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31. 发明公开

EP3024415A1 ADVANCING GENETIC GAIN IN BOVINE 审中-公开
标题翻译： VERMEHRUNG DES GENETISCHEN ERTRAGS VON RINDERN
公开(公告)号：EP3024415A1
公开(公告)日：2016-06-01
申请号：EP14829184.2
申请日：2014-07-23
申请人： Barfield, Jennifer , Webb, Brandon, L.
发明人： Barfield, Jennifer , Webb, Brandon, L.
IPC分类号： A61D19/00
CPC分类号： A01K67/02 , A01K67/027 , A01K2207/20 , A01K2227/101 , A61D19/02 , A61D19/04 , A61K31/57 , A61K38/24
摘要： This invention relates to a method for reducing the generation interval and advancing genetic gain in bovines via pregnancies created by oocytes harvested from select prepubertal female calves less than six months of age and/or from smaller framed bovine breeds less than ten months of age, and alternatively less than nine months of age. Said animals are treated with a hormone regiment to advance the first pubertal estrus in order to retrieve oocytes for fertilization and implantation. Oocytes are collected from said animals via laparoscopic aspiration. In the case of oocytes that have not matured in vivo, the oocytes are transferred to and cultured to maturation. Once matured, oocytes are fertilized, and the resultant embryos are transferred to synchronized recipients.
摘要翻译：本发明涉及通过从少于六个月龄的选择性青春期前雌性小牛收获的卵母细胞和/或小于十个月龄的较小框架的牛品种产生的怀孕产生的妊娠来减少牛的产生间隔和促进遗传增益的方法，以及或者不到九个月。所述动物用激素团治疗以促进第一次青春期发情，以获取卵母细胞进行受精和植入。通过腹腔镜抽吸从所述动物收集卵母细胞。在体内未成熟的卵母细胞的情况下，将卵母细胞转移并培养成熟。一旦成熟，卵母细胞受精，并将所得的胚胎转移到同步的受体。

32. 发明公开

EP2872212A4 METHODS FOR IMPROVING MALE FERTILITY 审中-公开
标题翻译：方法提高的雄性能育
公开(公告)号：EP2872212A4
公开(公告)日：2016-06-01
申请号：EP13817298
申请日：2013-07-11
申请人： TEL HASHOMER MEDICAL RES INFRASTRUCTURE & SERVICES LTD
发明人： RAVIV GIL , SHASHAR DAVID , SHADMI YORAM , SHVITLOWSKY ITZCHAK , CASTEL DAVID
IPC分类号： A61N1/20 , A61B5/00 , A61B10/00 , A61D19/00 , A61N1/04 , A61N1/36
CPC分类号： A61N1/205 , A61B5/4387 , A61B5/4836 , A61B10/0058 , A61B2503/40 , A61D19/00 , A61N1/0408 , A61N1/0492 , A61N1/36007 , F04C2270/041
摘要： The present invention is directed to methods for improving male fertility inter alia by increasing sperm count in a male subject. The methods of the invention comprise applying a positive electrical current below sensation level to at least one site of a scrotum of a subject in need thereof.

33. 发明公开

EP3003210A1 IVF EGG COLLECTION CHAMBER 有权转让
标题翻译： IVF-EGG-SAMMELKAMMER
公开(公告)号：EP3003210A1
公开(公告)日：2016-04-13
申请号：EP14728258.6
申请日：2014-05-30
申请人： Labman Automation Ltd , University of Newcastle Upon Tyne , The Newcastle Upon Tyne Hospitals NHS Foundation Trust
发明人： HODGSON, Robert , MURDOCH, Alison
IPC分类号： A61D19/04 , A61B17/435
CPC分类号： A61B17/435 , A61D19/04 , C12M33/14
摘要： The present invention relates to egg chambers for use in collection, inspection and selection of eggs for in vitro fertilisation (IVF) procedures. The egg chamber, in use, provides an effectively closed and fluid filled system which minimises the environmental changes that a harvested egg is exposed to, thus maximising viability. The egg chamber comprises a vessel which can be made airtight, comprising at least one side wall, an upper wall and a lower wall, at least a portion of the upper wall being transparent and at least a portion of the lower wall being light permeable; a first inlet with a sealable port; a first outlet with a sealable port; a filter with a pore size appropriate for egg collection disposed within the vessel between the first inlet and the first outlet and configured to separate the vessel into a first internal chamber and a second internal chamber.
摘要翻译：本发明涉及用于收集，检查和选择用于体外受精（IVF）方法的卵的蛋室。在使用中的蛋室提供了一种有效封闭和充满流体的系统，其最小化收获的鸡蛋暴露于环境变化，从而最大化生存力。蛋室包括可以制成气密的容器，其包括至少一个侧壁，上壁和下壁，所述上壁的至少一部分是透明的，并且所述下壁的至少一部分是透光的; 具有可密封端口的第一入口; 具有密封端口的第一个出口; 具有适于收集鸡蛋的孔径的过滤器，其设置在第一入口和第一出口之间的容器内，并且构造成将容器分离成第一内室和第二内室。

