxin of E. coli useful as an immunogenic vaccine composition.
摘要翻译：由小肽抗原形成的嵌合蛋白质插入用作免疫原性疫苗组合物的大肠杆菌热不稳定肠毒素B亚单位的暴露表面区域。

54. 发明公开

EP0877561A1 COMPOSITION AND METHOD FOR PRODUCING A SALTY TASTE 失效
标题翻译：组合物和方法用于生产咸味
公开(公告)号：EP0877561A1
公开(公告)日：1998-11-18
申请号：EP97905635.0
申请日：1997-01-30
申请人： MICHIGAN STATE UNIVERSITY
发明人： BERGLUND, Kris, A. , ALIZADEH, Hasan
IPC分类号： A23L1 , C07C55 , C07C229
CPC分类号： C07C55/10 , A23L27/45 , A23L33/175 , C07C229/26 , Y10S426/804
摘要： A physical mixture which consists essentially of compositions of lysine monohydrochloride and potassium chloride alone or admixed with small amounts of succinic acid in particular weight ratios which have a salty taste comparable to table salt (sodium chloride) is described. The mixtures mask the bitter aftertaste of the potassium chloride and can provide dietary lysine which is an essential amino acid.

55. 发明授权

EP0636279B1 BRANCHED POLYHYDROXYALKANOATE POLYMER SALT ELECTROLYTIC COMPOSITIONS AND METHOD OF PREPARATION 失效
标题翻译：电解质组合基于对于支聚羟基脂肪酸酯和方法及其
公开(公告)号：EP0636279B1
公开(公告)日：1998-06-03
申请号：EP94904451.5
申请日：1993-12-14
申请人： MICHIGAN STATE UNIVERSITY
发明人： REUSCH, Rosetta, N. , REUSCH, William, H.
IPC分类号： H01M6/18 , H01B1/12 , C08K3/16
CPC分类号： H01M6/181 , C08K3/16 , C08L67/04 , H01B1/122 , C08L71/00
摘要： Compositions and method for providing a solid conductive electrolyte composition containing a polyhydroxyalkanoate (PHA) and a salt of a conductive metal are described. The PHA is biodegradable and biocompatible and provides a basis for batteries which are more environmentally degradable. Naturally occurring polymers including polyhydroxybutyrate (PHB) and polyhydroxyvalerate (PHV) can be used to prepare the compositions.

56. 发明公开

EP0840784A1 METHOD OF PRODUCING AND PURIFYING ENZYMES 失效
标题翻译：方法对于制备和纯化的酶
公开(公告)号：EP0840784A1
公开(公告)日：1998-05-13
申请号：EP96903565.0
申请日：1996-01-22
申请人： MICHIGAN STATE UNIVERSITY
发明人： DEITS, Thomas, L.
IPC分类号： C12N15 , C07K14 , C12N1 , C12N9 , C12N11 , C12P21 , C12R1
CPC分类号： C07K14/32 , C07K2319/00 , C07K2319/61 , C12N9/2471 , C12N11/02 , C12N15/62 , C12N15/75 , C12Y302/01023
摘要： A method of producing and purifying an enzyme which comprises selecting a spore forming host organism, preparing a genetic construct consisting of a DNA sequence encoding the desired enzyme and a DNA sequence directing synthesis of the desired enzyme during sporulation, inserting the genetic construct into the host organism, culturing the transformed host organism under sporulating conditions to obtain host organism spores with the enzyme integrally associated to the spores, and then treating the host organism and enzyme combination to remove any impurities, if necessary. The free enzyme can be obtained by cleaving the connection between the host organism and the enzyme. The combination of the enzyme and host organism is both a stabilized and an immobilized enzyme preparation.

