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41. 发明授权

EP0402955B1 Solid preparation administering instrument 失效
标题翻译：一个管理工具，用于插入固体药物。
公开(公告)号：EP0402955B1
公开(公告)日：1994-03-09
申请号：EP90112505.4
申请日：1987-07-29
申请人： SUMITOMO PHARMACEUTICALS COMPANY, LIMITED
发明人： Fujioka, Keiji , Sato, Shigeji , Tamura, Nobuhiko , Takada, Yoshihiro , Sasaki, Yoshio
IPC分类号： A61M36/00
CPC分类号： A61M37/0069

42. 发明公开

EP0606212A4 TUNGSTEN-188/CARRIER-FREE RHENIUM-188 PERRHENIC ACID GENERATOR SYSTEM. 失效
标题翻译：肩带发电机系统钨-188 /铼-188，基于PERRHENISCHEN酸。
公开(公告)号：EP0606212A4
公开(公告)日：1994-01-20
申请号：EP92912654
申请日：1992-04-23
申请人： MARTIN MARIETTA ENERGY SYSTEMS
发明人： KNAPP FURN F JR , LISIC EDWARD C , MIRZADEH SAED , CALLAHAN ALVIN P
IPC分类号： B01D15/08 , A61K51/12 , C01G47/00 , G21G4/08 , A61K43/00 , A61M36/00 , B01D15/00 , G01N30/00
CPC分类号： G21G1/0005 , A61K51/1282 , A61K2121/00 , G21G2001/0073

43. 发明公开

EP0522803A1 Injector 失效
标题翻译：注射器
公开(公告)号：EP0522803A1
公开(公告)日：1993-01-13
申请号：EP92306147.7
申请日：1992-07-03
申请人： TEXAS INSTRUMENTS INCORPORATED , TEXAS INSTRUMENTS HOLLAND B.V.
发明人： Niezink, Herman , Benning, Franciscus H.C.
IPC分类号： A61M36/00
CPC分类号： A61M37/0069
摘要： Injector (1), comprising a housing to which is fixed a hollow needle (17) provided with conveyance means (3,4) for moving an object such as a transponder (22) through said needle (17). Such transponders (22) are inserted in living beings for identification purposes. Metering means (11,12) are provided in the injector (1) in order to permit the introduction of a fluid such as a disinfectant during the insertion of such objects (22). Such means comprise a storage place for fluid (11) which is connected to channel means (8) which open into the movement path of the object (22). In this way fluid is added during the positioning of the object (22).
摘要翻译：包括壳体的注射器（1）固定有中空针（17），该中空针设置有用于将诸如应答器（22）的物体移动通过所述针（17）的输送装置（3,4）。这种应答器（22）插入生物体中用于识别目的。计量装置（11,12）设置在注射器（1）中，以便在插入这些物体（22）期间允许引入诸如消毒剂的流体。这种装置包括用于流体（11）的存储位置，该存储位置连接到通向物体（22）的运动路径的通道装置（8）。以这种方式在物体（22）的定位期间添加流体。

44. 发明公开

EP0292936A3 Device for administering solid preparations 失效
标题翻译：用于管理固体制剂的装置
公开(公告)号：EP0292936A3
公开(公告)日：1991-04-03
申请号：EP88108328.1
申请日：1988-05-25
申请人： SUMITOMO PHARMACEUTICALS COMPANY, LIMITED , NISSHO CORPORATION
发明人： Fujioka, Keiji , Tamura, Nobuhiko , Takada, Yoshihiro , Himeshima, Kenji
IPC分类号： A61M36/00
CPC分类号： A61M37/0069
摘要： A device for administering solid or semisolid preparations in an organism subcutaneously. The equipment comprises a barrel (3) having a nozzle (5) for attachment of a hollow needle (4), a plunger (2) slidably arranged in the barrel and is used in combination with a guide member (15) adapted to be snugly accommodated within the lumen of the barrel. The solid preparations (16) are generally housed in the guide member and/or needle and forced into the body subcutaneously through the needle.