34. 发明公开

EP2910217A1 Paillette pour la conservation d'une dose prédéterminée de substance à base liquide, notamment une substance biologique 有权
标题翻译：血小板用于在液体碱的物质的特定剂量的存储，特别是生物物质
公开(公告)号：EP2910217A1
公开(公告)日：2015-08-26
申请号：EP15155871.5
申请日：2015-02-20
申请人： IMV Technologies
发明人： Schmitt, Eric , Gorges, Jean-Charles
IPC分类号： A61D19/02
摘要： La paillette comporte un tube (11) ayant un tampon gonflant (15) pourvu d'un agent de support fibreux et d'un agent de gonflement associé à l'agent de support et configuré pour être, au moins au voisinage d'une seconde extrémité (18) du tampon gonflant, après qu'une substance à base liquide a rencontré sa seconde extrémité, dans un état de gonflement contrarié par ledit tube tel que si une première partie (26) du tampon gonflant de longueur comprise entre 2 mm et 3 mm à partir de sa seconde extrémité est sortie du tube par une seconde extrémité (14) du tube, alors qu'une seconde partie du tampon gonflant reste dans le tube, la première partie du tampon gonflant se décompacte et s'épanouit avec la seconde extrémité du tampon gonflant qui prend un diamètre (d) au moins égal à une fois et demi le diamètre interne du tube.

35. 发明授权

EP2341129B1 SEX-SPECIFIC INSEMINATION OF MAMMALS WITH LOW NUMBER OF SPERM CELLS 有权
标题翻译：与精子数量少兽类性别特异性人工授精
公开(公告)号：EP2341129B1
公开(公告)日：2015-06-10
申请号：EP10185715.9
申请日：1998-12-31
申请人： XY, LLC
发明人： Seidel, George E. , Herickhoff, Lisa , Schenk, John
IPC分类号： C12N5/076 , A61D19/02 , A01K67/02 , A01K67/027 , C12N15/873
CPC分类号： C12N5/0612 , A01K67/027 , A61D19/02 , C12N15/873 , G01N2015/149

36. 发明公开

EP2852462A1 TEST TUBE WITH IDENTIFICATION DEVICE AND CORRESPONDING PRODUCTION METHOD 有权
标题翻译：具有识别设备和相关的方法试管
公开(公告)号：EP2852462A1
公开(公告)日：2015-04-01
申请号：EP13737364.3
申请日：2013-05-23
申请人： Biosigma Srl
发明人： DUTSCHER, Dominique, Charles, Joseph , MARCOLIN, Martino , TAMIAZZO, Francesco , VERONESE, Valter
IPC分类号： B01L3/14 , A61D19/02 , G01N1/42 , A01N1/02 , B01L3/00
CPC分类号： A01N1/0268 , B01L3/502 , B01L3/5453 , B01L2300/022 , B01L2300/0832 , B01L2300/0851 , B01L2300/0858 , B01L2300/1894 , C12M45/22 , G01N1/42 , Y10T29/49826
摘要： A test tube, suitable to be immersed in a cryogenic fluid, comprises a containing body having a perimeter wall that defines a containing compartment, a bottom wall, disposed inside the latter to close it at the lower part, and a housing seating, inside the perimeter wall and outside the containing compartment. A support element for an identification code is suitable to be inserted into the housing seating, with at least a free surface facing toward the outside of the housing seating on the opposite side with respect to the bottom wall. In correspondence to said housing seating, mechanical constraint means are provided in cooperation with said perimeter wall of the containing body and with a peripheral portion of the free surface of the support element, in order to constrain the latter in a defined axial position with respect to the containing body.

