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41. 发明公开

EP3965776A1 OLIGOSACCHARIDE COMPOSITIONS AND METHODS OF USE 无效转让
公开(公告)号：EP3965776A1
公开(公告)日：2022-03-16
申请号：EP20802108.9
申请日：2020-05-08
申请人： Kaleido Biosciences, Inc.
发明人： YATSUNENKO, Tatyana , LAWRENCE, Jonathan , ROSINI, Madeline , HECHT, Max , LIU, Christopher, Matthew
IPC分类号： A61K31/702 , A61K35/741 , A61P1/00

43. 发明公开

EP3904502A3 COMPOSITIONS AND METHODS 审中-公开
公开(公告)号：EP3904502A3
公开(公告)日：2022-02-23
申请号：EP21156987.6
申请日：2014-02-04
申请人： Seres Therapeutics, Inc.
发明人： AFEYAN, Noubar, B. , MCKENZIE, Mary-Jane, Lombardo , LITCOFSKY, Kevin, Daniel , COOK, David, N. , HENN, Matthew, R. , VON MALTZAHN, Geoffrey
IPC分类号： C12N1/20 , A61K35/741
摘要： Provided are defined bacterial compositions for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for populating the gastrointestinal tract of a subject. Provided also are bacterial formulations for oral or gastric administration to a mammalian subject in an effective amount for prevention or treatment of a gastrointestinal disease, disorder or condition.

44. 发明公开

EP3947702A1 METHOD OF PRODUCING BACTERIALLY DERIVED INDOLE-3 -PROPIONIC ACID AND COMPOSITIONS COMPRISING SAME 审中-公开
公开(公告)号：EP3947702A1
公开(公告)日：2022-02-09
申请号：EP20722413.0
申请日：2020-04-02
申请人： The Procter & Gamble Company
发明人： VENKATARAMAN, Arvind , BREWSTER, Chelsay, Lynn , KOZAK, Kimberly, Conner , LI, Lijuan , STAMPER, Jason, Allen
IPC分类号： C12P7/40 , C12P17/10 , A61P25/28 , C12N9/14 , C12N1/20 , A61K31/405 , A61K35/741

45. 发明公开

EP3937968A1 TRANSGENIC PROBIOTIC E. COLI CELL 审中-公开
公开(公告)号：EP3937968A1
公开(公告)日：2022-01-19
申请号：EP20713218.4
申请日：2020-03-13
申请人： Freie Universität Berlin
发明人： TEDIN, Lydia , TEDIN, Karsten , HARTMANN, Susanne
IPC分类号： A61K38/16 , A61K35/741 , C07K14/435

46. 发明公开

EP3911341A1 FERMENTED FORMULA WITH NON-DIGESTIBLE OLIGOSACCHARIDES FOR USE IN ROTAVIRUS INDUCED INFECTION 有权
公开(公告)号：EP3911341A1
公开(公告)日：2021-11-24
申请号：EP20702576.8
申请日：2020-01-16
申请人： N.V. Nutricia
发明人： KNIPPING, Catharina Theresia , PÉREZ CANO, Francisco José , GARSSEN, Johan
IPC分类号： A61K35/20 , A61K31/702 , A61K35/741 , A61K35/744 , A61K35/745 , A23L33/00 , A23L33/135 , A23L33/21 , A61P1/12 , A23K50/75 , A23K20/121

47. 发明公开

EP3903824A1 SKIN PROBIOTIC 无效
公开(公告)号：EP3903824A1
公开(公告)日：2021-11-03
申请号：EP21173449.6
申请日：2015-01-10
申请人： The Regents of the University of California
发明人： HUANG, Chun-Ming
IPC分类号： A61K45/06 , A61K9/06 , A61K35/741 , A61K31/19 , A61K31/22 , A61K31/225 , A61K31/047 , A61K31/194 , A61P17/00 , C12Q1/04
摘要： The present invention relates to a topical probiotic composition for producing or maintaining skin microbiome balance, the composition comprising a therapeutically effective amount or inhibiting effective amount one or more compounds having the structure of Formula I:

wherein R, R 1 , and R 2 are independently selected from the group consisting of hydrogen, and optionally substituted (C 1 -C 12 ) alkyl, optionally substituted hetero- (C 1 -C 12 ) alkyl, optionally substituted (C 1 -C 12 ) alkenyl, optionally substituted hetero- (C 1 -C 12 ) alkenyl, optionally substituted (C 1 -C 12 ) alkynyl, optionally substituted hetero- (C 1- C 12 ) alkynyl, optionally substituted (C 1 -C 12 ) cycloalkyl, optionally substituted (C 1 -C 12 ) cycloalkenyl, optionally substituted aryl, optionally substituted heterocycle, and optionally substituted mixed ring system, and -O-R 3 -O-Y; R3 is selected from the group consisting of an optionally substituted (C 1 -C 12 ) alkyl, optionally substituted hetero- (C 1 -C 12 ) alkyl, optionally substituted (C 1 -C 12 ) alkenyl, optionally substituted hetero- (C 1 -C 12 ) alkenyl, optionally substituted (C 1 -C 12 ) alkynyl, and optionally substituted hetero- (C 1 -C 12 ) alkynyl; and Y is another compound of Formula I, or is selected from the group consisting of

and pharmaceutically acceptable salts thereof.

48. 发明公开

EP3881680A1 METHODS AND COMPOSITIONS RELATING TO MICROBIAL TREATMENT 审中-实审
公开(公告)号：EP3881680A1
公开(公告)日：2021-09-22
申请号：EP21157228.4
申请日：2015-10-30
申请人： Pendulum Therapeutics, Inc.
发明人： CUTCLIFFE, Colleen , EID, John S. , BULLARD, James H. , SCHICKLBERGER, Marcus F.
IPC分类号： A01N63/00 , C12N1/20 , A61K31/733 , A61K35/74 , A61K45/06 , A23L33/135 , A61K35/741 , A61K35/00 , A61P3/00 , A61P3/04 , A61P3/10
摘要： The present disclosure provides methods, systems, compositions, and kits to address the need for microbiome-related treatment of health conditions and disease. The present disclosure provides for treatment of metabolic conditions using microbial compositions.

49. 发明公开

EP3870691A1 METHODS AND COMPOSITIONS FOR TREATING GASTROINTESTINAL AND INFLAMMATORY DISORDERS 审中-公开
公开(公告)号：EP3870691A1
公开(公告)日：2021-09-01
申请号：EP19860239.3
申请日：2019-09-13
申请人： Assembly Biosciences, Inc.
发明人： PAPKOFF, Jackie , MA, Jun
IPC分类号： C12N1/20 , C12R1/01 , A61K35/741 , A61K35/74

50. 发明公开

EP3860629A1 MICROBIAL ANALYSIS WITHOUT CELL PURIFICATION 审中-实审
公开(公告)号：EP3860629A1
公开(公告)日：2021-08-11
申请号：EP19870007.2
申请日：2019-10-04
申请人： First Light Diagnostics, Inc.
发明人： STRAUS, Don
IPC分类号： A61K35/741 , A61K35/742 , A61K9/00

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