45. 发明公开

EP0390916A4 DEVICE FOR THE ORAL ADMINISTRATION OF A RADIOACTIVE LIQUID 失效
标题翻译：用于放射性药物口服给药的装置
公开(公告)号：EP0390916A4
公开(公告)日：1991-03-13
申请号：EP90901098
申请日：1989-08-25
申请人： MALLINCKRODT, INC.
发明人： BENJAMINS, HARM, MARTINUS
IPC分类号： A61M31/00 , A61M36/00 , A61M37/00
CPC分类号： A61M31/005
摘要： The invention relates to a device for the oral administration of a radioactive liquid, comprising: a reservoir for the radioactive liquid to be enclosed within a shielding sleeve, a separate holder for rinsing liquid to be accommodated outside the sleeve, a connection tube to communicate the interior of the holder for rinsing liquid with the interior of the reservoir, and a suction tube which has such a length that one end can be provided in the interior of the reservoir and the other end, namely the suction end, can reach the patient's mouth, in which: the reservoir is sealed by means of a pierceable rubber stopper, the ends of the connection tube and of the suction tube, which permit communication with the interior of the reservoir, comprise hollow needles, and the connection tube comprises a one-way valve to prevent radioactive liquid from flowing from the reservoir into the holder for rinsing liquid.

46. 发明公开

EP0366214A2 Improved adaptor for remote after-loading apparatus for radiotherapy 失效
标题翻译：适配器Fern-Nachladegerätzur Strahlentherapie。
公开(公告)号：EP0366214A2
公开(公告)日：1990-05-02
申请号：EP89202710.3
申请日：1989-10-27
申请人： Van 't Hooft, Eric
发明人： van t' Hooft, Eric , van Zwol, Libbe
IPC分类号： A61N5/10 , A61M36/00 , A61B6/00
CPC分类号： A61N5/1007 , A61N2005/1008
摘要： The adaptor for connecting a guide member in a remote after-loading apparatus for radiotherapy is provided. The adaptor comprises an outer barrel (80) having an opened end, a connector end and a centrally extending aperture. A sleeve (92) passes through the aperture of the barrel such that at least a first end of the sleeve is contained within the barrel. An elongated gripping means (84) is disposed through the sleeve and extends beyond the ends of the sleeve. The gripping means has a gripping end and a receiving end, a gripping body extending between the ends, and a flange (83) disposed on the gripping end with the diameter of the flange being greater than the diameter of the sleeve. A tapered outer surface (95) extends from the flange to a distant portion of the gripping body. A uniform diameter tube bore is disposed through the gripping means and at least two slots (99) pass through the flange and at least a portion of the gripping body. Those slots form at least two opposed gripping portions which are inwardly compressible when the flange and the gripping portions are in contact with the first end of the sleeve, so as to form a reduced diameter of the tube bore and thereby a closed position of the gripping portions. The gripping portions are sufficiently resilient so that when the flange and the gripping portions are disposed from the first end of the sleeve, the gripping portions form at least the same diameter as the tube bore and thereby an open position. Spring means (41) are disposed between the gripping means in the sleeve for urging the flange of the gripping means toward the second end of the sleeve.
摘要翻译：提供用于连接用于放射治疗的远程后加载装置中的引导构件的适配器。适配器包括具有开口端的外筒（80），连接器端和中心延伸的孔。套筒（92）通过筒体的孔，使得套筒的至少第一端容纳在筒体内。细长的夹持装置（84）穿过套筒设置并延伸超过套筒的端部。夹持装置具有夹持端和接收端，在端部之间延伸的夹持体和设置在抓持端上的凸缘（83），凸缘的直径大于套筒的直径。锥形外表面（95）从凸缘延伸到抓握体的远侧部分。均匀直径的管孔穿过夹持装置设置，并且至少两个槽（99）穿过凸缘和夹持体的至少一部分。这些槽形成至少两个相对的夹持部分，当把法兰和夹持部分与套筒的第一端接触时，它们可向内压缩，从而形成管孔的直径减小，从而形成夹紧的闭合位置部分。抓握部分具有足够的弹性，使得当凸缘和抓握部分从套筒的第一端设置时，抓握部分形成至少与管孔相同的直径，从而形成打开位置。弹簧装置（41）设置在套筒中的夹持装置之间，用于将夹持装置的凸缘朝向套筒的第二端推动。