57. 发明公开

EP0822268A1 Process for depositing adherent diamond thin films 失效
标题翻译： Verfahren zur Erzeugung einer haftenden Diamantbeschichtung
公开(公告)号：EP0822268A1
公开(公告)日：1998-02-04
申请号：EP96112277.7
申请日：1996-07-30
申请人： MICHIGAN STATE UNIVERSITY
发明人： Ulczynski, Michael J. , Asmussen, Jes , Reinhard, Donnie K.
IPC分类号： C23C16/26 , C23C16/44
CPC分类号： C23C16/274 , C23C16/277 , C23C16/452
摘要： A process for depositing an adherent polycrystalline diamond thin film on a substrate, particularly a silicon or glass material, by chemical vapor deposition (CVD) at 1 to 15 torr and low temperatures of the substrate of between about 350 to 600°C using hydrogen and methane and optionally carbon dioxide. The substrate being placed adjacent to the plasma. The substrate has diamond particles deposited on it or is polished with diamond particles prior to CVD. The process produces films which are clear and adherent. The films are particularly useful on silicon wafers with integrated circuits.
摘要翻译：一种通过化学气相沉积（CVD）在1至15托和衬底的低温下使用氢和约350至600℃之间沉积粘附多晶金刚石薄膜的方法，特别是硅或玻璃材料，甲烷和任选的二氧化碳。衬底被放置在与等离子体相邻的位置。衬底上沉积有金刚石颗粒，或在CVD之前用金刚石颗粒抛光。该过程产生清晰和粘附的膜。这些膜在具有集成电路的硅晶片上特别有用。

58. 发明公开

EP0817781A1 ALKALI METAL FORMONONETIN AND METHOD OF MYCORRHIZAL STIMULATION 失效
标题翻译：碱性金属蛋白酶抑制剂和霉菌刺激的方法
公开(公告)号：EP0817781A1
公开(公告)日：1998-01-14
申请号：EP97903816.0
申请日：1997-01-16
申请人： MICHIGAN STATE UNIVERSITY
发明人： NAIR, Muraleedharan, G. , SAFIR, Gene, R. , SCHUTZKI, Robert, E. , NIEMIRA, Brendan, A.
IPC分类号： A01G31 , A01N43 , A01N63 , C07D311 , C12N1
CPC分类号： C07D311/36 , A01N43/16 , A01N63/04 , A01N2300/00
摘要： Compositions of an alkali metal formononetinate, particularly potassium and sodium, for stimulating the growth of mycorrhizal fungi which colonize the plant and in turn stimulate growth of the plant. The results are improved over formononetin.
摘要翻译：碱金属芒柄花碱，特别是钾和钠的组合物，用于刺激寄生在植物上的菌根真菌的生长，并且反过来刺激植物的生长。结果比芒柄花素有所改善。

59. 发明授权

EP0502146B1 MAREK'S DISEASE HERPESVIRUS DNA SEGMENT ENCODING GLYCOPROTEIN gE 失效
标题翻译：马立克氏病疱疹病毒的DNA区段WHICH糖蛋白gE的CODES
公开(公告)号：EP0502146B1
公开(公告)日：1997-11-19
申请号：EP91915865.9
申请日：1991-08-19
申请人： MICHIGAN STATE UNIVERSITY
发明人： VELICER, Leland, F. , BRUNOVSKIS, Peter , COUSSENS, Paul, M.
IPC分类号： C12N15/38 , C07K14/055 , C12N7/04 , A61K39/255 , C12N15/86 , C12Q1/70
CPC分类号： C07K14/005 , A61K38/00 , C12N2710/16322
摘要： DNA encoding glycoproteins gD, gI and gE from Marek's disease herpesvirus is described. The DNA is useful for probes to detect the DNA in the herpesvirus, for expression to produce the glycoproteins that can be used for producing the antibodies which specifically recognize the three glycoprotein antigens, and in the case of the latter two genes, for potential insertion sites for foreign genes and as possible sites for gene inactivation to attenuate MDV field isolates for vaccine purposes.

60. 发明公开

EP0788301A1 METHOD FOR REDUCING ABRASION OF TURFGRASS 失效
标题翻译：减少磨盘磨损的方法
公开(公告)号：EP0788301A1
公开(公告)日：1997-08-13
申请号：EP95916967.0
申请日：1995-04-20
申请人： MICHIGAN STATE UNIVERSITY
发明人： ROGERS, John, N. , VANINI, Joseph, Timothy
IPC分类号： A01G13 , E01C13
CPC分类号： E01C13/083
摘要： A method for topdressing turfgrass on an activity field with only solid elastomeric particles is described. The method produces turfgrass which has enhanced color and health even when there is extensive abrasion of the grass through use of the field.
摘要翻译：描述了在仅具有固体弹性体颗粒的活动场上追施草皮草的方法。该方法生产的草坪草即使在通过使用田地对草的广泛磨损时也具有增强的颜色和健康。

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