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    • 41. 发明公开
    • COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST
    • “配位化合物催化剂制造方法配合物催化剂和方法用于生产具有复杂CATALYST醇衍生物”
    • EP1380342A4
    • 2004-09-29
    • EP02720443
    • 2002-04-17
    • SUMITOMO CHEMICAL CO
    • SASAKI KAZUAKI
    • B01J31/18B01J31/22C07D213/64B01J27/20C07B53/00C07C41/03C07C43/23
    • B01J31/2243B01J2231/48B01J2531/0252B01J2531/60B01J2531/72B01J2531/845C07D213/64
    • An (asymmetric) complex catalyst comprising a Lewis acid and a metal complex represented by the formula (1): (wherein R?1, R2, R3, R4, R5, R6, R7, and R8¿ are the same or different and each represents hydrogen, halogeno, alkyl, etc.; one of R?9 and R10¿ represents hydrogen and the other represents C¿1-4? alkyl, etc.; Q represents a single bond, C1-4 alkylene, etc.; M represents a metal ion; and A represents a counter ion or ligand for balancing); a process for producing an (optically active) alcohol derivative, characterized by reacting a cyclic ether compound with a phenol derivative in the presence of the complex catalyst; and a process for producing an (optically active) nitrogenous heterocyclic compound which comprises reacting the alcohol derivative with a halogenated nitrogenous heterocyclic compound in the presence of a base.
    • 本发明提供(非对称)配合物催化剂,其包括金属配合物和路易斯酸作为成分,金属配合物的存在的式(1): worin - [R <1>,R <2> [R <3>,R <4> ,R <5> - [R <6>,R氢<7>和R <8>是相同的或不同的并且是unabhängig,卤素,烷基等; [R <9>和R中的一个<10>是氢,另一个是1至4个碳原子等的烷基; Q是单键或具有1至4个碳原子的亚烷基; M是金属离子; 且A是一个平衡抗衡离子或配体; 用于生产合成络合物催化剂的过程; 用于生产(光学活性)醇衍生物,其特征在于DASS环状醚化合物的方法进行反应,在合成配合物催化剂的存在下苯酚的衍生物; 和用于产生进一步处理(光学活性)通过使合成醇衍生物在碱的存在下卤代含氮杂环化合物的杂环含氮化合物。