47. 发明公开

EP0210875A2 Apparatus for delivering insoluble material into a living body and method of use thereof 失效
标题翻译：装置，用于在活体中引入的不溶性物质并使用该设备。
公开(公告)号：EP0210875A2
公开(公告)日：1987-02-04
申请号：EP86305970.5
申请日：1986-08-01
申请人： THERAGENICS CORPORATION
发明人： Russell, John Lynn, Jr. , Carden, John Lewis, Jr.
IPC分类号： A61M36/00
CPC分类号： A61M5/1414 , A61M5/007 , A61M2005/1403 , A61N5/1007 , A61N2005/1021 , Y10S604/903
摘要： To deliver a controlled dosage of an insoluble material into a living body, the material is provided in measured amounts in vials (12), and a system is provided forflushing the entire content of insoluble materials from the vial into the body. Insoluble radioactive material, such as glass microspheres incorporating radioactive isotopes, are packaged in a plurality of vials, preferably with different amounts of material. An accurate dosage of radioactivity can be delivered by administering the entire contents of one or more vial(s) according to the sum of radioactivity in selected vials as determined by the initial measurement of radioactivity and by the natural half-life of the isotope.
摘要翻译：为了提供一种不溶性材料的受控剂量到生物体内，该材料在测量的量提供在小瓶（12），并提供了一种用于冲洗不溶物从小瓶的全部内容到体内的系统。不溶放射性材料，颜色：诸如玻璃微球掺入放射性同位素，被包装在小瓶的复数，优选用材料的不同的量。放射性的精确剂量可通过在选定小瓶确定性通过放射性的初始测量开采施用一种或多种小瓶（S）雅丁到放射性的总和的全部内容，并通过同位素的天然半衰期来递送。

48. 发明公开

EP3833705A1 CROSS-LINKED RADIOPAQUE BIORESORBABLE POLYMERS AND DEVICES MADE THEREFROM 审中-公开
公开(公告)号：EP3833705A1
公开(公告)日：2021-06-16
申请号：EP19847796.0
申请日：2019-08-07
申请人： Reva Medical, LLC
发明人： SCHULTZ, Robert, K. , KABALNOVA, Lioubov , BRANDOM, Donald, K. , EARLEY, Jessica , BALUCA, Ernest, G.
IPC分类号： C08G63/64 , C08G63/06 , C08G64/12 , C08G65/40 , A61K49/04 , A61K47/34 , A61K51/00 , A61M36/14 , A61M36/00

49. 发明公开

EP3696824A1 RUBIDIUM ELUTION SYSTEM CONTROL 有权
公开(公告)号：EP3696824A1
公开(公告)日：2020-08-19
申请号：EP20166557.7
申请日：2012-10-26
申请人： Jubilant Draximage, Inc. , Ottawa Heart Institute Research Corporation
发明人： LEFORT, Étienne , TEOLI, Vincenzo , DEKEMP, Robert A. , KLEIN, Ran
IPC分类号： G21G1/00 , A61K51/00 , A61M36/00 , A61K51/12
摘要： Embodiments of the present invention provide for assessing the state of an 82 Rb elution system. In certain embodiments, a system begins an assessment that comprises an elution, and a metric may be measured. This metric may be a concentration of 82 Rb, 82 Sr, or 85 Sr in a fluid that is eluted from the generator, the volume of the fluid that is eluted from the generator, or the pressure of the fluid flowing through at least one portion of the system. If the assessment is completed, an output may be generated on a user interface that recommends a course of action, or no course of action, based on a result of the assessment. Should the assessment not complete successfully because it is interrupted, a 82 Sr/ 82 Rb generator of the system may be halted so as to prevent a user from performing an end-run around these quality control mechanisms of the 82 Rb elution system. Further, in response to determining that a total volume of the fluid exceeds a limit threshold, elution is prevented until the generator is replaced with a new generator.

50. 发明公开

EP3533494A1 BRACHYTHERAPY APPARATUS 无效
公开(公告)号：EP3533494A1
公开(公告)日：2019-09-04
申请号：EP19166645.2
申请日：2006-11-06
申请人： Cianna Medical, Inc.
发明人： Hermann, George D. , Chi Sing, Eduardo , Lebovic, Gail S. , Cole, Marl A. , Ritchart, Mark A. , Nguyen, Than
IPC分类号： A61N5/10 , A61M36/00
摘要： A brachytherapy treatment apparatus for treating tissue surrounding a cavity within a body includes an elongate body comprising a proximal end and a distal end sized for introduction into a tract through tissue and a plurality of tubular members on the distal end comprising lumens for receiving a source of radiation therein. The tubular members are movable from a collapsed configuration for introduction through a tissue tract to a target location, and an expanded configuration for providing a three dimensional array of pathways at the target location. A plurality of openings communicating with respective lumens for inserting the source of radiation into the lumens are provided and a hub is coupled to proximal ends of the tubular members. The hub is movable relative to the elongate body for moving the tubular members from the collapsed configuration to the expanded configuration. An actuator for moving the hub relative to the distal end is also provided.

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