37. 发明公开

EP2787810A1 INORGANIC PYROPHOSPHATE AND USES THEREOF 审中-公开
标题翻译： VORWENDUNGEN DAVON的异氰酸磷酸盐
公开(公告)号：EP2787810A1
公开(公告)日：2014-10-15
申请号：EP12855337.7
申请日：2012-12-07
申请人： The Curators Of The University Of Missouri
发明人： SUTOVSKY, Peter , YI, Young-joo
IPC分类号： A01N1/02 , A61D19/02 , A61D19/04
CPC分类号： A61B17/43 , A01N1/0226 , A61D19/02 , C12N5/0604 , C12N5/0609 , C12N5/061 , C12N5/0612 , C12N2500/05 , C12N2517/10 , G01N33/5005
摘要： The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mammalian oocytes matured in vitro in a medium including PPi attain improved fertilization and developmental potential, while embryos cultured in medium supplemented with PPi have improved development to blastocyst.
摘要翻译：本发明提供了一种新的和改进的精子刺激添加剂，其包含一定量的无机焦磷酸盐（PPi）。用于人/动物体外受精（IVF）的培养基中添加PPi可提高受精率; 用于农场动物人工授精的精液延长剂中添加PPi可能会提高妊娠率; 此外，在包括PPi的培养基中体外成熟的哺乳动物卵母细胞获得改善的受精和发育潜力，而在补充有PPi的培养基中培养的胚胎已经改善了囊胚发育。

38. 发明公开

EP2718022A1 METHOD TO DISCHARGE A FLUID, CONTAINER AND HEATING DEVICE 审中-公开
标题翻译：程序刊发的液体容器和加热装置
公开(公告)号：EP2718022A1
公开(公告)日：2014-04-16
申请号：EP12730672.8
申请日：2012-06-05
申请人： Kinetic Inventions BV
发明人： GIESBERTS, Robert Bram , VRERIKS, Michiel Gerard
IPC分类号： B05B11/00 , B05B11/06 , A61M35/00 , A45D27/02 , A61D19/02 , B05C17/005
CPC分类号： A45D34/00 , A45D2200/054 , A45D2200/055 , A45D2200/155 , A61D19/025 , B05B9/002 , B05B9/0844 , B65D83/72
摘要： The invention is directed to a method to discharge a fluid from a container, wherein the container comprises a reservoir for the fluid and an outlet opening for the fluid which outlet opening is fluidly connected to the reservoir by means of a conduit, wherein the fluid is increased in temperature as it is discharged from said container by direct heat exchange between the fluid and the internal wall of the conduit and wherein the wall of the conduit is increased in temperature by means of friction between the exterior wall of the conduit and a friction member which is moved relative to the exterior wall of the conduit.

39. 发明公开

EP2353543A4 DEVICE AND METHOD FOR INSERTING OR OBTAINING A FLUID WITH GAMETES, EMBRYOS OR ANY OTHER TYPE OF SOLUTION IN THE OVIDUCT OF A SOW 有权
标题翻译：装置和方法引入或获得生殖细胞，胚或解决方案的任何其他类型的输卵管VION母亲猪液体
公开(公告)号：EP2353543A4
公开(公告)日：2014-04-09
申请号：EP09815714
申请日：2009-09-24
申请人： UNIV MURCIA
发明人： VAZQUEZ ROJAS JUAN MARIA , MARTINEZ GARCIA EMILIO , VAZQUEZ ROJAS JOSE LUIS , ROCA ALEU JORGE
IPC分类号： A61D19/02 , A61B17/34 , A61B19/08 , A61D19/04
CPC分类号： A61D19/04 , A61B10/0045 , A61B10/0291 , A61B17/3478 , A61B46/13 , A61D19/027

40. 发明公开

EP2341129A3 Sex-specific insemination of mammals with low number of sperm cells 有权
标题翻译：哺乳动物的性别特异性受精精子数量少
公开(公告)号：EP2341129A3
公开(公告)日：2013-11-06
申请号：EP10185715.9
申请日：1998-12-31
申请人： XY, LLC
发明人： Seidel, George E. , Herickhoff, Lisa , Schenk, John
IPC分类号： C12N5/076 , A61D19/02 , A01K67/02 , A01K67/027 , C12N15/873
CPC分类号： C12N5/0612 , A01K67/027 , A61D19/02 , C12N15/873 , G01N2015/149
摘要： Artificial Insemination is achieved for sexed mammalian offspring in a commercially practical manner and with dosages of insemination sperm which were not previously thought to be practical for commercial implementation. Improved insemination systems particularly adapted to use for sex-selected sperm sorting include systems which achieve superovulation and then multiple embryo production with sexed embryos. These systems combine with other techniques, including techniques for enhanced sheath fluid (3) and other strategies which minimize stress on the sperm cells (18), and potentially, a 2.9 percent sodium citrate sheath solution for bovine species and a hepes bovine gamete media for equine species. Improved collection systems (14) and techniques for the process are describeb so that commercial application of sperm samples as well as the resulting animals may now be achieved in the field.

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